Literature for peptidase G06.001: Ras/Rap1-specific peptidase

(Topics flags: S Structure, K Knockout, P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Escher,T.E., Yuk,S.A., Qian,Y., Qiang,W., Almunif,S., Sharma,S., Scott,E.A. and Satchell,K.J.F.
   Expression of a RAS Degrader via Synthetic Nanocarrier-Mediated mRNA Delivery Reduces Pancreatic Tumors
   ACS Appl Bio Mater (2025) PubMed  Europe PubMed DOI
2024
2. Escher,T.E., Yuk,S.A., Qian,Y., Stubbs,C.K., Scott,E.A. and Satchell,K.J.F.
   Therapeutic expression of RAS Degrader RRSP in Pancreatic Cancer via Nanocarrier-mediated mRNA delivery
   bioRxiv (2024) PubMed  Europe PubMed DOI  PMC  EPMC
2023
3. Escher,T.E. and Satchell,K.J.F.
   RAS degraders: The new frontier for RAS-driven cancers
   Mol Ther (2023) 31, 1904-1919. PubMed  Europe PubMed DOI  V
2021
4. Stubbs,C.K., Biancucci,M., Vidimar,V. and Satchell,K.J.F.
   RAS specific protease induces irreversible growth arrest via p27 in several KRAS mutant colorectal cancer cell lines
   Sci Rep (2021) 11, 17925-17925. PubMed  Europe PubMed DOI  PMC  EPMC
2020
5. Loftis,A.R., Santos,M.S., Truex,N.L., Biancucci,M., Satchell,K.J.F. and Pentelute,B.L.
   Anthrax protective antigen retargeted with single-chain variable fragments delivers enzymes to pancreatic cancer cells
   Chembiochem (2020) PubMed  Europe PubMed DOI
6. Vidimar,V., Beilhartz,G.L., Park,M., Biancucci,M., Kieffer,M.B., Gius,D.R., Melnyk,R.A. and Satchell,K.J.F.
   An engineered chimeric toxin that cleaves activated mutant and wild-type RAS inhibits tumor growth
   Proc Natl Acad Sci U S A (2020) 117, 16938-16948. PubMed  Europe PubMed DOI  PMC  EPMC
2018
7. Biancucci,M., Minasov,G., Banerjee,A., Herrera,A., Woida,P.J., Kieffer,M.B., Bindu,L., Abreu-Blanco,M., Anderson,W.F., Gaponenko,V., Stephen,A.G., Holderfield,M. and Satchell,K.J.F.
   The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling
   Sci Signal (2018) 11 PubMed  Europe PubMed DOI  S
8. Jang,S.Y., Hwang,J., Kim,B.S., Lee,E.Y., Oh,B.H. and Kim,M.H.
   Structural basis of inactivation of Ras and Rap1 small GTPases by Ras/Rap1-specific endopeptidase from the sepsis-causing pathogen Vibrio vulnificus
   J Biol Chem (2018) 293, 18110-18122. PubMed  Europe PubMed DOI  S
2017
9. Biancucci,M., Rabideau,A.E., Lu,Z., Loftis,A.R., Pentelute,B.L. and Satchell,K.J.F.
   Substrate recognition of MARTX Ras/Rap1-specific endopeptidase
   Biochemistry (2017) 56, 2747-2757. PubMed  Europe PubMed DOI  P
10. Hisao,G.S., Brothers,M.C., Ho,M., Wilson,B.A. and Rienstra,C.M.
    The membrane localization domains of two distinct bacterial toxins form a 4-helix-bundle in solution
    Protein Sci (2017) 26, 497-504. PubMed  Europe PubMed DOI  S
11. Kweon,S.M., Zhu,B., Chen,Y., Aravind,L., Xu,S.Y. and Feldman,D.E.
    Erasure of Tet-oxidized 5-methylcytosine by a SRAP nuclease
    Cell Rep (2017) 21, 482-494. PubMed  Europe PubMed DOI  K
2015
12. Antic,I., Biancucci,M., Zhu,Y., Gius,D.R. and Satchell,K.J.
    Site-specific processing of Ras and Rap1 switch I by a MARTX toxin effector domain
    Nat Commun (2015) 6, 7396-7396. PubMed  Europe PubMed DOI
13. Biancucci,M. and Satchell,K.J.
    A bacterial toxin that cleaves Ras oncoprotein
    Oncotarget (2015) 6, 18742-18743. PubMed  Europe PubMed DOI
2014
14. Antic,I., Biancucci,M. and Satchell,K.J.
    Cytotoxicity of the Vibrio vulnificus MARTX toxin effector DUF5 is linked to the C2A subdomain
    Proteins (2014) 82, 2643-2656. PubMed  Europe PubMed DOI  PMC  EPMC
2011
15. Kwak,J.S., Jeong,H.G. and Satchell,K.J.
    Vibrio vulnificus rtxA1 gene recombination generates toxin variants with altered potency during intestinal infection
    Proc Natl Acad Sci U S A (2011) 108, 1645-1650. PubMed  Europe PubMed DOI  PMC  EPMC
2007
16. Satchell,K.J.
    MARTX, multifunctional autoprocessing repeats-in-toxin toxins
    Infect Immun (2007) 75, 5079-5084. PubMed  Europe PubMed DOI  PMC  EPMC  V