Literature for peptidase P02.011: latrophilin 3

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Perry-Hauser,N.A., Du Rand,J.R., Lee,K.H., Shi,L. and Javitch,J.A.
    N-terminal fragment shedding contributes to signaling of the full-length adhesion receptor ADGRL3
    J Biol Chem (2025) , 108174-108174. PubMed  Europe PubMed DOI
  2. 2024
  3. Goto,T., Teramoto,Y., Nagata,Y. and Miyamoto,H.
    Latrophilin-3 as a downstream effector of the androgen receptor induces bladder cancer progression
    Discov Oncol (2024) 15, 440-440. PubMed  Europe PubMed DOI  PMC  EPMC  K
  4. Goto,T., Yasui,M., Teramoto,Y., Nagata,Y., Mizushima,T. and Miyamoto,H.
    Latrophilin-3 as a downstream effector of the androgen receptor induces urothelial tumorigenesis
    Mol Carcinog (2024) PubMed  Europe PubMed DOI  K
  5. Wang,S., DeLeon,C., Sun,W., Quake,S.R., Roth,B.L. and Sudhof,T.C.
    Alternative splicing of latrophilin-3 controls synapse formation
    Nature (2024) 626, 128-135. PubMed  Europe PubMed DOI  PMC  EPMC
  6. 2023
  7. Bui,D.L.H., Roach,A., Li,J., Bandekar,S.J., Orput,E., Raghavan,R., Arac,D. and Sando,R.C.
    The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms
    Cell Rep (2023) 42, 112552-112552. PubMed  Europe PubMed DOI
  8. Ojeda-Muniz,E.Y., Rodriguez-Hernandez,B., Correoso-Brana,K.G., Segura-Landa,P.L. and Boucard,A.A.
    Biased signalling is structurally encoded as an autoproteolysis event in adhesion G protein-coupled receptor Latrophilin-3/ADGRL3
    Basic Clin Pharmacol Toxicol (2023) 133, 342-352. PubMed  Europe PubMed DOI
  9. Zhong,B.L., Lee,C.E., Vachharajani,V.T., Bauer,M.S., Sudhof,T.C. and Dunn,A.R.
    Piconewton Forces Mediate GAIN Domain Dissociation of the Latrophilin-3 Adhesion GPCR
    Nano Lett (2023) 23, 9187-9194. PubMed  Europe PubMed DOI
  10. 2022
  11. Barros-Alvarez,X., Nwokonko,R.M., Vizurraga,A., Matzov,D., He,F., Papasergi-Scott,M.M., Robertson,M.J., Panova,O., Yardeni,E.H., Seven,A.B., Kwarcinski,F.E., Su,H., Peroto,M.C., Meyerowitz,J.G., Shalev-Benami,M., Tall,G.G. and Skiniotis,G.
    The tethered peptide activation mechanism of adhesion GPCRs
    Nature (2022) 604, 757-762. PubMed  Europe PubMed DOI
  12. Perry-Hauser,N.A., VanDyck,M.W., Lee,K.H., Shi,L. and Javitch,J.A.
    Disentangling autoproteolytic cleavage from tethered agonist-dependent activation of the adhesion receptor ADGRL3
    J Biol Chem (2022) 298, 102594-102594. PubMed  Europe PubMed DOI  PMC  EPMC
  13. 2021
  14. Regan,S.L., Williams,M.T. and Vorhees,C.V.
    Latrophilin-3 disruption: Effects on brain and behavior
    Neurosci Biobehav Rev (2021) 127, 619-629. PubMed  Europe PubMed DOI  V
  15. Sando,R. and Sudhof,T.C.
    Latrophilin GPCR signaling mediates synapse formation
    elife (2021) 10 PubMed  Europe PubMed DOI  PMC  EPMC
  16. 2015
  17. Jackson,V.A., del Toro,D., Carrasquero,M., Roversi,P., Harlos,K., Klein,R. and Seiradake,E.
    Structural basis of latrophilin-FLRT interaction
    Structure (2015) 23, 774-781. PubMed  Europe PubMed DOI  PMC  EPMC  S
  18. Lu,Y.C., Nazarko,O.V., Sando R 3rd, Salzman,G.S., Sudhof,T.C. and Arac,D.
    Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion
    Structure (2015) 23, 1678-1691. PubMed  Europe PubMed DOI  S
  19. Ranaivoson,F.M., Liu,Q., Martini,F., Bergami,F., von Daake,S., Li,S., Lee,D., Demeler,B., Hendrickson,W.A. and Comoletti,D.
    Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development
    Structure (2015) 23, 1665-1677. PubMed  Europe PubMed DOI  S
  20. 1999
  21. Ichtchenko,K., Bittner,M.A., Krasnoperov,V., Little,A.R., Chepurny,O., Holz,R.W. and Petrenko,A.G.
    A novel ubiquitously expressed alpha-latrotoxin receptor is a member of the CIRL family of G-protein-coupled receptors
    J Biol Chem (1999) 274, 5491-5498. PubMed  Europe PubMed DOI