Literature for peptidase M19.001: membrane dipeptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: A Assay, S Structure, R Splicing, K Knockout, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2021
  1. Guan,Y., Liang,X., Ma,Z., Hu,H., Liu,H., Miao,Z., Linkermann,A., Hellwege,J.N., Voight,B.F. and Susztak,K.
    A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis
    Nat Commun12, 5078-5078. PubMed  Europe PubMed DOI
  2. 2015
  3. Moulton,R.D., Ruterbories,K.J., Bedwell,D.W. and Mohutsky,M.A.
    In vitro characterization of the bioconversion of pomaglumetad methionil, a novel metabotropic glutamate 2/3 receptor agonist peptide prodrug
    Drug Metab Dispos43, 756-761. PubMed  Europe PubMed DOI  I
  4. 2012
  5. Hooper,N.M.
    Membrane dipeptidase
    [ISSN:978-0-12-407743-0]3, 1670-1673. DOI
  6. 2004
  7. [YEAR:5-7-2004]Gurulingappa,H., Buckhalts,P., Kinzler,K.W., Vogelstein,B. and Khan,S.R.
    Synthesis and evaluation of aminophosphinic acid derivatives as inhibitors of renal dipeptidase
    Bioorg Med Chem Lett14, 3531-3533. PubMed  Europe PubMed DOI  I
  8. Hooper,N.M.
    Membrane dipeptidase
    [ISSN:0-12-079610-4]2, 994-997.  V
  9. [YEAR:8-6-2004]McIver,C.M., Lloyd,J.M., Hewett,P.J. and Hardingham,J.E.
    Dipeptidase 1: a candidate tumor-specific molecular marker in colorectal carcinoma
    Cancer Lett209, 67-74. PubMed  Europe PubMed DOI
  10. 2003
  11. Ikeda,H., Ueda,M., Kobayashi,H. and Honda,Y.
    Localization and activity of membrane dipeptidase in bovine ciliary epithelium
    Invest Ophthalmol Vis Sci44, 37-43. PubMed  Europe PubMed DOI
  12. 2002
  13. [YEAR:9-8-2002]Nitanai,Y., Satow,Y., Adachi,H. and Tsujimoto,M.
    Crystal structure of human renal dipeptidase involved in beta-lactam hydrolysis
    J Mol Biol321, 177-184. PubMed  Europe PubMed DOI  S  I
  14. 2001
  15. [YEAR:15-8-2001]Parkin,E.T., Turner,A.J. and Hooper,N.M.
    Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase
    Biochem J358, 209-216. PubMed  Europe PubMed DOI
  16. 2000
  17. Choi,K., Park,S.W., Lee,K.J., Lee,H.B., Han,H.J., Park,S.K. and Park,H.S.
    Grass carp (Ctenopharyngodon idellus) bile may inhibit the release of renal dipeptidase from the proximal tubules by nitric oxide generation
    Kidney Blood Press Res23, 113-118. PubMed  Europe PubMed
  18. 1999
  19. Grondin,G., Hooper,N.M. and LeBel,D.
    Specific localization of membrane dipeptidase and dipeptidyl peptidase IV in secretion granules of two different pancreatic islet cells
    J Histochem Cytochem47, 489-498. PubMed  Europe PubMed
  20. Kera,Y., Liu,Z., Matsumoto,T., Sorimachi,Y., Nagasaki,H. and Yamada,R.H.
    Rat and human membrane dipeptidase: tissue distribution and developmental changes
    Comp Biochem Physiol B Biochem Mol Biol123, 53-58. PubMed  Europe PubMed DOI  I
  21. [YEAR:23-4-1999]Rajotte,D. and Ruoslahti,E.
    Membrane dipeptidase is the receptor for a lung-targeting peptide identified by in vivo phage display
    J Biol Chem274, 11593-11598. PubMed  Europe PubMed DOI
  22. [YEAR:15-3-1999]White,I.J., Lawson,J., Williams,C.H. and Hooper,N.M.
    A continuous fluorometric assay for leukotriene D4 hydrolase
    Anal Biochem268, 245-251. PubMed  Europe PubMed DOI  A  I
  23. 1998
  24. [YEAR:28-4-1998]Habib,G.M., Shi,Z.Z., Cuevas,A.A., Guo,Q., Matzuk,M.M. and Lieberman,M.W.
    Leukotriene D4 and cystinyl-bis-glycine metabolism in membrane-bound dipeptidase-deficient mice
    Proc Natl Acad Sci U S A95, 4859-4863. PubMed  Europe PubMed DOI  K
  25. Hofken,T., Linder,D., Kleene,R., Goke,B. and Wagner,A.C.
    Membrane dipeptidase and glutathione are major components of pig pancreatic zymogen granules
    Exp Cell Res244, 481-490. PubMed  Europe PubMed DOI
  26. 1997
  27. Hooper,N.M., Cook,S., Laine,J. and LeBel,D.
    Identification of membrane dipeptidase as a major glycosyl-phosphatidylinositol-anchored protein of the pancreatic zymogen granule membrane, and evidence for its release by phospholipase A
    Biochem J324, 151-157. PubMed  Europe PubMed  I
  28. Keynan,S., Hooper,N.M. and Turner,A.J.
    Identification by site-directed mutagenesis of three essential histidine residues in membrane dipeptidase, a novel mammalian zinc peptidase
    Biochem J326, 47-51. PubMed  Europe PubMed  I
  29. Keynan,S., Asipu,A., Hooper,N.M., Turner,A.J. and Blair,G.E.
    Stable and temperature-sensitive transformation of baby rat kidney cells by SV40 suppresses expression of membrane dipeptidase
    Oncogene15, 1241-1245. PubMed  Europe PubMed DOI
  30. We,J.S., Kang,B.Y., Lee,J.C., Lee,H.B. and Park,H.S.
    Identification of urinary dipeptidase as the released form of renal dipeptidase
    Kidney Blood Press Res20, 411-415. PubMed  Europe PubMed
  31. 1996
  32. [YEAR:5-7-1996]Habib,G.M., Barrios,R., Shi,Z.Z. and Lieberman,M.W.
    Four distinct membrane-bound dipeptidase RNAs are differentially expressed and show discordant regulation with gamma-glutamyl transpeptidase
    J Biol Chem271, 16273-16280. PubMed  Europe PubMed DOI  K  R
  33. Keynan,S., Habgood,N.T., Hooper,N.M. and Turner,A.J.
    Site-directed mutagenesis of conserved cysteine residues in porcine membrane dipeptidase. Cys 361 alone is involved in disulfide-linked dimerization
    Biochemistry35, 12511-12517. PubMed  Europe PubMed DOI
  34. Watanabe,T., Kera,Y., Matsumoto,T. and Yamada,R.H.
    Purification and kinetic properties of a D-amino-acid peptide hydrolyzing enzyme from pig kidney cortex and its tentative identification with renal membrane dipeptidase
    Biochim Biophys Acta1298, 109-118. PubMed  Europe PubMed DOI  I
  35. 1995
  36. Brewis,I.A., Ferguson,M.A., Mehlert,A., Turner,A.J. and Hooper,N.M.
    Structures of the glycosyl-phosphatidylinositol anchors of porcine and human renal membrane dipeptidase. Comprehensive structural studies on the porcine anchor and interspecies comparison of the glycan core structures
    J Biol Chem270, 22946-22956. PubMed  Europe PubMed DOI
  37. Heywood,S.P. and Hooper,N.M.
    Development and application of a fluorometric assay for mammalian membrane dipeptidase
    Anal Biochem226, 10-14. PubMed  Europe PubMed DOI  A
  38. 1994
  39. An,S., Schmidt,F.J. and Campbell,B.J.
    Molecular cloning of sheep lung dipeptidase: a glycosyl phosphatidylinositol-anchored ectoenzyme that converts leukotriene D4 to leukotriene E4
    Biochim Biophys Acta1226, 337-340. PubMed  Europe PubMed DOI
  40. Keynan,S., Hooper,N.M. and Turner,A.J.
    Directed mutagenesis of pig renal membrane dipeptidase. His219 is critical but the DHXXH motif is not essential for zinc binding or catalytic activity
    FEBS Lett349, 50-54. PubMed  Europe PubMed DOI
  41. 1993
  42. [YEAR:21-4-1993]Adachi,H., Katayama,T., Nakazato,H. and Tsujimoto,M.
    Importance of Glu-125 in the catalytic activity of human renal dipeptidase
    Biochim Biophys Acta1163, 42-48. PubMed  Europe PubMed DOI
  43. Austruy,E., Jeanpierre,C., Antignac,C., Whitmore,S.A., Van Cong,N., Bernheim,A., Callen,D.F. and Junien,C.
    Physical and genetic mapping of the dipeptidase gene DPEP1 to 16q24.3
    Genomics15, 684-687. PubMed  Europe PubMed DOI
  44. Brewis,I.A., Ferguson,M.A., Turner,A.J. and Hooper,N.M.
    Structural determination of the glycolipid anchors of human and porcine membrane dipeptidases
    Biochem Soc Trans21, 46S-46S. PubMed  Europe PubMed
  45. Brewis,I.A., Hooper,N.M. and Turner,A.J.
    Identification of the site of attachment of the glycolipid anchor in porcine membrane dipeptidase
    Biochem Soc Trans21, 44S-44S. PubMed  Europe PubMed
  46. Satoh,S., Keida,Y., Konta,Y., Maeda,M., Matsumoto,Y., Niwa,M. and Kohsaka,M.
    Purification and molecular cloning of mouse renal dipeptidase
    Biochim Biophys Acta1163, 234-242. PubMed  Europe PubMed DOI
  47. 1992
  48. [YEAR:20-10-1992]Adachi,H., Ishida,N. and Tsujimoto,M.
    Primary structure of rat renal dipeptidase and expression of its mRNA in rat tissues and COS-1 cells
    Biochim Biophys Acta1132, 311-314. PubMed  Europe PubMed DOI
  49. Nakagawa,H., Inazawa,J., Inoue,K., Misawa,S., Kashima,K., Adachi,H., Nakazato,H. and Abe,T.
    Assignment of the human renal dipeptidase gene (DPEP1) to band q24 of chromosome 16
    Cytogenet Cell Genet59, 258-260. PubMed  Europe PubMed
  50. 1991
  51. Igarashi,P. and Karniski,L.P.
    Cloning of cDNAs encoding a rabbit renal brush border membrane protein immunologically related to band 3. Sequence similarity with microsomal dipeptidase
    Biochem J280, 71-78. PubMed  Europe PubMed
  52. 1990
  53. Adachi,H., Tawaragi,Y., Inuzuka,C., Kubota,I., Tsujimoto,M., Nishihara,T. and Nakazato,H.
    Primary structure of human microsomal dipeptidase deduced from molecular cloning
    J Biol Chem265, 3992-3995. PubMed  Europe PubMed
  54. [YEAR:16-1-1990]Campbell,B.J., Baker,S.F., Shukla,S.D., Forrester,L.J. and Zahler,W.L.
    Bioconversion of leukotriene D4 by lung dipeptidase
    Biochim Biophys Acta1042, 107-112. PubMed  Europe PubMed DOI
  55. Hooper,N.M., Keen,J.N. and Turner,A.J.
    Characterization of the glycosyl-phosphatidylinositol-anchored human renal dipeptidase reveals that it is more extensively glycosylated than the pig enzyme
    Biochem J265, 429-433. PubMed  Europe PubMed
  56. Rached,E., Hooper,N.M., James,P., Semenza,G., Turner,A.J. and Mantei,N.
    cDNA cloning and expression in Xenopus laevis oocytes of pig renal dipeptidase, a glycosyl-phosphatidylinositol-anchored ectoenzyme
    Biochem J271, 755-760. PubMed  Europe PubMed
  57. 1989
  58. Adachi,H., Kubota,I., Okamura,N., Iwata,H., Tsujimoto,M., Nakazato,H., Nishihara,T. and Noguchi,T.
    Purification and characterization of human microsomal dipeptidase
    J Biochem105, 957-961. PubMed  Europe PubMed
  59. 1985
  60. Basker,M.J., Coulton,S. and Southgate,R.
    Mutual pro-drugs of the olivanic acids and renal dipeptidase inhibitors
    J Antibiot (Tokyo)38, 70-74. PubMed  Europe PubMed  I
  61. 1984
  62. [YEAR:10-12-1984]Campbell,B.J., Forrester,L.J., Zahler,W.L. and Burks,M.
    Beta-lactamase activity of purified and partially characterized human renal dipeptidase
    J Biol Chem259, 14586-14590. PubMed  Europe PubMed  I
  63. 1983
  64. Kahan,F.M., Kropp,H., Sundelof,J.G. and Birnbaum,J.
    Thienamycin: development of imipenen-cilastatin
    J Antimicrob Chemother12 Suppl D, 1-35. PubMed  Europe PubMed  I
  65. 1982
  66. [YEAR:29-10-1982]Kim,H.S. and Campbell,B.J.
    beta-Lactamase activity of renal dipeptidase against N-formimidoyl-thienamycin
    Biochem Biophys Res Commun108, 1638-1642. PubMed  Europe PubMed
  67. [YEAR:10-6-1982]Kozak,E.M. and Tate,S.S.
    Glutathione-degrading enzymes of microvillus membranes
    J Biol Chem257, 6322-6327. PubMed  Europe PubMed
  68. Kropp,H., Sundelof,J.G., Hajdu,R. and Kahan,F.M.
    Metabolism of thienamycin and related carbapenem antibiotics by the renal dipeptidase, dehydropeptidase
    Antimicrobial Agents Chemother22, 62-70. PubMed  Europe PubMed
  69. [YEAR:25-10-1982]McIntyre,T. and Curthoys,N.P.
    Renal catabolism of glutathione. Characterization of a particulate rat renal dipeptidase that catalyzes the hydrolysis of cysteinylglycine
    J Biol Chem257, 11915-11921. PubMed  Europe PubMed
  70. 1974
  71. [YEAR:9-4-1974]Armstrong,D.J., Mukhopadhyay,S.K. and Campbell,B.J.
    Physicochemical characterization of renal dipeptidase
    Biochemistry13, 1745-1750. PubMed  Europe PubMed
  72. 1971
  73. [YEAR:20-8-1971]Harper,C., Rene,A. and Campbell,B.J.
    Renal dipeptidase: localization and inhibition
    Biochim Biophys Acta242, 446-458. PubMed  Europe PubMed
  74. 1970
  75. Campbell,B.J.
    Renal dipeptidase
    Methods Enzymol19, 722-729. DOI  V
  76. 1969
  77. [YEAR:25-3-1969]Rene,A.M. and Campbell,B.J.
    Amino acid composition and effect of pH on the kinetic parameters of renal dipeptidase
    J Biol Chem244, 1445-1450. PubMed  Europe PubMed
  78. 1966
  79. Campbell,B.J., Lin,Y.C., Davis,R.V. and Ballew,E.
    The purification and properties of a particulate renal dipeptidase
    Biochim Biophys Acta118, 371-386. PubMed  Europe PubMed
  80. 1963
  81. Campbell,B.J., Lin,Y.C. and Bird,M.E.
    Renal aminopeptidase- and copper-activated peptide hydrolysis
    J Biol Chem238, 3632-3639. PubMed  Europe PubMed
  82. 1949
  83. Price,V.E. and Meister,A.
    The separation of dehydropeptidase and analogous L- and D-peptidases
    J Biol Chem181, 535-547. PubMed  Europe PubMed
  84. 1948
  85. Greenstein,J.P.
    Dehydropeptidases
    Adv Enzymol Relat Subj Biochem8, 117-169.
  86. Greenstein,J.P., Price,V.E. and Leuthardt,F.M.
    Studies on the possible multiple nature of dehydropeptidase I
    J Biol Chem175, 953-962. PubMed  Europe PubMed
  87. Rice,V.E. and Greenstein,J.P.
    Enzymatic hydrolysis of analogous saturated and unsaturated peptides
    J Biol Chem175, 969-974.
  88. 1947
  89. Yudkin,W.H. and Fruton,J.S.
    On the proteolytic enzymes of animal tissues. VI. Dehydropeptidase
    J Biol Chem169, 521-529. PubMed  Europe PubMed
  90. Yudkin,W.H. and Fruton,J.S.
    The activation of dehydropeptidase by zinc
    J Biol Chem170, 421-422.
  91. 1932
  92. Bergmann,M. and Schleich,H.
    [On the enzymatic cleavage of dehydropeptides. Discovery of a dehydropeptidase]
    Hoppe Seylers Z Physiol Chem205, 65-82.
  93. Bergmann,M.
    [Dehydrodipeptidase. Enzymic cleavage of compounds of pyruvic acid and amino acids]
    Hoppe Seylers Z Physiol Chem207, 235-240.