Literature for subfamily P2A

(Topics flags: S Structure, M Mutation, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2023
1. Fu,C., Huang,W., Tang,Q., Niu,M., Guo,S., Langenhan,T., Song,G. and Yan,J.
   Unveiling Mechanical Activation: GAIN Domain Unfolding and Dissociation in Adhesion GPCRs
   Nano Lett23, 9179-9186. PubMed  Europe PubMed DOI
2. Scholz,N., Dahse,A.K., Kemkemer,M., Bormann,A., Auger,G.M., Vieira Contreras,F., Ernst,L.F., Staake,H., Korner,M.B., Buhlan,M., Meyer-Molck,A., Chung,Y.K., Blanco-Redondo,B., Klose,F., Jarboui,M.A., Ljaschenko,D., Bigl,M. and Langenhan,T.
   Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation
   Nature615, 945-953. PubMed  Europe PubMed DOI
3. Seufert,F., Chung,Y.K., Hildebrand,P.W. and Langenhan,T.
   7TM domain structures of adhesion GPCRs: what's new and what's missing?
   Trends Biochem Sci48, 726-739. PubMed  Europe PubMed DOI  V
4. Thor,D. and Liebscher,I.
   Adhesion G protein-coupled receptors-Structure and functions
   Prog Mol Biol Transl Sci195, 1-25. PubMed  Europe PubMed DOI
2022
5. Barros-Alvarez,X., Nwokonko,R.M., Vizurraga,A., Matzov,D., He,F., Papasergi-Scott,M.M., Robertson,M.J., Panova,O., Yardeni,E.H., Seven,A.B., Kwarcinski,F.E., Su,H., Peroto,M.C., Meyerowitz,J.G., Shalev-Benami,M., Tall,G.G. and Skiniotis,G.
   The tethered peptide activation mechanism of adhesion GPCRs
   Nature604, 757-762. PubMed  Europe PubMed DOI
2020
6. Noguera,M.E., Jakoncic,J. and Ermacora,M.R.
   High-resolution structure of intramolecularly proteolyzed human mucin-1 SEA domain
   Biochim Biophys Acta Proteins Proteom1868, 140361-140361. PubMed  Europe PubMed DOI
2019
7. Bassilana,F., Nash,M. and Ludwig,M.G.
   Adhesion G protein-coupled receptors: opportunities for drug discovery
   Nat Rev Drug Discov18, 869-884. PubMed  Europe PubMed DOI
8. Folts,C.J., Giera,S., Li,T. and Piao,X.
   Adhesion G protein-coupled receptors as drug targets for neurological diseases
   Trends Pharmacol Sci40, 278-293. PubMed  Europe PubMed DOI  S
9. Kashyap,P., Ng,C., Wang,Z., Li,B., Arif Pavel,M., Martin,H. and Yu,Y.
   A PKD1L3 splice variant in taste buds is not cleaved at the G protein-coupled receptor proteolytic site
   Biochem Biophys Res Commun512, 812-818. PubMed  Europe PubMed DOI  M
2018
10. Arakaki,A.K.S., Pan,W.A. and Trejo,J.
    GPCRs in cancer: protease-activated receptors, endocytic adaptors and signaling
    Int J Mol Sci19, PubMed  Europe PubMed DOI
11. Purcell,R.H. and Hall,R.A.
    Adhesion G protein-coupled receptors as drug targets
    Annu Rev Pharmacol Toxicol58, 429-449. PubMed  Europe PubMed DOI
12. Zhang,Q., Zheng,Y.W., Coughlin,S.R. and Shu,X.
    A rapid fluorogenic GPCR-beta-arrestin interaction assay
    Protein Sci27, 874-879. PubMed  Europe PubMed DOI
2017
13. Lin,H.H., Hsiao,C.C., Pabst,C., Hebert,J., Schoneberg,T. and Hamann,J.
    Adhesion GPCRs in regulating immune responses and inflammation
    Adv Immunol136, 163-201. PubMed  Europe PubMed DOI
14. Salzman,G.S., Zhang,S., Gupta,A., Koide,A., Koide,S. and Arac,D.
    Stachel-independent modulation of GPR56/ADGRG1 signaling by synthetic ligands directed to its extracellular region
    Proc Natl Acad Sci U S A114, 10095-10100. PubMed  Europe PubMed DOI
2016
15. Arac,D., Strater,N. and Seiradake,E.
    Understanding the structural basis of adhesion GPCR functions
    Handb Exp Pharmacol234, 67-82. PubMed  Europe PubMed DOI
16. de Graaf,C., Nijmeijer,S., Wolf,S. and Ernst,O.P.
    7TM Domain structure of adhesion GPCRs
    Handb Exp Pharmacol234, 43-66. PubMed  Europe PubMed DOI  S
17. Hamann,J. and Petrenko,A.G.
    Introduction: history of the adhesion GPCR field
    Handb Exp Pharmacol234, 1-11. PubMed  Europe PubMed DOI  S
18. Kishore,A. and Hall,R.A.
    Versatile signaling activity of adhesion GPCRs
    Handb Exp Pharmacol234, 127-146. PubMed  Europe PubMed DOI
19. Krishnan,A., Nijmeijer,S., de Graaf,C. and Schioth,H.B.
    Classification, nomenclature, and structural aspects of adhesion GPCRs
    Handb Exp Pharmacol234, 15-41. PubMed  Europe PubMed DOI
20. Nieberler,M., Kittel,R.J., Petrenko,A.G., Lin,H.H. and Langenhan,T.
    Control of adhesion GPCR function through proteolytic processing
    Handb Exp Pharmacol234, 83-109. PubMed  Europe PubMed DOI
21. Trudel,M., Yao,Q. and Qian,F.
    The role of G-protein-coupled receptor proteolysis site cleavage of polycystin-1 in renal physiology and polycystic kidney disease
    Cells5, PubMed  Europe PubMed DOI
2015
22. Schoneberg,T., Liebscher,I., Luo,R., Monk,K.R. and Piao,X.
    Tethered agonists: a new mechanism underlying adhesion G protein-coupled receptor activation
    J Recept Signal Transduct Res35, 220-223. PubMed  Europe PubMed DOI
2014
23. Liao,Y., Pei,J., Cheng,H. and Grishin,N.V.
    An ancient autoproteolytic domain found in GAIN, ZU5 and nucleoporin98
    J Mol Biol426, 3935-3945. PubMed  Europe PubMed DOI
24. Liebscher,I., Ackley,B., Arac,D., Ariestanti,D.M., Aust,G., Bae,B.I., Bista,B.R., Bridges,J.P., Duman,J.G., Engel,F.B., Giera,S., Goffinet,A.M., Hall,R.A., Hamann,J., Hartmann,N., Lin,H.H., Liu,M., Luo,R., Mogha,A., Monk,K.R., Peeters,M.C., Promel,S., Ressl,S., Schioth,H.B., Sigoillot,S.M., Song,H., Talbot,W.S., Tall,G.G., White,J.P., Wolfrum,U., Xu,L. and Piao,X.
    New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors
    Ann N Y Acad Sci1333, 43-64. PubMed  Europe PubMed DOI
2013
25. Langenhan,T., Aust,G. and Hamann,J.
    Sticky signaling - adhesion class g protein-coupled receptors take the stage
    Sci Signal6, re3-re3. PubMed  Europe PubMed DOI
2012
26. Arac,D., Boucard,A.A., Bolliger,M.F., Nguyen,J., Soltis,S.M., Sudhof,T.C. and Brunger,A.T.
    A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis
    EMBO J31, 1364-1378. PubMed  Europe PubMed DOI  S
27. Arac,D., Aust,G., Calebiro,D., Engel,F.B., Formstone,C., Goffinet,A., Hamann,J., Kittel,R.J., Liebscher,I., Lin,H.H., Monk,K.R., Petrenko,A., Piao,X., Promel,S., Schioth,H.B., Schwartz,T.W., Stacey,M., Ushkaryov,Y.A., Wobus,M., Wolfrum,U., Xu,L. and Langenhan,T.
    Dissecting signaling and functions of adhesion G protein-coupled receptors
    Ann N Y Acad Sci1276, 1-25. PubMed  Europe PubMed DOI
28. Tesmer,J.J.
    A GAIN in understanding autoproteolytic G protein-coupled receptors and polycystic kidney disease proteins
    EMBO J31, 1334-1335. PubMed  Europe PubMed DOI  V
2011
29. Lin,H.H., Stacey,M., Yona,S. and Chang,G.W.
    GPS proteolytic cleavage of adhesion-GPCRs
    Adv Exp Med Biol706, 49-58. DOI  V
2010
30. Deyev,I.E. and Petrenko,A.G.
    Regulation of CIRL-1 proteolysis and trafficking
    Biochimie92, 418-422. PubMed  Europe PubMed DOI
2007
31. Bjarnadottir,T.K., Fredriksson,R. and Schioth,H.B.
    The adhesion GPCRs: a unique family of G protein-coupled receptors with important roles in both central and peripheral tissues
    Cell Mol Life Sci64, 2104-2119. PubMed  Europe PubMed DOI
32. Bjarnadottir,T.K., Geirardsdottir,K., Ingemansson,M., Mirza,M.A., Fredriksson,R. and Schioth,H.B.
    Identification of novel splice variants of Adhesion G protein-coupled receptors
    Gene387, 38-48. PubMed  Europe PubMed DOI
2002
33. [YEAR:29-11-2002]Krasnoperov,V., Lu,Y., Buryanovsky,L., Neubert,T.A., Ichtchenko,K. and Petrenko,A.G.
    Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site (GPS) motif
    J Biol Chem277, 46518-46526. PubMed  Europe PubMed DOI
2000
34. Stacey,M., Lin,H.H., Gordon,S. and McKnight,A.J.
    LNB-TM7, a group of seven-transmembrane proteins related to family-B G-protein-coupled receptors
    Trends Biochem Sci25, 284-289. PubMed  Europe PubMed DOI