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Literature for peptidase M67.004: Brcc36 isopeptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature

(Topics flags: S Structure, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Chandler,F., Reddy,P.A.N., Bhutda,S., Ross,R.L., Datta,A., Walden,M., Walker,K., Di Donato,S., Cassel,J.A., Prakesch,M.A., Aman,A., Datti,A., Campbell,L.J., Foglizzo,M., Bell,L., Stein,D.N., Ault,J.R., Al-Awar,R.S., Calabrese,A.N., Sicheri,F., Del Galdo,F., Salvino,J.M., Greenberg,R.A. and Zeqiraj,E.
    Molecular glues that inhibit deubiquitylase activity and inflammatory signaling
    Nat Struct Mol Biol PubMed  Europe PubMed DOI
    2. 2024
  2. Feng,X., He,S., Chen,Y. and Zhang,L.
    Deubiquitinase BRCC3 promotes the migration, invasion and EMT progression of colon adenocarcinoma by stabilizing MET expression
    Genes Genomics46, 637-646. PubMed  Europe PubMed DOI  K
  3. Huang,Q., Zheng,S., Gu,H., Yang,Z., Lu,Y., Yu,X. and Guo,G.
    The deubiquitinase BRCC3 increases the stability of ZEB1 and promotes the proliferation and metastasis of triple-negative breast cancer cells
    Acta Biochim Biophys Sin (Shanghai)56, 564-575. PubMed  Europe PubMed DOI
  4. Huang,X., Tan,J., Ji,Y., Luo,J., Zhao,Y. and Zhao,J.
    BRCC3 mediates inflammation and pyroptosis in cerebral ischemia/reperfusion injury by activating the NLRP6 inflammasome
    CNS Neurosci Ther30, e14697-e14697. PubMed  Europe PubMed DOI  K
  5. Li,Y., Jiang,C., Liu,Q., Zhou,P., Tian,D., Zeng,Y. and Xiang,M.
    USP15 facilitates the progression of bladder cancer by amplifying the activation of the NF-kappaB signaling pathway
    Aging (Albany NY)16, 6757-6772. PubMed  Europe PubMed DOI
  6. Liu,J., Isaji,T., Komatsu,S., Sun,Y., Xu,X., Fukuda,T., Fujimura,T., Takahashi,S. and Gu,J.
    BRCC36 associates with FLT3-ITD to regulate its protein stability and intracellular signaling in acute myeloid leukemia
    Cancer Sci115, 1196-1208. PubMed  Europe PubMed DOI
  7. Wang,B., Li,M., Cao,D., Sun,Q., Yu,W., Ma,J., Ren,H., Xu,G. and Zhou,L.
    Lys-63-specific deubiquitinase BRCC36 enhances the sensitivity of multiple myeloma cells to lenalidomide by inhibiting lysosomal degradation of cereblon
    Cell Mol Life Sci81, 349-349. PubMed  Europe PubMed DOI
  8. Wang,H., Shu,L., Lv,C., Liu,N., Long,Y., Peng,X., Ling,H., Tao,T., Tang,J., Cheng,Y., Liu,S., Xiao,D. and Tao,Y.
    BRCC36 Deubiquitinates HMGCR to Regulate the Interplay Between Ferroptosis and Pyroptosis
    Adv Sci (Weinh)11, e2304263-e2304263. PubMed  Europe PubMed DOI
    9. 2023
  9. Yalcinkaya,M., Liu,W., Thomas,L.A., Olszewska,M., Xiao,T., Abramowicz,S., Papapetrou,E.P., Westerterp,M., Wang,N., Tabas,I. and Tall,A.R.
    BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Tet2 Clonal Hematopoiesis
    Circulation148, 1764-1777. PubMed  Europe PubMed DOI  I
  10. Zhang,W., Liu,K., Ren,G.M., Wang,Y., Wang,T., Liu,X., Li,D.X., Xiao,Y., Chen,X., Li,Y.T., Zhan,Y.Q., Xiang,S.S., Chen,H., Gao,H.Y., Zhao,K., Yu,M., Ge,C.H., Li,C.Y., Ge,Z.Q., Yang,X.M. and Yin,R.H.
    BRISC is required for optimal activation of NF-kappaB in Kupffer cells induced by LPS and contributes to acute liver injury
    Cell Death Dis14, 743-743. PubMed  Europe PubMed DOI
    11. 2022
  11. Jiang,Q., Foglizzo,M., Morozov,Y.I., Yang,X., Datta,A., Tian,L., Thada,V., Li,W., Zeqiraj,E. and Greenberg,R.A.
    Autologous K63 deubiquitylation within the BRCA1-A complex licenses DNA damage recognition
    J Cell Biol221, PubMed  Europe PubMed DOI
  12. Li,Q., Ma,Y., Chang,F., Xu,Y., Deng,J., Duan,J., Jiang,W., He,Q., Xu,L., Zhong,L., Shao,G. and Li,L.
    The deubiquitinating enzyme complex BRISC regulates Aurora B activation via lysine-63-linked ubiquitination in mitosis
    Commun Biol5, 1335-1335. PubMed  Europe PubMed DOI
  13. Liu,D., Zhao,Z., She,Y., Zhang,L., Chen,X., Ma,L. and Cui,J.
    TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation
    Proc Natl Acad Sci U S A119, PubMed  Europe PubMed DOI
  14. Liu,D., Jin,S. and Cui,J.
    The TRIM14-USP14-BRCC3 complex epigenetically regulates inflammation through inhibiting OPTN-mediated autophagic degradation of KDM4D
    Autophagy18, 2001-2002. PubMed  Europe PubMed DOI
  15. Liu,D., Zhao,Z., She,Y., Zhang,L., Chen,X., Ma,L. and Cui,J.
    TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation
    Proc Natl Acad Sci U S A119, e2113454119-e2113454119. PubMed  Europe PubMed DOI
  16. Pan,X., Wu,S., Wei,W., Chen,Z., Wu,Y. and Gong,K.
    Structural and Functional Basis of JAMM Deubiquitinating Enzymes in Disease
    Biomolecules12, PubMed  Europe PubMed DOI  V
  17. Zhang,C.H., Qin,K., Tian,S.L., Han,Y., Xu,S.Y. and Shao,X.Y.
    Identification and Verification of the Ability of Cdk5 to Phosphorylate Deubiquitinating Enzyme BRCC3 In Vitro
    Bull Exp Biol Med172, 701-708. PubMed  Europe PubMed DOI
    18. 2021
  18. Huang,X., Gan,H., Tan,J., Wang,T., Zhao,J. and Zhao,Y.
    BRCC3 promotes activation of the NLRP6 inflammasome following cerebral ischemia/reperfusion (I/R) injury in rats
    Neurosci Lett756, 135954-135954. PubMed  Europe PubMed DOI  K
  19. Ren,G.M., Li,J., Zhang,X.C., Wang,Y., Xiao,Y., Zhang,X.Y., Liu,X., Zhang,W., Ma,W.B., Zhang,J., Li,Y.T., Tao,S.S., Wang,T., Liu,K., Chen,H., Zhan,Y.Q., Yu,M., Li,C.Y., Ge,C.H., Tian,B.X., Dou,G.F., Yang,X.M. and Yin,R.H.
    Pharmacological targeting of NLRP3 deubiquitination for treatment of NLRP3-associated inflammatory diseases
    Sci Immunol6, PubMed  Europe PubMed DOI  I
  20. Zhang,L., Huang,F., Liu,J., Xu,Y., Miao,Y., Yuan,Y., Chen,X., Zhang,H.G., Wang,J., Zheng,H. and Zuo,Y.
    HSV-1-encoded ICP0 degrades the host deubiquitinase BRCC36 to antagonize interferon antiviral response
    Mol Immunol135, 28-35. PubMed  Europe PubMed DOI
  21. Zhang,W., Tao,S.S., Wang,T., Zhang,J., Liu,X., Li,Y.T., Chen,H., Zhan,Y.Q., Yu,M., Ge,C.H., Li,C.Y., Ren,G.M., Yang,X.M. and Yin,R.H.
    ABRO1 stabilizes the deubiquitinase BRCC3 through inhibiting its degradation mediated by the E3 ubiquitin ligase WWP2
    FEBS Lett595, 169-182. PubMed  Europe PubMed DOI
  22. Zhou,L., Liu,T., Huang,B., Luo,M., Chen,Z., Zhao,Z., Wang,J., Leung,D., Yang,X., Chan,K.W., Liu,Y., Xiong,L., Chen,P., Wang,H., Ye,L., Liang,H., Masters,S.L., Lew,A.M., Gong,S., Bai,F., Yang,J., Pui-Wah,L.e., Yang,W., Zhang,Y., Lau,Y.L., Geng,L., Zhang,Y. and Cui,J.
    Excessive deubiquitination of NLRP3-R779C variant contributes to very-early-onset inflammatory bowel disease development
    J Allergy Clin Immunol147, 267-279. PubMed  Europe PubMed DOI
    23. 2020
  23. Cheng,Q., Feng,Q., Xu,Y., Zuo,Y., Liu,J., Yuan,Y., Miao,Y., Liu,Y., Lei,L., Guo,T., Zhang,L., Wu,D. and Zheng,H.
    BRCC36 functions noncatalytically to promote antiviral response by maintaining STAT1 protein stability
    Eur J Immunol PubMed  Europe PubMed DOI
  24. Cheng,X., Xu,S., Zhang,C., Qin,K., Yan,J. and Shao,X.
    The BRCC3 regulated by Cdk5 promotes the activation of neuronal NLRP3 inflammasome in Parkinson's disease models
    Biochem Biophys Res Commun522, 647-654. PubMed  Europe PubMed DOI
  25. Meyer,T., Jahn,N., Lindner,S., Röhner,L., Dolnik,A., Weber,D., Scheffold,A., Köpff,S., Paschka,P., Gaidzik,V.I., Heckl,D., Wiese,S., Ebert,B.L., Döhner,H., Bullinger,L., Döhner,K. and Krönke,J.
    Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1)
    Leukemia34, 404-415. PubMed  Europe PubMed DOI
  26. Rabl,J.
    BRCA1-A and BRISC: Multifunctional Molecular Machines for Ubiquitin Signaling
    Biomolecules10, 1503-1503. PubMed  Europe PubMed DOI
  27. Rasaei,R., Sarodaya,N., Kim,K.S., Ramakrishna,S. and Hong,S.H.
    Importance of Deubiquitination in Macrophage-Mediated Viral Response and Inflammation
    Int J Mol Sci21, PubMed  Europe PubMed DOI  V
    28. 2019
  28. Cai,L., Huo,Z., Yang,H., He,F., Cao,Z., Wu,F., Liu,L. and Sun,B.
    Gene co-expression network analysis identifies BRCC3 as a key regulator in osteogenic differentiation of osteoblasts through a ß-catenin signaling dependent pathway
    Iran J Basic Med Sci22, 173-178. PubMed  Europe PubMed DOI
  29. Donaghy,R., Han,X., Rozenova,K., Lv,K., Jiang,Q., Doepner,M., Greenberg,R.A. and Tong,W.
    The BRISC deubiquitinating enzyme complex limits hematopoietic stem cell expansion by regulating JAK2 K63-ubiquitination
    Blood133, 1560-1571. PubMed  Europe PubMed DOI
  30. Rabl,J., Bunker,R.D., Schenk,A.D., Cavadini,S., Gill,M.E., Abdulrahman,W., Andrés-Pons,A., Luijsterburg,M.S., Ibrahim,A.F., Branigan,E., Aguirre,J.D., Marceau,A.H., Guérillon,C., Bouwmeester,T., Hassiepen,U., Peters,A.H., Renatus,M., Gelman,L., Rubin,S.M., Mailand,N., van,A.t., Hay,R.T. and Thomä,N.H.
    Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation
    Mol Cell75, 483-497. PubMed  Europe PubMed DOI
  31. Rao,Z., Chen,X., Wu,J., Xiao,M., Zhang,J., Wang,B., Fang,L., Zhang,H., Wang,X., Yang,S. and Chen,Y.
    Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination
    Front Immunol10, 2783-2783. PubMed  Europe PubMed DOI
  32. Ren,G., Zhang,X., Xiao,Y., Zhang,W., Wang,Y., Ma,W., Wang,X., Song,P., Lai,L., Chen,H., Zhan,Y., Zhang,J., Yu,M., Ge,C., Li,C., Yin,R. and Yang,X.
    ABRO1 promotes NLRP3 inflammasome activation through regulation of NLRP3 deubiquitination
    EMBO J38, e100376-e100376. PubMed  Europe PubMed DOI
  33. Singh,M., Kumari,B. and Yadav,U.C.S.
    Regulation of oxidized LDL-induced inflammatory process through NLRP3 inflammasome activation by the deubiquitinating enzyme BRCC36
    Inflamm Res68, 999-1010. PubMed  Europe PubMed DOI
  34. Walden,M., Tian,L., Ross,R.L., Sykora,U.M., Byrne,D.P., Hesketh,E.L., Masandi,S.K., Cassel,J., George,R., Ault,J.R., El,O.u., Pawlowski,K., Salvino,J.M., Eyers,P.A., Ranson,N.A., Del,G.a., Greenberg,R.A. and Zeqiraj,E.
    Metabolic control of BRISC-SHMT2 assembly regulates immune signalling
    Nature570, 194-199. PubMed  Europe PubMed DOI
  35. Wang,C.Y., Deneen,B. and Tzeng,S.F.
    BRCA1/BRCA2-containing complex subunit 3 controls oligodendrocyte differentiation by dynamically regulating lysine 63-linked ubiquitination
    Glia67, 1775-1792. PubMed  Europe PubMed DOI
    36. 2018
  36. Liu,Q., Wu,Y., Qin,Y., Hu,J., Xie,W., Qin,F.X. and Cui,J.
    Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses
    Sci Adv4, eaar2824-eaar2824. PubMed  Europe PubMed DOI
  37. Xu,M., Moresco,J.J., Chang,M., Mukim,A., Smith,D., Diedrich,J.K., Yates JR 3rd and Jones,K.A.
    SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy
    PLoS Pathog14, e1007071-e1007071. PubMed  Europe PubMed DOI
  38. Zhang,F. and Zhou,Q.
    Knockdown of BRCC3 exerts an anti-tumor effect on cervical cancer in vitro
    Mol Med Rep18, 4886-4894. PubMed  Europe PubMed DOI
    39. 2017
  39. Chi,W., Hua,X., Chen,X., Bian,F., Yuan,X., Zhang,L., Wang,X., Chen,D., Deng,R., Li,Z., Liu,Y., De Paiva,C.S., Pflugfelder,S.C. and Li,D.Q.
    Mitochondrial DNA oxidation induces imbalanced activity of NLRP3/NLRP6 inflammasomes by activation of caspase-8 and BRCC36 in dry eye
    J Autoimmun80, 65-76. PubMed  Europe PubMed DOI
  40. Lauinger,L., Li,J., Shostak,A., Cemel,I.A., Ha,N., Zhang,Y., Merkl,P.E., Obermeyer,S., Stankovic-Valentin,N., Schafmeier,T., Wever,W.J., Bowers,A.A., Carter,K.P., Palmer,A.E., Tschochner,H., Melchior,F., Deshaies,R.J., Brunner,M. and Diernfellner,A.
    Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases
    Nat Chem Biol13, 709-714. PubMed  Europe PubMed DOI  I
  41. Tripathi,E. and Smith,S.
    Cell cycle-regulated ubiquitination of tankyrase 1 by RNF8 and ABRO1/BRCC36 controls the timing of sister telomere resolution
    EMBO J36, 503-519. PubMed  Europe PubMed DOI
    42. 2016
  42. Ng,H.M., Wei,L., Lan,L. and Huen,M.S.
    The Lys63-deubiquitylating enzyme BRCC36 limits DNA break processing and repair
    J Biol Chem291, 16197-16207. PubMed  Europe PubMed DOI
  43. Sun,Z.Z., Zhang,T., Ning,K., Zhu,R., Liu,F., Tang,S.C., Jiang,B. and Hua,D.
    B7-H3 upregulates BRCC3 expression, antagonizing DNA damage caused by 5-Fu
    Oncol Rep36, 231-238. PubMed  Europe PubMed DOI
    44. 2015
  44. Huang,D., Nagata,Y., Grossmann,V., Radivoyevitch,T., Okuno,Y., Nagae,G., Hosono,N., Schnittger,S., Sanada,M., Przychodzen,B., Kon,A., Polprasert,C., Shen,W., Clemente,M.J., Phillips,J.G., Alpermann,T., Yoshida,K., Nadarajah,N., Sekeres,M.A., Oakley,K., Nguyen,N., Shiraishi,Y., Shiozawa,Y., Chiba,K., Tanaka,H., Koeffler,H.P., Klein,H.U., Dugas,M., Aburatani,H., Miyano,S., Haferlach,C., Kern,W., Haferlach,T., Du,Y., Ogawa,S. and Makishima,H.
    BRCC3 mutations in myeloid neoplasms
    Haematologica100, 1051-1057. PubMed  Europe PubMed DOI
  45. Tu,Z., Xu,B., Qu,C., Tao,Y., Chen,C., Hua,W., Feng,G., Chang,H., Liu,Z., Li,G., Jiang,C., Yi,W., Zeng,M. and Xia,Y.
    BRCC3 acts as a prognostic marker in nasopharyngeal carcinoma patients treated with radiotherapy and mediates radiation resistance in vitro
    Radiat Oncol10, 123-123. PubMed  Europe PubMed DOI
  46. Yan,K., Li,L., Wang,X., Hong,R., Zhang,Y., Yang,H., Lin,M., Zhang,S., He,Q., Zheng,D., Tang,J., Yin,Y. and Shao,G.
    The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells
    J Cell Biol210, 209-224. PubMed  Europe PubMed DOI
  47. Zeqiraj,E., Tian,L., Piggott,C.A., Pillon,M.C., Duffy,N.M., Ceccarelli,D.F., Keszei,A.F., Lorenzen,K., Kurinov,I., Orlicky,S., Gish,G.D., Heck,A.J., Guarne,A., Greenberg,R.A. and Sicheri,F.
    Higher-order assembly of BRCC36-KIAA0157 is required for DUB activity and biological function
    Mol Cell59, 970-983. PubMed  Europe PubMed DOI  S
    48. 2014
  48. Chai,K.M., Wang,C.Y., Liaw,H.J., Fang,K.M., Yang,C.S. and Tzeng,S.F.
    Downregulation of BRCA1-BRCA2-containing complex subunit 3 sensitizes glioma cells to temozolomide
    Oncotarget5, 10901-10915. PubMed  Europe PubMed DOI
  49. Janczar,S., Fogtman,A., Koblowska,M., Baranska,D., Pastorczak,A., Wegner,O., Kostrzewska,M., Laguna,P., Borowiec,M. and Mlynarski,W.
    Novel severe hemophilia A and moyamoya (SHAM) syndrome caused by Xq28 deletions encompassing F8 and BRCC3 genes
    Blood123, 4002-4004. PubMed  Europe PubMed DOI
    50. 2013
  50. Okamoto,K., Bartocci,C., Ouzounov,I., Diedrich,J.K., Yates,J.R., III and Denchi,E.L.
    A two-step mechanism for TRF2-mediated chromosome-end protection
    Nature494, 502-505. PubMed  Europe PubMed DOI
  51. [YEAR:24-1-2013]Py,B.F., Kim,M.S., Vakifahmetoglu-Norberg,H. and Yuan,J.
    Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity
    Mol Cell49, 331-338. PubMed  Europe PubMed
  52. Zheng,H., Gupta,V., Patterson-Fortin,J., Bhattacharya,S., Katlinski,K., Wu,J., Varghese,B., Carbone,C.J., Aressy,B., Fuchs,S.Y. and Greenberg,R.A.
    A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses
    Cell Rep5, 180-193. DOI
    53. 2012
  53. [YEAR:19-10-2012]Juliana,C., Fernandes-Alnemri,T., Kang,S., Farias,A., Qin,F. and Alnemri,E.S.
    Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
    J Biol Chem287, 36617-36622. PubMed  Europe PubMed
    54. 2011
  54. Cilenti,L., Balakrishnan,M.P., Wang,X.L., Ambivero,C., Sterlicchi,M., Del Monte,F., Ma,X.L. and Zervos,A.S.
    Regulation of Abro1/KIAA0157 during myocardial infarction and cell death reveals a novel cardioprotective mechanism for Lys63-specific deubiquitination
    J Mol Cell Cardiol50, 652-661. PubMed  Europe PubMed DOI
  55. Coleman,K.A. and Greenberg,R.A.
    The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection
    J Biol Chem286, 13669-13680. PubMed  Europe PubMed DOI
  56. Hu,X., Kim,J.A., Castillo,A., Huang,M., Liu,J. and Wang,B.
    NBA1/MERIT40 and BRE interaction is required for the integrity of two distinct deubiquitinating enzyme BRCC36-containing complexes
    J Biol Chem286, 11734-11745. PubMed  Europe PubMed DOI
  57. Miskinyte,S., Butler,M.G., Hervé,D., Sarret,C., Nicolino,M., Petralia,J.D., Bergametti,F., Arnould,M., Pham,V.N., Gore,A.V., Spengos,K., Gazal,S., Woimant,F., Steinberg,G.K., Weinstein,B.M. and Tournier-Lasserve,E.
    Loss of BRCC3 deubiquitinating enzyme leads to abnormal angiogenesis and is associated with syndromic moyamoya
    Am J Hum Genet88, 718-728. PubMed  Europe PubMed DOI
    58. 2010
  58. Cooper,E.M., Boeke,J.D. and Cohen,R.E.
    Specificity of the BRISC deubiquitinating enzyme is not due to selective binding to Lys63-linked polyubiquitin
    J Biol Chem285, 10344-10352. PubMed  Europe PubMed DOI
  59. [YEAR:1-10-2010]Feng,L., Wang,J. and Chen,J.
    The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments
    J Biol Chem285, 30982-30988. PubMed  Europe PubMed
  60. Patterson-Fortin,J., Shao,G., Bretscher,H., Messick,T.E. and Greenberg,R.A.
    Differential regulation of JAMM domain deubiquitinating enzyme activity within the rap80 complex
    J Biol Chem285, 30971-30981. PubMed  Europe PubMed DOI
    61. 2009
  61. Cooper,E.M., Cutcliffe,C., Kristiansen,T.Z., Pandey,A., Pickart,C.M. and Cohen,R.E.
    K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1
    EMBO J28, 621-631. PubMed  Europe PubMed DOI
  62. Shao,G., Patterson-Fortin,J., Messick,T.E., Feng,D., Shanbhag,N., Wang,Y. and Greenberg,R.A.
    MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks
    Genes Dev23, 740-754. PubMed  Europe PubMed DOI
  63. Shao,G., Lilli,D.R., Patterson-Fortin,J., Coleman,K.A., Morrissey,D.E. and Greenberg,R.A.
    The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks
    Proc Natl Acad Sci U S A106, 3166-3171. PubMed  Europe PubMed DOI
    64. 2007
  64. Boudreau,H.E., Broustas,C.G., Gokhale,P.C., Kumar,D., Mewani,R.R., Rone,J.D., Haddad,B.R. and Kasid,U.
    Expression of BRCC3, a novel cell cycle regulated molecule, is associated with increased phospho-ERK and cell proliferation
    Int J Mol Med19, 29-39. PubMed  Europe PubMed
  65. Wang,B. and Elledge,S.J.
    Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage
    Proc Natl Acad Sci U S A104, 20759-20763. PubMed  Europe PubMed DOI
    66. 2006
  66. Chen,X., Arciero,C.A., Wang,C., Broccoli,D. and Godwin,A.K.
    BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation
    Cancer Res66, 5039-5046. PubMed  Europe PubMed DOI
    67. 2003
  67. Dong,Y., Hakimi,M.A., Chen,X., Kumaraswamy,E., Cooch,N.S., Godwin,A.K. and Shiekhattar,R.
    Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair
    Mol Cell12, 1087-1099. DOI
    68. 1992
  68. Kenwrick,S., Levinson,B., Taylor,S., Shapiro,A. and Gitschier,J.
    Isolation and sequence of two genes associated with a CpG island 5' of the factor VIII gene
    Hum Mol Genet1, 179-186. PubMed  Europe PubMed DOI

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