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Literature for peptidase S01.001: chymotrypsin A (cattle-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

(Topics flags: S Structure, A Assay, P Specificity, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Zhou,S., Liu,C., Shi,H. and Gao,L.
    Highly Sensitive Detection of Chymotrypsin Using Gold Nanoclusters with Peptide Sensors
    Micromachines (Basel) (2026) 17 PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2025
  2. Stefan,A. and Hochkoeppler,A.
    The catalytic action of enzymes exposed to charged substrates outperforms the activity exerted on their neutral counterparts
    Biochem Biophys Res Commun (2025) 751, 151436-151436. PubMed  Europe PubMed DOI
    3. 2024
  3. Ansari,N.K., Khan,H.S. and Naeem,A.
    Doxorubicin as a Drug Repurposing for Disruption of alpha-Chymotrypsinogen-A Aggregates
    Protein J (2024) 43, 842-857. PubMed  Europe PubMed DOI
  4. Gajardo-Parra,N.F., Cea-Klapp,E., Chandra,A., Canales,R., Garrido,J.M., Held,C. and Guajardo,N.V.
    Assessing the effect of deep eutectic solvents on alpha-chymotrypsin thermal stability and activity
    ChemSusChem (2024) , e202401414-e202401414. PubMed  Europe PubMed DOI
  5. Gholizadeh,M., Shareghi,B. and Farhadian,S.
    Revealing the interaction between alpha-chymotrypsin and eugenol: An integrated multi-spectral and dynamic simulation approach
    Int J Biol Macromol (2024) 277, 134504-134504. PubMed  Europe PubMed DOI
  6. Patel,C.K. and Mukherjee,T.K.
    Biomolecular Condensation of Trypsin Prevents Autolysis and Promotes Ca(2+)-Mediated Activation of Esterase Activity
    Biomacromolecules (2024) 25, 6082-6092. PubMed  Europe PubMed DOI
  7. Shirazi,S.H., Rizvi,F., Sherwani,Z.A., Siddiqui,A.R., Ul-Haq,Z., Siddiqui,H., Choudhary,M.I. and Ahmad,M.S.
    Synthesis of isoniazid derivatives and evaluation of their alpha-chymotrypsin inhibitory effect through in silico guided in vitro studies
    Biochem Biophys Res Commun (2024) 735, 150805-150805. PubMed  Europe PubMed DOI  I
  8. Sindhikara,D., Iskandar,S.E., Guan,L., Maini,R., Hipolito,C.J., Sun,C., Vasicek,L.A., Weinglass,A. and Saldanha,S.A.
    Analysis and Prediction of Chymotrypsin Substrate Preferences through Large Data Acquisition with Target-Free mRNA Display
    Chembiochem (2024) , e202400760-e202400760. PubMed  Europe PubMed DOI
  9. Yadav,B., Yadav,N. and Venkatesu,P.
    Unravelling the stabilization mechanism of mono-, di- and tri-cholinium citrate-ethylene glycol DESs towards alpha-chymotrypsin for preservation and activation of the enzyme
    Phys Chem Chem Phys (2024) 26, 28025-28036. PubMed  Europe PubMed DOI
  10. Ying,Y. and Li,H.
    Native top-down mass spectrometry for monitoring the rapid chymotrypsin catalyzed hydrolysis reaction
    Anal Chim Acta (2024) 1285, 341971-341971. PubMed  Europe PubMed DOI
    11. 2023
  11. Solovyev,M., Kashinskaya,E. and Gisbert,E.
    A meta-analysis for assessing the contributions of trypsin and chymotrypsin as the two major endoproteases in protein hydrolysis in fish intestine
    Comp Biochem Physiol A Mol Integr Physiol (2023) 278, 111372-111372. PubMed  Europe PubMed DOI
  12. Vreeke,G.J.C., Vincken,J.P. and Wierenga,P.A.
    The path of proteolysis by bovine chymotrypsin
    Food Res Int (2023) 165, 112485-112485. PubMed  Europe PubMed DOI
    13. 2022
  13. Balabushevich,N.G., Kovalenko,E.A., Filatova,L.Y., Kirzhanova,E.A., Mikhalchik,E.V., Volodkin,D. and Vikulina,A.S.
    Hybrid Mucin-Vaterite Microspheres for Delivery of Proteolytic Enzyme Chymotrypsin
    Macromol Biosci (2022) 22, e2200005-e2200005. PubMed  Europe PubMed DOI
  14. Biswas,P., Adhikari,A., Pal,U., Mondal,S., Mukherjee,D., Ghosh,R., Obaid,R.J., Moussa,Z., Choudhury,S.S., Ahmed,S.A., Das,R. and Pal,S.K.
    A combined spectroscopic and molecular modeling Study on structure-function-dynamics under chemical modification: Alpha-chymotrypsin with formalin preservative
    Front Chem (2022) 10, 978668-978668. PubMed  Europe PubMed DOI  PMC  EPMC
  15. Gul,S. and Khan,A.M.
    Molecular docking studies of isolated marine natural products against alpha-chymotrypsin
    Nat Prod Res (2022) , 1-4. PubMed  Europe PubMed DOI
  16. Lan,T., Tian,Q.Q., Li,M.H. and He,W.
    Activatable endoplasmic reticulum-targeted NIR fluorescent probe with a large Stokes shift for detecting and imaging chymotrypsin
    Analyst (2022) 147, 4098-4104. PubMed  Europe PubMed DOI
  17. Liu,K.
    Method development and optimization for measuring chymotrypsin and chymotrypsin inhibitor activities
    J Food Sci (2022) 87, 2018-2033. PubMed  Europe PubMed DOI
  18. Liu,S.Y., Zou,X., Gao,X. and Zhang,Y.Y.
    De Novo Design of a Highly Selective Nonpeptide Fluorogenic Probe for Chymotrypsin Activity Sensing in a Living System
    Anal Chem (2022) 94, 17922-17929. PubMed  Europe PubMed DOI
  19. Nemeth,B.Z., Demcsak,A., Micsonai,A., Kiss,B., Schlosser,G., Geisz,A., Hegyi,E., Sahin-Toth,M. and Pal,G.
    Arg236 in human chymotrypsin B2 (CTRB2) is a key determinant of high enzyme activity, trypsinogen degradation capacity, and protection against pancreatitis
    Biochim Biophys Acta Proteins Proteom (2022) 1870, 140831-140831. PubMed  Europe PubMed DOI  PMC  EPMC
  20. Riley,M.B., Strandquist,E., Weitzel,C.S. and Driskell,J.D.
    Structure and activity of native and thiolated alpha-chymotrypsin adsorbed onto gold nanoparticles
    Colloids Surf B Biointerfaces (2022) 220, 112867-112867. PubMed  Europe PubMed DOI
  21. Song,Y., Gong,K., Yan,H., Hong,W., Wang,L., Wu,Y., Li,W., Li,W. and Cao,Z.
    Correction: Sj7170, a unique dual-function peptide with a specific alpha-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom
    J Biol Chem (2022) 298, 102543-102543. PubMed  Europe PubMed DOI  PMC  EPMC
    22. 2021
  22. Fu,Z., Akula,S., Thorpe,M. and Hellman,L.
    Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins
    Biol Chem (2021) 402, 861-867. PubMed  Europe PubMed DOI
  23. Gault,S. and Cockell,C.S.
    Perchlorate Salts Exert a Dominant, Deleterious Effect on the Structure, Stability, and Activity of alpha-Chymotrypsin
    Astrobiology (2021) 21, 405-412. PubMed  Europe PubMed DOI
  24. Gault,S., Jaworek,M.W., Winter,R. and Cockell,C.S.
    Perchlorate salts confer psychrophilic characteristics in alpha-chymotrypsin
    Sci Rep (2021) 11, 16523-16523. PubMed  Europe PubMed DOI  PMC  EPMC
  25. Lather,J. and George,J.
    Improving Enzyme Catalytic Efficiency by Co-operative Vibrational Strong Coupling of Water
    J Phys Chem Lett (2021) 12, 379-384. PubMed  Europe PubMed DOI
  26. Li,H., Wang,Y., He,X., Chen,J., Xu,F., Liu,Z. and Zhou,Y.
    A green deep eutectic solvent modified magnetic titanium dioxide nanoparticles for the solid-phase extraction of chymotrypsin
    Talanta (2021) 230, 122341-122341. PubMed  Europe PubMed DOI
  27. Mahmoud,G.S., Hosny,G. and Sayed,S.A.
    Hepatoprotective effect of trypsin/chymotrypsin against olanzapine-induced non-alcoholic steatohepatitis in rats
    Can J Physiol Pharmacol (2021) , 1-9. PubMed  Europe PubMed DOI
  28. Piovarci,I., Hianik,T. and Ivanov,I.N.
    Detection of Chymotrypsin by Optical and Acoustic Methods
    Biosensors (Basel) (2021) 11 PubMed  Europe PubMed DOI  PMC  EPMC
  29. Zou,X., Zhao,Y., Lai,C., Liang,Y. and Lin,W.
    A non-peptide probe for detecting chymotrypsin activity based on protection-deprotection strategy in living systems
    J Mater Chem B (2021) 9, 8417-8423. PubMed  Europe PubMed DOI
    30. 2020
  30. Dau,T., Bartolomucci,G. and Rappsilber,J.
    Proteomics Using Protease Alternatives to Trypsin Benefits from Sequential Digestion with Trypsin
    Anal Chem (2020) 92, 9523-9527. PubMed  Europe PubMed DOI  PMC  EPMC
  31. De Marco Verissimo,C., Jewhurst,H.L., Tikhonova,I.G., Urbanus,R.T., Maule,A.G., Dalton,J.P. and Cwiklinski,K.
    Fasciola hepatica serine protease inhibitor family (serpins): Purposely crafted for regulating host proteases
    PLoS Negl Trop Dis (2020) 14, e0008510-e0008510. PubMed  Europe PubMed DOI
  32. Di Giosia,M., Marforio,T.D., Cantelli,A., Valle,F., Zerbetto,F., Su,Q., Wang,H. and Calvaresi,M.
    Inhibition of alpha-chymotrypsin by pristine single-wall carbon nanotubes: clogging up the active site
    J Colloid Interface Sci (2020) 571, 174-184. PubMed  Europe PubMed DOI  I
  33. Gault,S., Jaworek,M.W., Winter,R. and Cockell,C.S.
    High pressures increase alpha-chymotrypsin enzyme activity under perchlorate stress
    Commun Biol (2020) 3, 550-550. PubMed  Europe PubMed DOI  PMC  EPMC
  34. Hasan,S., Isar,M. and Naeem,A.
    Macromolecular crowding stabilises native structure of alpha-chymotrypsinogen-A against hexafluoropropanol-induced aggregates
    Int J Biol Macromol (2020) PubMed  Europe PubMed DOI
  35. Li,G., Wei,H., Bi,J., Ding,X., Li,L., Xu,S., Yang,G. and Ren,W.
    Insights into dietary switch in cetaceans: evidence from molecular evolution of proteinases and lipases
    J Mol Evol (2020) PubMed  Europe PubMed DOI
  36. Mosztbacher,D., Demcsak,A. and Sahin-Toth,M.
    Measuring digestive protease activation in the mouse pancreas
    Pancreatology (2020) 20, 288-292. PubMed  Europe PubMed DOI  A
  37. Ostermeier,L., Oliva,R. and Winter,R.
    The multifaceted effects of DMSO and high hydrostatic pressure on the kinetic constants of hydrolysis reactions catalyzed by alpha-chymotrypsin
    Phys Chem Chem Phys (2020) 22, 16325-16333. PubMed  Europe PubMed DOI
  38. Yang,F., Totsingan,F., Dolan,E., Khare,S.D. and Gross,R.A.
    Protease-catalyzed l-aspartate oligomerization: substrate selectivity and computational modeling
    ACS Omega (2020) 5, 4403-4414. PubMed  Europe PubMed DOI  PMC  EPMC
    39. 2019
  39. Ramesh,B., Abnouf,S., Mali,S., Moree,W.J., Patil,U., Bark,S.J. and Varadarajan,N.
    Engineered chymotrypsiN for mass spectrometry-based detection of protein glycosylation
    ACS Chem Biol (2019) 14, 2616-2628. PubMed  Europe PubMed DOI  P
  40. Schumann,N.C., Bruning,J., Marshall,A.C. and Abell,A.D.
    The role of N-terminal heterocycles in hydrogen bonding to alpha-chymotrypsin
    Bioorg Med Chem Lett (2019) 29, 396-399. PubMed  Europe PubMed DOI  I
  41. Shi,Y.J., Huang,C.H., Lee,Y.C., Wang,L.J., Chiou,J.T. and Chang,L.S.
    Naja atra cardiotoxins enhance the protease activity of chymotrypsin
    Int J Biol Macromol (2019) 136, 512-520. PubMed  Europe PubMed DOI
    42. 2018
  42. Dusekova,E., Garajova,K., Yavaser,R., Varhac,R. and Sedlak,E.
    Hofmeister effect on catalytic properties of chymotrypsin is substrate-dependent
    Biophys Chem (2018) 243, 8-16. PubMed  Europe PubMed DOI
  43. Efremova,M.V., Veselov,M.M., Barulin,A.V., Gribanovsky,S.L., Le-Deygen,I.M., Uporov,I.V., Kudryashova,E.V., Sokolsky-Papkov,M., Majouga,A.G., Golovin,Y.I., Kabanov,A.V. and Klyachko,N.L.
    In situ observation of chymotrypsin catalytic activity change actuated by nonheating low-frequency magnetic field
    ACS Nano (2018) 12, 3190-3199. PubMed  Europe PubMed DOI
  44. Farhadian,S., Shareghi,B., Momeni,L., Abou-Zied,O.K., Sirotkin,V.A., Tachiya,M. and Saboury,A.A.
    Insights into the molecular interaction between sucrose and alpha-chymotrypsin
    Int J Biol Macromol (2018) 114, 950-960. PubMed  Europe PubMed DOI
  45. Luo,X., Zhu,W., Ding,L., Ye,X., Gao,H., Tai,X., Wu,Z., Qian,Y., Ruan,X., Li,J., Li,S. and Chen,Z.
    Bldesin, the first functionally characterized pathogenic fungus defensin with Kv1.3 channel and chymotrypsin inhibitory activities
    J Biochem Mol Toxicol (2018) , e22244-e22244. PubMed  Europe PubMed DOI  I
  46. Wang,J., Zheng,X., Wang,W., Guo,H., Liu,R. and Zong,W.
    A study on the interaction between cadmium and alpha-chymotrypsin and the underlying mechanisms
    J Biochem Mol Toxicol (2018) , e22248-e22248. PubMed  Europe PubMed DOI
  47. Yang,L., Li,H., Wu,P., Mahal,A., Xue,J., Xu,L. and Wei,X.
    Dinghupeptins A-D, chymotrypsin inhibitory cyclodepsipeptides produced by a soil-derived Streptomyces
    J Nat Prod (2018) 81, 1928-1936. PubMed  Europe PubMed DOI  I
    48. 2017
  48. Andersson,C.D., Martinez,N., Zeller,D., Rondahl,S.H., Koza,M.M., Frick,B., Ekstrom,F., Peters,J. and Linusson,A.
    Changes in dynamics of alpha-chymotrypsin due to covalent inhibitors investigated by elastic incoherent neutron scattering
    Phys Chem Chem Phys (2017) 19, 25369-25379. PubMed  Europe PubMed DOI  I
  49. Ghosh,C., Mondal,T. and Bhattacharyya,K.
    Enzyme activity of alpha-chymotrypsin: deactivation by gold nano-cluster and reactivation by glutathione
    J Colloid Interface Sci (2017) 494, 74-81. PubMed  Europe PubMed DOI  I
  50. Li,S., Fu,Y., Ma,X. and Zhang,Y.
    Label-free fluorometric detection of chymotrypsin activity using graphene oxide/nucleic-acid-stabilized silver nanoclusters hybrid materials
    Biosens Bioelectron (2017) 88, 210-216. PubMed  Europe PubMed DOI  A
  51. Marasini,B.P., Rahim,F., Perveen,S., Karim,A., Mohammed Khan,K., Atta-Ur-Rahman and Choudhary,M.I.
    Synthesis, structure-activity relationships studies of benzoxazinone derivatives as alpha-chymotrypsin inhibitors
    Bioorg Chem (2017) 70, 210-221. PubMed  Europe PubMed DOI  I
  52. Patra,A., Samanta,N., Das,D.K. and Mitra,R.K.
    Enhanced catalytic activity of alpha-chymotrypsin in cationic surfactant solutions: the component specificity revisited
    J Phys Chem B (2017) 121, 1457-1465. PubMed  Europe PubMed DOI
  53. Sirotkin,V.A. and Kuchierskaya,A.A.
    Preferential solvation/hydration of alpha-chymotrypsin in water-acetonitrile mixtures
    J Phys Chem B (2017) 121, 4422-4430. PubMed  Europe PubMed DOI
  54. Stewart,J.J.
    An investigation into the applicability of the semiempirical method PM7 for modeling the catalytic mechanism in the enzyme chymotrypsin
    J Mol Model (2017) 23, 154-154. PubMed  Europe PubMed DOI
  55. Stratton,A., Ericksen,M., Harris,T.V., Symmonds,N. and Silverstein,T.P.
    Mercury(II) binds to both of chymotrypsin's histidines, causing inhibition followed by irreversible denaturation/aggregation
    Protein Sci (2017) 26, 292-305. PubMed  Europe PubMed DOI  I
  56. Wu,L., Yang,S.H., Xiong,H., Yang,J.Q., Guo,J., Yang,W.C. and Yang,G.F.
    Nonpeptide-based small-molecule probe for fluorogenic and chromogenic detection of chymotrypsin
    Anal Chem (2017) 89, 3687-3693. PubMed  Europe PubMed DOI  A
  57. Zhang,S.-G., Xie,Z.-B., Liu,L.-S., Liang,M. and Le,Z.-G.
    Synthesis of 2,3-dihydroquinazolin-4(1H)-ones catalyzed by alpha-chymotrypsin
    Chin Chem Lett (2017) 28, 101-104. DOI
    58. 2016
  58. Bagchi,D., Ghosh,A., Singh,P., Dutta,S., Polley,N., Althagafi,I.I., Jassas,R.S., Ahmed,S.A. and Pal,S.K.
    Allosteric inhibitory molecular recognition of a photochromic dye by a digestive enzyme: dihydroindolizine makes alpha-chymotrypsin photo-responsive
    Sci Rep (2016) 6, 34399-34399. PubMed  Europe PubMed DOI
  59. Garringer,M. and Qasim,M.A.
    Effect of osmolytes and guanidinium chloride on the enzymatic properties of bovine alpha-chymotrypsin
    Protein Pept Lett (2016) 23, 504-507. PubMed  Europe PubMed
  60. Giansanti,P., Tsiatsiani,L., Low,T.Y. and Heck,A.J.
    Six alternative proteases for mass spectrometry-based proteomics beyond trypsin
    Nat Protoc (2016) 11, 993-1006. PubMed  Europe PubMed DOI
  61. Kanamori,Y., Iwasaki,A., Sumimoto,S. and Suenaga,K.
    Urumamide, a novel chymotrypsin inhibitor with a beta-amino acid from a marine cyanobacterium Okeania sp
    Tetrahedron Lett (2016) 57, 4213-4216. DOI  I
  62. Liang,M., Xie,Z., Ai,F. and Le,Z.
    Synthesis of quinoline derivatives catalyzed by alpha-chymotrypsin
    Chin J Org Chem (2016) 36, 2704-2708. DOI
  63. Ono,S., Nakai,T., Kuroda,H., Miyatake,R., Horino,Y., Abe,H., Umezaki,M. and Oyama,H.
    Site-selective chemical modification of chymotrypsin using peptidyl derivatives bearing optically active diphenyl 1-amino-2-phenylethylphosphonate: stereochemical effect of the diphenyl phosphonate moiety
    Biopolymers (2016) 106, 521-530. PubMed  Europe PubMed DOI  I
  64. Schuabb,V., Winter,R. and Czeslik,C.
    Improved activity of alpha-chymotrypsin on silica particles - a high-pressure stopped-flow study
    Biophys Chem (2016) 218, 1-6. PubMed  Europe PubMed DOI
  65. Siddiqui,H., Farooq,R., Marasini,B.P., Malik,R., Syed,N., Moin,S.T., Atta-Ur-Rahman and Choudhary,M.I.
    Synthesis and in vitro alpha-chymotrypsin inhibitory activity of 6-chlorobenzimidazole derivatives
    Bioorg Med Chem (2016) 24, 3387-3395. PubMed  Europe PubMed DOI  I
  66. Uritsky,N., Shokhen,M. and Albeck,A.
    Stepwise versus concerted mechanisms in general-base catalysis by serine proteases
    Angew Chem Int Ed Engl (2016) 55, 1680-1684. PubMed  Europe PubMed DOI
  67. Zhang,X., Bruning,J.B., George,J.H. and Abell,A.D.
    A mechanistic study on the inhibition of alpha-chymotrypsin by a macrocyclic peptidomimetic aldehyde
    Org Biomol Chem (2016) 14, 6970-6978. PubMed  Europe PubMed DOI  I
    68. 2015
  68. Kurinomaru,T., Kameda,T. and Shiraki,K.
    Effects of multivalency and hydrophobicity of polyamines on enzyme hyperactivation of alpha-chymotrypsin
    J Mol Catal B Enzym (2015) 115, 135-139. DOI
  69. Li,L.-P., Cai,X., Xiang,Y., Zhang,Y., Song,J., Yang,D.-C., Guan,Z. and He,Y.-H.
    The alpha-chymotrypsin-catalyzed Povarov reaction: one-pot synthesis of tetrahydroquinoline derivatives
    Green Chem (2015) 17, 3148-3156. DOI
  70. Luong,T.Q. and Winter,R.
    Combined pressure and cosolvent effects on enzyme activity - a high-pressure stopped-flow kinetic study on alpha-chymotrypsin
    Phys Chem Chem Phys (2015) 17, 23273-23278. PubMed  Europe PubMed DOI
  71. Romero,C.M., Abella,J.S., Velazquez,A. and Sancho,J.
    Thermal denaturation of alpha-chymotrypsinogen A in presence of polyols at pH 2.0 and pH 3.0
    J Therm Anal Calor (2015) 120, 489-499. DOI
  72. Shibao,P.Y., Anjolette,F.A., Lopes,N.P. and Arantes,E.C.
    First serine protease inhibitor isolated from Rhinella schneideri poison
    J Venom Anim Toxins Incl Trop Dis (2015) 21, 30-30. PubMed  Europe PubMed DOI  PMC  EPMC  I
  73. Sun,D., Jiang,G., Xie,Z. and Le,Z.
    alpha-chymotrypsin-catalyzed synthesis of bis(indolyl)alkanes in water
    Chin J Chem (2015) 33, 409-412. DOI
  74. Uccello-Barretta,G., Balzano,F., Aiello,F., Vanni,L., Mori,M., Menta,S., Calcaterra,A. and Botta,B.
    Hydrolytic inhibition of alpha-chymotrypsin by 2,8,14,20-tetrakis(d-leucyl-d-valinamido)resorc[4]arenecarboxylic acid: a spectroscopic NMR and computational combined approach
    Org Biomol Chem (2015) 13, 916-924. PubMed  Europe PubMed DOI  I
  75. Zhang,L., Xiao,X., Yuan,Y., Guo,Y., Li,M. and Pu,X.
    Probing immobilization mechanism of alpha-chymotrypsin onto carbon nanotube in organic media by molecular dynamics simulation
    Sci Rep (2015) 5, 9297-9297. PubMed  Europe PubMed DOI
  76. Zhang,X., Heng,S. and Abell,A.D.
    Photoregulation of alpha-chymotrypsin activity by spiropyran-based inhibitors in solution and attached to an optical fiber
    Chemistry (2015) 21, 10703-10713. PubMed  Europe PubMed DOI  I
    77. 2014
  77. Chen,Q., Zhang,J., Zhao,K., Li,W., Miao,Q., Sun,Y., Zhao,X., Wei,T. and Yang,F.
    Lysosomal chymotrypsin induces mitochondrial fission in apoptotic cells by proteolytic activation of calcineurin
    Protein Cell (2014) 5, 643-647. PubMed  Europe PubMed DOI
  78. Cleary,J.A., Doherty,W., Evans,P. and Malthouse,J.P.
    Hemiacetal stabilization in a chymotrypsin inhibitor complex and the reactivity of the hydroxyl group of the catalytic serine residue of chymotrypsin
    Biochim Biophys Acta (2014) 1844, 1119-1127. PubMed  Europe PubMed DOI  I
  79. Gupta,B.S., Taha,M. and Lee,M.-J.
    Superactivity of alpha-chymotrypsin with biological buffers, TRIS, TES, TAPS, and TAPSO in aqueous solutions
    RSC Adv (2014) 4, 51111-51116. DOI
  80. Khan,Z.A., Afzal,N., Hussain,Z., Naqvi,S.A.R., Bari,A., Shahzad,S.A., Yar,M., Mahmood,N., Bukhari,S.A., Mansha,A., Zahoor,A.F., Khan,A.R. and Ahmad,M.
    Synthesis of 2-aryl-4H-3,1-benzoxazin-4-ones: a class of alpha-chymotrypsin inhibitors
    Asian J Chem (2014) 26, 4561-4565. DOI  I
  81. Latif,M.A., Tejo,B.A., Abedikargiban,R., Abdul Rahman,M.B. and Micaelo,N.M.
    Modeling stability and flexibility of alpha-chymotrypsin in room temperature ionic liquids
    J Biomol Struct Dyn (2014) 32, 1263-1273. PubMed  Europe PubMed DOI
  82. Murata,H., Cummings,C.S., Koepsel,R.R. and Russell,A.J.
    Rational tailoring of substrate and inhibitor affinity via ATRP polymer-based protein engineering
    Biomacromolecules (2014) 15, 2817-2823. PubMed  Europe PubMed DOI
  83. Perveen,S., Mustafa,S., Latif,M., Iqbal,L., Usmani,T.H., Khan,K.M. and Voelter,W.
    Unsymmetrical 1,3-disubstituted urea derivatives as alpha-chymotrypsin inhibitors
    Med Chem Res (2014) 23, 3585-3592. DOI  I
  84. Xie,Z.B., Sun,D.Z., Jiang,G.F. and Le,Z.G.
    Facile synthesis of bis(indolyl)methanes catalyzed by alpha-chymotrypsin
    Molecules (2014) 19, 19665-19677. PubMed  Europe PubMed DOI
    85. 2013
  85. Karna,N., Debowski,D., Gitlin,A., Legowska,A. and Rolka,K.
    Investigation of peptide splicing using two-peptide-chain analogs of trypsin inhibitor SFTI-1
    FEBS J (2013) 280, 6213-6222. PubMed  Europe PubMed DOI
  86. Moyano,F., Setien,E., Silber,J.J. and Correa,N.M.
    Enzymatic hydrolysis of N-benzoyl-L-tyrosine p-nitroanilide by alpha-chymotrypsin in DMSO-water/AOT/n-heptane reverse micelles. A unique interfacial effect on the enzymatic activity
    Langmuir (2013) 29, 8245-8254. PubMed  Europe PubMed DOI
  87. Terentyeva,T.G., Hofkens,J., Komatsuzaki,T., Blank,K. and Li,C.B.
    Time-resolved single molecule fluorescence spectroscopy of an alpha-chymotrypsin catalyzed reaction
    J Phys Chem B (2013) 117, 1252-1260. PubMed  Europe PubMed DOI
  88. Vorob'ev,M.M.
    Quantification of two-step proteolysis model with consecutive demasking and hydrolysis of peptide bonds using casein hydrolysis by chymotrypsin
    Biochem Eng J (2013) 74, 60-68.
  89. Yamashita,S., Sakabe,M., Ishizawa,T., Hasegawa,K., Urano,Y. and Kokudo,N.
    Visualization of the leakage of pancreatic juice using a chymotrypsin-activated fluorescent probe
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