Literature for peptidase M12.231: ADAMTS7 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature

(Topics flags: M Mutation, T Target, P Specificity, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Mead,T.J., Bhutada,S., Peruzzi,N., Adegboye,J., Seifert,D.E., Cahill,E., Drinko,J., Donnellan,E., Guggiliam,A., Popovic,Z., Griffin,B., Tran-Lundmark,K. and Apte,S.S.
    ADAMTS7, a target in atherosclerosis, cooperates with its homolog ADAMTS12 to protect against myxomatous valve degeneration
    J Mol Cell Cardiol Plus11, 100288-100288. PubMed  Europe PubMed DOI
  2. 2024
  3. Meibom,D., Wasnaire,P., Beyer,K., Broehl,A., Cancho-Grande,Y., Elowe,N., Henninger,K., Johannes,S., Jungmann,N., Krainz,T., Lindner,N., Maassen,S., MacDonald,B., Menshykau,D., Mittendorf,J., Sanchez,G., Schaefer,M., Stefan,E., Torge,A., Xing,Y. and Zubov,D.
    BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor
    J Med Chem67, 2907-2940. PubMed  Europe PubMed DOI  I
  4. 2023
  5. Chung,A., Reilly,M.P. and Bauer,R.C.
    ADAMTS7: a Novel Therapeutic Target in Atherosclerosis
    Curr Atheroscler Rep25, 447-455. PubMed  Europe PubMed DOI  V
  6. Ma,Z., Mao,C., Jia,Y., Yu,F., Xu,P., Tan,Y., Zou,Q.H., Zhou,X.J., Kong,W. and Fu,Y.
    ADAMTS7-Mediated Complement Factor H Degradation Potentiates Complement Activation to Contributing to Renal Injuries
    J Am Soc Nephrol34, 291-308. PubMed  Europe PubMed DOI
  7. Sharifi,M.A., Wierer,M., Dang,T.A., Milic,J., Moggio,A., Sachs,N., von Scheidt,M., Hinterdobler,J., Muller,P., Werner,J., Stiller,B., Aherrahrou,Z., Erdmann,J., Zaliani,A., Graettinger,M., Reinshagen,J., Gul,S., Gribbon,P., Maegdefessel,L., Bernhagen,J., Sager,H.B., Mann,M., Schunkert,H. and Kessler,T.
    ADAMTS-7 Modulates Atherosclerotic Plaque Formation by Degradation of TIMP-1
    Circ Res133, 674-686. PubMed  Europe PubMed DOI
  8. 2022
  9. Macdonald,B.T., Keshishian,H., Mundorff,C.C., Arduini,A., Lai,D., Bendinelli,K., Popp,N.R., Bhandary,B., Clauser,K.R., Specht,H., Elowe,N.H., Laprise,D., Xing,Y., Kaushik,V.K., Carr,S.A. and Ellinor,P.T.
    TAILS Identifies Candidate Substrates and Biomarkers of ADAMTS7, a Therapeutic Protease Target in Coronary Artery Disease
    Mol Cell Proteomics21, 100223-100223. PubMed  Europe PubMed DOI
  10. 2021
  11. Santamaria,S., Buemi,F., Nuti,E., Cuffaro,D., De Vita,E., Tuccinardi,T., Rossello,A., Howell,S., Mehmood,S., Snijders,A.P. and de Groot,R.
    Development of a fluorogenic ADAMTS-7 substrate
    J Enzyme Inhib Med Chem36, 2160-2169. PubMed  Europe PubMed DOI
  12. 2019
  13. Colige,A., Monseur,C., Crawley,J.T.B., Santamaria,S. and de Groot,R.
    Proteomic discovery of substrates of the cardiovascular protease ADAMTS7
    J Biol Chem294, 8037-8045. PubMed  Europe PubMed DOI  P
  14. 2015
  15. Dubail,J. and Apte,S.S.
    Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics
    Matrix Biol44-46, 24-37. PubMed  Europe PubMed DOI
  16. Pi,L., Jorgensen,M., Oh,S.H., Protopapadakis,Y., Gjymishka,A., Brown,A., Robinson,P., Liu,C., Scott,E.W., Schultz,G.S. and Petersen,B.E.
    A disintegrin and metalloprotease with thrombospondin type I motif 7: a new protease for connective tissue growth factor in hepatic progenitor/oval cell niche
    Am J Pathol185, 1552-1563. PubMed  Europe PubMed DOI
  17. 2013
  18. Hanby,H.A. and Zheng,X.L.
    Biochemistry and physiological functions of ADAMTS7 metalloprotease
    Adv Biochem1, 43-50. PubMed  Europe PubMed DOI  V
  19. Patel,R.S. and Ye,S.
    ADAMTS7: a promising new therapeutic target in coronary heart disease
    Expert Opin Ther Targets17, 863-867. PubMed  Europe PubMed DOI  T
  20. Pu,X., Xiao,Q., Kiechl,S., Chan,K., Ng,F.L., Gor,S., Poston,R.N., Fang,C., Patel,A., Senver,E.C., Shaw-Hawkins,S., Willeit,J., Liu,C., Zhu,J., Tucker,A.T., Xu,Q., Caulfield,M.J. and Ye,S.
    ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant
    Am J Hum Genet92, 366-374. PubMed  Europe PubMed DOI  M
  21. 2012
  22. Du,Y., Gao,C., Liu,Z., Wang,L., Liu,B., He,F., Zhang,T., Wang,Y., Wang,X., Xu,M., Luo,G.Z., Zhu,Y., Xu,Q., Wang,X. and Kong,W.
    Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by miR-29 repression mediates vascular smooth muscle calcification
    Arterioscler Thromb Vasc Biol32, 2580-2588. PubMed  Europe PubMed DOI
  23. Liu,C.
    ADAMTS7
    [ISSN:978-0-12-407744-7]3, 1180-1186. DOI
  24. 2010
  25. Guo,F., Lai,Y., Tian,Q., Lin,E.A., Kong,L. and Liu,C.
    Granulin-epithelin precursor binds directly to ADAMTS-7 and ADAMTS-12 and inhibits their degradation of cartilage oligomeric matrix protein
    Arthritis Rheum62, 2023-2036. PubMed  Europe PubMed DOI
  26. Wang,L., Wang,X. and Kong,W.
    ADAMTS-7, a novel proteolytic culprit in vascular remodeling
    Sheng Li Xue Bao62, 285-294. PubMed  Europe PubMed
  27. 2009
  28. Liu,C.J.
    The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis
    Nat Clin Pract Rheumatol5, 38-45. PubMed  Europe PubMed DOI
  29. 2008
  30. Luan,Y., Kong,L., Howell,D.R., Ilalov,K., Fajardo,M., Bai,X.H., Di Cesare,P.E., Goldring,M.B., Abramson,S.B. and Liu,C.J.
    Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin
    Osteoarthritis Cartilage16, 1413-1420. PubMed  Europe PubMed DOI
  31. 2007
  32. Borchert,N., Becker-Pauly,C., Wagner,A., Fischer,P., Stocker,W. and Brattig,N.W.
    Identification and characterization of onchoastacin, an astacin-like metalloproteinase from the filaria Onchocerca volvulus
    Microbes Infect9, 498-506. PubMed  Europe PubMed DOI
  33. 2006
  34. Liu,C.J., Kong,W., Ilalov,K., Yu,S., Xu,K., Prazak,L., Fajardo,M., Sehgal,B. and Di Cesare,P.E.
    ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein
    FASEB J20, 988-990. PubMed  Europe PubMed DOI
  35. 2004
  36. [YEAR:21-6-2004]Somerville,R.P., Longpre,J.M., Apel,E.D., Lewis,R.M., Wang,L.W., Sanes,J.R., Leduc,R. and Apte,S.S.
    ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domain
    J Biol Chem279, 35159-35175. PubMed  Europe PubMed DOI
  37. 1999
  38. [YEAR:3-9-1999]Hurskainen,T.L., Hirohata,S., Seldin,M.F. and Apte,S.S.
    ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family
    J Biol Chem274, 25555-25563. PubMed  Europe PubMed DOI