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Literature for peptidase M17.003: PepA aminopeptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Forster,P., Wysocki,J., Abedini,Y., Muller,T., Ye,M., Ferrario,C.M. and Batlle,D.<br>Aminopeptidase A Effect on Angiotensin Peptides and Their Blood Pressure Action<br>Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2024
  2. Balavoine,F., Compere,D., Miege,F., de Mota,N., Keck,M., Fer,M., Christen,A., Martin,E., Roche,D., Llorens-Cortes,C. and Rodeschini,V.<br>Rational design, synthesis and pharmacological characterization of novel aminopeptidase A inhibitors<br>Bioorg Med Chem Lett (2024) 113, 129940-129940. PubMed  Europe PubMed DOI
    3. 2023
  3. Simpson,M.C., Harding,C.J., Czekster,R.M., Remmel,L., Bode,B.E. and Czekster,C.M.<br>Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase<br>Biochemistry (2023) 62, 3188-3205. PubMed  Europe PubMed DOI  PMC  EPMC
    4. 2016
  4. Nguyen Le Minh,P., Nadal,M. and Charlier,D.<br>The trigger enzyme PepA (aminopeptidase A) of Escherichia coli, a transcriptional repressor that generates positive supercoiling<br>FEBS Lett (2016) 590, 1816-1825. PubMed  Europe PubMed DOI
    5. 2013
  5. Kim,J.K., Natarajan,S., Park,H., Huynh,K.H., Lee,S.H., Kim,J.G., Ahn,Y.J. and Kang,L.W.<br>Crystal structure of XoLAP, a leucine aminopeptidase, from Xanthomonas oryzae pv. oryzae<br>J Microbiol (2013) 51, 627-632. PubMed  Europe PubMed DOI  S
  6. Mun,L.S., Tee,T.S. and Puthucheary,S.D.<br>Enzymatic and molecular characterisation of leucine aminopeptidase of Burkholderia pseudomallei<br>BMC Microbiol (2013) 13, 110-110. PubMed  Europe PubMed DOI
    7. 2012
  7. Colloms,S.<br>Leucyl aminopeptidase PepA<br>[ISSN:978-0-12-407743-0] (2012) 3, 1484-1492. DOI
    8. 2011
  8. Circello,B.T., Miller,C.G., Lee,J.H., van der Donk,W.A. and Metcalf,W.W.<br>The antibiotic dehydrophos is converted to a toxic pyruvate analog by peptide bond cleavage in Salmonella enterica<br>Antimicrob Agents Chemother (2011) 55, 3357-3362. PubMed  Europe PubMed DOI
    9. 2010
  9. Bhosale,M., Pande,S., Kumar,A., Kairamkonda,S. and Nandi,D.<br>Characterization of two M17 family members in Escherichia coli, peptidase A and peptidase B<br>Biochem Biophys Res Commun (2010) 395, 76-81. PubMed  Europe PubMed DOI  E
  10. Kale,A., Pijning,T., Sonke,T., Dijkstra,B.W. and Thunnissen,A.M.<br>Crystal structure of the leucine aminopeptidase from Pseudomonas putida reveals the molecular basis for its enantioselectivity and broad substrate specificity<br>J Mol Biol (2010) 398, 703-714. PubMed  Europe PubMed DOI  S
    11. 2009
  11. Huynh,K.H., Natarajan,S., Choi,J., Song,N.H., Kim,J.G., Lee,B.M., Ahn,Y.J. and Kang,L.W.<br>Cloning, expression, crystallization and preliminary X-ray crystallographic analysis of leucine aminopeptidase (LAP) from the pepA gene of Xanthomonas oryzae pv. oryzae<br>Acta Crystallograph Sect F Struct Biol Cryst Commun (2009) 65, 952-955. PubMed  Europe PubMed DOI
  12. Lutfullah,G., Azhar,N., Amin,F., Khan,Z., Azim,M.K., Shouqat,K., Noor,S. and Ali,R.<br>Structural bioinformatics of Vibrio cholerae aminopeptidase A (PepA) monomer<br>Protein Pept Lett (2009) 16, 36-45. PubMed  Europe PubMed DOI
  13. Minh,P.N., Devroede,N., Massant,J., Maes,D. and Charlier,D.<br>Insights into the architecture and stoichiometry of Escherichia coli PepA*DNA complexes involved in transcriptional control and site-specific DNA recombination by atomic force microscopy<br>Nucleic Acids Res (2009) 37, 1463-1476. PubMed  Europe PubMed DOI  PMC  EPMC
    14. 2008
  14. Kazakov,T., Vondenhoff,G.H., Datsenko,K.A., Novikova,M., Metlitskaya,A., Wanner,B.L. and Severinov,K.<br>Escherichia coli peptidase A, B, or N can process translation inhibitor microcin C<br>J Bacteriol (2008) 190, 2607-2610. PubMed  Europe PubMed DOI  PMC  EPMC
    15. 2006
  15. Komeda,H., Hariyama,N. and Asano,Y.<br>L: -Stereoselective amino acid amidase with broad substrate specificity from Brevundimonas diminuta: characterization of a new member of the leucine aminopeptidase family<br>Appl Microbiol Biotechnol (2006) 70, 412-421. PubMed  Europe PubMed DOI
    16. 2005
  16. Reijns,M., Lu,Y., Leach,S. and Colloms,S.D.<br>Mutagenesis of PepA suggests a new model for the Xer/cer synaptic complex<br>Mol Microbiol (2005) 57, 927-941. PubMed  Europe PubMed DOI
    17. 2004
  17. Colloms,S.D.<br>Leucyl aminopeptidase PepA<br>[ISSN:0-12-079610-4] (2004) 2, 905-910.  V
    18. 2001
  18. Behari,J., Stagon,L. and Calderwood,S.B.<br>pepA, a gene mediating pH regulation of virulence genes in Vibrio cholerae<br>J Bacteriol (2001) 183, 178-188. PubMed  Europe PubMed DOI  PMC  EPMC
  19. Suzuki,H., Kamatani,S., Kim,E.S. and Kumagai,H.<br>Aminopeptidases A, B, and N and dipeptidase D are the four cysteinylglycinases of Escherichia coli K-12<br>J Bacteriol (2001) 183, 1489-1490. PubMed  Europe PubMed DOI
  20. Woolwine,S.C., Sprinkle,A.B. and Wozniak,D.J.<br>Loss of Pseudomonas aeruginosa PhpA aminopeptidase activity results in increased algD transcription<br>J Bacteriol (2001) 183, 4674-4679. PubMed  Europe PubMed DOI  PMC  EPMC
    21. 2000
  21. [YEAR:15-9-2000]Charlier,D., Kholti,A., Huysveld,N., Gigot,D., Maes,D., Thia-Toong,T.L. and Glansdorff,N.<br>Mutational analysis of Escherichia coli PepA, a multifunctional DNA-binding aminopeptidase<br>J Mol Biol (15-9-2000) 302, 411-426. PubMed  Europe PubMed DOI
    22. 1999
  22. Gu,Y.Q., Holzer,F.M. and Walling,L.L.<br>Overexpression, purification and biochemical characterization of the wound-induced leucine aminopeptidase of tomato<br>Eur J Biochem (1999) 263, 726-735. PubMed  Europe PubMed DOI
  23. [YEAR:28-9-1999]Strater,N., Sun,L., Kantrowitz,E.R. and Lipscomb,W.N.<br>A bicarbonate ion as a general base in the mechanism of peptide hydrolysis by dizinc leucine aminopeptidase<br>Proc Natl Acad Sci U S A (28-9-1999) 96, 11151-11155. PubMed  Europe PubMed DOI  PMC  EPMC
  24. [YEAR:16-8-1999]Strater,N., Sherratt,D.J. and Colloms,S.D.<br>X-ray structure of aminopeptidase A from Escherichia coli and a model for the nucleoprotein complex in Xer site-specific recombination<br>EMBO J (16-8-1999) 18, 4513-4522. PubMed  Europe PubMed DOI  PMC  EPMC  S
    25. 1997
  25. Alen,C., Sherratt,D.J. and Colloms,S.D.<br>Direct interaction of aminopeptidase A with recombination site DNA in Xer site-specific recombination<br>EMBO J (1997) 16, 5188-5197. PubMed  Europe PubMed DOI  PMC  EPMC
  26. [YEAR:15-11-1997]Yoshikawa,T., Shibata,K., Kaga,M., Sato,Y., Oguchi,H., Totsuka,Y. and Watanabe,T.<br>Development of a polymerase chain reaction assay for Mycoplasma salivarium by using the nucleotide sequence within aminopeptidase My gene<br>FEMS Microbiol Lett (15-11-1997) 156, 281-286. PubMed  Europe PubMed DOI
    27. 1996
  27. [YEAR:1-3-1996]Colloms,S.D., McCulloch,R., Grant,K., Neilson,L. and Sherratt,D.J.<br>Xer-mediated site-specific recombination in vitro<br>EMBO J (1-3-1996) 15, 1172-1181. PubMed  Europe PubMed  PMC  EPMC
    28. 1995
  28. Charlier,D., Gigot,D., Huysveld,N., Roovers,M., Pierard,A. and Glansdorff,N.<br>Pyrimidine regulation of the Escherichia coli and Salmonella typhimurium carAB operons: CarP and integration host factor (IHF) modulate the methylation status of a GATC site present in the control region<br>J Mol Biol (1995) 250, 383-391. PubMed  Europe PubMed DOI
  29. Charlier,D., Hassanzadeh,G., Kholti,A., Gigot,D., Pierard,A. and Glansdorff,N.<br>carP, involved in pyrimidine regulation of the Escherichia coli carbamoylphosphate synthetase operon encodes a sequence-specific DNA-binding protein identical to XerB and PepA, also required for resolution of ColEI multimers<br>J Mol Biol (1995) 250, 392-406. PubMed  Europe PubMed DOI
  30. Shibata,K., Tsuchida,N. and Watanabe,T.<br>Cloning and sequence analysis of the aminopeptidase My gene from Mycoplasma salivarium<br>FEMS Microbiol Lett (1995) 130, 19-24. PubMed  Europe PubMed DOI
    31. 1994
  31. McCulloch,R., Burke,M.E. and Sherratt,D.J.<br>Peptidase activity of Escherichia coli aminopeptidase A is not required for its role in Xer site-specific recombination<br>Mol Microbiol (1994) 12, 241-251. PubMed  Europe PubMed DOI
    32. 1993
  32. [YEAR:1-2-1993]Taylor,A.<br>Aminopeptidases: structure and function<br>FASEB J (1-2-1993) 7, 290-298. PubMed  Europe PubMed
  33. Wood,D.O., Solomon,M.J. and Speed,R.R.<br>Characterization of the Rickettsia prowazekii pepA gene encoding leucine aminopeptidase<br>J Bacteriol (1993) 175, 159-165. PubMed  Europe PubMed  PMC  EPMC
    34. 1989
  34. Stirling,C.J., Colloms,S.D., Collins,J.F., Szatmari,G. and Sherratt,D.J.<br>xerB, an Escherichia coli gene required for plasmid colE1 site-specific recombination, is identical to pepA, encoding aminopeptidase A, a protein with substantial similarity to bovine lens leucine aminopeptidase<br>EMBO J (1989) 8, 1623-1627. PubMed  Europe PubMed  PMC  EPMC

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