Literature for peptidase M41.026: YME1L1 g.p. (Homo sapiens) and similar

(Topics flags: M Mutation, K Knockout. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Demetriadou,A., Grafakou,O., Georgiou,T., Burska,D., Malekkou,A., Krizova,J., Paramera,E., Mavrikiou,G., Dionysiou,M., Theodosiou,A., Sismani,C., Anastasiadou,V., Ioannou,I., Papakonstantinou,E., Hansikova,H., Drousiotou,A. and Petrou,P.P.
   YME1L1 Dysfunction Associated With 3-Methylglutaconic Aciduria
   J Inherit Metab Dis48, e70029-e70029. PubMed  Europe PubMed DOI
2. Eldeeb,M.A., Shahid,M. and Fon,E.A.
   Cell biology: Mitochondrial protease degrades unoccupied translocases upon import stress
   Curr Biol35, R287-R287. PubMed  Europe PubMed DOI
3. Hsu,M.C., Kinefuchi,H., Lei,L., Kikuchi,R., Yamano,K. and Youle,R.J.
   Mitochondrial YME1L1 governs unoccupied protein translocase channels
   Nat Cell Biol PubMed  Europe PubMed DOI
2024
4. Baker,M.J., Blau,K.U., Anderson,A.J., Palmer,C.S., Fielden,L.F., Crameri,J.J., Milenkovic,D., Thorburn,D.R., Frazier,A.E., Langer,T. and Stojanovski,D.
   CLPB disaggregase dysfunction impacts the functional integrity of the proteolytic SPY complex
   J Cell Biol223, PubMed  Europe PubMed DOI
5. Tan,S., Dengler,A.S., Darawsheh,R.Z. and Kory,N.
   The iAAA-mitochondrial protease YME1L1 regulates the degradation of the short-lived mitochondrial transporter SLC25A38
   bioRxiv PubMed  Europe PubMed DOI
6. Xin,W., Zhou,J., Peng,Y., Gong,S., Liao,W., Wang,Y., Huang,X., Mao,Y., Yao,M., Qin,S., Xiong,J., Li,Y., Lan,Q., Huang,Y. and Zhao,J.
   SREBP1c-Mediated Transcriptional Repression of YME1L1 Contributes to Acute Kidney Injury by Inducing Mitochondrial Dysfunction in Tubular Epithelial Cells
   Adv Sci (Weinh)e2412233-e2412233. PubMed  Europe PubMed DOI
2023
7. Qiu,J., Yue,F., Zhu,P., Chen,J., Xu,F., Zhang,L., Kim,K.H., Snyder,M.M., Luo,N., Xu,H.W., Huang,F., Tao,W.A. and Kuang,S.
   FAM210A is essential for cold-induced mitochondrial remodeling in brown adipocytes
   Nat Commun14, 6344-6344. PubMed  Europe PubMed DOI
8. Zhou,D., Sun,M.H., Jiang,W.J., Li,X.H., Lee,S.H., Heo,G., Choi,J., Kim,K.S. and Cui,X.S.
   Knock-down of YME1L1 induces mitochondrial dysfunction during early porcine embryonic development
   Front Cell Dev Biol11, 1147095-1147095. PubMed  Europe PubMed DOI  K
2022
9. Purandare,N., Kunji,Y., Xi,Y., Romero,R., Gomez-Lopez,N., Fribley,A., Grossman,L.I. and Aras,S.
   Lipopolysaccharide induces placental mitochondrial dysfunction in murine and human systems by reducing MNRR1 levels via a TLR4-independent pathway
   iScience25, 105342-105342. PubMed  Europe PubMed DOI
2021
10. Sprenger,H.G., MacVicar,T., Bahat,A., Fiedler,K.U., Hermans,S., Ehrentraut,D., Ried,K., Milenkovic,D., Bonekamp,N., Larsson,N.G., Nolte,H., Giavalisco,P. and Langer,T.
    Cellular pyrimidine imbalance triggers mitochondrial DNA-dependent innate immunity
    Nat Metab3, 636-650. PubMed  Europe PubMed DOI
2020
11. Lee,Y.J., Kim,G.H., Park,S.I. and Lim,J.H.
    Down-regulation of the mitochondrial i-AAA protease Yme1L induces muscle atrophy via FoxO3a and myostatin activation
    J Cell Mol Med24, 899-909. PubMed  Europe PubMed DOI  K
12. Li,S., Wu,Z., Tantray,I., Li,Y., Chen,S., Dong,J., Glynn,S., Vogel,H., Snyder,M. and Lu,B.
    Quality-control mechanisms targeting translationally stalled and C-terminally extended poly(GR) associated with ALS/FTD
    Proc Natl Acad Sci U S A117, 25104-25115. PubMed  Europe PubMed DOI
13. Miller,J.M., Brambley,C.A. and Marsee,J.D.
    Examination of the Role of Mg(2+) in the Mechanism of Nucleotide Binding to the Monomeric YME1L AAA+ Domain
    Biochemistry59, 4303-4320. PubMed  Europe PubMed DOI
14. Moore,S., Pickens,A., Rodriguez,J.L., Marsee,J.D. and Miller,J.M.
    Fluorescence methods applied to the description of urea-dependent YME1L protease unfolding
    Biomolecules10, 656-656. PubMed  Europe PubMed DOI
15. Ohba,Y., MacVicar,T. and Langer,T.
    Regulation of mitochondrial plasticity by the i-AAA protease YME1L
    Biol Chem401, 877-890. PubMed  Europe PubMed DOI
2019
16. Ando,K., Yokochi,T., Mukai,A., Wei,G., Li,Y., Kramer,S., Ozaki,T., Maehara,Y. and Nakagawara,A.
    Tumor suppressor KIF1Bbeta regulates mitochondrial apoptosis in collaboration with YME1L1
    Mol Carcinog58, 1134-1144. PubMed  Europe PubMed DOI
17. Brambley,C.A., Marsee,J.D., Halper,N. and Miller,J.M.
    Characterization of mitochondrial YME1L protease oxidative stress-induced conformational state
    J Mol Biol431, 1250-1266. PubMed  Europe PubMed DOI
18. MacVicar,T., Ohba,Y., Nolte,H., Mayer,F.C., Tatsuta,T., Sprenger,H.G., Lindner,B., Zhao,Y., Li,J., Bruns,C., Kruger,M., Habich,M., Riemer,J., Schwarzer,R., Pasparakis,M., Henschke,S., Bruning,J.C., Zamboni,N. and Langer,T.
    Lipid signalling drives proteolytic rewiring of mitochondria by YME1L
    Nature575, 361-365. PubMed  Europe PubMed DOI
19. Richter,F., Dennerlein,S., Nikolov,M., Jans,D.C., Naumenko,N., Aich,A., MacVicar,T., Linden,A., Jakobs,S., Urlaub,H., Langer,T. and Rehling,P.
    ROMO1 is a constituent of the human presequence translocase required for YME1L protease import
    J Cell Biol218, 598-614. PubMed  Europe PubMed DOI
2018
20. Cesnekova,J., Rodinova,M., Hansikova,H., Zeman,J. and Stiburek,L.
    Loss of mitochondrial AAA proteases AFG3L2 and YME1L impairs mitochondrial structure and respiratory chain biogenesis
    Int J Mol Sci19, 3930-3930. PubMed  Europe PubMed DOI  K
21. Sprenger,H.G., Wani,G., Hesseling,A., Konig,T., Patron,M., MacVicar,T., Ahola,S., Wai,T., Barth,E., Rugarli,E.I., Bergami,M. and Langer,T.
    Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy
    EMBO Mol Med11, e9288-e9288. PubMed  Europe PubMed DOI  M
2017
22. Srinivasainagendra,V., Sandel,M.W., Singh,B., Sundaresan,A., Mooga,V.P., Bajpai,P., Tiwari,H.K. and Singh,K.K.
    Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma
    Genome Med9, 31-31. PubMed  Europe PubMed DOI  M
2016
23. [YEAR:15-3-2016]Cesnekova,J., Rodinova,M., Hansikova,H., Houstek,J., Zeman,J. and Stiburek,L.
    The mammalian homologue of yeast Afg1 ATPase (lactation elevated 1) mediates degradation of nuclear-encoded complex IV subunits
    Biochem J473, 797-804. PubMed  Europe PubMed
24. Hartmann,B., Wai,T., Hu,H., MacVicar,T., Musante,L., Fischer-Zirnsak,B., Stenzel,W., Graf,R., van den Heuvel,L., Ropers,H.H., Wienker,T.F., Hubner,C., Langer,T. and Kaindl,A.M.
    Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation
    elife5, e16078-e16078. PubMed  Europe PubMed DOI  M
25. MacVicar,T. and Langer,T.
    OPA1 processing in cell death and disease - the long and short of it
    J Cell Sci129, 2297-2306. PubMed  Europe PubMed DOI
26. Rainbolt,T.K., Saunders,J.M. and Wiseman,R.L.
    YME1L degradation reduces mitochondrial proteolytic capacity during oxidative stress
    EMBO Rep16, 97-106. PubMed  Europe PubMed DOI
27. Shi,H., Rampello,A.J. and Glynn,S.E.
    Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane
    Nat Commun7, 13301-13301. PubMed  Europe PubMed DOI
2014
28. Anand,R., Wai,T., Baker,M.J., Kladt,N., Schauss,A.C., Rugarli,E. and Langer,T.
    The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission
    J Cell Biol204, 919-929. PubMed  Europe PubMed DOI
2013
29. Ruan,Y., Li,H., Zhang,K., Jian,F., Tang,J. and Song,Z.
    Loss of Yme1L perturbates mitochondrial dynamics
    Cell Death Dis4, e896-e896. PubMed  Europe PubMed DOI
2012
30. Stiburek,L., Cesnekova,J., Kostkova,O., Fornuskova,D., Vinsova,K., Wenchich,L., Houstek,J. and Zeman,J.
    YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation
    Mol Biol Cell23, 1010-1023. PubMed  Europe PubMed DOI
2009
31. Head,B., Griparic,L., Amiri,M., Gandre-Babbe,S. and van der Bliek,A.M.
    Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells
    J Cell Biol187, 959-966. PubMed  Europe PubMed DOI
2007
32. Song,Z., Chen,H., Fiket,M., Alexander,C. and Chan,D.C.
    OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L
    J Cell Biol178, 749-755. PubMed  Europe PubMed DOI
2005
33. Coenen,M.J., Smeitink,J.A., Smeets,R., Trijbels,F.J. and van den Heuvel,L.P.
    Mutation detection in four candidate genes (OXA1L, MRS2L, YME1L and MIPEP) for combined deficiencies in the oxidative phosphorylation system
    J Inherit Metab Dis28, 1091-1097. PubMed  Europe PubMed DOI  M
2000
34. [YEAR:15-5-2000]Coppola,M., Pizzigoni,A., Banfi,S., Bassi,M.T., Casari,G. and Incerti,B.
    Identification and characterization of YME1L1, a novel paraplegin-related gene
    Genomics66, 48-54. PubMed  Europe PubMed DOI
35. [YEAR:4-8-2000]Shah,Z.H., Hakkaart,G.A., Arku,B., de Jong,L., van der Spek,H., Grivell,L.A. and Jacobs,H.T.
    The human homologue of the yeast mitochondrial AAA metalloprotease Yme1p complements a yeast yme1 disruptant
    FEBS Lett478, 267-270. PubMed  Europe PubMed DOI