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Literature for peptidase M10.030: matrix metallopeptidase-28

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Inhibitors Pharma

(Topics flags: R Splicing, K Knockout, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Liu,Y., Liao,S., Yuan,B., Liu,X., Yu,W., Zhan,H., Jiang,Y., Li,X., Li,R. and Tan,J.
    MMP28 promotes tumorigenesis and gemcitabine resistance in pancreatic cancer by promoting glycolysis through interaction with SND1
    Biochem Pharmacol (2026) 243, 117556-117556. PubMed  Europe PubMed DOI  K
    2. 2020
  2. Zhou,K., Li,Y., Xu,Y. and Guo,R.
    Circulating Matrix Metalloproteinase-28 Levels Are Related to GRACE Scores and Short-Term Outcomes in Patients with Acute Myocardial Infarction
    Biomed Res Int (2020) 2020, 9206703-9206703. PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2017
  3. Manicone,A.M., Gharib,S.A., Gong,K.Q., Eddy,W.E., Long,M.E., Frevert,C.W., Altemeier,W.A., Parks,W.C. and Houghton,A.M.
    Matrix metalloproteinase-28 is a key contributor to emphysema pathogenesis
    Am J Pathol (2017) 187, 1288-1300. PubMed  Europe PubMed DOI  K
    4. 2013
  4. Ma,Y., Halade,G.V., Zhang,J., Ramirez,T.A., Levin,D., Voorhees,A., Jin,Y.F., Han,H.C., Manicone,A.M. and Lindsey,M.L.
    Matrix metalloproteinase-28 deletion exacerbates cardiac dysfunction and rupture after myocardial infarction in mice by inhibiting M2 macrophage activation
    Circ Res (2013) 112, 675-688. PubMed  Europe PubMed DOI  PMC  EPMC
  5. Spinale,F.G.
    Epilysin (matrix metalloproteinase-28) joins the matrix metalloproteinase team on the field of postmyocardial infarction remodeling
    Circ Res (2013) 112, 579-582. PubMed  Europe PubMed DOI
    6. 2012
  6. Lohi,J., Parks,W.C. and Manicone,A.M.
    Matrix metallopeptidase-28/epilysin
    [ISSN:978-0-12-407744-7] (2012) 3, 845-850. DOI
  7. Ma,Y., Chiao,Y.A., Zhang,J., Manicone,A.M., Jin,Y.F. and Lindsey,M.L.
    Matrix metalloproteinase-28 deletion amplifies inflammatory and extracellular matrix responses to cardiac aging
    Microsc Microanal (2012) 18, 81-90. PubMed  Europe PubMed DOI  K
    8. 2011
  8. Manicone,A.M., Harju-Baker,S., Johnston,L.K., Chen,A.J. and Parks,W.C.
    Epilysin (matrix metalloproteinase-28) contributes to airway epithelial cell survival
    Respir Res (2011) 12, 144-144. PubMed  Europe PubMed DOI
    9. 2010
  9. Rodgers,U.R. and Clark,I.M.
    Expression of recombinant MMP-28 in mammalian cells
    Methods Mol Biol (2010) 622, 55-65. PubMed  Europe PubMed DOI  E
    10. 2009
  10. Gruber,H.E., Ingram,J.A., Hoelscher,G.L., Zinchenko,N., Norton,H.J. and Hanley,E.N., Jr.
    Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs
    Arthritis Res Ther (2009) 11, R184-R184. PubMed  Europe PubMed DOI
  11. Heiskanen,T.J., Illman,S.A., Lohi,J. and Keski-Oja,J.
    Epilysin (MMP-28) is deposited to the basolateral extracellular matrix of epithelial cells
    Matrix Biol (2009) 28, 74-83. PubMed  Europe PubMed DOI
  12. Manicone,A.M., Birkland,T.P., Lin,M., Betsuyaku,T., van Rooijen,N., Lohi,J., Keski-Oja,J., Wang,Y., Skerrett,S.J. and Parks,W.C.
    Epilysin (MMP-28) restrains early macrophage recruitment in Pseudomonas aeruginosa pneumonia
    J Immunol (2009) 182, 3866-3876. PubMed  Europe PubMed DOI  PMC  EPMC
  13. Rodgers,U.R., Kevorkian,L., Surridge,A.K., Waters,J.G., Swingler,T.E., Culley,K., Illman,S., Lohi,J., Parker,A.E. and Clark,I.M.
    Expression and function of matrix metalloproteinase (MMP)-28
    Matrix Biol (2009) 28, 263-272. PubMed  Europe PubMed DOI  PMC  EPMC
    14. 2008
  14. Illman,S.A., Lohi,J. and Keski-Oja,J.
    Epilysin (MMP-28) - structure, expression and potential functions
    Exp Dermatol (2008) 17, 897-907. PubMed  Europe PubMed DOI  V
  15. Werner,S.R., Dotzlaf,J.E. and Smith,R.C.
    MMP-28 as a regulator of myelination
    BMC Neurosci (2008) 9, 83-83. PubMed  Europe PubMed DOI  PMC  EPMC
    16. 2007
  16. Werner,S.R., Mescher,A.L., Neff,A.W., King,M.W., Chaturvedi,S., Duffin,K.L., Harty,M.W. and Smith,R.C.
    Neural MMP-28 expression precedes myelination during development and peripheral nerve repair
    Dev Dyn (2007) 236, 2852-2864. PubMed  Europe PubMed DOI
    17. 2006
  17. [YEAR:15-9-2006]Illman,S.A., Lehti,K., Keski-Oja,J. and Lohi,J.
    Epilysin (MMP-28) induces TGF-beta mediated epithelial to mesenchymal transition in lung carcinoma cells
    J Cell Sci (15-9-2006) 119, 3856-3865. PubMed  Europe PubMed DOI
  18. [YEAR:24-5-2006]Lin,M.H., Liu,S.Y., Su,H.J. and Liu,Y.C.
    Functional role of matrix metalloproteinase-28 in the oral squamous cell carcinoma
    Oral Oncol (24-5-2006) 42, 907-913. PubMed  Europe PubMed DOI
    19. 2005
  19. Reno,F., Sabbatini,M., Stella,M., Magliacani,G. and Cannas,M.
    Effect of in vitro mechanical compression on epilysin (matrix metalloproteinase-28) expression in hypertrophic scars
    Wound Repair Regen (2005) 13, 255-261. PubMed  Europe PubMed DOI
    20. 2004
  20. Lohi,J. and Parks,W.C.
    Epilysin
    [ISSN:0-12-079610-4] (2004) 2, 568-570.  V
    21. 2003
  21. [YEAR:1-10-2003]Illman,S.A., Keski-Oja,J., Parks,W.C. and Lohi,J.
    The mouse matrix metalloproteinase, epilysin (MMP-28), is alternatively spliced and processed by a furin-like proprotein convertase
    Biochem J (1-10-2003) 375, 191-197. PubMed  Europe PubMed DOI  PMC  EPMC  R
    22. 2002
  22. Saarialho-Kere,U., Kerkela,E., Jahkola,T., Suomela,S., Keski-Oja,J. and Lohi,J.
    Epilysin (MMP-28) expression is associated with cell proliferation during epithelial repair
    J Invest Dermatol (2002) 119, 14-21. PubMed  Europe PubMed DOI
    23. 2001
  23. [YEAR:5-9-2001]Ilman,S.A., Keski-Oja,J. and Lohi,J.
    Promoter characterization of the human and mouse epilysin (MMP-28) genes
    Gene (5-9-2001) 275, 185-194. PubMed  Europe PubMed DOI
  24. [YEAR:30-3-2001]Lohi,J., Wilson,C.L., Roby,J.D. and Parks,W.C.
    Epilysin, a novel human matrix metalloproteinase (MMP-28) expressed in testis and keratinocytes and in response to injury
    J Biol Chem (30-3-2001) 276, 10134-10144. PubMed  Europe PubMed DOI
  25. [YEAR:7-3-2001]Marchenko,G.N. and Strongin,A.Y.
    MMP-28, a new human matrix metalloproteinase with an unusual cysteine-switch sequence is widely expressed in tumors
    Gene (7-3-2001) 265, 87-93. PubMed  Europe PubMed DOI

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