Literature for peptidase C97.002: desumoylating isopeptidase 2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature

(Topics flags: T Target, K Knockout, E Expression, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

2019

Ou,X., Zhang,G.T., Xu,Z., Chen,J.S., Xie,Y., Liu,J.K. and Liu,X.P. Desumoylating isopeptidase 2 (DESI2) inhibits proliferation and promotes apoptosis of pancreatic cancer cells through regulating PI3K/AKT/mTOR signaling pathway Pathol Oncol Res (2019) 25, 635-646. PubMed Europe PubMed DOI
Xie,X., Wang,X., Liao,W., Fei,R., Wu,N., Cong,X., Chen,Q., Wei,L., Wang,Y. and Chen,H. PPPDE1 promotes hepatocellular carcinoma development by negatively regulate p53 and apoptosis Apoptosis (2019) 24, 135-144. PubMed Europe PubMed DOI T

2017

Xie,X., Wang,X., Jiang,D., Wang,J., Fei,R., Cong,X., Wei,L., Wang,Y. and Chen,H. PPPDE1 is a novel deubiquitinase belonging to a cysteine isopeptidase family Biochem Biophys Res Commun (2017) 488, 291-296. PubMed Europe PubMed DOI

2014

Kang,Y.H., Shen,C.C., Yao,Y.Q., Yu,L., Cui,X.Y., He,Y., Yang,J.L. and Gou,L.T. Implications of PPPDE1 expression in the distribution of plakoglobin and beta-catenin in pancreatic ductal adenocarcinoma Oncol Lett (2014) 8, 1229-1233. PubMed Europe PubMed DOI PMC EPMC

2013

Li,L., Chen,D.B., Lin,C., Cao,K., Wan,Y., Zhao,X.Y., Nie,C.L., Yuan,Z. and Wei,Y.Q. hPNAS-4 inhibits proliferation through S phase arrest and apoptosis: underlying action mechanism in ovarian cancer cells Apoptosis (2013) 18, 467-479. PubMed Europe PubMed DOI

2012

Cai,P., Xia,X., Li,F., Cui,Y., Yang,Q. and Chen,M. PNAS4 knockout does not induce obviously neurocytes apoptosis and abnormal development in mice brain Mol Biol Rep (2012) 39, 621-628. PubMed Europe PubMed DOI K
Cao,K., Lin,C., Dai,Q., Li,L., Lei,T.J., Xie,Y., Tang,M.H. and Yuan,Z. [Cloning, expression and purification of human PNAS-4] Sichuan Da Xue Xue Bao Yi Xue Ban (2012) 43, 503-506. PubMed Europe PubMed
Zeng,H., Yuan,Z., Zhu,H., Li,L., Shi,H., Wang,Z., Fan,Y., Deng,Q., Zeng,J., He,Y., Xiao,J. and Li,Z. Expression of hPNAS-4 radiosensitizes Lewis lung cancer Int J Radiat Oncol Biol Phys (2012) 84, e533-e540. PubMed Europe PubMed DOI

2011

Qi,X., Song,X., Liu,P., Yi,T., Li,S., Xie,C., Zheng,Y., Bai,Y., Sun,C., Wei,Y. and Zhao,X. Antitumor effects of PLGA nanoparticles encapsulating the human PNAS-4 gene combined with cisplatin in ovarian cancer Oncol Rep (2011) 26, 703-710. PubMed Europe PubMed DOI U

2010

Deng,H., Jiang,Q., Liang,S., Yan,F., Hou,S., Qian,Z., Li,J., Wen,Y., Yang,J. and Wei,Y. Prokaryotic expression, purification and characterization of a novel pro-apoptosis protein hPNAS-4 Biotechnol Appl Biochem (2010) 55, 63-72. PubMed Europe PubMed DOI E
Yan,F., Ruan,X.Z., Yang,H.S., Yao,S.H., Zhao,X.Y., Gou,L.T., Ma,F.X., Yuan,Z., Deng,H.X. and Wei,Y.Q. Identification, characterization, and effects of Xenopus laevis PNAS-4 gene on embryonic development J Biomed Biotechnol (2010) 2010, 134764-134764. PubMed Europe PubMed DOI PMC EPMC

2009

Gou,L.T., Tong,A.P., Yan,F., Yuan,Z., He,F., Wang,W., Zhou,Y., Chen,L.J., Tang,M.H. and Yang,J.L. Altered protein-expressing profile in hPNAS4-induced apoptosis in A549 human lung adenocarcinoma cells J Cell Biochem (2009) 108, 1211-1219. PubMed Europe PubMed DOI
Hou,S., Zhao,Z., Yan,F., Chen,X., Deng,H., Chen,X., Wang,Y. and Wei,Y. Genetic transfer of PNAS-4 induces apoptosis and enhances sensitivity to gemcitabine in lung cancer Cell Biol Int (2009) 33, 276-282. PubMed Europe PubMed DOI U
Yan,F., Gou,L., Yang,J., Chen,L., Tong,A., Tang,M., Yuan,Z., Yao,S., Zhang,P. and Wei,Y. A novel pro-apoptosis gene PNAS4 that induces apoptosis in A549 human lung adenocarcinoma cells and inhibits tumor growth in mice Biochimie (2009) 91, 502-507. PubMed Europe PubMed DOI
Yuan,Z., Yan,F., Wang,Y.S., Liu,H.Y., Gou,L.T., Zhao,X.Y., Lai,S.T., Deng,H.X., Li,J., Ding,Z.Y., Xiong,S.Q., Kan,B., Mao,Y.Q., Chen,L.J., Wei,Y.Q. and Zhao,X. PNAS-4, a novel pro-apoptotic gene, can potentiate antineoplastic effects of cisplatin Cancer Chemother Pharmacol (2009) 65, 13-25. PubMed Europe PubMed DOI
Yuan,Z., Liu,H., Yan,F., Wang,Y., Gou,L., Nie,C., Ding,Z., Lai,S., Zhao,Y., Zhao,X., Li,J., Deng,H., Mao,Y., Chen,L., Wei,Y. and Zhao,X. Improved therapeutic efficacy against murine carcinoma by combining honokiol with gene therapy of PNAS-4, a novel pro-apoptotic gene Cancer Sci (2009) 100, 1757-1766. PubMed Europe PubMed DOI U

2008

Mo,D., Zhu,Z., te Pas,M.F., Li,X., Yang,S., Wang,H., Wang,H. and Li,K. Characterization, expression profiles, intracellular distribution and association analysis of porcine PNAS-4 gene with production traits BMC Genet (2008) 9, 40-40. PubMed Europe PubMed DOI PMC EPMC
Yao,S., Xie,L., Qian,M., Yang,H., Zhou,L., Zhou,Q., Yan,F., Gou,L., Wei,Y., Zhao,X. and Mo,X. Pnas4 is a novel regulator for convergence and extension during vertebrate gastrulation FEBS Lett (2008) 582, 2325-2332. PubMed Europe PubMed DOI
Zhang,P., Wang,C.T., Yan,F., Gou,L., Tong,A.P., Cai,F., Li,Q., Deng,H.X. and Wei,Y.Q. Prokaryotic expression of a novel mouse pro-apoptosis protein PNAS-4 and application of its polyclonal antibodies Braz J Med Biol Res (2008) 41, 504-511. PubMed Europe PubMed

2007

Yan,F., Qian,M., Yang,F., Cai,F., Yuan,Z., Lai,S., Zhao,X., Gou,L., Hu,Z. and Deng,H. A novel pro-apoptosis protein PNAS-4 from Xenopus laevis: cloning, expression, purification, and polyclonal antibody production Biochemistry (Mosc) (2007) 72, 664-671. PubMed Europe PubMed