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Literature for peptidase M12.215: ADAM15 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: A Assay, T Target, I Inhibitor, R Splicing, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2023
  1. Calligaris,M., Yang,C.Y., Bonelli,S., Spano,D.P., Muller,S.A., Lichtenthaler,S.F., Troeberg,L. and Scilabra,S.D.
    Identification of membrane proteins regulated by ADAM15 by SUSPECS proteomics
    Front Mol Biosci10, 1162504-1162504. PubMed  Europe PubMed DOI  K
  2. Puig-Blasco,L., Piotrowski,K.B., Michaelsen,S.R., Bager,N.S., Areskeviciutie,A., Thorseth,M.L., Sun,X.F., Keller,U.A.D., Kristensen,B.W., Madsen,D.H., Gnosa,S.P. and Kveiborg,M.
    Loss of cancer cell-derived ADAM15 alters the tumor microenvironment in colorectal tumors
    Int J Cancer153, 2068-2081. PubMed  Europe PubMed DOI
    3. 2022
  3. Gruba,N., Musielak,M., Rejmak,W. and Lesner,A.
    Detection of ADAM15 in urine from patients with bladder cancer
    Anal Biochem654, 114805-114805. PubMed  Europe PubMed DOI
  4. Yang,C.Y., Bonelli,S., Calligaris,M., Carreca,A.P., Muller,S.A., Lichtenthaler,S.F., Troeberg,L. and Scilabra,S.D.
    Quantitative Proteomics Reveals That ADAM15 Can Have Proteolytic-Independent Functions in the Steady State
    Membranes (Basel)12, PubMed  Europe PubMed DOI
    5. 2021
  5. Janczi,T., Meier,F., Fehrl,Y., Kinne,R.W., Bohm,B. and Burkhardt,H.
    A Novel Pro-Inflammatory Mechanosensing Pathway Orchestrated by the Disintegrin Metalloproteinase ADAM15 in Synovial Fibroblasts
    Cells10, PubMed  Europe PubMed DOI
  6. Wang,X., Rojas-Quintero,J., Zhang,D., Nakajima,T., Walker,K.H., Peh,H.Y., Li,Y., Fucci,Q.A., Tesfaigzi,Y. and Owen,C.A.
    A disintegrin and metalloproteinase domain-15 deficiency leads to exaggerated cigarette smoke-induced chronic obstructive pulmonary disease (COPD)-like disease in mice
    Mucosal Immunol14, 342-356. PubMed  Europe PubMed DOI  K
    7. 2018
  7. Yang,X., Meegan,J.E., Jannaway,M., Coleman,D.C. and Yuan,S.Y.
    A disintegrin and metalloproteinase 15-mediated glycocalyx shedding contributes to vascular leakage during inflammation
    Cardiovasc Res114, 1752-1763. PubMed  Europe PubMed DOI  K
    8. 2012
  8. Rawlings,N.D.
    ADAM15 peptidase
    [ISSN:978-0-12-407744-7]3, 1122-1125. DOI
    9. 2011
  9. Bultmann,A., Li,Z., Wagner,S., Gawaz,M., Ungerer,M., Langer,H., May,A.E. and Munch,G.
    Loss of protease activity of ADAM15 abolishes protective effects on plaque progression in atherosclerosis
    Int J Cardiol152, 382-385. PubMed  Europe PubMed DOI
    10. 2010
  10. Lu,D., Scully,M., Kakkar,V. and Lu,X.
    ADAM-15 disintegrin-like domain structure and function
    Toxins2, 2411-2427. PubMed  Europe PubMed DOI
  11. Sun,C., Wu,M.H., Guo,M., Day,M.L., Lee,E.S. and Yuan,S.Y.
    ADAM15 regulates endothelial permeability and neutrophil migration via Src/ERK1/2 signalling
    Cardiovasc Res87, 348-355. PubMed  Europe PubMed DOI
    12. 2009
  12. Kleino,I., Ortiz,R.M., Yritys,M., Huovila,A.P. and Saksela,K.
    Alternative splicing of ADAM15 regulates its interactions with cellular SH3 proteins
    J Cell Biochem108, 877-885. PubMed  Europe PubMed DOI
  13. Lucas,N., Najy,A.J. and Day,M.L.
    The therapeutic potential of ADAM15
    Curr Pharm Des15, 2311-2318. PubMed  Europe PubMed DOI  V  T
  14. Lucas,N. and Day,M.L.
    The role of the disintegrin metalloproteinase ADAM15 in prostate cancer progression
    J Cell Biochem106, 967-974. PubMed  Europe PubMed DOI  T
  15. Maretzky,T., Le Gall,S.M., Worpenberg-Pietruk,S., Eder,J., Overall,C.M., Huang,X.Y., Poghosyan,Z., Edwards,D.R. and Blobel,C.P.
    Src stimulates fibroblast growth factor receptor-2 shedding by an ADAM15 splice variant linked to breast cancer
    Cancer Res69, 4573-4576. PubMed  Europe PubMed DOI  R
  16. Maretzky,T., Yang,G., Ouerfelli,O., Overall,C.M., Worpenberg,S., Hassiepen,U., Eder,J. and Blobel,C.P.
    Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays
    Biochem J420, 105-113. PubMed  Europe PubMed DOI  A  I
    17. 2008
  17. Charrier-Hisamuddin,L., Laboisse,C.L. and Merlin,D.
    ADAM-15: a metalloprotease that mediates inflammation
    FASEB J22, 641-653. PubMed  Europe PubMed DOI  V
    18. 2007
  18. Kleino,I., Ortiz,R.M. and Huovila,A.P.
    ADAM15 gene structure and differential alternative exon use in human tissues
    BMC Mol Biol8, 90-90. PubMed  Europe PubMed DOI
    19. 2006
  19. Kuefer,R., Day,K.C., Kleer,C.G., Sabel,M.S., Hofer,M.D., Varambally,S., Zorn,C.S., Chinnaiyan,A.M., Rubin,M.A. and Day,M.L.
    ADAM15 Disintegrin Is Associated with Aggressive Prostate and Breast Cancer Disease
    Neoplasia8, 319-329. PubMed  Europe PubMed DOI
    20. 2005
  20. [YEAR:9-9-2005]Charrier,L., Yan,Y., Driss,A., Laboisse,C.L., Sitaraman,S.V. and Merlin,D.
    ADAM-15 inhibits wound healing in human intestinal epithelial cell monolayers
    Am J Physiol Gastrointest Liver Physiol288, G346-G353. PubMed  Europe PubMed DOI
  21. Komiya,K., Enomoto,H., Inoki,I., Okazaki,S., Fujita,Y., Ikeda,E., Ohuchi,E., Matsumoto,H., Toyama,Y. and Okada,Y.
    Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis
    Arthritis Res Ther7, R1158-R1173. PubMed  Europe PubMed DOI
  22. Langer,H., May,A.E., Bultmann,A. and Gawaz,M.
    ADAM 15 is an adhesion receptor for platelet GPIIb-IIIa and induces platelet activation
    Thromb Haemost94, 555-561. PubMed  Europe PubMed DOI
    23. 2004
  23. [YEAR:26-8-2004]Schafer,B., Marg,B., Gschwind,A. and Ullrich,A.
    Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival
    J Biol Chem279, 47929-47938. PubMed  Europe PubMed DOI
  24. Wolfsberg,T.G. and White,J.M.
    ADAM metalloproteinases
    [ISSN:0-12-079610-4]2, 709-714.  V
    25. 2003
  25. [YEAR:15-8-2003]Fourie,A.M., Coles,F., Moreno,V. and Karlsson,L.
    Catalytic activity of ADAM8, ADAM15, and MDC-L (ADAM28) on synthetic peptide substrates and in ectodomain cleavage of CD23
    J Biol Chem278, 30469-30477. PubMed  Europe PubMed DOI
  26. Horiuchi,K., Weskamp,G., Lum,L., Hammes,H.P., Cai,H., Brodie,T.A., Ludwig,T., Chiusaroli,R., Baron,R., Preissner,K.T., Manova,K. and Blobel,C.P.
    Potential role for ADAM15 in pathological neovascularization in mice
    Mol Cell Biol23, 5614-5624. PubMed  Europe PubMed DOI
  27. [YEAR:3-10-2003]Shimizu,E., Yasui,A., Matsuura,K., Hijiya,N., Higuchi,Y. and Yamamoto,S.
    Structure and expression of the murine ADAM 15 gene and its splice variants, and difference of interaction between their cytoplasmic domains and Src family proteins
    Biochem Biophys Res Commun309, 779-785. PubMed  Europe PubMed DOI
    28. 2002
  28. [YEAR:1-10-2002]Ham,C., Levkau,B., Raines,E.W. and Herren,B.
    ADAM15 is an adherens junction molecule whose surface expression can be driven by VE-cadherin
    Exp Cell Res279, 239-247. PubMed  Europe PubMed DOI
  29. [YEAR:13-9-2002]Martin,J., Eynstone,L.V., Davies,M., Williams,J.D. and Steadman,R.
    The role of ADAM 15 in glomerular mesangial cell migration
    J Biol Chem277, 33683-33689. PubMed  Europe PubMed DOI  I
  30. [YEAR:15-2-2002]Poghosyan,Z., Robbins,S.M., Houslay,M.D., Webster,A., Murphy,G. and Edwards,D.R.
    Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases
    J Biol Chem277, 4999-5007. PubMed  Europe PubMed DOI
    31. 2001
  31. Bohm,B.B., Aigner,T., Blobel,C.P., Kalden,J.R. and Burkhardt,H.
    Highly enhanced expression of the disintegrin metalloproteinase MDC15 (metargidin) in rheumatoid synovial tissue
    Arthritis Rheum44, 2046-2054. PubMed  Europe PubMed DOI
  32. [YEAR:15-11-2001]Herren,B., Garton,K.J., Coats,S., Bowen-Pope,D.F., Ross,R. and Raines,E.W.
    ADAM15 overexpression in NIH3T3 cells enhances cell-cell interactions
    Exp Cell Res271, 152-160. PubMed  Europe PubMed DOI
    33. 2000
  33. Karkkainen,I., Karhu,R. and Huovila,A.P.J.
    Assignment of the ADAM15 gene to human chromosome band 1q21.3 by in situ hybridization
    Cytogenet Cell Genet88, 206-207. PubMed  Europe PubMed
    34. 1999
  34. Nath,D., Slocombe,P.M., Stephens,P.E., Warn,A., Hutchinson,G.R., Yamada,K.M., Docherty,A.J. and Murphy,G.
    Interaction of metargidin (ADAM-15) with alphavbeta3 and alpha5beta1 integrins on different haemopoietic cells
    J Cell Sci112, 579-587. PubMed  Europe PubMed
    35. 1998
  35. [YEAR:2-10-1998]Lum,L., Reid,M.S. and Blobel,C.P.
    Intracellular maturation of the mouse metalloprotease disintegrin MDC15
    J Biol Chem273, 26236-26247. PubMed  Europe PubMed DOI
    36. 1997
  36. Herren,B., Raines,E.W. and Ross,R.
    Expression of a disintegrin-like protein in cultured human vascular cells and in vivo
    FASEB J11, 173-180. PubMed  Europe PubMed
    37. 1996
  37. Kratzschmar,J., Lum,L. and Blobel,C.P.
    Metargidin, a membrane-anchored metalloprotease-disintegrin protein with an RGD integrin binding sequence
    J Biol Chem271, 4593-4596. PubMed  Europe PubMed DOI

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