Literature for peptidase M85.001: NleC peptidase (Escherichia coli)

(Topics flags: S Structure, P Specificity. To select only the references relevant to a single topic, click the link above. See explanation.)

2024
1. Freitas,I.L., Macedo,M.F., Oliveira,L., Oliveira,P., do Vale,A. and dos Santos,N.M.S.
   AIP56, an AB toxin secreted by Photobacterium damselae subsp. piscicida, has tropism for myeloid cells
   Front Immunol15, 1527088-1527088. PubMed  Europe PubMed DOI
2023
2. Lisboa,J., Pereira,C., Pinto,R.D., Rodrigues,I.S., Pereira,L.M.G., Pinheiro,B., Oliveira,P., Pereira,P.J.B., Azevedo,J.E., Durand,D., Benz,R., do Vale,A. and dos Santos,N.M.S.
   Unconventional structure and mechanisms for membrane interaction and translocation of the NF-kappaB-targeting toxin AIP56
   Nat Commun14, 7431-7431. PubMed  Europe PubMed DOI
3. Rudenko,O., Baseggio,L., McGuigan,F. and Barnes,A.C.
   Transforming the untransformable with knockout minicircles: High-efficiency transformation and vector-free allelic exchange knockout in the fish pathogen Photobacterium damselae
   Microbiologyopen12, e1374-e1374. PubMed  Europe PubMed DOI
4. Verster,K.I., Cinege,G., Lipinszki,Z., Magyar,L.B., Kurucz,E., Tarnopol,R.L., Abraham,E., Darula,Z., Karageorgi,M., Tamsil,J.A., Akalu,S.M., Ando,I. and Whiteman,N.K.
   Evolution of insect innate immunity through domestication of bacterial toxins
   Proc Natl Acad Sci U S A120, e2218334120-e2218334120. PubMed  Europe PubMed DOI
2019
5. Pereira,C., Rodrigues,I.S., Pereira,L.M.G., Lisboa,J., Pinto,R., Araujo,L., Oliveira,P., Benz,R., M S Dos Santos,N. and do Vale,A.
   Role of AIP56 disulphide bond and its reduction by cytosolic redox systems for efficient intoxication
   Cell Microbiole13109-e13109. PubMed  Europe PubMed DOI
6. Rodrigues,I.S., Pereira,L.M.G., Lisboa,J., Pereira,C., Oliveira,P., dos Santos,N.M.S. and do Vale,A.
   Involvement of Hsp90 and cyclophilins in intoxication by AIP56, a metalloprotease toxin from Photobacterium damselae subsp. piscicida
   Sci Rep9, 9019-9019. PubMed  Europe PubMed DOI
2017
7. do Vale,A., Pereira,C., Osorio,C.R. and dos Santos,N.M.S.
   The apoptogenic toxin AIP56 is secreted by the Type II secretion system of Photobacterium damselae subsp. piscicida
   Toxins (Basel)9, PubMed  Europe PubMed DOI
8. Stolle,A.S., Norkowski,S., Korner,B., Schmitz,J., Luken,L., Frankenberg,M., Ruter,C. and Schmidt,M.A.
   T3SS-Independent uptake of the short-trip toxin-related recombinant NleC effector of enteropathogenic Escherichia coli leads to NF-kappaB p65 cleavage
   Front Cell Infect Microbiol7, 119-119. PubMed  Europe PubMed DOI
2015
9. Giogha,C., Wong Fok Lung,T., Muhlen,S., Pearson,J.S. and Hartland,E.L.
   Substrate recognition by the zinc metalloprotease effector NleC from enteropathogenic Escherichia coli
   Cell Microbiol17, 1766-1778. PubMed  Europe PubMed DOI
10. Hodgson,A., Wier,E.M., Fu,K., Sun,X., Yu,H., Zheng,W., Sham,H.P., Johnson,K., Bailey,S., Vallance,B.A. and Wan,F.
    Metalloprotease NleC suppresses host NF-kappaB/inflammatory responses by cleaving p65 and interfering with the p65/RPS3 interaction
    PLoS Pathog11, e1004705-e1004705. PubMed  Europe PubMed DOI
2014
11. Li,W., Liu,Y., Sheng,X., Yin,P., Hu,F., Liu,Y., Chen,C., Li,Q., Yan,C. and Wang,J.
    Structure and mechanism of a type III secretion protease, NleC
    Acta Crystallogr D Biol Crystallogr70, 40-47. PubMed  Europe PubMed DOI  S
12. Pereira,L.M., Pinto,R.D., Silva,D.S., Moreira,A.R., Beitzinger,C., Oliveira,P., Sampaio,P., Benz,R., Azevedo,J.E., Dos Santos,N.M. and do Vale,A.
    Intracellular trafficking of AIP56, an NF-kappaB-cleaving toxin from Photobacterium damselae subsp. piscicida
    Infect Immun82, 5270-5285. PubMed  Europe PubMed DOI
13. Turco,M.M. and Sousa,M.C.
    The structure and specificity of the type III secretion system effector NleC suggest a DNA mimicry mechanism of substrate recognition
    Biochemistry53, 5131-5139. PubMed  Europe PubMed DOI  P  S
2013
14. Silva,D.S., Pereira,L.M., Moreira,A.R., Ferreira-da-Silva,F., Brito,R.M., Faria,T.Q., Zornetta,I., Montecucco,C., Oliveira,P., Azevedo,J.E., Pereira,P.J., Macedo-Ribeiro,S., do Vale,A. and Dos Santos,N.M.
    The apoptogenic toxin AIP56 is a metalloprotease A-B toxin that cleaves NF-kappab P65
    PLoS Pathog9, e1003128-e1003128. PubMed  Europe PubMed DOI
2011
15. Baruch,K., Gur-Arie,L., Nadler,C., Koby,S., Yerushalmi,G., Ben-Neriah,Y., Yogev,O., Shaulian,E., Guttman,C., Zarivach,R. and Rosenshine,I.
    Metalloprotease type III effectors that specifically cleave JNK and NF-kappaB
    EMBO J30, 221-231. PubMed  Europe PubMed DOI
16. Costa-Ramos,C., Vale,A., Ludovico,P., Dos Santos,N.M. and Silva,M.T.
    The bacterial exotoxin AIP56 induces fish macrophage and neutrophil apoptosis using mechanisms of the extrinsic and intrinsic pathways
    Fish Shellfish Immunol30, 173-181. PubMed  Europe PubMed DOI
17. Muhlen,S., Ruchaud-Sparagano,M.H. and Kenny,B.
    Proteasome-independent degradation of canonical NFkappaB complex components by the NleC protein of pathogenic Escherichia coli
    J Biol Chem286, 5100-5107. PubMed  Europe PubMed DOI
18. Pearson,J.S., Riedmaier,P., Marches,O., Frankel,G. and Hartland,E.L.
    A type III effector protease NleC from enteropathogenic Escherichia coli targets NF-kappaB for degradation
    Mol Microbiol80, 219-230. PubMed  Europe PubMed DOI
19. Sham,H.P., Shames,S.R., Croxen,M.A., Ma,C., Chan,J.M., Khan,M.A., Wickham,M.E., Deng,W., Finlay,B.B. and Vallance,B.A.
    Attaching and effacing bacterial effector NleC suppresses epithelial inflammatory responses by inhibiting NF-kappaB and p38 mitogen-activated protein kinase activation
    Infect Immun79, 3552-3562. PubMed  Europe PubMed DOI
20. Shames,S.R., Bhavsar,A.P., Croxen,M.A., Law,R.J., Mak,S.H., Deng,W., Li,Y., Bidshari,R., de Hoog,C.L., Foster,L.J. and Finlay,B.B.
    The pathogenic Escherichia coli type III secreted protease NleC degrades the host acetyltransferase p300
    Cell Microbiol13, 1542-1557. PubMed  Europe PubMed DOI
2010
21. Silva,M.T., Dos Santos,N.M. and do Vale,A.
    AIP56: a novel bacterial apoptogenic toxin
    Toxins (Basel)2, 905-918. PubMed  Europe PubMed DOI
22. Yen,H., Ooka,T., Iguchi,A., Hayashi,T., Sugimoto,N. and Tobe,T.
    NleC, a type III secretion protease, compromises NF-kappaB activation by targeting p65/RelA
    PLoS Pathog6, e1001231-e1001231. PubMed  Europe PubMed DOI
2005
23. do Vale,A., Silva,M.T., Dos Santos,N.M., Nascimento,D.S., Reis-Rodrigues,P., Costa-Ramos,C., Ellis,A.E. and Azevedo,J.E.
    AIP56, a novel plasmid-encoded virulence factor of Photobacterium damselae subsp. piscicida with apoptogenic activity against sea bass macrophages and neutrophils
    Mol Microbiol58, 1025-1038. PubMed  Europe PubMed DOI
24. Marches,O., Wiles,S., Dziva,F., La Ragione,R.M., Schuller,S., Best,A., Phillips,A.D., Hartland,E.L., Woodward,M.J., Stevens,M.P. and Frankel,G.
    Characterization of two non-locus of enterocyte effacement-encoded type III-translocated effectors, NleC and NleD, in attaching and effacing pathogens
    Infect Immun73, 8411-8417. PubMed  Europe PubMed DOI