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Literature for family M10

Family

Summary Holotypes Alignment Tree Genomes Structure Literature H-seq M-seq Architecture

M10A

Summary Holotypes Alignment Tree Genomes Literature

M10B

Summary Holotypes Alignment Tree Genomes Literature

M10C

Summary Holotypes Alignment Tree Genomes Literature

(Topics flags: A Assay, S Structure, M Mutation, I Inhibitor, P Specificity, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Parsons,C. and Fournier,G.P.
    Horizontal transfer of matrix metalloproteinase genes links early animal and microbial evolution
    Biol Direct (2025) 20, 107-107. PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2021
  2. Iwaki,H., Kamiya,M., Kawatani,M., Kojima,R., Yamasoba,T. and Urano,Y.
    Fluorescence Probes for Imaging Basic Carboxypeptidase Activity in Living Cells with High Intracellular Retention
    Anal Chem (2021) 93, 3470-3476. PubMed  Europe PubMed DOI
    3. 2020
  3. Gimeno,A., Beltran-Debon,R., Mulero,M., Pujadas,G. and Garcia-Vallve,S.
    Understanding the variability of the S1' pocket to improve matrix metalloproteinase inhibitor selectivity profiles
    Drug Discov Today (2020) 25, 38-57. PubMed  Europe PubMed DOI  P
  4. Li,F., Chen,J., Leier,A., Marquez-Lago,T., Liu,Q., Wang,Y., Revote,J., Smith,A.I., Akutsu,T., Webb,G.I., Kurgan,L. and Song,J.
    DeepCleave: a deep learning predictor for caspase and matrix metalloprotease substrates and cleavage sites
    Bioinformatics (2020) 36, 1057-1065. PubMed  Europe PubMed DOI
  5. Meraz-Cruz,N., Vadillo-Ortega,F., Jimenez-Garduno,A.M. and Ortega,A.
    Thermal stability of human matrix metalloproteinases
    Heliyon (2020) 6, e03865-e03865. PubMed  Europe PubMed DOI  PMC  EPMC
  6. Ran,T., Li,W., Sun,B., Xu,M., Qiu,S., Xu,D.Q., He,J. and Wang,W.
    Crystal structure of mature myroilysin and implication for its activation mechanism
    Int J Biol Macromol (2020) 156, 1556-1564. PubMed  Europe PubMed DOI  S
  7. Triebel,J., Schauer,N., Zamora,M., Moreno-Vega,A.I., Escalera,G.M., Clapp,C. and Bertsch,T.
    Matrix metalloproteases and cathepsin D in human serum do not cleave prolactin to generate vasoinhibin
    Clin Lab (2020) 66 PubMed  Europe PubMed DOI
    8. 2019
  8. Fakhouri,A.S. and Leight,J.L.
    Measuring global cellular matrix metalloproteinase and metabolic activity in 3D hydrogels
    J Vis Exp (2019) PubMed  Europe PubMed DOI  A
  9. Fedonin,G.G., Eroshkin,A., Cieplak,P., Matveev,E.V., Ponomarev,G.V., Gelfand,M.S., Ratnikov,B.I. and Kazanov,M.D.
    Predictive models of protease specificity based on quantitative protease-activity profiling data
    Biochim Biophys Acta Proteins Proteom (2019) 1867, 140253-140253. PubMed  Europe PubMed DOI
  10. Fields,G.B.
    The rebirth of matrix metalloproteinase inhibitors: moving beyond the dogma
    Cells (2019) 8 PubMed  Europe PubMed DOI  I
  11. Fischer,T. and Riedl,R.
    Inhibitory antibodies designed for matrix metalloproteinase modulation
    Molecules (2019) 24 PubMed  Europe PubMed DOI
  12. Fischer,T., Senn,N. and Riedl,R.
    Design and structural evolution of matrix metalloproteinase inhibitors
    Chemistry (2019) 25, 7960-7980. PubMed  Europe PubMed DOI  I
  13. Santamaria,S. and de Groot,R.
    Monoclonal antibodies against metzincin targets
    Br J Pharmacol (2019) 176, 52-66. PubMed  Europe PubMed DOI
  14. Sanyal,S., Amin,S.A., Adhikari,N. and Jha,T.
    QSAR modelling on a series of arylsulfonamide-based hydroxamates as potent MMP-2 inhibitors
    SAR QSAR Environ Res (2019) 30, 247-263. PubMed  Europe PubMed DOI  I
    15. 2018
  15. Malara,A., Ligi,D., Di Buduo,C.A., Mannello,F. and Balduini,A.
    Sub-cellular localization of metalloproteinases in megakaryocytes
    Cells (2018) 7 PubMed  Europe PubMed DOI
  16. Misra,S., Talwar,P., Kumar,A., Kumar,P., Sagar,R., Vibha,D., Pandit,A.K., Gulati,A., Kushwaha,S. and Prasad,K.
    Association between matrix metalloproteinase family gene polymorphisms and risk of ischemic stroke: a systematic review and meta-analysis of 29 studies
    Gene (2018) 672, 180-194. PubMed  Europe PubMed DOI  M
  17. Tokmina-Roszyk,M. and Fields,G.B.
    Dissecting MMP P10' and P11' subsite sequence preferences, utilizing a positional scanning, combinatorial triple-helical peptide library
    J Biol Chem (2018) 293, 16661-16676. PubMed  Europe PubMed DOI  P
    18. 2017
  18. Cieplak,P. and Strongin,A.Y.
    Matrix metalloproteinases - from the cleavage data to the prediction tools and beyond
    Biochim Biophys Acta (2017) 1864, 1952-1963. PubMed  Europe PubMed DOI  P
  19. Schwenck,J., Maier,F.C., Kneilling,M., Wiehr,S. and Fuchs,K.
    Non-invasive in vivo fluorescence optical imaging of inflammatory MMP activity using an activatable fluorescent imaging agent
    J Vis Exp (2017) , 55180-55180. PubMed  Europe PubMed DOI  L
    20. 2016
  20. Eckhard,U., Huesgen,P.F., Schilling,O., Bellac,C.L., Butler,G.S., Cox,J.H., Dufour,A., Goebeler,V., Kappelhoff,R., Keller,U.A., Klein,T., Lange,P.F., Marino,G., Morrison,C.J., Prudova,A., Rodriguez,D., Starr,A.E., Wang,Y. and Overall,C.M.
    Active site specificity profiling of the matrix metalloproteinase family: proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic peptide cleavage analyses
    Matrix Biol (2016) 49, 37-60. PubMed  Europe PubMed DOI  P
  21. Eckhard,U., Huesgen,P.F., Schilling,O., Bellac,C.L., Butler,G.S., Cox,J.H., Dufour,A., Goebeler,V., Kappelhoff,R., auf dem Keller,U., Klein,T., Lange,P.F., Marino,G., Morrison,C.J., Prudova,A., Rodriguez,D., Starr,A.E., Wang,Y. and Overall,C.M.
    Active site specificity profiling datasets of matrix metalloproteinases (MMPs) 1, 2, 3, 7, 8, 9, 12, 13 and 14
    Data Brief (2016) 7, 299-310. PubMed  Europe PubMed DOI  PMC  EPMC  P
  22. Fields,G.B. and Stawikowski,M.J.
    Imaging matrix metalloproteinase activity implicated in breast cancer progression
    Methods Mol Biol (2016) 1406, 303-329. PubMed  Europe PubMed DOI  L
  23. Muvva,C., Patra,S. and Venkatesan,S.
    MMpI: A WideRange of Available Compounds of Matrix Metalloproteinase Inhibitors
    PLoS ONE (2016) 11, e0159321-e0159321. PubMed  Europe PubMed DOI  I
    24. 2015
  24. Cathcart,J.M. and Cao,J.
    MMP Inhibitors: Past, present and future
    Front Biosci Landmark (2015) 20, 1164-1178.  I
  25. Kukreja,M., Shiryaev,S.A., Cieplak,P., Muranaka,N., Routenberg,D.A., Chernov,A.V., Kumar,S., Remacle,A.G., Smith,J.W., Kozlov,I.A. and Strongin,A.Y.
    High-throughput multiplexed peptide-centric profiling illustrates both substrate cleavage redundancy and specificity in the MMP family
    Chem Biol (2015) 22, 1122-1133. PubMed  Europe PubMed DOI  P
  26. Kumar,S., Ratnikov,B.I., Kazanov,M.D., Smith,J.W. and Cieplak,P.
    CleavPredict: a platform for reasoning about matrix metalloproteinases proteolytic events
    PLoS ONE (2015) 10, e0127877-e0127877. PubMed  Europe PubMed DOI  PMC  EPMC
    27. 2014
  27. Li,N.G., Tang,Y.P., Duan,J.A. and Shi,Z.H.
    Matrix metalloproteinase inhibitors: a patent review (2011 - 2013)
    Expert Opin Ther Pat (2014) 24, 1039-1052. PubMed  Europe PubMed DOI  I
  28. Vandenbroucke,R.E. and Libert,C.
    Is there new hope for therapeutic matrix metalloproteinase inhibition?
    Nat Rev Drug Discov (2014) 13, 904-927. PubMed  Europe PubMed DOI  I
    29. 2013
  29. Dufour,A. and Overall,C.M.
    Missing the target: matrix metalloproteinase antitargets in inflammation and cancer
    Trends Pharmacol Sci (2013) 34, 233-242. PubMed  Europe PubMed DOI
  30. Matusiak,N., Waarde,A., Bischoff,R., Oltenfreiter,R., Wiele,C., Dierckx,R.A. and Elsinga,P.H.
    Probes for non-invasive matrix metalloproteinase-targeted imaging with PET and SPECT
    Curr Pharm Des (2013) 19, 4647-4672. PubMed  Europe PubMed DOI  L
    31. 2012
  31. Auld,D.S.
    Catalytic mechanisms for metallopeptidases
    [ISSN:978-0-12-407744-7] (2012) 3, 370-396. DOI
  32. Gupta,S.P. and Patil,V.M.
    Specificity of binding with matrix metalloproteinases
    EXS (2012) 103, 35-56. PubMed  Europe PubMed DOI  I
  33. Iyer,R.P., Patterson,N.L., Fields,G.B. and Lindsey,M.L.
    The history of matrix metalloproteinases: milestones, myths, and misperceptions
    Am J Physiol Heart Circ Physiol (2012) 303, H919-H930. PubMed  Europe PubMed DOI
  34. Marino,G. and Funk,C.
    Matrix metalloproteinases in plants: a brief overview
    Physiol Plant (2012) 145, 196-202. PubMed  Europe PubMed DOI
  35. Ndinguri,M.W., Bhowmick,M., Tokmina-Roszyk,D., Robichaud,T.K. and Fields,G.B.
    Peptide-based selective inhibitors of matrix metalloproteinase-mediated activities
    Molecules (2012) 17, 14230-14248. PubMed  Europe PubMed DOI  I
  36. Patil,V.M. and Gupta,S.P.
    Quantitative structure-activity relationship studies on sulfonamide-based MMP inhibitors
    EXS (2012) 103, 177-208. PubMed  Europe PubMed DOI  I
  37. Sbardella,D., Fasciglione,G.F., Gioia,M., Ciaccio,C., Tundo,G.R., Marini,S. and Coletta,M.
    Human matrix metalloproteinases: an ubiquitarian class of enzymes involved in several pathological processes
    Mol Aspects Med (2012) 33, 119-208. PubMed  Europe PubMed DOI  V
    38. 2010
  38. Dorman,G., Cseh,S., Hajdu,I., Barna,L., Konya,D., Kupai,K., Kovacs,L. and Ferdinandy,P.
    Matrix metalloproteinase inhibitors: a critical appraisal of design principles and proposed therapeutic utility
    Drugs (2010) 70, 949-964. PubMed  Europe PubMed DOI  I
  39. Jacobsen,J.A., Major Jourden,J.L., Miller,M.T. and Cohen,S.M.
    To bind zinc or not to bind zinc: an examination of innovative approaches to improved metalloproteinase inhibition
    Biochim Biophys Acta (2010) 1803, 72-94. PubMed  Europe PubMed DOI  I
  40. Tallant,C., Marrero,A. and Gomis-Ruth,F.X.
    Matrix metalloproteinases: fold and function of their catalytic domains
    Biochim Biophys Acta (2010) 1803, 20-28. PubMed  Europe PubMed DOI  S
    41. 2009
  41. Gomis-Ruth,F.X.
    Catalytic domain architecture of metzincin metalloproteases
    J Biol Chem (2009) 284, 15353-15357. PubMed  Europe PubMed DOI  PMC  EPMC
    42. 2008
  42. Page-McCaw,A.
    Remodeling the model organism: matrix metalloproteinase functions in invertebrates
    Semin Cell Dev Biol (2008) 19, 14-23. PubMed  Europe PubMed DOI  PMC  EPMC
  43. Yiotakis,A. and Dive,V.
    Third-generation MMP inhibitors: Recent advances in the development of highly selective inhibitors
    The Cancer Degradome: Proteases and Cancer Biol (2008) , 811-825. DOI  I
    44. 2007
  44. Ra,H.J. and Parks,W.C.
    Control of matrix metalloproteinase catalytic activity
    Matrix Biol (2007) 26, 587-596. PubMed  Europe PubMed DOI  PMC  EPMC  V
    45. 2006
  45. Fisher,J.F. and Mobashery,S.
    Recent advances in MMP inhibitor design
    Cancer Metastasis Rev (2006) 25, 115-136. PubMed  Europe PubMed DOI  V
  46. [YEAR:3-1-2006]Nagase,H., Visse,R. and Murphy,G.
    Structure and function of matrix metalloproteinases and TIMPs
    Cardiovasc Res (3-1-2006) 69, 562-573. PubMed  Europe PubMed DOI  V
  47. [YEAR:11-1-2006]Peterson,J.T.
    The importance of estimating the therapeutic index in the development of matrix metalloproteinase inhibitors
    Cardiovasc Res (11-1-2006) 69, 677-687. PubMed  Europe PubMed DOI  V  I
    48. 2005
  48. Cuniasse,P., Devel,L., Makaritis,A., Beau,F., Georgiadis,D., Matziari,M., Yiotakis,A. and Dive,V.
    Future challenges facing the development of specific active-site-directed synthetic inhibitors of MMPs
    Biochimie (2005) 87, 393-402. PubMed  Europe PubMed DOI  I
  49. [YEAR:29-6-2005]Gupta,S.P. and Kumaran,S.
    A quantitative structure-activity relationship study on some series of anthranilic acid-based matrix metalloproteinase inhibitors
    Bioorg Med Chem (29-6-2005) 13, 5454-5462. PubMed  Europe PubMed DOI  I
  50. Kontogiorgis,C.A., Papaioannou,P. and Hadjipavlou-Litina,D.J.
    Matrix metalloproteinase inhibitors: a review on pharmacophore mapping and (Q)SARs results
    Curr Med Chem (2005) 12, 339-355. PubMed  Europe PubMed  V  I
  51. Lapiere,C.
    Tadpole collagenase, the single parent of such a large family
    Biochimie (2005) 87, 243-247. PubMed  Europe PubMed DOI  V
  52. Rao,B.G.
    Recent developments in the design of specific matrix metalloproteinase inhibitors aided by structural and computational studies
    Curr Pharm Des (2005) 11, 295-322. PubMed  Europe PubMed DOI  V  I
    53. 2004
  53. [YEAR:19-1-2004]Butler,G.S., Tam,E.M. and Overall,C.M.
    The canonical methionine 392 of matrix metalloproteinase 2 (gelatinase A) is not required for catalytic efficiency or structural integrity: probing the role of the methionine-turn in the metzincin metalloprotease superfamily
    J Biol Chem (19-1-2004) 279, 15615-15620. PubMed  Europe PubMed DOI  I
  54. Skiles,J.W., Gonnella,N.C. and Jeng,A.Y.
    The design, structure, and clinical update of small molecular weight matrix metalloproteinase inhibitors
    Curr Med Chem (2004) 11, 2911-2977. PubMed  Europe PubMed  V  I
    55. 2003
  55. Maskos,K. and Bode,W.
    Structural basis of matrix metalloproteinases and tissue inhibitors of metalloproteinases
    Mol Biotechnol (2003) 25, 241-266. PubMed  Europe PubMed DOI  S
    56. 2000
  56. Heath,E.I. and Grochow,L.B.
    Clinical potential of matrix metalloprotease inhibitors in cancer therapy
    Drugs (2000) 59, 1043-1055. PubMed  Europe PubMed  V  I
    57. 1999
  57. Bode,W., Fernandez-Catalan,C., Tschesche,H., Grams,F., Nagase,H. and Maskos,K.
    Structural properties of matrix metalloproteinases
    Cell Mol Life Sci (1999) 55, 639-652. PubMed  Europe PubMed DOI  S
    58. 1998
  58. Massova,I., Kotra,L.P., Fridman,R. and Mobashery,S.
    Matrix metalloproteinases: structures, evolution, and diversification
    FASEB J (1998) 12, 1075-1095. PubMed  Europe PubMed
  59. [YEAR:10-9-1998]Pikul,S., McDow Dunham,K.L., Almstead,N.G., De,B., Natchus,M.G., Anastasio,M.V., McPhail,S.J., Snider,C.E., Taiwo,Y.O., Rydel,T., Dunaway,C.M., Gu,F. and Mieling,G.E.
    Discovery of potent, achiral matrix metalloproteinase inhibitors
    J Med Chem (10-9-1998) 41, 3568-3571. PubMed  Europe PubMed DOI  I
  60. [YEAR:10-7-1998]Yang,M. and Kurkinen,M.
    Cloning and characterization of a novel matrix metalloproteinase (MMP), CMMP, from chicken embryo fibroblasts. CMMP, Xenopus XMMP, and human MMP19 have a conserved unique cysteine in the catalytic domain
    J Biol Chem (10-7-1998) 273, 17893-17900. PubMed  Europe PubMed DOI
    61. 1997
  61. Chambers,A.F. and Matrisian,L.M.
    Changing views of the role of matrix metalloproteinases in metastasis
    J Natl Cancer Inst (1997) 89, 1260-1270. PubMed  Europe PubMed
  62. Murphy,G. and Knauper,V.
    Relating matrix metalloproteinase structure to function: why the "hemopexin" domain?
    Matrix Biol (1997) 15, 511-518. PubMed  Europe PubMed DOI
  63. Nagase,H.
    Activation mechanisms of matrix metalloproteinases
    Biol Chem (1997) 378, 151-160. PubMed  Europe PubMed
  64. Wojtowicz-Praga,S.M., Dickson,R.B. and Hawkins,M.J.
    Matrix metalloproteinase inhibitors
    Invest New Drugs (1997) 15, 61-75. PubMed  Europe PubMed DOI  V  I
    65. 1996
  65. Moura-da-Silva,A.M., Theakston,R.D. and Crampton,J.M.
    Evolution of disintegrin cysteine-rich and mammalian matrix-degrading metalloproteinases: gene duplication and divergence of a common ancestor rather than convergent evolution
    J Mol Evol (1996) 43, 263-269. PubMed  Europe PubMed
    66. 1995
  66. Stocker,W., Grams,F., Baumann,U., Reinemer,P., Gomis-Ruth,F.X., McKay,D.B. and Bode,W.
    The metzincins - topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidases
    Protein Sci (1995) 4, 823-840. PubMed  Europe PubMed DOI  PMC  EPMC
  67. Stocker,W. and Bode,W.
    Structural features of a superfamily of zinc-endopeptidases: the metzincins
    Curr Opin Struct Biol (1995) 5, 383-390. PubMed  Europe PubMed DOI
    68. 1993
  68. Bode,W., Gomis-Ruth,F.X. and Stockler,W.
    Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins'
    FEBS Lett (1993) 331, 134-140. PubMed  Europe PubMed DOI  S
    69. 1991
  69. Woessner,J.F., Jr.
    Matrix metalloproteinases and their inhibitors in connective tissue remodeling
    FASEB J (1991) 5, 2145-2154. PubMed  Europe PubMed
    70. 1990
  70. Springman,E.B., Angleton,E.L., Birkedal-Hansen,H. and Van Wart,H.E.
    Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation
    Proc Natl Acad Sci U S A (1990) 87, 364-368. PubMed  Europe PubMed DOI  PMC  EPMC
  71. Van Wart,H.E. and Birkedal-Hansen,H.
    The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family
    Proc Natl Acad Sci U S A (1990) 87, 5578-5582. PubMed  Europe PubMed DOI  PMC  EPMC

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