Literature for peptidase C97.002: desumoylating isopeptidase 2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature

(Topics flags: T Target, K Knockout, E Expression, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2019
  1. Ou,X., Zhang,G.T., Xu,Z., Chen,J.S., Xie,Y., Liu,J.K. and Liu,X.P.
    Desumoylating isopeptidase 2 (DESI2) inhibits proliferation and promotes apoptosis of pancreatic cancer cells through regulating PI3K/AKT/mTOR signaling pathway
    Pathol Oncol Res25, 635-646. PubMed  Europe PubMed DOI
  2. Xie,X., Wang,X., Liao,W., Fei,R., Wu,N., Cong,X., Chen,Q., Wei,L., Wang,Y. and Chen,H.
    PPPDE1 promotes hepatocellular carcinoma development by negatively regulate p53 and apoptosis
    Apoptosis24, 135-144. PubMed  Europe PubMed DOI  T
  3. 2017
  4. Xie,X., Wang,X., Jiang,D., Wang,J., Fei,R., Cong,X., Wei,L., Wang,Y. and Chen,H.
    PPPDE1 is a novel deubiquitinase belonging to a cysteine isopeptidase family
    Biochem Biophys Res Commun488, 291-296. PubMed  Europe PubMed DOI
  5. 2014
  6. Kang,Y.H., Shen,C.C., Yao,Y.Q., Yu,L., Cui,X.Y., He,Y., Yang,J.L. and Gou,L.T.
    Implications of PPPDE1 expression in the distribution of plakoglobin and beta-catenin in pancreatic ductal adenocarcinoma
    Oncol Lett8, 1229-1233. PubMed  Europe PubMed DOI
  7. 2013
  8. Li,L., Chen,D.B., Lin,C., Cao,K., Wan,Y., Zhao,X.Y., Nie,C.L., Yuan,Z. and Wei,Y.Q.
    hPNAS-4 inhibits proliferation through S phase arrest and apoptosis: underlying action mechanism in ovarian cancer cells
    Apoptosis18, 467-479. PubMed  Europe PubMed DOI
  9. 2012
  10. Cai,P., Xia,X., Li,F., Cui,Y., Yang,Q. and Chen,M.
    PNAS4 knockout does not induce obviously neurocytes apoptosis and abnormal development in mice brain
    Mol Biol Rep39, 621-628. PubMed  Europe PubMed DOI  K
  11. Cao,K., Lin,C., Dai,Q., Li,L., Lei,T.J., Xie,Y., Tang,M.H. and Yuan,Z.
    [Cloning, expression and purification of human PNAS-4]
    Sichuan Da Xue Xue Bao Yi Xue Ban43, 503-506. PubMed  Europe PubMed
  12. Zeng,H., Yuan,Z., Zhu,H., Li,L., Shi,H., Wang,Z., Fan,Y., Deng,Q., Zeng,J., He,Y., Xiao,J. and Li,Z.
    Expression of hPNAS-4 radiosensitizes Lewis lung cancer
    Int J Radiat Oncol Biol Phys84, e533-e540. PubMed  Europe PubMed DOI
  13. 2011
  14. Qi,X., Song,X., Liu,P., Yi,T., Li,S., Xie,C., Zheng,Y., Bai,Y., Sun,C., Wei,Y. and Zhao,X.
    Antitumor effects of PLGA nanoparticles encapsulating the human PNAS-4 gene combined with cisplatin in ovarian cancer
    Oncol Rep26, 703-710. PubMed  Europe PubMed DOI  U
  15. 2010
  16. Deng,H., Jiang,Q., Liang,S., Yan,F., Hou,S., Qian,Z., Li,J., Wen,Y., Yang,J. and Wei,Y.
    Prokaryotic expression, purification and characterization of a novel pro-apoptosis protein hPNAS-4
    Biotechnol Appl Biochem55, 63-72. PubMed  Europe PubMed DOI  E
  17. Yan,F., Ruan,X.Z., Yang,H.S., Yao,S.H., Zhao,X.Y., Gou,L.T., Ma,F.X., Yuan,Z., Deng,H.X. and Wei,Y.Q.
    Identification, characterization, and effects of Xenopus laevis PNAS-4 gene on embryonic development
    J Biomed Biotechnol2010, 134764-134764. PubMed  Europe PubMed DOI
  18. 2009
  19. Gou,L.T., Tong,A.P., Yan,F., Yuan,Z., He,F., Wang,W., Zhou,Y., Chen,L.J., Tang,M.H. and Yang,J.L.
    Altered protein-expressing profile in hPNAS4-induced apoptosis in A549 human lung adenocarcinoma cells
    J Cell Biochem108, 1211-1219. PubMed  Europe PubMed DOI
  20. Hou,S., Zhao,Z., Yan,F., Chen,X., Deng,H., Chen,X., Wang,Y. and Wei,Y.
    Genetic transfer of PNAS-4 induces apoptosis and enhances sensitivity to gemcitabine in lung cancer
    Cell Biol Int33, 276-282. PubMed  Europe PubMed DOI  U
  21. Yan,F., Gou,L., Yang,J., Chen,L., Tong,A., Tang,M., Yuan,Z., Yao,S., Zhang,P. and Wei,Y.
    A novel pro-apoptosis gene PNAS4 that induces apoptosis in A549 human lung adenocarcinoma cells and inhibits tumor growth in mice
    Biochimie91, 502-507. PubMed  Europe PubMed DOI
  22. Yuan,Z., Liu,H., Yan,F., Wang,Y., Gou,L., Nie,C., Ding,Z., Lai,S., Zhao,Y., Zhao,X., Li,J., Deng,H., Mao,Y., Chen,L., Wei,Y. and Zhao,X.
    Improved therapeutic efficacy against murine carcinoma by combining honokiol with gene therapy of PNAS-4, a novel pro-apoptotic gene
    Cancer Sci100, 1757-1766. PubMed  Europe PubMed DOI  U
  23. Yuan,Z., Yan,F., Wang,Y.S., Liu,H.Y., Gou,L.T., Zhao,X.Y., Lai,S.T., Deng,H.X., Li,J., Ding,Z.Y., Xiong,S.Q., Kan,B., Mao,Y.Q., Chen,L.J., Wei,Y.Q. and Zhao,X.
    PNAS-4, a novel pro-apoptotic gene, can potentiate antineoplastic effects of cisplatin
    Cancer Chemother Pharmacol65, 13-25. PubMed  Europe PubMed DOI
  24. 2008
  25. Mo,D., Zhu,Z., te Pas,M.F., Li,X., Yang,S., Wang,H., Wang,H. and Li,K.
    Characterization, expression profiles, intracellular distribution and association analysis of porcine PNAS-4 gene with production traits
    BMC Genet9, 40-40. PubMed  Europe PubMed DOI
  26. Yao,S., Xie,L., Qian,M., Yang,H., Zhou,L., Zhou,Q., Yan,F., Gou,L., Wei,Y., Zhao,X. and Mo,X.
    Pnas4 is a novel regulator for convergence and extension during vertebrate gastrulation
    FEBS Lett582, 2325-2332. PubMed  Europe PubMed DOI
  27. Zhang,P., Wang,C.T., Yan,F., Gou,L., Tong,A.P., Cai,F., Li,Q., Deng,H.X. and Wei,Y.Q.
    Prokaryotic expression of a novel mouse pro-apoptosis protein PNAS-4 and application of its polyclonal antibodies
    Braz J Med Biol Res41, 504-511. PubMed  Europe PubMed
  28. 2007
  29. Yan,F., Qian,M., Yang,F., Cai,F., Yuan,Z., Lai,S., Zhao,X., Gou,L., Hu,Z. and Deng,H.
    A novel pro-apoptosis protein PNAS-4 from Xenopus laevis: cloning, expression, purification, and polyclonal antibody production
    Biochemistry (Mosc)72, 664-671. PubMed  Europe PubMed