Literature for peptidase M08.001: leishmanolysin

(Topics flags: S Structure, T Target, K Knockout, P Specificity, I Inhibitor, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2024
1. Hernandez-Ramirez,V.I., Matus-Meza,A.S., Oviedo,N., Magos-Castro,M.A., Osorio-Trujillo,C., Salazar-Villatoro,L., Constantino-Jonapa,L.A. and Talamas-Rohana,P.
   Exploration of the Binding Site of Arachidonic Acid in gp63 of Leishmania mexicana and in Orthologous Proteins in Clinically Important Parasites
   Pathogens13, PubMed  Europe PubMed DOI
2023
2. Devsani,N., Vemula,D. and Bhandari,V.
   The glycoprotein gp63- a potential pan drug target for developing new antileishmanial agents
   Biochimie207, 75-82. PubMed  Europe PubMed DOI  V
3. Oliveira,S.S.C., Correia,C.A., Santos,V.S., Da Cunha,E.F.F., de Castro,A.A., Ramalho,T.C., Devereux,M., McCann,M., Branquinha,M.H. and Santos,A.L.S.
   Silver(I) and Copper(II) 1,10-Phenanthroline-5,6-dione Complexes as Promising Antivirulence Strategy against Leishmania: Focus on Gp63 (Leishmanolysin)
   Trop Med Infect Dis8, PubMed  Europe PubMed DOI  I
4. Pereira-Filho,A.A., Queiroz,D.C., Saab,N.A.A., D'Avila Pessoa,G.C., Koerich,L.B., Pereira,M.H., Sant'Anna,M.R.V., Araujo,R.N., Bartholomeu,D.C. and Gontijo,N.F.
   Evasion of the complement system by Leishmania through the uptake of C4bBP, a complement regulatory protein, and probably by the action of GP63 on C4b molecules deposited on parasite surface
   Acta Trop242, 106908-106908. PubMed  Europe PubMed DOI
2022
5. Guay-Vincent,M.M., Matte,C., Berthiaume,A.M., Olivier,M., Jaramillo,M. and Descoteaux,A.
   Revisiting Leishmania GP63 host cell targets reveals a limited spectrum of substrates
   PLoS Pathog18, e1010640-e1010640. PubMed  Europe PubMed DOI
6. Sen,S., Bal,S.K., Yadav,S., Mishra,P., G,V.V., Rastogi,R. and Mukhopadhyay,C.K.
   Intracellular pathogen Leishmania intervenes in iron loading into ferritin by cleaving chaperones in host macrophages as an iron acquisition strategy
   J Biol Chem298, 102646-102646. PubMed  Europe PubMed DOI
2021
7. Antonia,A.L., Barnes,A.B., Martin,A.T., Wang,L. and Ko,D.C.
   Variation in Leishmania chemokine suppression driven by diversification of the GP63 virulence factor
   PLoS Negl Trop Dis15, e0009224-e0009224. PubMed  Europe PubMed DOI
8. da Silva Lira Filho,A., Fajardo,E.F., Chang,K.P., Clement,P. and Olivier,M.
   Leishmania Exosomes/Extracellular Vesicles Containing GP63 Are Essential for Enhance Cutaneous Leishmaniasis Development Upon Co-Inoculation of Leishmania amazonensis and Its Exosomes
   Front Cell Infect Microbiol11, 709258-709258. PubMed  Europe PubMed DOI
9. Khatoon,S., Aroosh,A., Islam,A., Kalsoom,S., Ahmad,F., Hameed,S., Abbasi,S.W., Yasinzai,M. and Naseer,M.M.
   Novel coumarin-isatin hybrids as potent antileishmanial agents: Synthesis, in silico and in vitro evaluations
   Bioorg Chem110, 104816-104816. PubMed  Europe PubMed DOI
2020
10. Mercado-Camargo,J., Cervantes-Ceballos,L., Vivas-Reyes,R., Pedretti,A., Serrano-Garcia,M.L. and Gomez-Estrada,H.
    Homology Modeling of Leishmanolysin (gp63) from Leishmania panamensis and Molecular Docking of Flavonoids
    ACS Omega5, 14741-14749. PubMed  Europe PubMed DOI
2019
11. Rebello,K.M., Uehara,L.A., Ennes-Vidal,V., Garcia-Gomes,A.S., Britto,C., Azambuja,P., Menna-Barreto,R.F.S., Santos,A.L.S., Branquinha,M.H. and D'Avila-Levy,C.M.
    Participation of Trypanosoma cruzi gp63 molecules on the interaction with Rhodnius prolixus
    Parasitology146, 1075-1082. PubMed  Europe PubMed DOI
12. Yorek,M.S., Poudel,B., Mazgaeen,L., Pope,R.M., Wilson,M.E. and Gurung,P.
    Leishmania major degrades murine CXCL1 - an immune evasion strategy
    PLoS Negl Trop Dis13, e0007533-e0007533. PubMed  Europe PubMed DOI  P
2018
13. Estrada-Figueroa,L.A., Diaz-Gandarilla,J.A., Hernandez-Ramirez,V.I., Arrieta-Gonzalez,M.M., Osorio-Trujillo,C., Rosales-Encina,J.L., Toledo-Leyva,A. and Talamas-Rohana,P.
    Leishmania mexicana gp63 is the enzyme responsible for cyclooxygenase (COX) activity in this parasitic protozoa
    Biochimie151, 73-84. PubMed  Europe PubMed DOI
14. Marshall,S., Kelly,P.H., Singh,B.K., Pope,R.M., Kim,P., Zhanbolat,B., Wilson,M.E. and Yao,C.
    Extracellular release of virulence factor major surface protease via exosomes in Leishmania infantum promastigotes
    Parasit Vectors11, 355-355. PubMed  Europe PubMed DOI
2017
15. Khan,H., Nadhman,A., Azam,S.S., Anees,M., Khan,I., Ullah,I., Sohail,M.F., Shahnaz,G. and Yasinzai,M.
    In-vitro antileishmanial potential of peptide drug hirudin
    Chem Biol Drug Des89, 67-73. PubMed  Europe PubMed DOI
16. Sutter,A., Antunes,D., Silva-Almeida,M., Costa,M.G.S. and Caffarena,E.R.
    Structural insights into leishmanolysins encoded on chromosome 10 of Leishmania (Viannia) braziliensis
    Mem Inst Oswaldo Cruz112, 617-625. PubMed  Europe PubMed DOI
2016
17. Casgrain,P.A., Martel,C., McMaster,W.R., Mottram,J.C., Olivier,M. and Descoteaux,A.
    Cysteine peptidase B regulates Leishmania mexicana virulence through the modulation of GP63 expression
    PLoS Pathog12, e1005658-e1005658. PubMed  Europe PubMed DOI
18. Medina,L.S., Souza,B.A., Queiroz,A., Guimaraes,L.H., Lima Machado,P.R., M Carvalho,E., Wilson,M.E. and Schriefer,A.
    The gp63 gene cluster is highly polymorphic in natural Leishmania (Viannia) braziliensis populations, but functional sites are conserved
    PLoS ONE11, e0163284-e0163284. PubMed  Europe PubMed DOI
19. Waghmare,S., Buxi,A., Nandurkar,Y., Shelke,A. and Chavan,R.
    In silico sequence analysis, homology modeling and function annotation of leishmanolysin from Leishmania donovani
    J Parasitic Dis40, 1266-1269. DOI
2015
20. Isnard,A., Christian,J.G., Kodiha,M., Stochaj,U., McMaster,W.R. and Olivier,M.
    Impact of Leishmania infection on host macrophage nuclear physiology and nucleopore complex integrity
    PLoS Pathog11, e1004776-e1004776. PubMed  Europe PubMed DOI
21. Llewellyn,M.S., Messenger,L.A., Luquetti,A.O., Garcia,L., Torrico,F., Tavares,S.B., Cheaib,B., Derome,N., Delepine,M., Baulard,C., Deleuze,J.F., Sauer,S. and Miles,M.A.
    Deep sequencing of the Trypanosoma cruzi GP63 surface proteases reveals diversity and diversifying selection among chronic and congenital Chagas disease patients
    PLoS Negl Trop Dis9, e0003458-e0003458. PubMed  Europe PubMed DOI
22. Shio,M.T., Christian,J.G., Jung,J.Y., Chang,K.P. and Olivier,M.
    PKC/ROS-mediated NLRP3 inflammasome activation is attenuated by Leishmania zinc-metalloprotease during infection
    PLoS Negl Trop Dis9, e0003868-e0003868. PubMed  Europe PubMed DOI
2014
23. Hassani,K., Shio,M.T., Martel,C., Faubert,D. and Olivier,M.
    Absence of metalloprotease GP63 alters the protein content of Leishmania exosomes
    PLoS ONE9, e95007-e95007. PubMed  Europe PubMed DOI  K
24. Iorns,E., Gunn,W., Erath,J., Rodriguez,A., Zhou,J. and Benzinou,M.
    Replication attempt: "Effect of BMAP-28 antimicrobial peptides on Leishmania major promastigote and amastigote growth: role of leishmanolysin in parasite survival"
    PLoS ONE9, e114614-e114614. PubMed  Europe PubMed DOI
2013
25. Calixto,P.H., Bitar,M., Ferreira,K.A., Abrahao,O., Jr., Lages-Silva,E., Franco,G.R., Ramirez,L.E. and Pedrosa,A.L.
    Gene identification and comparative molecular modeling of a Trypanosoma rangeli major surface protease
    J Mol Model19, 3053-3064. PubMed  Europe PubMed DOI
2012
26. Isnard,A., Shio,M.T. and Olivier,M.
    Impact of Leishmania metalloprotease GP63 on macrophage signaling
    Front Cell Infect Microbiol2, 72-72. PubMed  Europe PubMed DOI
27. Olivier,M. and Isnard,A.
    Leishmanolysin
    [ISSN:978-0-12-407744-7]3, 1231-1237. DOI
28. Olivier,M., Atayde,V.D., Isnard,A., Hassani,K. and Shio,M.T.
    Leishmania virulence factors: focus on the metalloprotease GP63
    Microbes Infect14, 1377-1389. PubMed  Europe PubMed DOI  V
29. Reyes-Uribe,P., Pereira-Dos-Santos,T., De Jesus,J.B., Mesquita-Rodrigues,C., Arevalo,J., Cupolillo,E. and Cuervo,P.
    Comparative zymographic analysis of metallopeptidase of Leishmania (Viannia) peruviana and Leishmania (Viannia) braziliensis isolates from Peru
    Parasitol Int61, 513-519. PubMed  Europe PubMed DOI
2011
30. Lynn,M.A., Kindrachuk,J., Marr,A.K., Jenssen,H., Pante,N., Elliott,M.R., Napper,S., Hancock,R.E. and McMaster,W.R.
    Effect of BMAP-28 antimicrobial peptides on Leishmania major promastigote and amastigote growth: role of leishmanolysin in parasite survival
    PLoS Negl Trop Dis5, e1141-e1141. PubMed  Europe PubMed DOI
31. Ma,L., Chen,K., Meng,Q., Liu,Q., Tang,P., Hu,S. and Yu,J.
    An evolutionary analysis of trypanosomatid GP63 proteases
    Parasitol Res109, 1075-1084. PubMed  Europe PubMed DOI
2010
32. Contreras,I., Gomez,M.A., Nguyen,O., Shio,M.T., McMaster,R.W. and Olivier,M.
    Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63
    PLoS Pathog6, e1001148-e1001148. PubMed  Europe PubMed DOI
33. Ferreira,K.A., Ruiz,J.C., Dias,F.C., Lages-Silva,E., Tosi,L.R., Ramirez,L.E. and Pedrosa,A.L.
    Genome survey sequence analysis and identification of homologs of major surface protease (gp63) genes in Trypanosoma rangeli
    Vector Borne Zoonotic Dis10, 847-853. PubMed  Europe PubMed DOI
34. Gomez,M.A. and Olivier,M.
    Proteases and phosphatases during Leishmania-macrophage interaction: paving the road for pathogenesis
    Virulence1, 314-318. PubMed  Europe PubMed DOI
35. Marcoux,V., Wei,G., Tabel,H. and Bull,H.J.
    Characterization of major surface protease homologues of Trypanosoma congolense
    J Biomed Biotechnol2010, 418157-418157. PubMed  Europe PubMed DOI
36. Mazumder,S., Ganguly,A. and Ali,N.
    The effect of C-terminal domain deletion on the catalytic activity of Leishmania donovani surface proteinase GP63: role of Ser446 in proteolysis
    Biochimie92, 1876-1885. PubMed  Europe PubMed DOI
37. Pereira,F.M., Santos-Mallet,J.R., Branquinha,M.H., D'Avila-Levy,C.M. and Santos,A.L.
    Influence of leishmanolysin-like molecules of Herpetomonas samuelpessoai on the interaction with macrophages
    Microbes Infect12, 1061-1070. PubMed  Europe PubMed DOI
38. Yao,C.
    Major surface protease of trypanosomatids: one size fits all?
    Infect Immun78, 22-31. PubMed  Europe PubMed DOI  V
2009
39. Gomez,M.A., Contreras,I., Halle,M., Tremblay,M.L., McMaster,R.W. and Olivier,M.
    Leishmania GP63 alters host signaling through cleavage-activated protein tyrosine phosphatases
    Sci Signal2, ra58-ra58. PubMed  Europe PubMed DOI
40. Halle,M., Gomez,M.A., Stuible,M., Shimizu,H., McMaster,W.R., Olivier,M. and Tremblay,M.L.
    The Leishmania surface protease GP63 cleaves multiple intracellular proteins and actively participates in p38 mitogen-activated protein kinase inactivation
    J Biol Chem284, 6893-6908. PubMed  Europe PubMed DOI
41. Helm,J.R., Wilson,M.E. and Donelson,J.E.
    Differential expression of a protease gene family in African trypanosomes
    Mol Biochem Parasitol163, 8-18. PubMed  Europe PubMed DOI
42. Matteoli,F.P., D'Avila-Levy,C.M., Santos,L.O., Barbosa,G.M., Holandino,C., Branquinha,M.H. and Santos,A.L.
    Roles of the endosymbiont and leishmanolysin-like molecules expressed by Crithidia deanei in the interaction with mammalian fibroblasts
    Exp Parasitol121, 246-253. PubMed  Europe PubMed DOI
2008
43. Hsiao,C.H., Yao,C., Storlie,P., Donelson,J.E. and Wilson,M.E.
    The major surface protease (MSP or GP63) in the intracellular amastigote stage of Leishmania chagasi
    Mol Biochem Parasitol157, 148-159. PubMed  Europe PubMed DOI
44. Kulkarni,M.M., Jones,E.A., McMaster,W.R. and McGwire,B.S.
    Fibronectin binding and proteolytic degradation by Leishmania and effects on macrophage activation
    Infect Immun76, 1738-1747. PubMed  Europe PubMed DOI
45. Tan,C.W., Jesudhasan,P. and Woo,P.T.
    Towards a metalloprotease-DNA vaccine against piscine cryptobiosis caused by Cryptobia salmositica
    Parasitol Res102, 265-275. PubMed  Europe PubMed DOI  T
2007
46. Grandgenett,P.M., Otsu,K., Wilson,H.R., Wilson,M.E. and Donelson,J.E.
    A function for a specific zinc metalloprotease of african trypanosomes
    PLoS Pathog3, 1432-1445. PubMed  Europe PubMed DOI
47. Mauricio,I.L., Gaunt,M.W., Stothard,J.R. and Miles,M.A.
    Glycoprotein 63 (gp63) genes show gene conversion and reveal the evolution of Old World Leishmania
    Int J Parasitol37, 565-576. PubMed  Europe PubMed DOI
2006
48. [YEAR:3-10-2006]Cuervo,P., Saboia-Vahia,L., Costa Silva-Filho,F., Fernandes,O., Cupolillo,E. and De Jesus,J.B.
    A zymographic study of metalloprotease activities in extracts and extracellular secretions of Leishmania (Viannia) braziliensis strains
    Parasitology132, 177-185. PubMed  Europe PubMed DOI
49. [YEAR:31-1-2006]Nogueira de Melo,A.C., D'Avila-Levy,C.M., Dias,F.A., Armada,J.L., Silva,H.D., Lopes,A.H., Santos,A.L., Branquinha,M.H. and Vermelho,A.B.
    Peptidases and gp63-like proteins in Herpetomonas megaseliae: possible involvement in the adhesion to the invertebrate host
    Int J Parasitol36, 415-422. PubMed  Europe PubMed DOI
50. Santos,A.L., Branquinha,M.H. and D'Avila-Levy,C.M.
    The ubiquitous gp63-like metalloprotease from lower trypanosomatids: in the search for a function
    An Acad Bras Cienc78, 687-714. PubMed  Europe PubMed
2005
51. [YEAR:9-4-2005]Purdy,J.E., Donelson,J.E. and Wilson,M.E.
    Regulation of genes encoding the major surface protease of Leishmania chagasi via mRNA stability
    Mol Biochem Parasitol142, 88-97. PubMed  Europe PubMed DOI
52. Yao,C., Luo,J., Hsiao,C., Donelson,J.E. and Wilson,M.E.
    Internal and surface subpopulations of the major surface protease (MSP) of Leishmania chagasi
    Mol Biochem Parasitol139, 173-183. PubMed  Europe PubMed DOI
2004
53. Bouvier,J.
    Leishmanolysin
    [ISSN:0-12-079610-4]2, 764-769.  V
54. Hajmova,M., Chang,K.P., Kolli,B. and Volf,P.
    Down-regulation of gp63 in Leishmania amazonensis reduces its early development in Lutzomyia longipalpis
    Microbes Infect6, 646-649. PubMed  Europe PubMed DOI
55. Yao,C., Luo,J., Storlie,P., Donelson,J.E. and Wilson,M.E.
    Multiple products of the Leishmania chagasi major surface protease (MSP or GP63) gene family
    Mol Biochem Parasitol135, 171-183. PubMed  Europe PubMed DOI
2003
56. Cuevas,I.C., Cazzulo,J.J. and Sanchez,D.O.
    gp63 homologues in Trypanosoma cruzi: surface antigens with metalloprotease activity and a possible role in host cell infection
    Infect Immun71, 5739-5749. PubMed  Europe PubMed DOI
57. [YEAR:4-7-2003]LaCount,D.J., Gruszynski,A.E., Grandgenett,P.M., Bangs,J.D. and Donelson,J.E.
    Expression and function of the Trypanosoma brucei major surface protease (GP63) genes
    J Biol Chem278, 24658-24664. PubMed  Europe PubMed DOI
58. McGwire,B.S., Chang,K.P. and Engman,D.M.
    Migration through the extracellular matrix by the parasitic protozoan Leishmania is enhanced by surface metalloprotease gp63
    Infect Immun71, 1008-1010. PubMed  Europe PubMed DOI
59. Yao,C., Donelson,J.E. and Wilson,M.E.
    The major surface protease (MSP or GP63) of Leishmania sp. Biosynthesis, regulation of expression, and function
    Mol Biochem Parasitol132, 1-16. PubMed  Europe PubMed DOI
2002
60. [YEAR:1-11-2002]Corradin,S., Ransijn,A., Corradin,G., Bouvier,J., Delgado,M.B., Fernandez-Carneado,J., Mottram,J.C., Vergeres,G. and Mauel,J.
    Novel peptide inhibitors of Leishmania gp63 based on the cleavage site of MARCKS (myristoylated alanine-rich C kinase substrate)-related protein
    Biochem J367, 761-769. PubMed  Europe PubMed DOI  I
61. Joshi,P.B., Kelly,B.L., Kamhawi,S., Sacks,D.L. and McMaster,W.R.
    Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor
    Mol Biochem Parasitol120, 33-40. PubMed  Europe PubMed
62. [YEAR:15-3-2002]McGwire,B.S., O'Connell,W.A., Chang,K.P. and Engman,D.M.
    Extracellular release of the glycosylphosphatidylinositol (GPI)-linked Leishmania surface metalloprotease, gp63, is independent of GPI phospholipolysis: implications for parasite virulence
    J Biol Chem277, 8802-8809. PubMed  Europe PubMed DOI
63. [YEAR:30-4-2002]Yao,C., Leidal,K.G., Brittingham,A., Tarr,D.E., Donelson,J.E. and Wilson,M.E.
    Biosynthesis of the major surface protease GP63 of Leishmania chagasi
    Mol Biochem Parasitol121, 119-128. PubMed  Europe PubMed DOI
2001
64. [YEAR:25-4-2001]Bangs,J.D., Ransom,D.A., Nimick,M., Christie,G. and Hooper,N.M.
    In vitro cytocidal effects on Trypanosoma brucei and inhibition of Leishmania major GP63 by peptidomimetic metalloprotease inhibitors
    Mol Biochem Parasitol114, 111-117. PubMed  Europe PubMed DOI  I
2000
65. Alvarez-Valin,F., Tort,J.F. and Bernardi,G.
    Nonrandom spatial distribution of synonymous substitutions in the GP63 gene from Leishmania
    Genetics155, 1683-1692. PubMed  Europe PubMed
1999
66. [YEAR:3-9-1999]Corradin,S., Ransijn,A., Corradin,G., Roggero,M.A., Schmitz,A.A., Schneider,P., Mauel,J. and Vergeres,G.
    MARCKS-related protein (MRP) is a substrate for the Leishmania major surface protease leishmanolysin (gp63)
    J Biol Chem274, 25411-25418. PubMed  Europe PubMed DOI
67. Puentes,F., Guzman,F., Marin,V., Alonso,C., Patarroyo,M.E. and Moreno,A.
    Leishmania: fine mapping of the leishmanolysin molecule's conserved core domains involved in binding and internalization
    Exp Parasitol93, 7-22. PubMed  Europe PubMed DOI
68. [YEAR:17-3-1999]Spitzer,N., Jardim,A., Lippert,D. and Olafson,R.W.
    Long-term protection of mice against Leishmania major with a synthetic peptide vaccine
    Vaccine17, 1298-1300. PubMed  Europe PubMed DOI
1998
69. [YEAR:15-8-1998]Schlagenhauf,E., Etges,R. and Metcalf,P.
    The crystal structure of the Leishmania major surface proteinase leishmanolysin (gp63)
    Structure6, 1035-1046. PubMed  Europe PubMed  S
70. [YEAR:15-5-1998]Voth,B.R., Kelly,B.L., Joshi,P.B., Ivens,A.C. and McMaster,W.R.
    Differentially expressed Leishmania major gp63 genes encode cell surface leishmanolysin with distinct signals for glycosylphosphatidylinositol attachment
    Mol Biochem Parasitol93, 31-41. PubMed  Europe PubMed DOI
1997
71. Bangs,J.D., Ransom,D.M., McDowell,M.A. and Brouch,E.M.
    Expression of bloodstream variant surface glycoproteins in procyclic stage Trypanosoma brucei: role of GPI anchors in secretion
    EMBO J16, 4285-4294. PubMed  Europe PubMed DOI
72. El-Sayed,N.M. and Donelson,J.E.
    African trypanosomes have differentially expressed genes encoding homologues of the Leishmania GP63 surface protease
    J Biol Chem272, 26742-26748. PubMed  Europe PubMed DOI
73. Garcia,M.R., Graham,S., Harris,R.A., Beverley,S.M. and Kaye,P.M.
    Epitope cleavage by Leishmania endopeptidase(s) limits the efficiency of the exogenous pathway of major histocompatibility complex class I-associated antigen presentation
    Eur J Immunol27, 1005-1013. PubMed  Europe PubMed DOI
74. Gonzalez-Aseguinolaza,G., Almazan,F., Rodriguez,J.F., Marquet,A. and Larraga,V.
    Cloning of the gp63 surface protease of Leishmania infantum. Differential post-translational modifications correlated with different infective forms
    Biochim Biophys Acta1361, 92-102. PubMed  Europe PubMed DOI
75. Morrison,C.J., McMaster,W.R. and Piret,J.M.
    Differential stability of proteolytically active and inactive recombinant metalloproteinase in chinese hamster ovary cells
    Biotechnol Bioeng53, 594-600. PubMed  Europe PubMed DOI
1996
76. McGwire,B.S. and Chang,K.P.
    Posttranslational regulation of a Leishmania HEXXH metalloprotease (gp63). The effects of site-specific mutagenesis of catalytic, zinc binding, N-glycosylation, and glycosyl phosphatidylinositol addition sites on N-terminal end cleavage, intracellular stability, and extracellular exit
    J Biol Chem271, 7903-7909. PubMed  Europe PubMed
77. Seay,M.B., Heard,P.L. and Chaudhuri,G.
    Surface Zn-proteinase as a molecule for defense of Leishmania mexicana amazonensis promastigotes against cytolysis inside macrophage phagolysosomes
    Infect Immun64, 5129-5137. PubMed  Europe PubMed
1995
78. Bouvier,J., Schneider,P. and Etges,R.
    Leishmanolysin: surface metalloproteinase of Leishmania
    Methods Enzymol248, 614-633. PubMed  Europe PubMed DOI  V
79. Brittingham,A., Morrison,C.J., McMaster,W.R., McGwire,B.S., Chang,K.P. and Mosser,D.M.
    Role of the Leishmania surface protease gp63 in complement fixation, cell adhesion, and resistance to complement-mediated lysis
    J Immunol155, 3102-3111. PubMed  Europe PubMed
80. Macdonald,M.H., Morrison,C.J. and McMaster,W.R.
    Analysis of the active site and activation mechanism of the Leishmania surface metalloproteinase GP63
    Biochim Biophys Acta1253, 199-207. PubMed  Europe PubMed DOI
81. [YEAR:19-5-1995]Ramamoorthy,R., Swihart,K.G., McCoy,J.J., Wilson,M.E. and Donelson,J.E.
    Intergenic regions between tandem gp63 genes influence the differential expression of gp63 RNAs in Leishmania chagasi promastigotes
    J Biol Chem270, 12133-12139. PubMed  Europe PubMed DOI
82. Xu,D. and Liew,F.Y.
    Protection against leishmaniasis by injection of DNA encoding a major surface glycoprotein, gp63, of L. major
    Immunology84, 173-176. PubMed  Europe PubMed
1994
83. Funk,V.A., Jardim,A. and Olafson,R.W.
    An investigation into the significance of the N-linked oligosaccharides of Leishmania gp63
    Mol Biochem Parasitol63, 23-35. PubMed  Europe PubMed DOI
84. Hey,A.S., Theander,T.G., Hviid,L., Hazrati,S.M., Kemp,M. and Kharazmi,A.
    The major surface glycoprotein (gp63) from Leishmania major and Leishmania donovani cleaves CD4 molecules on human T cells
    J Immunol152, 4542-4548. PubMed  Europe PubMed
85. Kemp,M., Hey,A.S., Bendtzen,K., Kharazmi,A. and Theander,T.G.
    Th1-like human T-cell clones recognizing Leishmania gp63 inhibit Leishmania major in human macrophages
    Scand J Immunol40, 629-635. PubMed  Europe PubMed DOI
1993
86. [YEAR:30-11-1993]Button,L.L., Wilson,G., Astell,C.R. and McMaster,W.R.
    Recombinant Leishmania surface glycoprotein GP63 is secreted in the baculovirus expression system as a latent metalloproteinase
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87. Inverso,J.A., Medina-Acosta,E., O'Connor,J., Russell,D.G. and Cross,G.A.
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