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Literature for peptidase M67.001: PSMD14 peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, M Mutation, P Specificity, I Inhibitor, K Knockout, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Eibach,Y., Kreher,S., Poetsch,M.S., Kho,A.L., Gaertner,U., Clemen,C.S., Schroder,R., Guo,K., Milting,H., Meder,B., Potente,M., Richter,M., Schneider,A., Meiners,S., Gaute,M. and Braun,T.
    The deubiquitinase USP5 prevents accumulation of protein aggregates in cardiomyocytes
    Sci Adv (2025) 11, eado3852-eado3852. PubMed  Europe PubMed DOI  PMC  EPMC
  2. Gao,J., Nardone,C., Yip,M.C.J., Chino,H., Gu,X., Mirman,Z., Rale,M.J., Paulo,J.A., Elledge,S.J. and Shao,S.
    Structure of the TXNL1-bound proteasome
    Nat Struct Mol Biol (2025) PubMed  Europe PubMed DOI
  3. Lu,J., Wu,H., Zhan,P., Lu,Y., Fang,Q., Luo,C., Wang,F., Wen,J., Xie,C. and Yin,Z.
    PSMD14-mediated deubiquitination of CARM1 facilitates the proliferation and metastasis of hepatocellular carcinoma by inducing the transcriptional activation of FERMT1
    Cell Death Dis (2025) 16, 141-141. PubMed  Europe PubMed DOI  PMC  EPMC
  4. Lu,R.S., Ren,L.K., Fei,X.B., Liu,S.B., Gao,Y.J., Hou,J.Y., Wang,C., Liu,P., Zhu,C.H., Wang,X. and Pan,Y.Z.
    PSMD14-Mediated LDHA Deubiquitination Upregulates ACLY Expression via H3K18 Lactylation to Promote Lipid Synthesis and Pancreatic Cancer Progression
    Adv Sci (Weinh) (2025) , e05762-e05762. PubMed  Europe PubMed DOI
  5. Peddada,N., Zhong,X., Yin,Y., Lazaro,D.R., Wang,J., Lyon,S., Choi,J.H., Bai,X.C., Moresco,E.M.Y. and Beutler,B.
    Structural insights into the ubiquitin-independent midnolin-proteasome pathway
    Proc Natl Acad Sci U S A (2025) 122, e2505345122-e2505345122. PubMed  Europe PubMed DOI
    6. 2024
  6. Arkinson,C., Gee,C.L., Zhang,Z., Dong,K.C. and Martin,A.
    Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1
    bioRxiv (2024) PubMed  Europe PubMed DOI  PMC  EPMC
  7. Guo,X., Mutch,M., Torres,A.Y., Nano,M., Rauth,N., Harwood,J., McDonald,D., Chen,Z., Montell,C., Dai,W. and Montell,D.J.
    The Zn(2+) transporter ZIP7 enhances endoplasmic-reticulum-associated protein degradation and prevents neurodegeneration in Drosophila
    Dev Cell (2024) 59, 1655-1667. PubMed  Europe PubMed DOI
  8. Htet,Z.M., Dong,K.C. and Martin,A.
    The deubiquitinase Rpn11 functions as an allosteric ubiquitin sensor to promote substrate engagement by the 26S proteasome
    bioRxiv (2024) PubMed  Europe PubMed DOI  PMC  EPMC
  9. Lai,J., Kong,W., Fu,Q., Jiang,Z., Sun,B., Ye,X., Kong,J., Wei,S. and Jiang,L.
    PSMD14 is a novel prognostic marker and therapeutic target in osteosarcoma
    Diagn Pathol (2024) 19, 79-79. PubMed  Europe PubMed DOI  PMC  EPMC  K
  10. Yang,P., Yang,X., Wang,D., Yang,H., Li,Z., Zhang,C., Zhang,S., Zhu,J., Li,X., Su,P. and Zhuang,T.
    PSMD14 stabilizes estrogen signaling and facilitates breast cancer progression via deubiquitinating ERalpha
    Oncogene (2024) 43, 248-264. PubMed  Europe PubMed DOI  PMC  EPMC  K
  11. Yuan,Y., Li,Y., Wu,X., Bo,J., Zhang,L., Zhang,J., Hu,Y., Chen,Y., Zeng,Y., Wei,X. and Zhang,H.
    POH1 induces Smad3 deubiquitination and promotes lung cancer metastasis
    Cancer Lett (2024) 582, 216526-216526. PubMed  Europe PubMed DOI
  12. Zhou,B., Luo,Y., Bi,H., Zhang,N., Ma,M., Dong,Z., Ji,N., Zhang,S., Wang,X., Liu,Y., Guo,X., Wei,W., Xie,C., Wu,L., Wan,X., Zheng,M.H., Zhao,B., Li,Y., Hu,C. and Lu,Y.
    Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
    Cell Metab (2024) 36, 2228-2244. PubMed  Europe PubMed DOI
    13. 2023
  13. Bustamante,H.A., Albornoz,N., Morselli,E., Soza,A. and Burgos,P.V.
    Novel insights into the non-canonical roles of PSMD14/POH1/Rpn11 in proteostasis and in the modulation of cancer progression
    Cell Signal (2023) 101, 110490-110490. PubMed  Europe PubMed DOI
  14. Guo,X., Mutch,M., Torres,A.Y., Nano,M., McDonald,D., Chen,Z., Montell,C., Dai,W. and Montell,D.J.
    Rescue of proteotoxic stress and neurodegeneration by the Zn (2+) transporter ZIP7
    bioRxiv (2023) PubMed  Europe PubMed DOI  PMC  EPMC
  15. Jing,T., Xu,X., Wu,C., Wei,D., Yuan,L., Huang,Y., Liu,Y. and Wang,B.
    POH1 facilitates pancreatic carcinogenesis through MYC-driven acinar-to-ductal metaplasia and is a potential therapeutic target
    Cancer Lett (2023) 577, 216444-216444. PubMed  Europe PubMed DOI
  16. Liu,Z., Wang,X., Li,C. and Zhao,R.
    The function and mechanism of PSMD14 in promoting progression and resistance to anlotinib in osteosarcoma
    Cancer Cell Int (2023) 23, 309-309. PubMed  Europe PubMed DOI  PMC  EPMC  K
  17. Xie,G., Dong,K.C., Worden,E.J. and Martin,A.
    High-Throughput Assay for Characterizing Rpn11 Deubiquitinase Activity
    Methods Mol Biol (2023) 2591, 79-100. PubMed  Europe PubMed DOI
  18. Xiong,Y.M., Zhou,F., Zhou,J.W., Liu,F., Zhou,S.Q., Li,B., Liu,Z.J. and Qin,Y.
    Aberrant Expressions of PSMD14 in Tumor Tissue are the Potential Prognostic Biomarkers for Hepatocellular Carcinoma after Curative Resection
    Curr Genomics (2023) 24, 368-384. PubMed  Europe PubMed DOI  PMC  EPMC
  19. Zhao,Z., Xu,H., Wei,Y., Sun,L. and Song,Y.
    Deubiquitylase PSMD14 inhibits autophagy to promote ovarian cancer progression via stabilization of LRPPRC
    Biochim Biophys Acta Mol Basis Dis (2023) 1869, 166594-166594. PubMed  Europe PubMed DOI  K
    20. 2022
  20. Li,J., Li,Y., Xu,F., Sun,B., Yang,L. and Wang,H.
    Deubiquitinating enzyme PSMD14 facilitates gastric carcinogenesis through stabilizing PTBP1
    Exp Cell Res (2022) 415, 113148-113148. PubMed  Europe PubMed DOI  K
  21. Luu,A.K., Cadieux,M., Wong,M., Macdonald,R., Jones,R., Choi,D., Oblak,M., Brisson,B., Sauer,S., Chafitz,J., Warshawsky,D., Wood,G.A. and Viloria-Petit,A.M.
    Proteomic Assessment of Extracellular Vesicles from Canine Tissue Explants as a Pipeline to Identify Molecular Targets in Osteosarcoma: PSMD14/Rpn11 as a Proof of Principle
    Int J Mol Sci (2022) 23 PubMed  Europe PubMed DOI  PMC  EPMC  I
  22. Schnoell,J., Scheiflinger,A., Al-Gboore,S., Kadletz-Wanke,L., Kenner,L., Heiduschka,G. and Jank,B.J.
    The prognostic role of PSMD14 in head and neck squamous cell carcinoma
    J Cancer Res Clin Oncol (2022) PubMed  Europe PubMed DOI
  23. Spataro,V. and Buetti-Dinh,A.
    POH1/Rpn11/PSMD14: a journey from basic research in fission yeast to a prognostic marker and a druggable target in cancer cells
    Br J Cancer (2022) PubMed  Europe PubMed DOI  I
  24. Yuan,Z., Hu,B., Xiao,H., Tan,X., Li,Y., Tang,K., Zhang,Y., Cai,K. and Ding,B.
    The E3 Ubiquitin Ligase RNF5 Facilitates SARS-CoV-2 Membrane Protein-Mediated Virion Release
    MBio (2022) , e0316821-e0316821. PubMed  Europe PubMed DOI  PMC  EPMC
    25. 2021
  25. Barban do Patrocinio,A., Cabral,F.J., de Paiva,T.H., Magalhaes,L.G., Paula,L.A.L., Brigato,O.M., Guerra-Sa,R. and Rodrigues,V.
    Deubiquitinating enzymes as possible drug targets for schistosomiasis
    Acta Trop (2021) 217, 105856-105856. PubMed  Europe PubMed DOI  I
  26. Molho,M., Lin,W. and Nagy,P.D.
    A novel viral strategy for host factor recruitment: The co-opted proteasomal Rpn11 protein interaction hub in cooperation with subverted actin filaments are targeted to deliver cytosolic host factors for viral replication
    PLoS Pathog (2021) 17, e1009680-e1009680. PubMed  Europe PubMed DOI  PMC  EPMC  K
  27. Moon,S., Muniyappan,S., Lee,S.B. and Lee,B.H.
    Small-Molecule Inhibitors Targeting Proteasome-Associated Deubiquitinases
    Int J Mol Sci (2021) 22, 6213-6213. PubMed  Europe PubMed DOI  PMC  EPMC  I
    28. 2020
  28. Bustamante,H.A., Cereceda,K., Gonzalez,A.E., Valenzuela,G.E., Cheuquemilla,Y., Hernandez,S., Arias-Munoz,E., Cerda-Troncoso,C., Bandau,S., Soza,A., Kausel,G., Kerr,B., Mardones,G.A., Cancino,J., Hay,R.T., Rojas-Fernandez,A. and Burgos,P.V.
    The proteasomal deubiquitinating enzyme PSMD14 regulates macroautophagy by controlling golgi-to-er retrograde transport
    Cells (2020) 9 PubMed  Europe PubMed DOI
  29. Chen,X., Dorris,Z., Shi,D., Huang,R.K., Khant,H., Fox,T., de Val,N., Williams,D., Zhang,P. and Walters,K.J.
    Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome
    Structure (2020) 28, 1206-1217. PubMed  Europe PubMed DOI
  30. Lv,J., Zhang,S., Wu,H., Lu,J., Lu,Y., Wang,F., Zhao,W., Zhan,P., Lu,J., Fang,Q., Xie,C. and Yin,Z.
    Deubiquitinase PSMD14 enhances hepatocellular carcinoma growth and metastasis by stabilizing GRB2
    Cancer Lett (2020) 469, 22-34. PubMed  Europe PubMed DOI
  31. Shin,J.Y., Muniyappan,S., Tran,N.N., Park,H., Lee,S.B. and Lee,B.H.
    Deubiquitination Reactions on the Proteasome for Proteasome Versatility
    Int J Mol Sci (2020) 21, 5312-5312. PubMed  Europe PubMed DOI
  32. Yang,H.J., Asakawa,H., Ohtsuki,C., Haraguchi,T. and Hiraoka,Y.
    Transient Breakage of the Nucleocytoplasmic Barrier Controls Spore Maturation via Mobilizing the Proteasome Subunit Rpn11 in the Fission Yeast Schizosaccharomyces pombe
    J Fungi (Basel) (2020) 6, 242-242. PubMed  Europe PubMed DOI
  33. Yokoyama,S., Iwakami,Y., Hang,Z., Kin,R., Zhou,Y., Yasuta,Y., Takahashi,A., Hayakawa,Y. and Sakurai,H.
    Targeting PSMD14 inhibits melanoma growth through SMAD3 stabilization
    Sci Rep (2020) 10, 19214-19214. PubMed  Europe PubMed DOI  PMC  EPMC  K
  34. Zhang,L., Xu,H., Ma,C., Zhang,J., Zhao,Y., Yang,X., Wang,S. and Li,D.
    Upregulation of deubiquitinase c in lung adenocarcinoma (LUAD) and its prognostic significance
    J Cancer (2020) 11, 2962-2971. PubMed  Europe PubMed DOI  PMC  EPMC
    35. 2019
  35. Bramasole,L., Sinha,A., Harshuk,D., Cirigliano,A., Gurevich,S., Yu,Z., Carmeli,R.L., Glickman,M.H., Rinaldi,T. and Pick,E.
    The proteasome lid triggers COP9 signalosome activity during the transition of Sachharomyces cerevisiae cells into quiescence
    Biomolecules (2019) 9, 449-449. PubMed  Europe PubMed DOI  M
  36. Hameed,D.S., Sapmaz,A., Burggraaff,L., Amore,A., Slingerland,C.J., van Westen,G.J.P. and Ovaa,H.
    Development of ubiquitin-based probe for metalloprotease deubiquitinases
    Angew Chem Int Ed Engl (2019) 58, 14477-14482. PubMed  Europe PubMed DOI
  37. Seo,D., Jung,S.M., Park,J.S., Lee,J., Ha,J., Kim,M. and Park,S.H.
    The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway
    EBioMedicine (2019) 49, 55-71. PubMed  Europe PubMed DOI
  38. Wang,B., Xu,X., Yang,Z., Zhang,L., Liu,Y., Ma,A., Xu,G., Tang,M., Jing,T., Wu,L. and Liu,Y.
    POH1 contributes to hyperactivation of TGF-beta signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-beta receptors and caveolin-1
    EBioMedicine (2019) 41, 320-332. PubMed  Europe PubMed DOI
  39. Zhi,T., Jiang,K., Xu,X., Yu,T., Zhou,F., Wang,Y., Liu,N. and Zhang,J.
    ECT2/PSMD14/PTTG1 axis promotes the proliferation of glioma through stabilizing E2F1
    Neuro Oncol (2019) 21, 462-473. PubMed  Europe PubMed DOI
    40. 2018
  40. Kolog Gulko,M., Heinrich,G., Gross,C., Popova,B., Valerius,O., Neumann,P., Ficner,R. and Braus,G.H.
    Sem1 links proteasome stability and specificity to multicellular development
    PLoS Genet (2018) 14, e1007141-e1007141. PubMed  Europe PubMed DOI
  41. Kumar,V., Naumann,M. and Stein,M.
    Computational Studies on the Inhibitor Selectivity of Human JAMM Deubiquitinylases Rpn11 and CSN5
    Front Chem (2018) 6, 480-480. PubMed  Europe PubMed DOI  PMC  EPMC  I
  42. Li,J., Zhang,Y., Da Silva Sil Dos Santos,B., Wang,F., Ma,Y., Perez,C., Yang,Y., Peng,J., Cohen,S.M., Chou,T.F., Hilton,S.T. and Deshaies,R.J.
    Epidithiodiketopiperazines inhibit protein degradation by targeting proteasome deubiquitinase Rpn11
    Cell Chem Biol (2018) 25, 1350-1358. PubMed  Europe PubMed DOI  I
  43. Zhang,L., Liu,Y., Wang,B., Xu,G., Yang,Z., Tang,M., Ma,A., Jing,T., Xu,X., Zhang,X. and Liu,Y.
    POH1 deubiquitinates pro-interleukin-1beta and restricts inflammasome activity
    Nat Commun (2018) 9, 4225-4225. PubMed  Europe PubMed DOI  PMC  EPMC
    44. 2017
  44. Cohen,S.M.
    A bioinorganic approach to fragment-based drug discovery targeting metalloenzymes
    Acc Chem Res (2017) 50, 2007-2016. PubMed  Europe PubMed DOI  I
  45. De Poot,S.A.H., Tian,G. and Finley,D.
    Meddling with fate: the proteasomal deubiquitinating enzymes
    J Mol Biol (2017) 429, 3525-3545. PubMed  Europe PubMed DOI
  46. Lauinger,L., Li,J., Shostak,A., Cemel,I.A., Ha,N., Zhang,Y., Merkl,P.E., Obermeyer,S., Stankovic-Valentin,N., Schafmeier,T., Wever,W.J., Bowers,A.A., Carter,K.P., Palmer,A.E., Tschochner,H., Melchior,F., Deshaies,R.J., Brunner,M. and Diernfellner,A.
    Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases
    Nat Chem Biol (2017) 13, 709-714. PubMed  Europe PubMed DOI  I
  47. Li,J., Yakushi,T., Parlati,F., Mackinnon,A.L., Perez,C., Ma,Y., Carter,K.P., Colayco,S., Magnuson,G., Brown,B., Nguyen,K., Vasile,S., Suyama,E., Smith,L.H., Sergienko,E., Pinkerton,A.B., Chung,T.D.Y., Palmer,A.E., Pass,I., Hess,S., Cohen,S.M. and Deshaies,R.J.
    Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11
    Nat Chem Biol (2017) 13, 486-493. PubMed  Europe PubMed DOI  I
  48. Perez,C., Li,J., Parlati,F., Rouffet,M., Ma,Y., Mackinnon,A.L., Chou,T.F., Deshaies,R.J. and Cohen,S.M.
    Discovery of an inhibitor of the proteasome subunit Rpn11
    J Med Chem (2017) 60, 1343-1361. PubMed  Europe PubMed DOI  I
  49. Song,Y., Li,S., Ray,A., Das,D.S., Qi,J., Samur,M.K., Tai,Y.T., Munshi,N., Carrasco,R.D., Chauhan,D. and Anderson,K.C.
    Blockade of deubiquitylating enzyme Rpn11 triggers apoptosis in multiple myeloma cells and overcomes bortezomib resistance
    Oncogene (2017) 36, 5631-5638. PubMed  Europe PubMed DOI  I
  50. Worden,E.J., Dong,K.C. and Martin,A.
    An AAA motor-driven mechanical switch in Rpn11 controls deubiquitination at the 26S proteasome
    Mol Cell (2017) 67, 799-811. PubMed  Europe PubMed DOI  S
    51. 2016
  51. Dambacher,C.M., Worden,E.J., Herzik,M.A., Martin,A. and Lander,G.C.
    Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition
    elife (2016) 5, e13027-e13027. PubMed  Europe PubMed DOI  S
  52. Ronau,J.A., Beckmann,J.F. and Hochstrasser,M.
    Substrate specificity of the ubiquitin and Ubl proteases
    Cell Res (2016) 26, 441-456. PubMed  Europe PubMed DOI
    53. 2015
  53. Mansour,W., Nakasone,M.A., von Delbruck,M., Yu,Z., Krutauz,D., Reis,N., Kleifeld,O., Sommer,T., Fushman,D. and Glickman,M.H.
    Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6
    J Biol Chem (2015) 290, 4688-4704. PubMed  Europe PubMed DOI
  54. Prasanth,K.R., Barajas,D. and Nagy,P.D.
    The proteasomal Rpn11 metalloprotease suppresses tombusvirus RNA recombination and promotes viral replication via facilitating assembly of the viral replicase complex
    J Virol (2015) 89, 2750-2763. PubMed  Europe PubMed DOI
    55. 2014
  55. Birol,M. and Echalier,A.
    Structure and function of MPN (Mpr1/Pad1 N-terminal) domain-containing proteins
    Curr Protein Pept Sci (2014) 15, 504-517. PubMed  Europe PubMed DOI
  56. Kulichkova,V.A., Zaykova,Y.Y., Ermolaeva,Y.B., Vinogradova,E.V., Huang,L., Tomilin,A.N., Barlev,N.A. and Tsimokha,A.S.
    Creation of a HEK293 cell line stably expressing the proteasome subunit PSMD14 fused with fluorescent protein EGFP and HTBT tag
    Cell Tissue Biol (2014) 8, 330-336. DOI  E
  57. Pathare,G.R., Nagy,I., Sledz,P., Anderson,D.J., Zhou,H.J., Pardon,E., Steyaert,J., Forster,F., Bracher,A. and Baumeister,W.
    Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11
    Proc Natl Acad Sci U S A (2014) 111, 2984-2989. PubMed  Europe PubMed DOI  S
  58. Pick,E. and Bramasole,L.
    Moonlighting and pleiotropy within two regulators of the degradation machinery: the proteasome lid and the CSN
    Biochem Soc Trans (2014) 42, 1786-1791. PubMed  Europe PubMed DOI
  59. Wauer,T. and Komander,D.
    The JAMM in the proteasome
    Nat Struct Mol Biol (2014) 21, 346-348. PubMed  Europe PubMed DOI
  60. Worden,E.J., Padovani,C. and Martin,A.
    Structure of the Rpn11-Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradation
    Nat Struct Mol Biol (2014) 21, 220-227. PubMed  Europe PubMed DOI  S
    61. 2013
  61. Matyskiela,M.E., Lander,G.C. and Martin,A.
    Conformational switching of the 26S proteasome enables substrate degradation
    Nat Struct Mol Biol (2013) 20, 781-788. PubMed  Europe PubMed DOI  S
    62. 2012
  62. Butler,L.R., Densham,R.M., Jia,J., Garvin,A.J., Stone,H.R., Shah,V., Weekes,D., Festy,F., Beesley,J. and Morris,J.R.
    The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response
    EMBO J (2012) 31, 3918-3934. PubMed  Europe PubMed DOI
  63. Livnat-Levanon,N., Glaser,F. and Glickman,M.H.
    Poh1 peptidase
    [ISSN:978-0-12-407743-0] (2012) 3, 1560-1566. DOI
    64. 2011
  64. Lee,M.J., Lee,B.H., Hanna,J., King,R.W. and Finley,D.
    Trimming of ubiquitin chains by proteasome-associated deubiquitinating enzymes
    Mol Cell Proteomics (2011) 10, R110-R110. PubMed  Europe PubMed DOI  P
    65. 2010
  65. Byrne,A., McLaren,R.P., Mason,P., Chai,L., Dufault,M.R., Huang,Y., Liang,B., Gans,J.D., Zhang,M., Carter,K., Gladysheva,T.B., Teicher,B.A., Biemann,H.P., Booker,M., Goldberg,M.A., Klinger,K.W., Lillie,J., Madden,S.L. and Jiang,Y.
    Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence
    Exp Cell Res (2010) 316, 258-271. PubMed  Europe PubMed DOI
  66. Chandra,A., Chen,L. and Madura,K.
    Synthetic lethality of rpn11-1 rpn10Delta is linked to altered proteasome assembly and activity
    Curr Genet (2010) 56, 543-557. PubMed  Europe PubMed DOI  K
  67. Chandra,A., Chen,L., Liang,H. and Madura,K.
    Proteasome assembly influences interaction with ubiquitinated proteins and shuttle factors
    J Biol Chem (2010) 285, 8330-8339. PubMed  Europe PubMed DOI  PMC  EPMC
    68. 2009
  68. Cooper,E.M., Cutcliffe,C., Kristiansen,T.Z., Pandey,A., Pickart,C.M. and Cohen,R.E.
    K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1
    EMBO J (2009) 28, 621-631. PubMed  Europe PubMed DOI  PMC  EPMC
  69. Tonoki,A., Kuranaga,E., Tomioka,T., Hamazaki,J., Murata,S., Tanaka,K. and Miura,M.
    Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process
    Mol Cell Biol (2009) 29, 1095-1106. PubMed  Europe PubMed DOI  PMC  EPMC
    70. 2008
  70. Koulich,E., Li,X. and DeMartino,G.N.
    Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome
    Mol Biol Cell (2008) 19, 1072-1082. PubMed  Europe PubMed DOI  PMC  EPMC
  71. Rinaldi,T., Hofmann,L., Gambadoro,A., Cossard,R., Livnat-Levanon,N., Glickman,M.H., Frontali,L. and Delahodde,A.
    Dissection of the carboxyl-terminal domain of the proteasomal subunit Rpn11 in maintenance of mitochondrial structure and function
    Mol Biol Cell (2008) 19, 1022-1031. PubMed  Europe PubMed DOI  PMC  EPMC
    72. 2007
  72. Gallery,M., Blank,J.L., Lin,Y., Gutierrez,J.A., Pulido,J.C., Rappoli,D., Badola,S., Rolfe,M. and Macbeth,K.J.
    The JAMM motif of human deubiquitinase Poh1 is essential for cell viability
    Mol Cancer Ther (2007) 6, 262-268. PubMed  Europe PubMed DOI
    73. 2006
  73. [YEAR:6-10-2006]Hanna,J., Hathaway,N.A., Tone,Y., Crosas,B., Elsasser,S., Kirkpatrick,D.S., Leggett,D.S., Gygi,S.P., King,R.W. and Finley,D.
    Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation
    Cell (6-10-2006) 127, 99-111. PubMed  Europe PubMed DOI
    74. 2004
  74. Guterman,A. and Glickman,M.H.
    Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome
    J Biol Chem (2004) 279, 1729-1738. PubMed  Europe PubMed DOI
  75. [YEAR:1-7-2004]Rinaldi,T., Pick,E., Gambadoro,A., Zilli,S., Maytal-Kivity,V., Frontali,L. and Glickman,M.H.
    Participation of the proteasomal lid subunit Rpn11 in mitochondrial morphology and function is mapped to a distinct C-terminal domain
    Biochem J (1-7-2004) 381, 275-285. PubMed  Europe PubMed DOI  PMC  EPMC
    76. 2003
  76. Lundgren,J., Masson,P., Realini,C.A. and Young,P.
    Use of RNA interference and complementation to study the function of the Drosophila and human 26S proteasome subunit S13
    Mol Cell Biol (2003) 23, 5320-5330. PubMed  Europe PubMed DOI  PMC  EPMC
    77. 2002
  77. [YEAR:20-9-2002]Maytal-Kivity,V., Reis,N., Hofmann,K. and Glickman,M.H.
    MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function
    BMC Biochem (20-9-2002) 3, 28-28. PubMed  Europe PubMed  PMC  EPMC
  78. [YEAR:30-4-2002]Nabhan,J.F., Hamdan,F.F. and Ribeiro,P.
    A Schistosoma mansoni Pad1 homologue stabilizes c-Jun
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