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Literature for peptidase M12.231: ADAMTS7 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature

(Topics flags: M Mutation, T Target, P Specificity, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Martin,D.R., Sardelli,G., Burkhard,T., Fowkes,M.M., Minns,A.F., Moschini,R., Del Corso,A., de Groot,R., Apte,S.S. and Santamaria,S.
    Characterization of ADAMTS9 proteoglycanase activity: comparison with ADAMTS1, ADAMTS4 and ADAMTS5
    J Biol Chem (2025) , 110301-110301. PubMed  Europe PubMed DOI
  2. Mead,T.J., Bhutada,S., Peruzzi,N., Adegboye,J., Seifert,D.E., Cahill,E., Drinko,J., Donnellan,E., Guggiliam,A., Popovic,Z., Griffin,B., Tran-Lundmark,K. and Apte,S.S.
    ADAMTS7, a target in atherosclerosis, cooperates with its homolog ADAMTS12 to protect against myxomatous valve degeneration
    J Mol Cell Cardiol Plus (2025) 11, 100288-100288. PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2024
  3. Meibom,D., Wasnaire,P., Beyer,K., Broehl,A., Cancho-Grande,Y., Elowe,N., Henninger,K., Johannes,S., Jungmann,N., Krainz,T., Lindner,N., Maassen,S., MacDonald,B., Menshykau,D., Mittendorf,J., Sanchez,G., Schaefer,M., Stefan,E., Torge,A., Xing,Y. and Zubov,D.
    BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor
    J Med Chem (2024) 67, 2907-2940. PubMed  Europe PubMed DOI  PMC  EPMC  I
    4. 2023
  4. Chung,A., Reilly,M.P. and Bauer,R.C.
    ADAMTS7: a Novel Therapeutic Target in Atherosclerosis
    Curr Atheroscler Rep (2023) 25, 447-455. PubMed  Europe PubMed DOI  V
  5. Ma,Z., Mao,C., Jia,Y., Yu,F., Xu,P., Tan,Y., Zou,Q.H., Zhou,X.J., Kong,W. and Fu,Y.
    ADAMTS7-Mediated Complement Factor H Degradation Potentiates Complement Activation to Contributing to Renal Injuries
    J Am Soc Nephrol (2023) 34, 291-308. PubMed  Europe PubMed DOI
  6. Sharifi,M.A., Wierer,M., Dang,T.A., Milic,J., Moggio,A., Sachs,N., von Scheidt,M., Hinterdobler,J., Muller,P., Werner,J., Stiller,B., Aherrahrou,Z., Erdmann,J., Zaliani,A., Graettinger,M., Reinshagen,J., Gul,S., Gribbon,P., Maegdefessel,L., Bernhagen,J., Sager,H.B., Mann,M., Schunkert,H. and Kessler,T.
    ADAMTS-7 Modulates Atherosclerotic Plaque Formation by Degradation of TIMP-1
    Circ Res (2023) 133, 674-686. PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2022
  7. Macdonald,B.T., Keshishian,H., Mundorff,C.C., Arduini,A., Lai,D., Bendinelli,K., Popp,N.R., Bhandary,B., Clauser,K.R., Specht,H., Elowe,N.H., Laprise,D., Xing,Y., Kaushik,V.K., Carr,S.A. and Ellinor,P.T.
    TAILS Identifies Candidate Substrates and Biomarkers of ADAMTS7, a Therapeutic Protease Target in Coronary Artery Disease
    Mol Cell Proteomics (2022) 21, 100223-100223. PubMed  Europe PubMed DOI  PMC  EPMC
    8. 2021
  8. Santamaria,S., Buemi,F., Nuti,E., Cuffaro,D., De Vita,E., Tuccinardi,T., Rossello,A., Howell,S., Mehmood,S., Snijders,A.P. and de Groot,R.
    Development of a fluorogenic ADAMTS-7 substrate
    J Enzyme Inhib Med Chem (2021) 36, 2160-2169. PubMed  Europe PubMed DOI  PMC  EPMC
    9. 2019
  9. Colige,A., Monseur,C., Crawley,J.T.B., Santamaria,S. and de Groot,R.
    Proteomic discovery of substrates of the cardiovascular protease ADAMTS7
    J Biol Chem (2019) 294, 8037-8045. PubMed  Europe PubMed DOI  P
    10. 2015
  10. Dubail,J. and Apte,S.S.
    Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics
    Matrix Biol (2015) 44-46, 24-37. PubMed  Europe PubMed DOI
  11. Pi,L., Jorgensen,M., Oh,S.H., Protopapadakis,Y., Gjymishka,A., Brown,A., Robinson,P., Liu,C., Scott,E.W., Schultz,G.S. and Petersen,B.E.
    A disintegrin and metalloprotease with thrombospondin type I motif 7: a new protease for connective tissue growth factor in hepatic progenitor/oval cell niche
    Am J Pathol (2015) 185, 1552-1563. PubMed  Europe PubMed DOI
    12. 2013
  12. Hanby,H.A. and Zheng,X.L.
    Biochemistry and physiological functions of ADAMTS7 metalloprotease
    Adv Biochem (2013) 1, 43-50. PubMed  Europe PubMed DOI  PMC  EPMC  V
  13. Patel,R.S. and Ye,S.
    ADAMTS7: a promising new therapeutic target in coronary heart disease
    Expert Opin Ther Targets (2013) 17, 863-867. PubMed  Europe PubMed DOI  T
  14. Pu,X., Xiao,Q., Kiechl,S., Chan,K., Ng,F.L., Gor,S., Poston,R.N., Fang,C., Patel,A., Senver,E.C., Shaw-Hawkins,S., Willeit,J., Liu,C., Zhu,J., Tucker,A.T., Xu,Q., Caulfield,M.J. and Ye,S.
    ADAMTS7 cleavage and vascular smooth muscle cell migration is affected by a coronary-artery-disease-associated variant
    Am J Hum Genet (2013) 92, 366-374. PubMed  Europe PubMed DOI  M
    15. 2012
  15. Du,Y., Gao,C., Liu,Z., Wang,L., Liu,B., He,F., Zhang,T., Wang,Y., Wang,X., Xu,M., Luo,G.Z., Zhu,Y., Xu,Q., Wang,X. and Kong,W.
    Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by miR-29 repression mediates vascular smooth muscle calcification
    Arterioscler Thromb Vasc Biol (2012) 32, 2580-2588. PubMed  Europe PubMed DOI
  16. Liu,C.
    ADAMTS7
    [ISSN:978-0-12-407744-7] (2012) 3, 1180-1186. DOI
    17. 2010
  17. Guo,F., Lai,Y., Tian,Q., Lin,E.A., Kong,L. and Liu,C.
    Granulin-epithelin precursor binds directly to ADAMTS-7 and ADAMTS-12 and inhibits their degradation of cartilage oligomeric matrix protein
    Arthritis Rheum (2010) 62, 2023-2036. PubMed  Europe PubMed DOI  PMC  EPMC
  18. Wang,L., Wang,X. and Kong,W.
    ADAMTS-7, a novel proteolytic culprit in vascular remodeling
    Sheng Li Xue Bao (2010) 62, 285-294. PubMed  Europe PubMed
    19. 2009
  19. Liu,C.J.
    The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis
    Nat Clin Pract Rheumatol (2009) 5, 38-45. PubMed  Europe PubMed DOI
    20. 2008
  20. Luan,Y., Kong,L., Howell,D.R., Ilalov,K., Fajardo,M., Bai,X.H., Di Cesare,P.E., Goldring,M.B., Abramson,S.B. and Liu,C.J.
    Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin
    Osteoarthritis Cartilage (2008) 16, 1413-1420. PubMed  Europe PubMed DOI  PMC  EPMC
    21. 2007
  21. Borchert,N., Becker-Pauly,C., Wagner,A., Fischer,P., Stocker,W. and Brattig,N.W.
    Identification and characterization of onchoastacin, an astacin-like metalloproteinase from the filaria Onchocerca volvulus
    Microbes Infect (2007) 9, 498-506. PubMed  Europe PubMed DOI
    22. 2006
  22. Liu,C.J., Kong,W., Ilalov,K., Yu,S., Xu,K., Prazak,L., Fajardo,M., Sehgal,B. and Di Cesare,P.E.
    ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein
    FASEB J (2006) 20, 988-990. PubMed  Europe PubMed DOI  PMC  EPMC
    23. 2004
  23. [YEAR:21-6-2004]Somerville,R.P., Longpre,J.M., Apel,E.D., Lewis,R.M., Wang,L.W., Sanes,J.R., Leduc,R. and Apte,S.S.
    ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domain
    J Biol Chem (21-6-2004) 279, 35159-35175. PubMed  Europe PubMed DOI
    24. 1999
  24. [YEAR:3-9-1999]Hurskainen,T.L., Hirohata,S., Seldin,M.F. and Apte,S.S.
    ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family
    J Biol Chem (3-9-1999) 274, 25555-25563. PubMed  Europe PubMed DOI

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