Literature for peptidase M04.007: coccolysin

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

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    2026
  1. Ramchunder,K., Anderson,M.H. and Senzani,S.<br>Bacterial zinc metalloproteases as facilitators of pathogenic success: a review<br>Arch Microbiol (2026) 208, 97-97. PubMed  Europe PubMed DOI
  2. 2024
  3. Sheriff,E.K., Salvato,F., Andersen,S.E., Chatterjee,A., Kleiner,M. and Duerkop,B.A.<br>Enterococcal quorum-controlled protease alters phage infection<br>FEMS Microbes (2024) 5, xtae022-xtae022. PubMed  Europe PubMed DOI  PMC  EPMC
  4. 2022
  5. Willett,J.L.E., Robertson,E.B. and Dunny,G.M.<br>The Phosphatase Bph and Peptidyl-Prolyl Isomerase PrsA Are Required for Gelatinase Expression and Activity in Enterococcus faecalis<br>J Bacteriol (2022) 204, e0012922-e0012922. PubMed  Europe PubMed DOI  PMC  EPMC
  6. 2020
  7. LeValley,S.L., Tomaro-Duchesneau,C. and Britton,R.A.<br>Degradation of the incretin hormone glucagon-like peptide-1 (GLP-1) by Enterococcus faecalis metalloprotease GelE<br>mSphere (2020) 5 PubMed  Europe PubMed DOI
  8. 2019
  9. Brown,A.O., Graham,C.E., Cruz,M.R., Singh,K.V., Murray,B.E., Lorenz,M.C. and Garsin,D.A.<br>Antifungal activity of the Enterococcus faecalis peptide EntV requires protease cleavage and disulfide bond formation<br>MBio (2019) 10 PubMed  Europe PubMed DOI  PMC  EPMC
  10. 2018
  11. Rodriguez-Serrano,G.M., Garcia-Garibay,M., Cruz-Guerrero,A.E., Gomez-Ruiz,L., Ayala-Nino,A., Castaneda-Ovando,A. and Gonzalez-Olivares,L.G.<br>Proteolytic system of Streptococcus thermophilus<br>J Microbiol Biotechnol (2018) 28, 1581-1588. PubMed  Europe PubMed DOI  V
  12. 2017
  13. Stinemetz,E.K., Gao,P., Pinkston,K.L., Montealegre,M.C., Murray,B.E. and Harvey,B.R.<br>Processing of the major autolysin of E. faecalis, AtlA, by the zinc-metalloprotease, GelE, impacts AtlA septal localization and cell separation<br>PLoS ONE (2017) 12, e0186706-e0186706. PubMed  Europe PubMed DOI
  14. 2015
  15. Dundar,H., Brede,D.A., La Rosa,S.L., El-Gendy,A.O., Diep,D.B. and Nes,I.F.<br>The fsr quorum-sensing system and cognate gelatinase orchestrate the expression and processing of proprotein EF_1097 into the mature antimicrobial peptide enterocin O16<br>J Bacteriol (2015) 197, 2112-2121. PubMed  Europe PubMed DOI
  16. Maharshak,N., Huh,E.Y., Paiboonrungruang,C., Shanahan,M., Thurlow,L., Herzog,J., Djukic,Z., Orlando,R., Pawlinski,R., Ellermann,M., Borst,L., Patel,S., Dotan,I., Sartor,R.B. and Carroll,I.M.<br>Enterococcus faecalis gelatinase mediates intestinal permeability via protease-activated receptor 2<br>Infect Immun (2015) 83, 2762-2770. PubMed  Europe PubMed DOI
  17. 2012
  18. Makinen,K.K.<br>Coccolysin<br>[ISSN:978-0-12-407744-7] (2012) 3, 574-577. DOI
  19. 2011
  20. Steck,N., Hoffmann,M., Sava,I.G., Kim,S.C., Hahne,H., Tonkonogy,S.L., Mair,K., Krueger,D., Pruteanu,M., Shanahan,F., Vogelmann,R., Schemann,M., Kuster,B., Sartor,R.B. and Haller,D.<br>Enterococcus faecalis metalloprotease compromises epithelial barrier and contributes to intestinal inflammation<br>Gastroenterology (2011) 141, 959-971. PubMed  Europe PubMed DOI
  21. Vedantam,G. and Viswanathan,V.K.<br>Unlocking the gates to inflammatory bowel disease: the role of Enterococcus faecalis gelatinase<br>Gastroenterology (2011) 141, 795-798. PubMed  Europe PubMed DOI
  22. 2009
  23. Nishiguchi,K., Nagata,K., Tanokura,M., Sonomoto,K. and Nakayama,J.<br>Structure-activity relationship of gelatinase biosynthesis-activating pheromone of Enterococcus faecalis<br>J Bacteriol (2009) 191, 641-650. PubMed  Europe PubMed DOI  PMC  EPMC
  24. 2008
  25. Park,S.Y., Shin,Y.P., Kim,C.H., Park,H.J., Seong,Y.S., Kim,B.S., Seo,S.J. and Lee,I.H.<br>Immune evasion of Enterococcus faecalis by an extracellular gelatinase that cleaves C3 and iC3b<br>J Immunol (2008) 181, 6328-6336. PubMed  Europe PubMed
  26. 2007
  27. Del Papa,M.F., Hancock,L.E., Thomas,V.C. and Perego,M.<br>Full activation of Enterococcus faecalis gelatinase by a C-terminal proteolytic cleavage<br>J Bacteriol (2007) 189, 8835-8843. PubMed  Europe PubMed DOI  PMC  EPMC
  28. Nakayama,J., Tanaka,E., Kariyama,R., Nagata,K., Nishiguchi,K., Mitsuhata,R., Uemura,Y., Tanokura,M., Kumon,H. and Sonomoto,K.<br>Siamycin attenuates fsr quorum sensing mediated by a gelatinase biosynthesis-activating pheromone in Enterococcus faecalis<br>J Bacteriol (2007) 189, 1358-1365. PubMed  Europe PubMed DOI  PMC  EPMC
  29. Park,S.Y., Kim,K.M., Lee,J.H., Seo,S.J. and Lee,I.H.<br>Extracellular gelatinase of Enterococcus faecalis destroys a defense system in insect hemolymph and human serum<br>Infect Immun (2007) 75, 1861-1869. PubMed  Europe PubMed DOI  PMC  EPMC
  30. 2005
  31. Zeng,J., Teng,F. and Murray,B.E.<br>Gelatinase is important for translocation of Enterococcus faecalis across polarized human enterocyte-like T84 cells<br>Infect Immun (2005) 73, 1606-1612. PubMed  Europe PubMed DOI  PMC  EPMC
  32. 2004
  33. Hancock,L.E. and Perego,M.<br>The Enterococcus faecalis fsr two-component system controls biofilm development through production of gelatinase<br>J Bacteriol (2004) 186, 5629-5639. PubMed  Europe PubMed DOI  PMC  EPMC
  34. Makinen,K.K. and Makinen,P.L.<br>Coccolysin<br>[ISSN:0-12-079610-4] (2004) 2, 396-398.  V
  35. 2003
  36. Waters,C.M., Antiporta,M.H., Murray,B.E. and Dunny,G.M.<br>Role of the Enterococcus faecalis GelE protease in determination of cellular chain length, supernatant pheromone levels, and degradation of fibrin and misfolded surface proteins<br>J Bacteriol (2003) 185, 3613-3623. PubMed  Europe PubMed DOI  PMC  EPMC
  37. 2002
  38. Sifri,C.D., Mylonakis,E., Singh,K.V., Qin,X., Garsin,D.A., Murray,B.E., Ausubel,F.M. and Calderwood,S.B.<br>Virulence effect of Enterococcus faecalis protease genes and the quorum-sensing locus fsr in Caenorhabditis elegans and mice<br>Infect Immun (2002) 70, 5647-5650. PubMed  Europe PubMed DOI  PMC  EPMC
  39. 2001
  40. Kanemitsu,K., Nishino,T., Kunishima,H., Okamura,N., Takemura,H., Yamamoto,H. and Kaku,M.<br>Quantitative determination of gelatinase activity among enterococci<br>J Microbiol Methods (2001) 47, 11-16. PubMed  Europe PubMed DOI
  41. Nakayama,J., Cao,Y., Horii,T., Sakuda,S., Akkermans,A.D., de Vos,W.M. and Nagasawa,H.<br>Gelatinase biosynthesis-activating pheromone: a peptide lactone that mediates a quorum sensing in Enterococcus faecalis<br>Mol Microbiol (2001) 41, 145-154. PubMed  Europe PubMed DOI
  42. Qin,X., Singh,K.V., Weinstock,G.M. and Murray,B.E.<br>Characterization of fsr, a regulator controlling expression of gelatinase and serine protease in Enterococcus faecalis OG1RF<br>J Bacteriol (2001) 183, 3372-3382. PubMed  Europe PubMed DOI  PMC  EPMC
  43. 2000
  44. Qin,X., Singh,K.V., Weinstock,G.M. and Murray,B.E.<br>Effects of Enterococcus faecalis fsr genes on production of gelatinase and a serine protease and virulence<br>Infect Immun (2000) 68, 2579-2586. PubMed  Europe PubMed DOI  PMC  EPMC
  45. 1994
  46. Makinen,P.L. and Makinen,K.K.<br>The Enterococcus faecalis extracellular metalloendopeptidase (EC 3.4.24.30; coccolysin) inactivates human endothelin at bonds involving hydrophobic amino acid residues<br>Biochem Biophys Res Commun (1994) 200, 981-985. PubMed  Europe PubMed DOI
  47. 1991
  48. Su,Y.A., Sulavik,M.C., He,P., Makinen,K.K., Makinen,P.L., Fiedler,S., Wirth,R. and Clewell,D.B.<br>Nucleotide sequence of the gelatinase gene (gelE) from Enterococcus faecalis subsp. liquefaciens<br>Infect Immun (1991) 59, 415-420. PubMed  Europe PubMed  PMC  EPMC
  49. 1989
  50. Makinen,P.L., Clewell,D.B., An,F. and Makinen,K.K.<br>Purification and substrate specificity of a strongly hydrophobic extracellular metalloendopeptidase ("gelatinase") from Streptococcus faecalis (strain 0G1-10)<br>J Biol Chem (1989) 264, 3325-3334. PubMed  Europe PubMed
  51. 1980
  52. Smith,R.A., Green,J. and Kopper,P.H.<br>The purification and properties of a fibrinolytic neutral metalloendopeptidase from Streptococcus faecalis<br>Arch Biochem Biophys (1980) 202, 629-638. PubMed  Europe PubMed
  53. 1974
  54. Desmazeaud,M.J.<br>[General properties and specificity of action of a neutral intracellular endopeptidase from Streptococcus thermophilus]<br>Biochimie (1974) 56, 1173-1181. PubMed  Europe PubMed
  55. 1964
  56. Bleiweis,A.S. and Zimmerman,L.N.<br>Properties of proteinase from Streptococcus faecalis var. liquefaciens<br>J Bacteriol (1964) 88, 653-659. PubMed  Europe PubMed
  57. 1955
  58. Grutter,F.H. and Zimmerman,L.N.<br>A proteolytic enzyme of Streptococcus zymogenes<br>J Bacteriol (1955) 69, 728-732. PubMed  Europe PubMed