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Literature for peptidase M10.060: epralysin

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

(Topics flags: I Inhibitor, E Expression, L Localization, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Sinha,A. and Kelly,A.L.
    Techniques to Detect and Quantify the Bacterial Metalloprotease AprX in Bovine Milk: A Review
    Compr Rev Food Sci Food Saf (2026) 25, e70415-e70415. PubMed  Europe PubMed DOI  PMC  EPMC  L
    2. 2025
  2. Liu,S., Shao,L., Dong,Y., Gong,J., Yang,X., Li,F., Xu,X. and Wang,H.
    Hydrolysis of myofibrillar proteins by protease AprA secreted from Pseudomonas fragi: Preference for degrading Ala-linked peptide bonds
    Food Chem (2025) 479, 143756-143756. PubMed  Europe PubMed DOI
  3. Sandri,A. and Boschi,F.
    Exploring Proteases as Alternative Molecular Targets to Tackle Inflammation in Cystic Fibrosis Respiratory Infections
    Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC  V
    4. 2024
  4. Keim,K., Bhattacharya,M., Crosby,H.A., Jenul,C., Mills,K., Schurr,M. and Horswill,A.
    Polymicrobial interactions between Staphylococcus aureus and Pseudomonas aeruginosa promote biofilm formation and persistence in chronic wound infections
    bioRxiv (2024) PubMed  Europe PubMed DOI  PMC  EPMC
    5. 2023
  5. Potok,P., Kola,A., Valensin,D., Capdevila,M. and Potocki,S.
    Copper Forms a PPII Helix-Like Structure with the Catalytic Domains of Bacterial Zinc Metalloproteases
    Inorg Chem (2023) 62, 18425-18439. PubMed  Europe PubMed DOI  PMC  EPMC
    6. 2020
  6. Zhang,C., Bijl,E., Muis,K.E. and Hettinga,K.
    Stability of fat globules in UHT milk during proteolysis by the AprX protease from Pseudomonas fluorescens and by plasmin
    J Dairy Sci (2020) 103, 179-190. PubMed  Europe PubMed DOI
    7. 2017
  7. Lee,S.A., Jang,S.H., Kim,B.H., Shibata,T., Yoo,J., Jung,Y., Kawabata,S.I. and Lee,B.L.
    Insecticidal activity of the metalloprotease AprA occurs through suppression of host cellular and humoral immunity
    Dev Comp Immunol (2017) 81, 116-126. PubMed  Europe PubMed DOI
    8. 2016
  8. Stuknyte,M., Decimo,M., Colzani,M., Silvetti,T., Brasca,M., Cattaneo,S., Aldini,G. and De Noni,I.
    Extracellular thermostable proteolytic activity of the milk spoilage bacterium Pseudomonas fluorescens PS19 on bovine caseins
    J Dairy Sci (2016) 99, 4188-4195. PubMed  Europe PubMed DOI
    9. 2015
  9. Baur,C., Krewinkel,M., Kutzli,I., Kranz,B., von Neubeck,M., Huptas,C., Wenning,M., Scherer,S., Stoeckel,M., Hinrichs,J., Stressler,T. and Fischer,L.
    Isolation and characterisation of a heat-resistant peptidase from Pseudomonas panacis withstanding general UHT processes
    Int Dairy J (2015) 49, 46-55. DOI
  10. Casilag,F., Lorenz,A., Krueger,J., Klawonn,F., Weiss,S. and Haussler,S.
    The LasB elastase of Pseudomonas aeruginosa acts in concert with alkaline protease AprA to prevent flagellin-mediated immune recognition
    Infect Immun (2015) 84, 162-171. PubMed  Europe PubMed DOI
  11. Chen,C.M., Liu,J.J., Chou,C.W., Lai,C.H. and Wu,L.T.
    RpA, an extracellular protease similar to the metalloprotease of serralysin family, is required for pathogenicity of Ralstonia pickettii
    J Appl Microbiol (2015) 119, 1101-1111. PubMed  Europe PubMed DOI
  12. Mateos,A., Guyard-Nicodeme,M., Bagliniere,F., Jardin,J., Gaucheron,F., Dary,A., Humbert,G. and Gaillard,J.-L.
    Proteolysis of milk proteins by AprX, an extracellular protease identified in Pseudomonas LBSA1 isolated from bulk raw milk, and implications for the stability of UHT milk
    Int Dairy J (2015) 49, 78-88. DOI
    13. 2014
  13. Pel,M.J., Van Dijken,A.J., Bardoel,B.W., Seidl,M.F., van der Ent,S., van Strijp,J.A. and Pieterse,C.M.
    Pseudomonas syringae evades host immunity by degrading flagellin monomers with alkaline protease AprA
    Mol Plant Microbe Interact (2014) 27, 603-610. PubMed  Europe PubMed DOI
    14. 2012
  14. Laarman,A.J., Bardoel,B.W., Ruyken,M., Fernie,J., Milder,F.J., van Strijp,J.A. and Rooijakkers,S.H.
    Pseudomonas aeruginosa alkaline protease blocks complement activation via the classical and lectin pathways
    J Immunol (2012) 188, 386-393. PubMed  Europe PubMed DOI
  15. Takahashi,K.
    Epralysin
    [ISSN:978-0-12-407744-7] (2012) 3, 875-877. DOI
    16. 2010
  16. Jankiewicz,U., Szawlowska,U. and Sobanska,M.
    Biochemical characterization of an alkaline metallopeptidase secreted by a Pseudomonas fluorescens isolated from soil
    J Basic Microbiol (2010) 50, 125-134. PubMed  Europe PubMed DOI
  17. Rahman,R.N., Geok,L.P., Wong,C.F., Basri,M. and Salleh,A.B.
    Molecular investigation of a gene encoding organic solvent-tolerant alkaline protease from Pseudomonas aeruginosa strain K
    J Basic Microbiol (2010) 50, 143-149. PubMed  Europe PubMed DOI  E
    18. 2009
  18. Zhang,W.W., Hu,Y.H., Wang,H.L. and Sun,L.
    Identification and characterization of a virulence-associated protease from a pathogenic Pseudomonas fluorescens strain
    Vet Microbiol (2009) 139, 183-188. PubMed  Europe PubMed DOI
    19. 2008
  19. Dufour,D., Nicodeme,M., Perrin,C., Driou,A., Brusseaux,E., Humbert,G., Gaillard,J.L. and Dary,A.
    Molecular typing of industrial strains of Pseudomonas spp. isolated from milk and genetical and biochemical characterization of an extracellular protease produced by one of them
    Int J Food Microbiol (2008) 125, 188-196. PubMed  Europe PubMed DOI
    20. 2006
  20. Kim,S.J., Park,R.Y., Kang,S.M., Choi,M.H., Kim,C.M. and Shin,S.H.
    Pseudomonas aeruginosa alkaline protease can facilitate siderophore-mediated iron-uptake via the proteolytic cleavage of transferrins
    Biol Pharm Bull (2006) 29, 2295-2300. PubMed  Europe PubMed DOI
  21. Maunsell,B., Adams,C. and O'Gara,F.
    Complex regulation of AprA metalloprotease in Pseudomonas fluorescens M114: evidence for the involvement of iron, the ECF sigma factor, PbrA and pseudobactin M114 siderophore
    Microbiology (Reading) (2006) 152, 29-42. PubMed  Europe PubMed DOI
    22. 2004
  22. Anderson,L.M., Stockwell,V.O. and Loper,J.E.
    An extracellular protease of Pseudomonas fluorescens inactivates antibiotics of Pantoea agglomerans
    Phytopathology (2004) 94, 1228-1234. PubMed  Europe PubMed DOI
  23. Takahashi,K.
    Epralysin
    [ISSN:0-12-079610-4] (2004) 2, 586-588.  V
    24. 1999
  24. Kumeta,H., Hoshino,T., Goda,T., Okayama,T., Shimada,T., Ohgiya,S., Matsuyama,H. and Ishizaki,K.
    Identification of a member of the serralysin family isolated from a psychrotrophic bacterium, Pseudomonas fluorescens 114
    Biosci Biotechnol Biochem (1999) 63, 1165-1170. PubMed  Europe PubMed
  25. Kumura,H., Murata,S., Hoshino,T., Mikawa,K. and Shimazaki,K.
    Autolysis of the proteinase from Pseudomonas fluorescens
    J Dairy Sci (1999) 82, 2078-2083. PubMed  Europe PubMed DOI
  26. Schokker,E.P. and Van Boekel,M.A.J.S.
    Effect of Ca2+ and Zn2+ ions on inactivation between 30 and 0 degrees of the extracellular proteinase from Pseudomonas fluorescens 22F
    Milchwissenschaft (1999) 54, 436-438.
    27. 1998
  27. Liao,C.H. and McCallus,D.E.
    Biochemical and genetic characterization of an extracellular protease from Pseudomonas fluorescens CY091
    Appl Environ Microbiol (1998) 64, 914-921. PubMed  Europe PubMed  PMC  EPMC
  28. Schokker,E.P. and van Boekel,M.A.
    Mechanism and kinetics of inactivation at 40-70 degrees C of the extracellular proteinase from Pseudomonas fluorescens 22F
    J Dairy Res (1998) 65, 261-272. PubMed  Europe PubMed DOI
    29. 1997
  29. Kim,H.J., Tamanoue,Y., Jeohn,G.H., Iwamatsu,A., Yokota,A., Kim,Y.T., Takahashi,T. and Takahashi,K.
    Purification and characterization of an extracellular metalloprotease from Pseudomonas fluorescens
    J Biochem (1997) 121, 82-88. PubMed  Europe PubMed
    30. 1994
  30. Hamamoto,T., Kaneda,M., Horikoshi,K. and Kudo,T.
    Characterization of a protease from a psychrotroph, Pseudomonas fluorescens 114
    Appl Environ Microbiol (1994) 60, 3878-3880. PubMed  Europe PubMed  PMC  EPMC
    31. 1993
  31. Kumura,H., Mikawa,K. and Saito,Z.
    Purification and some properties of proteinase from Pseudomonas fluorescens No. 33
    J Dairy Res (1993) 60, 229-237. PubMed  Europe PubMed
    32. 1987
  32. Diermayr,P., Kroll,S. and Klostermeyer,H.
    Influence of EDTA and metal ions on a metalloproteinase from Pseudomonas fluorescens biotype I
    Biol Chem Hoppe Seyler (1987) 368, 57-61. PubMed  Europe PubMed  I
  33. Diermayr,P., Kroll,S. and Klostermeyer,H.
    Mechanisms of heat inactivation of a proteinase from Pseudomonas fluorescens biotype I
    J Dairy Res (1987) 54, 51-60. PubMed  Europe PubMed
    34. 1976
  34. [YEAR:15-9-1976]Juan,S.M. and Cazzulo,J.J.
    The extracellular protease from Pseudomonas fluorescens
    Experientia (15-9-1976) 32, 1120-1122. PubMed  Europe PubMed

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