Literature for peptidase S01.001: chymotrypsin A (cattle-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, P Specificity, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Stefan,A. and Hochkoeppler,A.
    The catalytic action of enzymes exposed to charged substrates outperforms the activity exerted on their neutral counterparts
    Biochem Biophys Res Commun751, 151436-151436. PubMed  Europe PubMed DOI
  2. 2024
  3. Ansari,N.K., Khan,H.S. and Naeem,A.
    Doxorubicin as a Drug Repurposing for Disruption of alpha-Chymotrypsinogen-A Aggregates
    Protein J43, 842-857. PubMed  Europe PubMed DOI
  4. Gajardo-Parra,N.F., Cea-Klapp,E., Chandra,A., Canales,R., Garrido,J.M., Held,C. and Guajardo,N.V.
    Assessing the effect of deep eutectic solvents on alpha-chymotrypsin thermal stability and activity
    ChemSusCheme202401414-e202401414. PubMed  Europe PubMed DOI
  5. Gholizadeh,M., Shareghi,B. and Farhadian,S.
    Revealing the interaction between alpha-chymotrypsin and eugenol: An integrated multi-spectral and dynamic simulation approach
    Int J Biol Macromol277, 134504-134504. PubMed  Europe PubMed DOI
  6. Patel,C.K. and Mukherjee,T.K.
    Biomolecular Condensation of Trypsin Prevents Autolysis and Promotes Ca(2+)-Mediated Activation of Esterase Activity
    Biomacromolecules25, 6082-6092. PubMed  Europe PubMed DOI
  7. Shirazi,S.H., Rizvi,F., Sherwani,Z.A., Siddiqui,A.R., Ul-Haq,Z., Siddiqui,H., Choudhary,M.I. and Ahmad,M.S.
    Synthesis of isoniazid derivatives and evaluation of their alpha-chymotrypsin inhibitory effect through in silico guided in vitro studies
    Biochem Biophys Res Commun735, 150805-150805. PubMed  Europe PubMed DOI  I
  8. Sindhikara,D., Iskandar,S.E., Guan,L., Maini,R., Hipolito,C.J., Sun,C., Vasicek,L.A., Weinglass,A. and Saldanha,S.A.
    Analysis and Prediction of Chymotrypsin Substrate Preferences through Large Data Acquisition with Target-Free mRNA Display
    Chembiocheme202400760-e202400760. PubMed  Europe PubMed DOI
  9. Yadav,B., Yadav,N. and Venkatesu,P.
    Unravelling the stabilization mechanism of mono-, di- and tri-cholinium citrate-ethylene glycol DESs towards alpha-chymotrypsin for preservation and activation of the enzyme
    Phys Chem Chem Phys26, 28025-28036. PubMed  Europe PubMed DOI
  10. Ying,Y. and Li,H.
    Native top-down mass spectrometry for monitoring the rapid chymotrypsin catalyzed hydrolysis reaction
    Anal Chim Acta1285, 341971-341971. PubMed  Europe PubMed DOI
  11. 2023
  12. Solovyev,M., Kashinskaya,E. and Gisbert,E.
    A meta-analysis for assessing the contributions of trypsin and chymotrypsin as the two major endoproteases in protein hydrolysis in fish intestine
    Comp Biochem Physiol A Mol Integr Physiol278, 111372-111372. PubMed  Europe PubMed DOI
  13. Vreeke,G.J.C., Vincken,J.P. and Wierenga,P.A.
    The path of proteolysis by bovine chymotrypsin
    Food Res Int165, 112485-112485. PubMed  Europe PubMed DOI
  14. 2022
  15. Balabushevich,N.G., Kovalenko,E.A., Filatova,L.Y., Kirzhanova,E.A., Mikhalchik,E.V., Volodkin,D. and Vikulina,A.S.
    Hybrid Mucin-Vaterite Microspheres for Delivery of Proteolytic Enzyme Chymotrypsin
    Macromol Biosci22, e2200005-e2200005. PubMed  Europe PubMed DOI
  16. Biswas,P., Adhikari,A., Pal,U., Mondal,S., Mukherjee,D., Ghosh,R., Obaid,R.J., Moussa,Z., Choudhury,S.S., Ahmed,S.A., Das,R. and Pal,S.K.
    A combined spectroscopic and molecular modeling Study on structure-function-dynamics under chemical modification: Alpha-chymotrypsin with formalin preservative
    Front Chem10, 978668-978668. PubMed  Europe PubMed DOI
  17. Gul,S. and Khan,A.M.
    Molecular docking studies of isolated marine natural products against alpha-chymotrypsin
    Nat Prod Res1-4. PubMed  Europe PubMed DOI
  18. Lan,T., Tian,Q.Q., Li,M.H. and He,W.
    Activatable endoplasmic reticulum-targeted NIR fluorescent probe with a large Stokes shift for detecting and imaging chymotrypsin
    Analyst147, 4098-4104. PubMed  Europe PubMed DOI
  19. Liu,K.
    Method development and optimization for measuring chymotrypsin and chymotrypsin inhibitor activities
    J Food Sci87, 2018-2033. PubMed  Europe PubMed DOI
  20. Liu,S.Y., Zou,X., Gao,X. and Zhang,Y.Y.
    De Novo Design of a Highly Selective Nonpeptide Fluorogenic Probe for Chymotrypsin Activity Sensing in a Living System
    Anal Chem94, 17922-17929. PubMed  Europe PubMed DOI
  21. Nemeth,B.Z., Demcsak,A., Micsonai,A., Kiss,B., Schlosser,G., Geisz,A., Hegyi,E., Sahin-Toth,M. and Pal,G.
    Arg236 in human chymotrypsin B2 (CTRB2) is a key determinant of high enzyme activity, trypsinogen degradation capacity, and protection against pancreatitis
    Biochim Biophys Acta Proteins Proteom1870, 140831-140831. PubMed  Europe PubMed DOI
  22. Riley,M.B., Strandquist,E., Weitzel,C.S. and Driskell,J.D.
    Structure and activity of native and thiolated alpha-chymotrypsin adsorbed onto gold nanoparticles
    Colloids Surf B Biointerfaces220, 112867-112867. PubMed  Europe PubMed DOI
  23. Song,Y., Gong,K., Yan,H., Hong,W., Wang,L., Wu,Y., Li,W., Li,W. and Cao,Z.
    Correction: Sj7170, a unique dual-function peptide with a specific alpha-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom
    J Biol Chem298, 102543-102543. PubMed  Europe PubMed DOI
  24. 2021
  25. Fu,Z., Akula,S., Thorpe,M. and Hellman,L.
    Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins
    Biol Chem402, 861-867. PubMed  Europe PubMed DOI
  26. Gault,S. and Cockell,C.S.
    Perchlorate Salts Exert a Dominant, Deleterious Effect on the Structure, Stability, and Activity of alpha-Chymotrypsin
    Astrobiology21, 405-412. PubMed  Europe PubMed DOI
  27. Gault,S., Jaworek,M.W., Winter,R. and Cockell,C.S.
    Perchlorate salts confer psychrophilic characteristics in alpha-chymotrypsin
    Sci Rep11, 16523-16523. PubMed  Europe PubMed DOI
  28. Lather,J. and George,J.
    Improving Enzyme Catalytic Efficiency by Co-operative Vibrational Strong Coupling of Water
    J Phys Chem Lett12, 379-384. PubMed  Europe PubMed DOI
  29. Li,H., Wang,Y., He,X., Chen,J., Xu,F., Liu,Z. and Zhou,Y.
    A green deep eutectic solvent modified magnetic titanium dioxide nanoparticles for the solid-phase extraction of chymotrypsin
    Talanta230, 122341-122341. PubMed  Europe PubMed DOI
  30. Mahmoud,G.S., Hosny,G. and Sayed,S.A.
    Hepatoprotective effect of trypsin/chymotrypsin against olanzapine-induced non-alcoholic steatohepatitis in rats
    Can J Physiol Pharmacol1-9. PubMed  Europe PubMed DOI
  31. Piovarci,I., Hianik,T. and Ivanov,I.N.
    Detection of Chymotrypsin by Optical and Acoustic Methods
    Biosensors (Basel)11, PubMed  Europe PubMed DOI
  32. Zou,X., Zhao,Y., Lai,C., Liang,Y. and Lin,W.
    A non-peptide probe for detecting chymotrypsin activity based on protection-deprotection strategy in living systems
    J Mater Chem B9, 8417-8423. PubMed  Europe PubMed DOI
  33. 2020
  34. Dau,T., Bartolomucci,G. and Rappsilber,J.
    Proteomics Using Protease Alternatives to Trypsin Benefits from Sequential Digestion with Trypsin
    Anal Chem92, 9523-9527. PubMed  Europe PubMed DOI
  35. De Marco Verissimo,C., Jewhurst,H.L., Tikhonova,I.G., Urbanus,R.T., Maule,A.G., Dalton,J.P. and Cwiklinski,K.
    Fasciola hepatica serine protease inhibitor family (serpins): Purposely crafted for regulating host proteases
    PLoS Negl Trop Dis14, e0008510-e0008510. PubMed  Europe PubMed DOI
  36. Di Giosia,M., Marforio,T.D., Cantelli,A., Valle,F., Zerbetto,F., Su,Q., Wang,H. and Calvaresi,M.
    Inhibition of alpha-chymotrypsin by pristine single-wall carbon nanotubes: clogging up the active site
    J Colloid Interface Sci571, 174-184. PubMed  Europe PubMed DOI  I
  37. Gault,S., Jaworek,M.W., Winter,R. and Cockell,C.S.
    High pressures increase alpha-chymotrypsin enzyme activity under perchlorate stress
    Commun Biol3, 550-550. PubMed  Europe PubMed DOI
  38. Hasan,S., Isar,M. and Naeem,A.
    Macromolecular crowding stabilises native structure of alpha-chymotrypsinogen-A against hexafluoropropanol-induced aggregates
    Int J Biol Macromol PubMed  Europe PubMed DOI
  39. Li,G., Wei,H., Bi,J., Ding,X., Li,L., Xu,S., Yang,G. and Ren,W.
    Insights into dietary switch in cetaceans: evidence from molecular evolution of proteinases and lipases
    J Mol Evol PubMed  Europe PubMed DOI
  40. Mosztbacher,D., Demcsak,A. and Sahin-Toth,M.
    Measuring digestive protease activation in the mouse pancreas
    Pancreatology20, 288-292. PubMed  Europe PubMed DOI  A
  41. Ostermeier,L., Oliva,R. and Winter,R.
    The multifaceted effects of DMSO and high hydrostatic pressure on the kinetic constants of hydrolysis reactions catalyzed by alpha-chymotrypsin
    Phys Chem Chem Phys22, 16325-16333. PubMed  Europe PubMed DOI
  42. Yang,F., Totsingan,F., Dolan,E., Khare,S.D. and Gross,R.A.
    Protease-catalyzed l-aspartate oligomerization: substrate selectivity and computational modeling
    ACS Omega5, 4403-4414. PubMed  Europe PubMed DOI
  43. 2019
  44. Ramesh,B., Abnouf,S., Mali,S., Moree,W.J., Patil,U., Bark,S.J. and Varadarajan,N.
    Engineered chymotrypsiN for mass spectrometry-based detection of protein glycosylation
    ACS Chem Biol14, 2616-2628. PubMed  Europe PubMed DOI  P
  45. Schumann,N.C., Bruning,J., Marshall,A.C. and Abell,A.D.
    The role of N-terminal heterocycles in hydrogen bonding to alpha-chymotrypsin
    Bioorg Med Chem Lett29, 396-399. PubMed  Europe PubMed DOI  I
  46. Shi,Y.J., Huang,C.H., Lee,Y.C., Wang,L.J., Chiou,J.T. and Chang,L.S.
    Naja atra cardiotoxins enhance the protease activity of chymotrypsin
    Int J Biol Macromol136, 512-520. PubMed  Europe PubMed DOI
  47. 2018
  48. Dusekova,E., Garajova,K., Yavaser,R., Varhac,R. and Sedlak,E.
    Hofmeister effect on catalytic properties of chymotrypsin is substrate-dependent
    Biophys Chem243, 8-16. PubMed  Europe PubMed DOI
  49. Efremova,M.V., Veselov,M.M., Barulin,A.V., Gribanovsky,S.L., Le-Deygen,I.M., Uporov,I.V., Kudryashova,E.V., Sokolsky-Papkov,M., Majouga,A.G., Golovin,Y.I., Kabanov,A.V. and Klyachko,N.L.
    In situ observation of chymotrypsin catalytic activity change actuated by nonheating low-frequency magnetic field
    ACS Nano12, 3190-3199. PubMed  Europe PubMed DOI
  50. Farhadian,S., Shareghi,B., Momeni,L., Abou-Zied,O.K., Sirotkin,V.A., Tachiya,M. and Saboury,A.A.
    Insights into the molecular interaction between sucrose and alpha-chymotrypsin
    Int J Biol Macromol114, 950-960. PubMed  Europe PubMed DOI
  51. Luo,X., Zhu,W., Ding,L., Ye,X., Gao,H., Tai,X., Wu,Z., Qian,Y., Ruan,X., Li,J., Li,S. and Chen,Z.
    Bldesin, the first functionally characterized pathogenic fungus defensin with Kv1.3 channel and chymotrypsin inhibitory activities
    J Biochem Mol Toxicole22244-e22244. PubMed  Europe PubMed DOI  I
  52. Wang,J., Zheng,X., Wang,W., Guo,H., Liu,R. and Zong,W.
    A study on the interaction between cadmium and alpha-chymotrypsin and the underlying mechanisms
    J Biochem Mol Toxicole22248-e22248. PubMed  Europe PubMed DOI
  53. Yang,L., Li,H., Wu,P., Mahal,A., Xue,J., Xu,L. and Wei,X.
    Dinghupeptins A-D, chymotrypsin inhibitory cyclodepsipeptides produced by a soil-derived Streptomyces
    J Nat Prod81, 1928-1936. PubMed  Europe PubMed DOI  I
  54. 2017
  55. Andersson,C.D., Martinez,N., Zeller,D., Rondahl,S.H., Koza,M.M., Frick,B., Ekstrom,F., Peters,J. and Linusson,A.
    Changes in dynamics of alpha-chymotrypsin due to covalent inhibitors investigated by elastic incoherent neutron scattering
    Phys Chem Chem Phys19, 25369-25379. PubMed  Europe PubMed DOI  I
  56. Ghosh,C., Mondal,T. and Bhattacharyya,K.
    Enzyme activity of alpha-chymotrypsin: deactivation by gold nano-cluster and reactivation by glutathione
    J Colloid Interface Sci494, 74-81. PubMed  Europe PubMed DOI  I
  57. Li,S., Fu,Y., Ma,X. and Zhang,Y.
    Label-free fluorometric detection of chymotrypsin activity using graphene oxide/nucleic-acid-stabilized silver nanoclusters hybrid materials
    Biosens Bioelectron88, 210-216. PubMed  Europe PubMed DOI  A
  58. Marasini,B.P., Rahim,F., Perveen,S., Karim,A., Mohammed Khan,K., Atta-Ur-Rahman and Choudhary,M.I.
    Synthesis, structure-activity relationships studies of benzoxazinone derivatives as alpha-chymotrypsin inhibitors
    Bioorg Chem70, 210-221. PubMed  Europe PubMed DOI  I
  59. Patra,A., Samanta,N., Das,D.K. and Mitra,R.K.
    Enhanced catalytic activity of alpha-chymotrypsin in cationic surfactant solutions: the component specificity revisited
    J Phys Chem B121, 1457-1465. PubMed  Europe PubMed DOI
  60. Sirotkin,V.A. and Kuchierskaya,A.A.
    Preferential solvation/hydration of alpha-chymotrypsin in water-acetonitrile mixtures
    J Phys Chem B121, 4422-4430. PubMed  Europe PubMed DOI
  61. Stewart,J.J.
    An investigation into the applicability of the semiempirical method PM7 for modeling the catalytic mechanism in the enzyme chymotrypsin
    J Mol Model23, 154-154. PubMed  Europe PubMed DOI
  62. Stratton,A., Ericksen,M., Harris,T.V., Symmonds,N. and Silverstein,T.P.
    Mercury(II) binds to both of chymotrypsin's histidines, causing inhibition followed by irreversible denaturation/aggregation
    Protein Sci26, 292-305. PubMed  Europe PubMed DOI  I
  63. Wu,L., Yang,S.H., Xiong,H., Yang,J.Q., Guo,J., Yang,W.C. and Yang,G.F.
    Nonpeptide-based small-molecule probe for fluorogenic and chromogenic detection of chymotrypsin
    Anal Chem89, 3687-3693. PubMed  Europe PubMed DOI  A
  64. Zhang,S.-G., Xie,Z.-B., Liu,L.-S., Liang,M. and Le,Z.-G.
    Synthesis of 2,3-dihydroquinazolin-4(1H)-ones catalyzed by alpha-chymotrypsin
    Chin Chem Lett28, 101-104. DOI
  65. 2016
  66. Bagchi,D., Ghosh,A., Singh,P., Dutta,S., Polley,N., Althagafi,I.I., Jassas,R.S., Ahmed,S.A. and Pal,S.K.
    Allosteric inhibitory molecular recognition of a photochromic dye by a digestive enzyme: dihydroindolizine makes alpha-chymotrypsin photo-responsive
    Sci Rep6, 34399-34399. PubMed  Europe PubMed DOI
  67. Garringer,M. and Qasim,M.A.
    Effect of osmolytes and guanidinium chloride on the enzymatic properties of bovine alpha-chymotrypsin
    Protein Pept Lett23, 504-507. PubMed  Europe PubMed
  68. Giansanti,P., Tsiatsiani,L., Low,T.Y. and Heck,A.J.
    Six alternative proteases for mass spectrometry-based proteomics beyond trypsin
    Nat Protoc11, 993-1006. PubMed  Europe PubMed DOI
  69. Kanamori,Y., Iwasaki,A., Sumimoto,S. and Suenaga,K.
    Urumamide, a novel chymotrypsin inhibitor with a beta-amino acid from a marine cyanobacterium Okeania sp
    Tetrahedron Lett57, 4213-4216. DOI  I
  70. Liang,M., Xie,Z., Ai,F. and Le,Z.
    Synthesis of quinoline derivatives catalyzed by alpha-chymotrypsin
    Chin J Org Chem36, 2704-2708. DOI
  71. Ono,S., Nakai,T., Kuroda,H., Miyatake,R., Horino,Y., Abe,H., Umezaki,M. and Oyama,H.
    Site-selective chemical modification of chymotrypsin using peptidyl derivatives bearing optically active diphenyl 1-amino-2-phenylethylphosphonate: stereochemical effect of the diphenyl phosphonate moiety
    Biopolymers106, 521-530. PubMed  Europe PubMed DOI  I
  72. Schuabb,V., Winter,R. and Czeslik,C.
    Improved activity of alpha-chymotrypsin on silica particles - a high-pressure stopped-flow study
    Biophys Chem218, 1-6. PubMed  Europe PubMed DOI
  73. Siddiqui,H., Farooq,R., Marasini,B.P., Malik,R., Syed,N., Moin,S.T., Atta-Ur-Rahman and Choudhary,M.I.
    Synthesis and in vitro alpha-chymotrypsin inhibitory activity of 6-chlorobenzimidazole derivatives
    Bioorg Med Chem24, 3387-3395. PubMed  Europe PubMed DOI  I
  74. Uritsky,N., Shokhen,M. and Albeck,A.
    Stepwise versus concerted mechanisms in general-base catalysis by serine proteases
    Angew Chem Int Ed Engl55, 1680-1684. PubMed  Europe PubMed DOI
  75. Zhang,X., Bruning,J.B., George,J.H. and Abell,A.D.
    A mechanistic study on the inhibition of alpha-chymotrypsin by a macrocyclic peptidomimetic aldehyde
    Org Biomol Chem14, 6970-6978. PubMed  Europe PubMed DOI  I
  76. 2015
  77. Kurinomaru,T., Kameda,T. and Shiraki,K.
    Effects of multivalency and hydrophobicity of polyamines on enzyme hyperactivation of alpha-chymotrypsin
    J Mol Catal B Enzym115, 135-139. DOI
  78. Li,L.-P., Cai,X., Xiang,Y., Zhang,Y., Song,J., Yang,D.-C., Guan,Z. and He,Y.-H.
    The alpha-chymotrypsin-catalyzed Povarov reaction: one-pot synthesis of tetrahydroquinoline derivatives
    Green Chem17, 3148-3156. DOI
  79. Luong,T.Q. and Winter,R.
    Combined pressure and cosolvent effects on enzyme activity - a high-pressure stopped-flow kinetic study on alpha-chymotrypsin
    Phys Chem Chem Phys17, 23273-23278. PubMed  Europe PubMed DOI
  80. Romero,C.M., Abella,J.S., Velazquez,A. and Sancho,J.
    Thermal denaturation of alpha-chymotrypsinogen A in presence of polyols at pH 2.0 and pH 3.0
    J Therm Anal Calor120, 489-499. DOI
  81. Shibao,P.Y., Anjolette,F.A., Lopes,N.P. and Arantes,E.C.
    First serine protease inhibitor isolated from Rhinella schneideri poison
    J Venom Anim Toxins Incl Trop Dis21, 30-30. PubMed  Europe PubMed DOI  I
  82. Sun,D., Jiang,G., Xie,Z. and Le,Z.
    alpha-chymotrypsin-catalyzed synthesis of bis(indolyl)alkanes in water
    Chin J Chem33, 409-412. DOI
  83. Uccello-Barretta,G., Balzano,F., Aiello,F., Vanni,L., Mori,M., Menta,S., Calcaterra,A. and Botta,B.
    Hydrolytic inhibition of alpha-chymotrypsin by 2,8,14,20-tetrakis(d-leucyl-d-valinamido)resorc[4]arenecarboxylic acid: a spectroscopic NMR and computational combined approach
    Org Biomol Chem13, 916-924. PubMed  Europe PubMed DOI  I
  84. Zhang,L., Xiao,X., Yuan,Y., Guo,Y., Li,M. and Pu,X.
    Probing immobilization mechanism of alpha-chymotrypsin onto carbon nanotube in organic media by molecular dynamics simulation
    Sci Rep5, 9297-9297. PubMed  Europe PubMed DOI
  85. Zhang,X., Heng,S. and Abell,A.D.
    Photoregulation of alpha-chymotrypsin activity by spiropyran-based inhibitors in solution and attached to an optical fiber
    Chemistry21, 10703-10713. PubMed  Europe PubMed DOI  I
  86. 2014
  87. Chen,Q., Zhang,J., Zhao,K., Li,W., Miao,Q., Sun,Y., Zhao,X., Wei,T. and Yang,F.
    Lysosomal chymotrypsin induces mitochondrial fission in apoptotic cells by proteolytic activation of calcineurin
    Protein Cell5, 643-647. PubMed  Europe PubMed DOI
  88. Cleary,J.A., Doherty,W., Evans,P. and Malthouse,J.P.
    Hemiacetal stabilization in a chymotrypsin inhibitor complex and the reactivity of the hydroxyl group of the catalytic serine residue of chymotrypsin
    Biochim Biophys Acta1844, 1119-1127. PubMed  Europe PubMed DOI  I
  89. Gupta,B.S., Taha,M. and Lee,M.-J.
    Superactivity of alpha-chymotrypsin with biological buffers, TRIS, TES, TAPS, and TAPSO in aqueous solutions
    RSC Adv4, 51111-51116. DOI
  90. Khan,Z.A., Afzal,N., Hussain,Z., Naqvi,S.A.R., Bari,A., Shahzad,S.A., Yar,M., Mahmood,N., Bukhari,S.A., Mansha,A., Zahoor,A.F., Khan,A.R. and Ahmad,M.
    Synthesis of 2-aryl-4H-3,1-benzoxazin-4-ones: a class of alpha-chymotrypsin inhibitors
    Asian J Chem26, 4561-4565. DOI  I
  91. Latif,M.A., Tejo,B.A., Abedikargiban,R., Abdul Rahman,M.B. and Micaelo,N.M.
    Modeling stability and flexibility of alpha-chymotrypsin in room temperature ionic liquids
    J Biomol Struct Dyn32, 1263-1273. PubMed  Europe PubMed DOI
  92. Murata,H., Cummings,C.S., Koepsel,R.R. and Russell,A.J.
    Rational tailoring of substrate and inhibitor affinity via ATRP polymer-based protein engineering
    Biomacromolecules15, 2817-2823. PubMed  Europe PubMed DOI
  93. Perveen,S., Mustafa,S., Latif,M., Iqbal,L., Usmani,T.H., Khan,K.M. and Voelter,W.
    Unsymmetrical 1,3-disubstituted urea derivatives as alpha-chymotrypsin inhibitors
    Med Chem Res23, 3585-3592. DOI  I
  94. Xie,Z.B., Sun,D.Z., Jiang,G.F. and Le,Z.G.
    Facile synthesis of bis(indolyl)methanes catalyzed by alpha-chymotrypsin
    Molecules19, 19665-19677. PubMed  Europe PubMed DOI
  95. 2013
  96. Karna,N., Debowski,D., Gitlin,A., Legowska,A. and Rolka,K.
    Investigation of peptide splicing using two-peptide-chain analogs of trypsin inhibitor SFTI-1
    FEBS J280, 6213-6222. PubMed  Europe PubMed DOI
  97. Moyano,F., Setien,E., Silber,J.J. and Correa,N.M.
    Enzymatic hydrolysis of N-benzoyl-L-tyrosine p-nitroanilide by alpha-chymotrypsin in DMSO-water/AOT/n-heptane reverse micelles. A unique interfacial effect on the enzymatic activity
    Langmuir29, 8245-8254. PubMed  Europe PubMed DOI
  98. Terentyeva,T.G., Hofkens,J., Komatsuzaki,T., Blank,K. and Li,C.B.
    Time-resolved single molecule fluorescence spectroscopy of an alpha-chymotrypsin catalyzed reaction
    J Phys Chem B117, 1252-1260. PubMed  Europe PubMed DOI
  99. Vorob'ev,M.M.
    Quantification of two-step proteolysis model with consecutive demasking and hydrolysis of peptide bonds using casein hydrolysis by chymotrypsin
    Biochem Eng J74, 60-68.
  100. Yamashita,S., Sakabe,M., Ishizawa,T., Hasegawa,K., Urano,Y. and Kokudo,N.
    Visualization of the leakage of pancreatic juice using a chymotrypsin-activated fluorescent probe
    Br J Surg100, 1220-1228. PubMed  Europe PubMed DOI  A
  101. 2012
  102. Graf,L., Szilagyi,L. and Venekei,I.
    Chymotrypsin
    [ISSN:978-0-12-407742-3]3, 2626-2633. DOI
  103. Haerteis,S., Krappitz,M., Diakov,A., Krappitz,A., Rauh,R. and Korbmacher,C.
    Plasmin and chymotrypsin have distinct preferences for channel activating cleavage sites in the gamma subunit of the human epithelial sodium channel
    J Gen Physiol140, 375-389. PubMed  Europe PubMed DOI  P
  104. Hu,S.H., Kuo,C.H., Chang,C.M., Liu,Y.C., Chiang,W.D. and Shieh,C.J.
    Solvent selection and optimization of alpha-chymotrypsin-catalyzed synthesis of N-Ac-Phe-Tyr-NH2 using mixture design and response surface methodology
    Biotechnol Prog28, 1443-1449. PubMed  Europe PubMed DOI
  105. Liuni,P., Jeganathan,A. and Wilson,D.J.
    Conformer selection and intensified dynamics during catalytic turnover in chymotrypsin
    Angew Chem Int Ed Engl51, 9666-9669. PubMed  Europe PubMed DOI
  106. Petrillo,T., O'Donohoe,C.A., Howe,N. and Malthouse,J.P.
    Importance of tetrahedral intermediate formation in the catalytic mechanism of the serine proteases chymotrypsin and subtilisin
    Biochemistry51, 6164-6170. PubMed  Europe PubMed DOI  I
  107. Simon,L.M., Laczko,I., Demcsak,A., Toth,D., Kotorman,M. and Fulop,L.
    The formation of amyloid-like fibrils of alpha-chymotrypsin in different aqueous organic solvents
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