Merops Switch to
Inhibitors

Peptidase

Family Clan SEARCHES BLAST
MEROPS SUBMISSIONS

Other
information

Literature for peptidase M18.001: aminopeptidase I

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, I Inhibitor, P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2016
  1. Yamasaki,A., Watanabe,Y., Adachi,W., Suzuki,K., Matoba,K., Kirisako,H., Kumeta,H., Nakatogawa,H., Ohsumi,Y., Inagaki,F. and Noda,N.N.
    Structural basis for receptor-mediated selective autophagy of aminopeptidase I aggregates
    Cell Rep (2016) 16, 19-27. PubMed  Europe PubMed DOI
    2. 2015
  2. Su,M.Y., Peng,W.H., Ho,M.R., Su,S.C., Chang,Y.C., Chen,G.C. and Chang,C.I.
    Structure of yeast Ape1 and its role in autophagic vesicle formation
    Autophagy (2015) 11, 1580-1593. PubMed  Europe PubMed DOI  PMC  EPMC  S
    3. 2014
  3. Hecht,K.A., O'Donnell,A.F. and Brodsky,J.L.
    The proteolytic landscape of the yeast vacuole
    Cell Logist (2014) 4, e28023-e28023. PubMed  Europe PubMed DOI  PMC  EPMC  P
    4. 2012
  4. Morales Quinones,M., Winston,J.T. and Stromhaug,P.E.
    Propeptide of aminopeptidase 1 protein mediates aggregation and vesicle formation in cytoplasm-to-vacuole targeting pathway
    J Biol Chem (2012) 287, 10121-10133. PubMed  Europe PubMed DOI
  5. Suarez-Rendueles,P., Bordallo,J. and Cueva,R.
    Aminopeptidase I
    [ISSN:978-0-12-407743-0] (2012) 3, 1574-1576. DOI
    6. 2011
  6. Yuga,M., Gomi,K., Klionsky,D.J. and Shintani,T.
    Aspartyl aminopeptidase is imported from the cytoplasm to the vacuole by selective autophagy in Saccharomyces cerevisiae
    J Biol Chem (2011) 286, 13704-13713. PubMed  Europe PubMed DOI
    7. 2009
  7. Adamis,P.D., Mannarino,S.C., Riger,C.J., Duarte,G., Cruz,A., Pereira,M.D. and Eleutherio,E.C.
    Lap4, a vacuolar aminopeptidase I, is involved in cadmium-glutathione metabolism
    Biometals (2009) 22, 243-249. PubMed  Europe PubMed DOI
    8. 2008
  8. Schu,P.
    Aminopeptidase I enzymatic activity
    Methods Enzymol (2008) 451, 67-78. PubMed  Europe PubMed DOI  V
    9. 2004
  9. Suarez-Rendueles,P., Bordallo,J. and Cueva,R.
    Aminopeptidase I
    [ISSN:0-12-079610-4] (2004) 2, 940-941.  V
    10. 2002
  10. [YEAR:13-2-2002]Barth,H., Meiling-Wesse,K., Epple,U.D. and Thumm,M.
    Mai1p is essential for maturation of proaminopeptidase I but not for autophagy
    FEBS Lett (13-2-2002) 512, 173-179. PubMed  Europe PubMed DOI
    11. 2001
  11. [YEAR:13-4-2001]Andrei-Selmer,C., Knuppel,A., Satyanarayana,C., Heese,C. and Schu,P.V.
    A new class of mutants deficient in dodecamerization of aminopeptidase 1 and vacuolar transport
    J Biol Chem (13-4-2001) 276, 11606-11614. PubMed  Europe PubMed DOI
  12. [YEAR:3-8-2001]Leber,R., Silles,E., Sandoval,I.V. and Mazon,M.J.
    Yol082p, a novel CVT protein involved in the selective targeting of aminopeptidase I to the yeast vacuole
    J Biol Chem (3-8-2001) 276, 29210-29217. PubMed  Europe PubMed DOI
    13. 2000
  13. [YEAR:31-3-2000]Satyanarayana,C., Schroder-Kohne,S., Craig,E.A., Schu,P.V. and Horst,M.
    Cytosolic Hsp70s are involved in the transport of aminopeptidase 1 from the cytoplasm into the vacuole
    FEBS Lett (31-3-2000) 470, 232-238. PubMed  Europe PubMed DOI
  14. [YEAR:3-11-2000]Silles,E., Mazon,M.J., Gevaert,K., Goethals,M., Vandekerckhove,J., Leber,R. and Sandoval,I.V.
    Targeting of aminopeptidase I to the yeast vacuole is mediated by Ssa1p, a cytosolic member of the 70-kDa stress protein family
    J Biol Chem (3-11-2000) 275, 34054-34059. PubMed  Europe PubMed DOI
    15. 1999
  15. Martinez,E., Segui-Real,B., Silles,E., Mazon,M.J. and Sandoval,I.V.
    The prepropeptide of vacuolar aminopeptidase I is necessary and sufficient to target the fluorescent reporter protein GFP to the vacuole of yeast by the Ccvt pathway
    Mol Microbiol (1999) 33, 52-62. PubMed  Europe PubMed DOI
    16. 1997
  16. Scott,S.V., Baba,M., Ohsumi,Y. and Klionsky,D.J.
    Aminopeptidase I is targeted to the vacuole by a nonclassical vesicular mechanism
    J Cell Biol (1997) 138, 37-44. PubMed  Europe PubMed DOI  PMC  EPMC
    17. 1996
  17. Oda,M.N., Scott,S.V., Hefner-Gravink,A., Caffarelli,A.D. and Klionsky,D.J.
    Identification of a cytoplasm to vacuole targeting determinant in aminopeptidase I
    J Cell Biol (1996) 132, 999-1010. PubMed  Europe PubMed DOI  PMC  EPMC
  18. Van den Hazel,H.B., Kielland-Brandt,M.C. and Winther,J.R.
    Review: biosynthesis and function of yeast vacuolar proteases
    Yeast (1996) 12, 1-16. PubMed  Europe PubMed DOI  V
    19. 1995
  19. Bordallo,J. and Suarez-Rendueles,P.
    Identification of regulatory proteins that might be involved in carbon catabolite repression of the aminopeptidase I gene of the yeast Saccharomyces cerevisiae
    FEBS Lett (1995) 376, 120-124. PubMed  Europe PubMed DOI
  20. Bordallo,J., Cueva,R. and Suarez-Rendueles,P.
    Transcriptional regulation of the yeast vacuolar aminopeptidase yscI encoding gene (APE1) by carbon sources
    FEBS Lett (1995) 364, 13-16. PubMed  Europe PubMed DOI
  21. Segui-Real,B., Martinez,M. and Sandoval,I.V.
    Yeast aminopeptidase I is post-translationally sorted from the cytosol to the vacuole by a mechanism mediated by its bipartite N-terminal extension
    EMBO J (1995) 14, 5476-5484. PubMed  Europe PubMed  PMC  EPMC
    22. 1992
  22. Klionsky,D.J., Cueva,R. and Yaver,D.S.
    Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway
    J Cell Biol (1992) 119, 287-299. PubMed  Europe PubMed DOI  PMC  EPMC
    23. 1989
  23. Chang,Y.H. and Smith,J.A.
    Molecular cloning and sequencing of genomic DNA encoding aminopeptidase I from Saccharomyces cerevisiae
    J Biol Chem (1989) 264, 6979-6983. PubMed  Europe PubMed
  24. Cueva,R., Garcia-Alvarez,N. and Suarez-Rendueles,P.
    Yeast vacuolar aminopeptidase yscI. Isolation and regulation of the APE1 (LAP4) structural gene
    FEBS Lett (1989) 259, 125-129. PubMed  Europe PubMed DOI
    25. 1984
  25. Rohm,K.H.
    Interaction of the (2S,3S)-isomer of bestatin with yeast aminopeptidase I. Kinetic and binding studies
    Hoppe Seylers Z Physiol Chem (1984) 365, 1235-1246. PubMed  Europe PubMed  I
    26. 1981
  26. Hemmings,B.A., Zubenko,G.S., Hasilik,A. and Jones,E.W.
    Mutant defective in processing of an enzyme located in the lysosome-like vacuole of Saccharomyces cerevisiae
    Proc Natl Acad Sci U S A (1981) 78, 435-439. PubMed  Europe PubMed  PMC  EPMC
    27. 1978
  27. [YEAR:10-11-1978]Frey,J. and Rohm,K.H.
    Subcellular localization and levels of aminopeptidases and dipeptidase in Saccharomyces cerevisiae
    Biochim Biophys Acta (10-11-1978) 527, 31-41. PubMed  Europe PubMed
    28. 1977
  28. Marx,R., Metz,G. and Rohn,K.H.
    The quaternary structure of yeast aminopeptidase I. 2. Geometric arrangement of subunits
    Z Naturforsch [C] (1977) 32, 938-943. PubMed  Europe PubMed
  29. Metz,G., Marx,R. and Rohm,K.H.
    The quaternary structure of yeast aminopeptidase I. 1. Molecular forms and subunit size
    Z Naturforsch [C] (1977) 32, 929-937. PubMed  Europe PubMed
    30. 1976
  30. [YEAR:13-5-1976]Metz,G. and Rohm,K.H.
    Yeast aminopeptidase I. Chemical composition and catalytic properties
    Biochim Biophys Acta (13-5-1976) 429, 933-949. PubMed  Europe PubMed
    31. 1974
  31. Metz,G., Rohm,K.H. and Schneider,F.
    Proceedings: An aminopeptidase from yeast: substrate specificity and some molecular properties
    Hoppe Seylers Z Physiol Chem (1974) 355, 1230-1231. PubMed  Europe PubMed
    32. 1971
  32. Matile,P., Wiemken,A. and Guyer,W.
    A lysosomal aminopeptidase isozyme in differentiating yeast cells and protoplasts
    Planta (1971) 96, 43-53. PubMed  Europe PubMed DOI
    33. 1941
  33. Johnson,M.J.
    Isolation and properties of a pure yeast polypeptidase
    J Biol Chem (1941) 137, 575-586.

feedback
Page created 8-September-2023

EMBL-EBI logo

© 2026 EBI
Terms of use