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Literature for peptidase M41.005: AtFtsH2 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature

(Topics flags: M Mutation, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Chai,X., Chen,J., Fu,C., Zhang,J., Zhao,X., Lyu,H.N., Xia,S., Li,X., Suo,Y., Shi,Q., Wang,J. and Xu,C.<br>Exploring leaf variegation in Arabidopsis yellow variegated2 by single-cell RNA sequencing<br>Plant J (2026) 125, e70659-e70659. PubMed  Europe PubMed DOI
    2. 2025
  2. Wang,P., Zhu,L., Wang,X., Zhai,Y., Zhong,J., Zhang,H., Shao,J., Liu,X., Yu,F. and Qi,Y.<br>Balance of chlorophyll synthesis and thylakoid protein quality control influences chloroplast development in var2<br>J Exp Bot (2025) PubMed  Europe PubMed DOI
  3. Wu,W., Guo,W., Zhu,H., Li,D., Zhang,Z., Lin,D., Qu,M., Yu,Z. and Huang,J.<br>Arabidopsis Leaf variegation is caused by simultaneous defects in chloroplast development and division<br>Plant Commun (2025) , 101564-101564. PubMed  Europe PubMed DOI
    4. 2024
  4. Liu,D., Luo,S., Li,Z., Liang,G., Guo,Y., Xu,Y. and Chong,K.<br>COG3 confers the chilling tolerance to mediate OsFtsH2-D1 module in rice<br>New Phytol (2024) 241, 2143-2157. PubMed  Europe PubMed DOI
    5. 2022
  5. Wang,X., Li,Q., Zhang,Y., Pan,M., Wang,R., Sun,Y., An,L., Liu,X., Yu,F. and Qi,Y.<br>VAR2/AtFtsH2 and EVR2/BCM1/CBD1 synergistically regulate the accumulation of PSII reaction centre D1 protein during de-etiolation in Arabidopsis<br>Plant Cell Environ (2022) 45, 2395-2409. PubMed  Europe PubMed DOI
    6. 2021
  6. Luo,S. and Kim,C.<br>Current Understanding of Temperature Stress-Responsive Chloroplast FtsH Metalloproteases<br>Int J Mol Sci (2021) 22, 12106-12106. PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2020
  7. Qi,Y., Wang,X., Lei,P., Li,H., Yan,L., Zhao,J., Meng,J., Shao,J., An,L., Yu,F. and Liu,X.<br>The chloroplast metalloproteases VAR2 and EGY1 act synergistically to regulate chloroplast development in Arabidopsis<br>J Biol Chem (2020) 295, 1036-1046. PubMed  Europe PubMed DOI
    8. 2019
  8. Kato,Y. and Sakamoto,W.<br>Phosphorylation of the chloroplastic metalloprotease FtsH in Arabidopsis characterized by Phos-Tag SDS-PAGE<br>Front Plant Sci (2019) 10, 1080-1080. PubMed  Europe PubMed DOI  PMC  EPMC
    9. 2018
  9. Kato,Y. and Sakamoto,W.<br>FtsH protease in the thylakoid membrane: physiological functions and the regulation of protease activity<br>Front Plant Sci (2018) 9, 855-855. PubMed  Europe PubMed DOI  PMC  EPMC  V
    10. 2017
  10. Dogra,V., Duan,J., Lee,K.P., Lv,S., Liu,R. and Kim,C.<br>FtsH2-Dependent proteolysis of EXECUTER1 is essential in mediating singlet oxygen-triggered retrograde signaling in Arabidopsis thaliana<br>Front Plant Sci (2017) 8, 1145-1145. PubMed  Europe PubMed DOI  PMC  EPMC
  11. Wang,F., Qi,Y., Malnoe,A., Choquet,Y., Wollman,F.A. and de Vitry,C.<br>The high light response and redox control of thylakoid FtsH protease in Chlamydomonas reinhardtii<br>Mol Plant (2017) 10, 99-114. PubMed  Europe PubMed DOI
    12. 2016
  12. Jarvi,S., Suorsa,M., Tadini,L., Ivanauskaite,A., Rantala,S., Allahverdiyeva,Y., Leister,D. and Aro,E.M.<br>Thylakoid-bound FtsH proteins facilitate proper biosynthesis of photosystem I<br>Plant Physiol (2016) 171, 1333-1343. PubMed  Europe PubMed DOI  M
  13. Wang,L., Kim,C., Xu,X., Piskurewicz,U., Dogra,V., Singh,S., Mahler,H. and Apel,K.<br>Singlet oxygen- and EXECUTER1-mediated signaling is initiated in grana margins and depends on the protease FtsH2<br>Proc Natl Acad Sci U S A (2016) 113, E3792-E3800. PubMed  Europe PubMed DOI
    14. 2015
  14. Sacharz,J., Bryan,S.J., Yu,J., Burroughs,N.J., Spence,E.M., Nixon,P.J. and Mullineaux,C.W.<br>Sub-cellular location of FtsH proteases in the cyanobacterium Synechocystis sp. PCC 6803 suggests localised PSII repair zones in the thylakoid membranes<br>Mol Microbiol (2015) 96, 448-462. PubMed  Europe PubMed DOI
    15. 2014
  15. Krynicka,V., Tichy,M., Krafl,J., Yu,J., Kana,R., Boehm,M., Nixon,P.J. and Komenda,J.<br>Two essential FtsH proteases control the level of the Fur repressor during iron deficiency in the cyanobacterium Synechocystis sp. PCC 6803<br>Mol Microbiol (2014) 94, 609-624. PubMed  Europe PubMed DOI
  16. Malnoe,A., Wang,F., Girard-Bascou,J., Wollman,F.A. and de Vitry,C.<br>Thylakoid FtsH protease contributes to photosystem II and cytochrome b6f remodeling in Chlamydomonas reinhardtii under stress conditions<br>Plant Cell (2014) 26, 373-390. PubMed  Europe PubMed DOI
  17. Yoshioka-Nishimura,M. and Yamamoto,Y.<br>Quality control of photosystem II: the molecular basis for the action of FtsH protease and the dynamics of the thylakoid membranes<br>J Photochem Photobiol B (2014) 137, 100-106. PubMed  Europe PubMed DOI
    18. 2013
  18. Kato,Y. and Sakamoto,W.<br>Possible compensatory role among chloroplast proteases under excess-light stress condition<br>Plant Signal Behav (2013) 8, e23198-e23198. PubMed  Europe PubMed DOI
  19. Lucinski,R. and Jackowski,G.<br>AtFtsH heterocomplex-mediated degradation of apoproteins of the major light harvesting complex of photosystem II (LHCII) in response to stresses<br>J Plant Physiol (2013) 170, 1082-1089. PubMed  Europe PubMed DOI
    20. 2012
  20. Adam,Z.<br>FtsH homolog in chloroplasts<br>[ISSN:978-0-12-407744-7] (2012) 3, 710-713. DOI
  21. Boehm,M., Yu,J., Krynicka,V., Barker,M., Tichy,M., Komenda,J., Nixon,P.J. and Nield,J.<br>Subunit organization of a Synechocystis hetero-oligomeric thylakoid FtsH complex involved in photosystem II repair<br>Plant Cell (2012) 24, 3669-3683. PubMed  Europe PubMed DOI
  22. Chi,W., Sun,X. and Zhang,L.<br>The roles of chloroplast proteases in the biogenesis and maintenance of photosystem II<br>Biochim Biophys Acta (2012) 1817, 239-246. PubMed  Europe PubMed DOI
  23. Kato,Y., Kouso,T. and Sakamoto,W.<br>Variegated tobacco leaves generated by chloroplast FtsH suppression: implication of FtsH function in the maintenance of thylakoid membranes<br>Plant Cell Physiol (2012) 53, 391-404. PubMed  Europe PubMed DOI  K
  24. Kato,Y., Sun,X., Zhang,L. and Sakamoto,W.<br>Cooperative D1 degradation in the photosystem II repair mediated by chloroplastic proteases in Arabidopsis<br>Plant Physiol (2012) 159, 1428-1439. PubMed  Europe PubMed DOI
  25. Moldavski,O., Levin-Kravets,O., Ziv,T., Adam,Z. and Prag,G.<br>The Hetero-Hexameric Nature of a Chloroplast AAA+ FtsH Protease Contributes to Its Thermodynamic Stability<br>PLoS ONE (2012) 7, e36008-e36008. PubMed  Europe PubMed DOI  PMC  EPMC
  26. Wagner,R., Aigner,H. and Funk,C.<br>FtsH proteases located in the plant chloroplast<br>Physiol Plant (2012) 145, 203-214. PubMed  Europe PubMed DOI
    27. 2011
  27. Adam,Z., Frottin,F., Espagne,C., Meinnel,T. and Giglione,C.<br>Interplay between N-terminal methionine excision and FtsH protease is essential for normal chloroplast development and function in Arabidopsis<br>Plant Cell (2011) 23, 3745-3760. PubMed  Europe PubMed DOI
  28. Baranek,M., Grabsztunowicz,M., Sikora,B. and Jackowski,G.<br>[ATP-dependent FtsH and Lon chloroplast proteases]<br>Postepy Biochem (2011) 57, 101-108. PubMed  Europe PubMed
  29. Rodrigues,R.A., Silva-Filho,M.C. and Cline,K.<br>FtsH2 and FtsH5: two homologous subunits use different integration mechanisms leading to the same thylakoid multimeric complex<br>Plant J (2011) 65, 600-609. PubMed  Europe PubMed DOI
  30. Wagner,R., Aigner,H., Pruzinska,A., Jankanpaa,H.J., Jansson,S. and Funk,C.<br>Fitness analyses of Arabidopsis thaliana mutants depleted of FtsH metalloproteases and characterization of three FtsH6 deletion mutants exposed to high light stress, senescence and chilling<br>New Phytol (2011) 191, 449-458. PubMed  Europe PubMed DOI
  31. Yoshioka,M. and Yamamoto,Y.<br>Quality control of photosystem II: where and how does the degradation of the D1 protein by FtsH proteases start under light stress? - Facts and hypotheses<br>J Photochem Photobiol B (2011) 104, 229-235. PubMed  Europe PubMed DOI
  32. Yu,F., Park,S.S., Liu,X., Foudree,A., Fu,A., Powikrowska,M., Khrouchtchova,A., Jensen,P.E., Kriger,J.N., Gray,G.R. and Rodermel,S.R.<br>SUPPRESSOR OF VARIEGATION4, a new var2 suppressor locus, encodes a pioneer protein that is required for chloroplast biogenesis<br>Mol Plant (2011) 4, 229-240. PubMed  Europe PubMed
    33. 2010
  33. Nixon,P.J., Michoux,F., Yu,J., Boehm,M. and Komenda,J.<br>Recent advances in understanding the assembly and repair of photosystem II<br>Ann Bot (2010) 106, 1-16. PubMed  Europe PubMed DOI
  34. Yue,G., Hu,X., He,Y., Yang,A. and Zhang,J.<br>Identification and characterization of two members of the FtsH gene family in maize (Zea mays L.)<br>Mol Biol Rep (2010) 37, 855-863. PubMed  Europe PubMed DOI
    35. 2009
  35. Zhang,J. and Sun,A.<br>Genome-wide comparative analysis of the metalloprotease FtsH gene families between Arabidopsis thaliana and rice<br>Sheng Wu Gong Cheng Xue Bao (2009) 25, 1402-1408. PubMed  Europe PubMed
    36. 2008
  36. Yu,F., Liu,X., Alsheikh,M., Park,S. and Rodermel,S.<br>Mutations in SUPPRESSOR OF VARIEGATION1, a factor required for normal chloroplast translation, suppress var2-mediated leaf variegation in Arabidopsis<br>Plant Cell (2008) 20, 1786-1804. PubMed  Europe PubMed DOI  PMC  EPMC
    37. 2007
  37. Komayama,K., Khatoon,M., Takenaka,D., Horie,J., Yamashita,A., Yoshioka,M., Nakayama,Y., Yoshida,M., Ohira,S., Morita,N., Velitchkova,M., Enami,I. and Yamamoto,Y.<br>Quality control of photosystem II: cleavage and aggregation of heat-damaged D1 protein in spinach thylakoids<br>Biochim Biophys Acta (2007) 1767, 838-846. PubMed  Europe PubMed DOI
    38. 2006
  38. [YEAR:5-4-2006]Adam,Z., Rudella,A. and van Wijk,K.J.<br>Recent advances in the study of Clp, FtsH and other proteases located in chloroplasts<br>Curr Opin Plant Biol (5-4-2006) 9, 234-240. PubMed  Europe PubMed DOI
  39. Aluru,M.R., Yu,F., Fu,A. and Rodermel,S.<br>Arabidopsis variegation mutants: new insights into chloroplast biogenesis<br>J Exp Bot (2006) 57, 1871-1881. PubMed  Europe PubMed DOI
    40. 2005
  40. Adam,Z., Zaltsman,A., Sinvany-Villalobo,G. and Sakamoto,W.<br>FtsH proteases in chloroplasts and cyanobacteria<br>Physiol Plant (2005) 123, 386-390.  V
  41. [YEAR:15-11-2005]Nixon,P.J., Barker,M., Boehm,M., de Vries,R. and Komenda,J.<br>FtsH-mediated repair of the photosystem II complex in response to light stress<br>J Exp Bot (15-11-2005) 56, 357-363. PubMed  Europe PubMed DOI
  42. Yu,F., Park,S. and Rodermel,S.R.<br>Functional redundancy of AtFtsH metalloproteases in thylakoid membrane complexes<br>Plant Physiol (2005) 138, 1957-1966. PubMed  Europe PubMed DOI  PMC  EPMC
  43. Zaltsman,A., Feder,A. and Adam,Z.<br>Developmental and light effects on the accumulation of FtsH protease in Arabidopsis chloroplasts - implications for thylakoid formation and photosystem II maintenance<br>Plant J (2005) 42, 609-617. PubMed  Europe PubMed DOI
  44. [YEAR:26-8-2005]Zaltsman,A., Ori,N. and Adam,Z.<br>Two types of FtsH protease subunits are required for chloroplast biogenesis and photosystem II repair in Arabidopsis<br>Plant Cell (26-8-2005) 17, 2782-2790. PubMed  Europe PubMed DOI  PMC  EPMC
    45. 2004
  45. Adam,Z.<br>Ftsh homologue in chloroplast<br>[ISSN:0-12-079610-4] (2004) 2, 805-807.  V
  46. Sakamoto,W., Miura,E., Kaji,Y., Okuno,T., Nishizono,M. and Ogura,T.<br>Allelic characterization of the leaf-variegated mutation var2 identifies the conserved amino acid residues of FtsH that are important for ATP hydrolysis and proteolysis<br>Plant Mol Biol (2004) 56, 705-716. PubMed  Europe PubMed DOI
  47. Sinvany-Villalobo,G., Davydov,O., Ben-Ari,G., Zaltsman,A., Raskind,A. and Adam,Z.<br>Expression in multigene families. Analysis of chloroplast and mitochondrial proteases<br>Plant Physiol (2004) 135, 1336-1345. PubMed  Europe PubMed DOI  PMC  EPMC
  48. Yu,F., Park,S. and Rodermel,S.R.<br>The Arabidopsis FtsH metalloprotease gene family: interchangeability of subunits in chloroplast oligomeric complexes<br>Plant J (2004) 37, 864-876. PubMed  Europe PubMed DOI
    49. 2003
  49. Sakamoto,W., Zaltsman,A., Adam,Z. and Takahashi,Y.<br>Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes<br>Plant Cell (2003) 15, 2843-2855. PubMed  Europe PubMed DOI  PMC  EPMC
    50. 2002
  50. [YEAR:18-1-2002]Bailey,S., Thompson,E., Nixon,P.J., Horton,P., Mullineaux,C.W., Robinson,C. and Mann,N.H.<br>A critical role for the Var2 FtsH homologue of Arabidopsis thaliana in the photosystem II repair cycle in vivo<br>J Biol Chem (18-1-2002) 277, 2006-2011. PubMed  Europe PubMed DOI
    51. 2001
  51. Adam,Z., Adamska,I., Nakabayashi,K., Ostersetzer,O., Haussuhl,K., Manuell,A., Zheng,B., Vallon,O., Rodermel,S.R., Shinozaki,K. and Clarke,A.K.<br>Chloroplast and mitochondrial proteases in Arabidopsis. A proposed nomenclature<br>Plant Physiol (2001) 125, 1912-1918. PubMed  Europe PubMed DOI  PMC  EPMC
    52. 2000
  52. Chen,M., Choi,Y., Voytas,D.F. and Rodermel,S.<br>Mutations in the Arabidopsis VAR2 locus cause leaf variegation due to the loss of a chloroplast FtsH protease<br>Plant J (2000) 22, 303-313. PubMed  Europe PubMed DOI
  53. Takechi,K., Sodmergen, Murata,M., Motoyoshi,F. and Sakamoto,W.<br>The YELLOW VARIEGATED (VAR2) locus encodes a homologue of FtsH, an ATP-dependent protease in Arabidopsis<br>Plant Cell Physiol (2000) 41, 1334-1346. PubMed  Europe PubMed
    54. 1999
  54. Itoh,R., Takano,H., Ohta,N., Miyagishima,S., Kuroiwa,H. and Kuroiwa,T.<br>Two ftsH-family genes encoded in the nuclear and chloroplast genomes of the primitive red alga Cyanidioschyzon merolae<br>Plant Mol Biol (1999) 41, 321-337. PubMed  Europe PubMed DOI

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