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Literature for peptidase M66.001: StcE peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature

(Topics flags: T Target, P Specificity, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Merkl,P., Vuksinic,I., Archer,C., Leroux,J.C. and Steiger,M.B.
    Overcoming the gastrointestinal mucus barrier: Zinc-dependent modulation of mucinase activity
    Int J Pharm (2026) 688, 126445-126445. PubMed  Europe PubMed DOI
    2. 2024
  2. Feldmuller,M., Ericson,C.F., Afanasyev,P., Lien,Y.W., Weiss,G.L., Wollweber,F., Schoof,M., Hurst,M. and Pilhofer,M.
    Stepwise assembly and release of Tc toxins from Yersinia entomophaga
    Nat Microbiol (2024) 9, 405-420. PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2022
  3. Riley,N.M. and Bertozzi,C.R.
    Deciphering O-glycoprotease substrate preferences with O-Pair Search
    Mol Omics (2022) 18, 908-922. PubMed  Europe PubMed DOI  PMC  EPMC
    4. 2019
  4. Malaker,S.A., Pedram,K., Ferracane,M.J., Bensing,B.A., Krishnan,V., Pett,C., Yu,J., Woods,E.C., Kramer,J.R., Westerlind,U., Dorigo,O. and Bertozzi,C.R.
    The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
    Proc Natl Acad Sci U S A (2019) 116, 7278-7287. PubMed  Europe PubMed DOI
    5. 2018
  5. Furniss,R.C.D., Low,W.W., Mavridou,D.A.I., Dagley,L.F., Webb,A.I., Tate,E.W. and Clements,A.
    Plasma membrane profiling during enterohemorrhagic E. coli infection reveals that the metalloprotease StcE cleaves CD55 from host epithelial surfaces
    J Biol Chem (2018) 293, 17188-17199. PubMed  Europe PubMed DOI
    6. 2017
  6. Hews,C.L., Tran,S.L., Wegmann,U., Brett,B., Walsham,A.D., Kavanaugh,D., Ward,N.J., Juge,N. and Schuller,S.
    The StcE metalloprotease of enterohaemorrhagic Escherichia coli reduces the inner mucus layer and promotes adherence to human colonic epithelium ex vivo
    Cell Microbiol (2017) 19, e12717-e12717. PubMed  Europe PubMed DOI  T
    7. 2012
  7. Szabady,R.L. and Welch,R.A.
    StcE peptidase and the StcE-like metalloendopeptidases
    [ISSN:978-0-12-407744-7] (2012) 3, 1272-1280. DOI
  8. Yu,A.C., Worrall,L.J. and Strynadka,N.C.
    Structural insight into the bacterial mucinase StcE essential to adhesion and immune evasion during enterohemorrhagic E. coli infection
    Structure (2012) 20, 707-717. PubMed  Europe PubMed DOI
    9. 2011
  9. Szabady,R.L., Yanta,J.H., Halladin,D.K., Schofield,M.J. and Welch,R.A.
    TagA is a secreted protease of Vibrio cholerae that specifically cleaves mucin glycoproteins
    Microbiology (Reading) (2011) 157, 516-525. PubMed  Europe PubMed DOI  P
    10. 2009
  10. Szabady,R.L., Lokuta,M.A., Walters,K.B., Huttenlocher,A. and Welch,R.A.
    Modulation of neutrophil function by a secreted mucinase of Escherichia coli O157:H7
    PLoS Pathog (2009) 5, e1000320-e1000320. PubMed  Europe PubMed DOI  PMC  EPMC
    11. 2006
  11. Grys,T.E., Walters,L.L. and Welch,R.A.
    Characterization of the StcE protease activity of Escherichia coli O157:H7
    J Bacteriol (2006) 188, 4646-4653. PubMed  Europe PubMed DOI  PMC  EPMC
  12. Pillai,L., Sha,J., Erova,T.E., Fadl,A.A., Khajanchi,B.K. and Chopra,A.K.
    Molecular and functional characterization of a ToxR-regulated lipoprotein from a clinical isolate of Aeromonas hydrophila
    Infect Immun (2006) 74, 3742-3755. PubMed  Europe PubMed DOI  PMC  EPMC  E
    13. 2005
  13. Grys,T.E., Siegel,M.B., Lathem,W.W. and Welch,R.A.
    The StcE protease contributes to intimate adherence of enterohemorrhagic Escherichia coli O157:H7 to host cells
    Infect Immun (2005) 73, 1295-1303. PubMed  Europe PubMed DOI  PMC  EPMC
  14. Withey,J.H. and DiRita,V.J.
    Vibrio cholerae ToxT independently activates the divergently transcribed aldA and tagA genes
    J Bacteriol (2005) 187, 7890-7900. PubMed  Europe PubMed DOI  PMC  EPMC
    15. 2004
  15. [YEAR:19-4-2004]Lathem,W.W., Bergsbaken,T. and Welch,R.A.
    Potentiation of C1 esterase inhibitor by StcE, a metalloprotease secreted by Escherichia coli O157:H7
    J Exp Med (19-4-2004) 199, 1077-1087. PubMed  Europe PubMed DOI  PMC  EPMC
  16. Ravindran,S., Grys,T.E., Welch,R.A., Schapira,M. and Patston,P.A.
    Inhibition of plasma kallikrein by C1-inhibitor: role of endothelial cells and the amino-terminal domain of C1-inhibitor
    Thromb Haemost (2004) 92, 1277-1283. PubMed  Europe PubMed DOI
    17. 2003
  17. [YEAR:15-6-2003]Lathem,W.W., Bergsbaken,T., Witowski,S.E., Perna,N.T. and Welch,R.A.
    Acquisition of stcE, a C1 esterase inhibitor-specific metalloprotease, during the evolution of Escherichia coli O157:H7
    J Infect Dis (15-6-2003) 187, 1907-1914. PubMed  Europe PubMed DOI
    18. 2002
  18. Lathem,W.W., Grys,T.E., Witowski,S.E., Torres,A.G., Kaper,J.B., Tarr,P.I. and Welch,R.A.
    StcE, a metalloprotease secreted by Escherichia coli O157:H7, specifically cleaves C1 esterase inhibitor
    Mol Microbiol (2002) 45, 277-288. PubMed  Europe PubMed DOI
  19. Paton,A.W. and Paton,J.C.
    Reactivity of convalescent-phase hemolytic-uremic syndrome patient sera with the megaplasmid-encoded TagA protein of Shiga toxigenic Escherichia coli O157
    J Clin Microbiol (2002) 40, 1395-1399. PubMed  Europe PubMed DOI  PMC  EPMC

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