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Literature for peptidase M67.001: PSMD14 peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, M Mutation, P Specificity, I Inhibitor, K Knockout, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Eibach,Y., Kreher,S., Poetsch,M.S., Kho,A.L., Gaertner,U., Clemen,C.S., Schroder,R., Guo,K., Milting,H., Meder,B., Potente,M., Richter,M., Schneider,A., Meiners,S., Gaute,M. and Braun,T.
    The deubiquitinase USP5 prevents accumulation of protein aggregates in cardiomyocytes
    Sci Adv11, eado3852-eado3852. PubMed  Europe PubMed DOI
  2. Lu,J., Wu,H., Zhan,P., Lu,Y., Fang,Q., Luo,C., Wang,F., Wen,J., Xie,C. and Yin,Z.
    PSMD14-mediated deubiquitination of CARM1 facilitates the proliferation and metastasis of hepatocellular carcinoma by inducing the transcriptional activation of FERMT1
    Cell Death Dis16, 141-141. PubMed  Europe PubMed DOI
    3. 2024
  3. Arkinson,C., Gee,C.L., Zhang,Z., Dong,K.C. and Martin,A.
    Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1
    bioRxiv PubMed  Europe PubMed DOI
  4. Guo,X., Mutch,M., Torres,A.Y., Nano,M., Rauth,N., Harwood,J., McDonald,D., Chen,Z., Montell,C., Dai,W. and Montell,D.J.
    The Zn(2+) transporter ZIP7 enhances endoplasmic-reticulum-associated protein degradation and prevents neurodegeneration in Drosophila
    Dev Cell59, 1655-1667. PubMed  Europe PubMed DOI
  5. Htet,Z.M., Dong,K.C. and Martin,A.
    The deubiquitinase Rpn11 functions as an allosteric ubiquitin sensor to promote substrate engagement by the 26S proteasome
    bioRxiv PubMed  Europe PubMed DOI
  6. Lai,J., Kong,W., Fu,Q., Jiang,Z., Sun,B., Ye,X., Kong,J., Wei,S. and Jiang,L.
    PSMD14 is a novel prognostic marker and therapeutic target in osteosarcoma
    Diagn Pathol19, 79-79. PubMed  Europe PubMed DOI  K
  7. Yang,P., Yang,X., Wang,D., Yang,H., Li,Z., Zhang,C., Zhang,S., Zhu,J., Li,X., Su,P. and Zhuang,T.
    PSMD14 stabilizes estrogen signaling and facilitates breast cancer progression via deubiquitinating ERalpha
    Oncogene43, 248-264. PubMed  Europe PubMed DOI  K
  8. Yuan,Y., Li,Y., Wu,X., Bo,J., Zhang,L., Zhang,J., Hu,Y., Chen,Y., Zeng,Y., Wei,X. and Zhang,H.
    POH1 induces Smad3 deubiquitination and promotes lung cancer metastasis
    Cancer Lett582, 216526-216526. PubMed  Europe PubMed DOI
  9. Zhou,B., Luo,Y., Bi,H., Zhang,N., Ma,M., Dong,Z., Ji,N., Zhang,S., Wang,X., Liu,Y., Guo,X., Wei,W., Xie,C., Wu,L., Wan,X., Zheng,M.H., Zhao,B., Li,Y., Hu,C. and Lu,Y.
    Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
    Cell Metab36, 2228-2244. PubMed  Europe PubMed DOI
    10. 2023
  10. Bustamante,H.A., Albornoz,N., Morselli,E., Soza,A. and Burgos,P.V.
    Novel insights into the non-canonical roles of PSMD14/POH1/Rpn11 in proteostasis and in the modulation of cancer progression
    Cell Signal101, 110490-110490. PubMed  Europe PubMed DOI
  11. Guo,X., Mutch,M., Torres,A.Y., Nano,M., McDonald,D., Chen,Z., Montell,C., Dai,W. and Montell,D.J.
    Rescue of proteotoxic stress and neurodegeneration by the Zn (2+) transporter ZIP7
    bioRxiv PubMed  Europe PubMed DOI
  12. Jing,T., Xu,X., Wu,C., Wei,D., Yuan,L., Huang,Y., Liu,Y. and Wang,B.
    POH1 facilitates pancreatic carcinogenesis through MYC-driven acinar-to-ductal metaplasia and is a potential therapeutic target
    Cancer Lett577, 216444-216444. PubMed  Europe PubMed DOI
  13. Liu,Z., Wang,X., Li,C. and Zhao,R.
    The function and mechanism of PSMD14 in promoting progression and resistance to anlotinib in osteosarcoma
    Cancer Cell Int23, 309-309. PubMed  Europe PubMed DOI  K
  14. Xie,G., Dong,K.C., Worden,E.J. and Martin,A.
    High-Throughput Assay for Characterizing Rpn11 Deubiquitinase Activity
    Methods Mol Biol2591, 79-100. PubMed  Europe PubMed DOI
  15. Xiong,Y.M., Zhou,F., Zhou,J.W., Liu,F., Zhou,S.Q., Li,B., Liu,Z.J. and Qin,Y.
    Aberrant Expressions of PSMD14 in Tumor Tissue are the Potential Prognostic Biomarkers for Hepatocellular Carcinoma after Curative Resection
    Curr Genomics24, 368-384. PubMed  Europe PubMed DOI
  16. Zhao,Z., Xu,H., Wei,Y., Sun,L. and Song,Y.
    Deubiquitylase PSMD14 inhibits autophagy to promote ovarian cancer progression via stabilization of LRPPRC
    Biochim Biophys Acta Mol Basis Dis1869, 166594-166594. PubMed  Europe PubMed DOI  K
    17. 2022
  17. Li,J., Li,Y., Xu,F., Sun,B., Yang,L. and Wang,H.
    Deubiquitinating enzyme PSMD14 facilitates gastric carcinogenesis through stabilizing PTBP1
    Exp Cell Res415, 113148-113148. PubMed  Europe PubMed DOI  K
  18. Luu,A.K., Cadieux,M., Wong,M., Macdonald,R., Jones,R., Choi,D., Oblak,M., Brisson,B., Sauer,S., Chafitz,J., Warshawsky,D., Wood,G.A. and Viloria-Petit,A.M.
    Proteomic Assessment of Extracellular Vesicles from Canine Tissue Explants as a Pipeline to Identify Molecular Targets in Osteosarcoma: PSMD14/Rpn11 as a Proof of Principle
    Int J Mol Sci23, PubMed  Europe PubMed DOI  I
  19. Schnoell,J., Scheiflinger,A., Al-Gboore,S., Kadletz-Wanke,L., Kenner,L., Heiduschka,G. and Jank,B.J.
    The prognostic role of PSMD14 in head and neck squamous cell carcinoma
    J Cancer Res Clin Oncol PubMed  Europe PubMed DOI
  20. Spataro,V. and Buetti-Dinh,A.
    POH1/Rpn11/PSMD14: a journey from basic research in fission yeast to a prognostic marker and a druggable target in cancer cells
    Br J Cancer PubMed  Europe PubMed DOI  I
  21. Yuan,Z., Hu,B., Xiao,H., Tan,X., Li,Y., Tang,K., Zhang,Y., Cai,K. and Ding,B.
    The E3 Ubiquitin Ligase RNF5 Facilitates SARS-CoV-2 Membrane Protein-Mediated Virion Release
    MBioe0316821-e0316821. PubMed  Europe PubMed DOI
    22. 2021
  22. Barban do Patrocinio,A., Cabral,F.J., de Paiva,T.H., Magalhaes,L.G., Paula,L.A.L., Brigato,O.M., Guerra-Sa,R. and Rodrigues,V.
    Deubiquitinating enzymes as possible drug targets for schistosomiasis
    Acta Trop217, 105856-105856. PubMed  Europe PubMed DOI  I
  23. Molho,M., Lin,W. and Nagy,P.D.
    A novel viral strategy for host factor recruitment: The co-opted proteasomal Rpn11 protein interaction hub in cooperation with subverted actin filaments are targeted to deliver cytosolic host factors for viral replication
    PLoS Pathog17, e1009680-e1009680. PubMed  Europe PubMed DOI  K
  24. Moon,S., Muniyappan,S., Lee,S.B. and Lee,B.H.
    Small-Molecule Inhibitors Targeting Proteasome-Associated Deubiquitinases
    Int J Mol Sci22, 6213-6213. PubMed  Europe PubMed DOI  I
    25. 2020
  25. Bustamante,H.A., Cereceda,K., Gonzalez,A.E., Valenzuela,G.E., Cheuquemilla,Y., Hernandez,S., Arias-Munoz,E., Cerda-Troncoso,C., Bandau,S., Soza,A., Kausel,G., Kerr,B., Mardones,G.A., Cancino,J., Hay,R.T., Rojas-Fernandez,A. and Burgos,P.V.
    The proteasomal deubiquitinating enzyme PSMD14 regulates macroautophagy by controlling golgi-to-er retrograde transport
    Cells9, PubMed  Europe PubMed DOI
  26. Chen,X., Dorris,Z., Shi,D., Huang,R.K., Khant,H., Fox,T., de Val,N., Williams,D., Zhang,P. and Walters,K.J.
    Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome
    Structure28, 1206-1217. PubMed  Europe PubMed DOI
  27. Lv,J., Zhang,S., Wu,H., Lu,J., Lu,Y., Wang,F., Zhao,W., Zhan,P., Lu,J., Fang,Q., Xie,C. and Yin,Z.
    Deubiquitinase PSMD14 enhances hepatocellular carcinoma growth and metastasis by stabilizing GRB2
    Cancer Lett469, 22-34. PubMed  Europe PubMed DOI
  28. Shin,J.Y., Muniyappan,S., Tran,N.N., Park,H., Lee,S.B. and Lee,B.H.
    Deubiquitination Reactions on the Proteasome for Proteasome Versatility
    Int J Mol Sci21, 5312-5312. PubMed  Europe PubMed DOI
  29. Yang,H.J., Asakawa,H., Ohtsuki,C., Haraguchi,T. and Hiraoka,Y.
    Transient Breakage of the Nucleocytoplasmic Barrier Controls Spore Maturation via Mobilizing the Proteasome Subunit Rpn11 in the Fission Yeast Schizosaccharomyces pombe
    J Fungi (Basel)6, 242-242. PubMed  Europe PubMed DOI
  30. Yokoyama,S., Iwakami,Y., Hang,Z., Kin,R., Zhou,Y., Yasuta,Y., Takahashi,A., Hayakawa,Y. and Sakurai,H.
    Targeting PSMD14 inhibits melanoma growth through SMAD3 stabilization
    Sci Rep10, 19214-19214. PubMed  Europe PubMed DOI  K
  31. Zhang,L., Xu,H., Ma,C., Zhang,J., Zhao,Y., Yang,X., Wang,S. and Li,D.
    Upregulation of deubiquitinase c in lung adenocarcinoma (LUAD) and its prognostic significance
    J Cancer11, 2962-2971. PubMed  Europe PubMed DOI
    32. 2019
  32. Bramasole,L., Sinha,A., Harshuk,D., Cirigliano,A., Gurevich,S., Yu,Z., Carmeli,R.L., Glickman,M.H., Rinaldi,T. and Pick,E.
    The proteasome lid triggers COP9 signalosome activity during the transition of Sachharomyces cerevisiae cells into quiescence
    Biomolecules9, 449-449. PubMed  Europe PubMed DOI  M
  33. Hameed,D.S., Sapmaz,A., Burggraaff,L., Amore,A., Slingerland,C.J., van Westen,G.J.P. and Ovaa,H.
    Development of ubiquitin-based probe for metalloprotease deubiquitinases
    Angew Chem Int Ed Engl58, 14477-14482. PubMed  Europe PubMed DOI
  34. Seo,D., Jung,S.M., Park,J.S., Lee,J., Ha,J., Kim,M. and Park,S.H.
    The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway
    EBioMedicine49, 55-71. PubMed  Europe PubMed DOI
  35. Wang,B., Xu,X., Yang,Z., Zhang,L., Liu,Y., Ma,A., Xu,G., Tang,M., Jing,T., Wu,L. and Liu,Y.
    POH1 contributes to hyperactivation of TGF-beta signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-beta receptors and caveolin-1
    EBioMedicine41, 320-332. PubMed  Europe PubMed DOI
  36. Zhi,T., Jiang,K., Xu,X., Yu,T., Zhou,F., Wang,Y., Liu,N. and Zhang,J.
    ECT2/PSMD14/PTTG1 axis promotes the proliferation of glioma through stabilizing E2F1
    Neuro Oncol21, 462-473. PubMed  Europe PubMed DOI
    37. 2018
  37. Kolog Gulko,M., Heinrich,G., Gross,C., Popova,B., Valerius,O., Neumann,P., Ficner,R. and Braus,G.H.
    Sem1 links proteasome stability and specificity to multicellular development
    PLoS Genet14, e1007141-e1007141. PubMed  Europe PubMed DOI
  38. Kumar,V., Naumann,M. and Stein,M.
    Computational Studies on the Inhibitor Selectivity of Human JAMM Deubiquitinylases Rpn11 and CSN5
    Front Chem6, 480-480. PubMed  Europe PubMed DOI  I
  39. Li,J., Zhang,Y., Da Silva Sil Dos Santos,B., Wang,F., Ma,Y., Perez,C., Yang,Y., Peng,J., Cohen,S.M., Chou,T.F., Hilton,S.T. and Deshaies,R.J.
    Epidithiodiketopiperazines inhibit protein degradation by targeting proteasome deubiquitinase Rpn11
    Cell Chem Biol25, 1350-1358. PubMed  Europe PubMed DOI  I
  40. Zhang,L., Liu,Y., Wang,B., Xu,G., Yang,Z., Tang,M., Ma,A., Jing,T., Xu,X., Zhang,X. and Liu,Y.
    POH1 deubiquitinates pro-interleukin-1beta and restricts inflammasome activity
    Nat Commun9, 4225-4225. PubMed  Europe PubMed DOI
    41. 2017
  41. Cohen,S.M.
    A bioinorganic approach to fragment-based drug discovery targeting metalloenzymes
    Acc Chem Res50, 2007-2016. PubMed  Europe PubMed DOI  I
  42. De Poot,S.A.H., Tian,G. and Finley,D.
    Meddling with fate: the proteasomal deubiquitinating enzymes
    J Mol Biol429, 3525-3545. PubMed  Europe PubMed DOI
  43. Lauinger,L., Li,J., Shostak,A., Cemel,I.A., Ha,N., Zhang,Y., Merkl,P.E., Obermeyer,S., Stankovic-Valentin,N., Schafmeier,T., Wever,W.J., Bowers,A.A., Carter,K.P., Palmer,A.E., Tschochner,H., Melchior,F., Deshaies,R.J., Brunner,M. and Diernfellner,A.
    Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases
    Nat Chem Biol13, 709-714. PubMed  Europe PubMed DOI  I
  44. Li,J., Yakushi,T., Parlati,F., Mackinnon,A.L., Perez,C., Ma,Y., Carter,K.P., Colayco,S., Magnuson,G., Brown,B., Nguyen,K., Vasile,S., Suyama,E., Smith,L.H., Sergienko,E., Pinkerton,A.B., Chung,T.D.Y., Palmer,A.E., Pass,I., Hess,S., Cohen,S.M. and Deshaies,R.J.
    Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11
    Nat Chem Biol13, 486-493. PubMed  Europe PubMed DOI  I
  45. Perez,C., Li,J., Parlati,F., Rouffet,M., Ma,Y., Mackinnon,A.L., Chou,T.F., Deshaies,R.J. and Cohen,S.M.
    Discovery of an inhibitor of the proteasome subunit Rpn11
    J Med Chem60, 1343-1361. PubMed  Europe PubMed DOI  I
  46. Song,Y., Li,S., Ray,A., Das,D.S., Qi,J., Samur,M.K., Tai,Y.T., Munshi,N., Carrasco,R.D., Chauhan,D. and Anderson,K.C.
    Blockade of deubiquitylating enzyme Rpn11 triggers apoptosis in multiple myeloma cells and overcomes bortezomib resistance
    Oncogene36, 5631-5638. PubMed  Europe PubMed DOI  I
  47. Worden,E.J., Dong,K.C. and Martin,A.
    An AAA motor-driven mechanical switch in Rpn11 controls deubiquitination at the 26S proteasome
    Mol Cell67, 799-811. PubMed  Europe PubMed DOI  S
    48. 2016
  48. Dambacher,C.M., Worden,E.J., Herzik,M.A., Martin,A. and Lander,G.C.
    Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition
    elife5, e13027-e13027. PubMed  Europe PubMed DOI  S
  49. Ronau,J.A., Beckmann,J.F. and Hochstrasser,M.
    Substrate specificity of the ubiquitin and Ubl proteases
    Cell Res26, 441-456. PubMed  Europe PubMed DOI
    50. 2015
  50. Mansour,W., Nakasone,M.A., von Delbruck,M., Yu,Z., Krutauz,D., Reis,N., Kleifeld,O., Sommer,T., Fushman,D. and Glickman,M.H.
    Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6
    J Biol Chem290, 4688-4704. PubMed  Europe PubMed DOI
  51. Prasanth,K.R., Barajas,D. and Nagy,P.D.
    The proteasomal Rpn11 metalloprotease suppresses tombusvirus RNA recombination and promotes viral replication via facilitating assembly of the viral replicase complex
    J Virol89, 2750-2763. PubMed  Europe PubMed DOI
    52. 2014
  52. Birol,M. and Echalier,A.
    Structure and function of MPN (Mpr1/Pad1 N-terminal) domain-containing proteins
    Curr Protein Pept Sci15, 504-517. PubMed  Europe PubMed DOI
  53. Kulichkova,V.A., Zaykova,Y.Y., Ermolaeva,Y.B., Vinogradova,E.V., Huang,L., Tomilin,A.N., Barlev,N.A. and Tsimokha,A.S.
    Creation of a HEK293 cell line stably expressing the proteasome subunit PSMD14 fused with fluorescent protein EGFP and HTBT tag
    Cell Tissue Biol8, 330-336. DOI  E
  54. Pathare,G.R., Nagy,I., Sledz,P., Anderson,D.J., Zhou,H.J., Pardon,E., Steyaert,J., Forster,F., Bracher,A. and Baumeister,W.
    Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11
    Proc Natl Acad Sci U S A111, 2984-2989. PubMed  Europe PubMed DOI  S
  55. Pick,E. and Bramasole,L.
    Moonlighting and pleiotropy within two regulators of the degradation machinery: the proteasome lid and the CSN
    Biochem Soc Trans42, 1786-1791. PubMed  Europe PubMed DOI
  56. Wauer,T. and Komander,D.
    The JAMM in the proteasome
    Nat Struct Mol Biol21, 346-348. PubMed  Europe PubMed DOI
  57. Worden,E.J., Padovani,C. and Martin,A.
    Structure of the Rpn11-Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradation
    Nat Struct Mol Biol21, 220-227. PubMed  Europe PubMed DOI  S
    58. 2013
  58. Matyskiela,M.E., Lander,G.C. and Martin,A.
    Conformational switching of the 26S proteasome enables substrate degradation
    Nat Struct Mol Biol20, 781-788. PubMed  Europe PubMed DOI  S
    59. 2012
  59. Butler,L.R., Densham,R.M., Jia,J., Garvin,A.J., Stone,H.R., Shah,V., Weekes,D., Festy,F., Beesley,J. and Morris,J.R.
    The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response
    EMBO J31, 3918-3934. PubMed  Europe PubMed DOI
  60. Livnat-Levanon,N., Glaser,F. and Glickman,M.H.
    Poh1 peptidase
    [ISSN:978-0-12-407743-0]3, 1560-1566. DOI
    61. 2011
  61. Lee,M.J., Lee,B.H., Hanna,J., King,R.W. and Finley,D.
    Trimming of ubiquitin chains by proteasome-associated deubiquitinating enzymes
    Mol Cell Proteomics10, R110-R110. PubMed  Europe PubMed DOI  P
    62. 2010
  62. Byrne,A., McLaren,R.P., Mason,P., Chai,L., Dufault,M.R., Huang,Y., Liang,B., Gans,J.D., Zhang,M., Carter,K., Gladysheva,T.B., Teicher,B.A., Biemann,H.P., Booker,M., Goldberg,M.A., Klinger,K.W., Lillie,J., Madden,S.L. and Jiang,Y.
    Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence
    Exp Cell Res316, 258-271. PubMed  Europe PubMed DOI
  63. Chandra,A., Chen,L. and Madura,K.
    Synthetic lethality of rpn11-1 rpn10Delta is linked to altered proteasome assembly and activity
    Curr Genet56, 543-557. PubMed  Europe PubMed DOI  K
  64. Chandra,A., Chen,L., Liang,H. and Madura,K.
    Proteasome assembly influences interaction with ubiquitinated proteins and shuttle factors
    J Biol Chem285, 8330-8339. PubMed  Europe PubMed DOI
    65. 2009
  65. Cooper,E.M., Cutcliffe,C., Kristiansen,T.Z., Pandey,A., Pickart,C.M. and Cohen,R.E.
    K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1
    EMBO J28, 621-631. PubMed  Europe PubMed DOI
  66. Tonoki,A., Kuranaga,E., Tomioka,T., Hamazaki,J., Murata,S., Tanaka,K. and Miura,M.
    Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process
    Mol Cell Biol29, 1095-1106. PubMed  Europe PubMed DOI
    67. 2008
  67. Koulich,E., Li,X. and DeMartino,G.N.
    Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome
    Mol Biol Cell19, 1072-1082. PubMed  Europe PubMed DOI
  68. Rinaldi,T., Hofmann,L., Gambadoro,A., Cossard,R., Livnat-Levanon,N., Glickman,M.H., Frontali,L. and Delahodde,A.
    Dissection of the carboxyl-terminal domain of the proteasomal subunit Rpn11 in maintenance of mitochondrial structure and function
    Mol Biol Cell19, 1022-1031. PubMed  Europe PubMed DOI
    69. 2007
  69. Gallery,M., Blank,J.L., Lin,Y., Gutierrez,J.A., Pulido,J.C., Rappoli,D., Badola,S., Rolfe,M. and Macbeth,K.J.
    The JAMM motif of human deubiquitinase Poh1 is essential for cell viability
    Mol Cancer Ther6, 262-268. PubMed  Europe PubMed DOI
    70. 2006
  70. [YEAR:6-10-2006]Hanna,J., Hathaway,N.A., Tone,Y., Crosas,B., Elsasser,S., Kirkpatrick,D.S., Leggett,D.S., Gygi,S.P., King,R.W. and Finley,D.
    Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation
    Cell127, 99-111. PubMed  Europe PubMed DOI
    71. 2004
  71. Guterman,A. and Glickman,M.H.
    Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome
    J Biol Chem279, 1729-1738. PubMed  Europe PubMed DOI
  72. [YEAR:1-7-2004]Rinaldi,T., Pick,E., Gambadoro,A., Zilli,S., Maytal-Kivity,V., Frontali,L. and Glickman,M.H.
    Participation of the proteasomal lid subunit Rpn11 in mitochondrial morphology and function is mapped to a distinct C-terminal domain
    Biochem J381, 275-285. PubMed  Europe PubMed DOI
    73. 2003
  73. Lundgren,J., Masson,P., Realini,C.A. and Young,P.
    Use of RNA interference and complementation to study the function of the Drosophila and human 26S proteasome subunit S13
    Mol Cell Biol23, 5320-5330. PubMed  Europe PubMed DOI
    74. 2002
  74. [YEAR:20-9-2002]Maytal-Kivity,V., Reis,N., Hofmann,K. and Glickman,M.H.
    MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function
    BMC Biochem3, 28-28. PubMed  Europe PubMed
  75. [YEAR:30-4-2002]Nabhan,J.F., Hamdan,F.F. and Ribeiro,P.
    A Schistosoma mansoni Pad1 homologue stabilizes c-Jun
    Mol Biochem Parasitol121, 163-172. PubMed  Europe PubMed
  76. [YEAR:6-3-2002]Rinaldi,T., Ricordy,R., Bolotin-Fukuhara,M. and Frontali,L.
    Mitochondrial effects of the pleiotropic proteasomal mutation mpr1/rpn11: uncoupling from cell cycle defects in extragenic revertants
    Gene286, 43-51. PubMed  Europe PubMed DOI
  77. Spataro,V., Simmen,K. and Realini,C.A.
    The essential 26S proteasome subunit Rpn11 confers multidrug resistance to mammalian cells
    Anticancer Res22, 3905-3909. PubMed  Europe PubMed
  78. [YEAR:18-10-2002]Verma,R., Aravind,L., Oania,R., McDonald,W.H., Yates,J.R., III, Koonin,E.V. and Deshaies,R.J.
    Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome
    Science298, 611-615. PubMed  Europe PubMed DOI
  79. [YEAR:26-9-2002]Wilkinson,K.D.
    Cell biology: unchaining the condemned
    Nature419, 351-353. PubMed  Europe PubMed DOI
  80. [YEAR:26-9-2002]Yao,T. and Cohen,R.E.
    A cryptic protease couples deubiquitination and degradation by the proteasome
    Nature419, 403-407. PubMed  Europe PubMed DOI
    81. 2001
  81. Krasko,A., Kurelec,B., Batel,R., Muller,I.M. and Muller,W.E.
    Potential multidrug resistance gene POHL: an ecologically relevant indicator in marine sponges
    Environ Toxicol Chem20, 198-204. PubMed  Europe PubMed
    82. 1999
  82. [YEAR:29-9-1999]Wilkinson,C.R., Penney,M., McGurk,G., Wallace,M. and Gordon,C.
    The 26S proteasome of the fission yeast Schizosaccharomyces pombe
    Philos Trans R Soc Lond B Biol Sci354, 1523-1532. PubMed  Europe PubMed DOI
    83. 1998
  83. Arioka,M., Kouhashi,M., Yoda,K., Takatsuki,A., Yamasaki,M. and Kitamoto,K.
    Multidrug resistance phenotype conferred by overexpressing bfr2+/pad1+/sks1+ or pap1+ genes and mediated by bfr1+ gene product, a structural and functional homologue of P-glycoprotein in Schizosaccharomyces pombe
    Biosci Biotechnol Biochem62, 390-392. PubMed  Europe PubMed DOI
  84. Glickman,M.H., Rubin,D.M., Fried,V.A. and Finley,D.
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