Literature for peptidase M17.014: LAPTc aminopeptidase

(Topics flags: S Structure, I Inhibitor, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

2024
1. Aguado,M.E., Carvalho,S., Valdes-Tresanco,M.E., Lin,D., Padilla-Mejia,N., Corpas-Lopez,V., Tesarova,M., Lukes,J., Gray,D., Gonzalez-Bacerio,J., Wyllie,S. and Field,M.C.
   Identification and Validation of Compounds Targeting Leishmania major Leucyl-Aminopeptidase M17
   ACS Infect Dis10, 2002-2017. PubMed  Europe PubMed DOI  I
2. Izquierdo,M., Lin,D., O'Neill,S., Webster,L.A., Paterson,C., Thomas,J., Aguado,M.E., Colina Araujo,E., Alpizar-Pedraza,D., Joji,H., MacLean,L., Hope,A., Gray,D.W., Zoltner,M., Field,M.C., Gonzalez-Bacerio,J. and De Rycker,M.
   Identification of a potent and selective LAPTc inhibitor by RapidFire-Mass Spectrometry, with antichagasic activity
   PLoS Negl Trop Dis18, e0011956-e0011956. PubMed  Europe PubMed DOI  I
2021
3. Aguado,M.E., Gonzalez-Matos,M., Izquierdo,M., Quintana,J., Field,M.C. and Gonzalez-Bacerio,J.
   Expression in Escherichia coli, purification and kinetic characterization of LAPLm, a Leishmania major M17-aminopeptidase
   Protein Expr Purif183, 105877-105877. PubMed  Europe PubMed DOI
4. Bhat,S.Y. and Qureshi,I.A.
   Structural and Functional Basis of Potent Inhibition of Leishmanial Leucine Aminopeptidase by Peptidomimetics
   ACS Omega6, 19076-19085. PubMed  Europe PubMed DOI  I
2020
5. Izquierdo,M., Lin, O'Neill,S., Zoltner,M., Webster,L., Hope,A., Gray,D.W., Field,M.C. and Gonzalez-Bacerio,J.
   Development of a high-throughput screening assay to identify inhibitors of the major M17-leucyl aminopeptidase from Trypanosoma cruzi using RapidFire mass spectrometry
   SLAS Discov2472555220923367-2472555220923367. PubMed  Europe PubMed DOI  I
2019
6. Izquierdo,M., Aguado,M.E., Zoltner,M. and Gonzalez-Bacerio,J.
   High-level expression in Escherichia coli, purification and kinetic characterization of LAPTc, a Trypanosoma cruzi M17-aminopeptidase
   Protein J38, 167-180. PubMed  Europe PubMed DOI  E
2017
7. Timm,J., Valente,M., Garcia-Caballero,D., Wilson,K.S. and Gonzalez-Pacanowska,D.
   Structural characterization of acidic M17 leucine aminopeptidases from the TriTryps and evaluation of their role in nutrient starvation in Trypanosoma brucei
   mSphere2, PubMed  Europe PubMed DOI  S  I
2011
8. Cadavid-Restrepo,G., Gastardelo,T.S., Faudry,E., de Almeida,H., Bastos,I.M., Negreiros,R.S., Lima,M.M., Assumpcao,T.C., Almeida,K.C., Ragno,M., Ebel,C., Ribeiro,B.M., Felix,C.R. and Santana,J.M.
   The major leucyl aminopeptidase of Trypanosoma cruzi (LAPTc) assembles into a homohexamer and belongs to the M17 family of metallopeptidases
   BMC Biochem12, 46-46. PubMed  Europe PubMed DOI