Literature for peptidase C87.001: nairovirus deubiquitinylating peptidase

(Topics flags: A Assay, S Structure, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Beckmann,L., Liessmann,F., Icker,M., Rieger,D., Schlegel,P., Urban,N., Schaefer,M., Meiler,J., Schoeder,C.T. and Tretbar,M.
   Identification and optimization of a small molecule inhibitor of the ovarian tumor protease of the Crimean-Congo hemorrhagic fever virus
   Bioorg Med Chem (2025) 120, 118093-118093. PubMed  Europe PubMed DOI  I
2020
2. Dzimianski,J.V., Mace,S.L., Williams,I.L., Freitas,B.T. and Pegan,S.D.
   Flipping the substrate preference of Hazara virus ovarian tumour domain protease through structure-based mutagenesis
   Acta Crystallogr D Struct Biol (2020) 76, 1114-1123. PubMed  Europe PubMed DOI  PMC  EPMC
2019
3. Dzimianski,J.V., Beldon,B.S., Daczkowski,C.M., Goodwin,O.Y., Scholte,F.E.M., Bergeron,E. and Pegan,S.D.
   Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity
   PLoS Pathog (2019) 15, e1007515-e1007515. PubMed  Europe PubMed DOI  S
4. Dzimianski,J.V., Scholte,F.E.M., Williams,I.L., Langley,C., Freitas,B.T., Spengler,J.R., Bergeron,E. and Pegan,S.D.
   Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases
   PLoS ONE (2019) 14, e0226415-e0226415. PubMed  Europe PubMed DOI  S
5. Scholte,F.E.M., Hua,B.L., Spengler,J.R., Dzimianski,J.V., Coleman-McCray,J.D., Welch,S.R., McMullan,L.K., Nichol,S.T., Pegan,S.D., Spiropoulou,C.F. and Bergeron,E.
   Stable occupancy of the Crimean-Congo hemorrhagic fever virus-encoded deubiquitinase blocks viral infection
   MBio (2019) 10 PubMed  Europe PubMed DOI
2017
6. Scholte,F.E.M., Zivcec,M., Dzimianski,J.V., Deaton,M.K., Spengler,J.R., Welch,S.R., Nichol,S.T., Pegan,S.D., Spiropoulou,C.F. and Bergeron,E.
   Crimean-Congo hemorrhagic fever virus suppresses innate immune responses via a ubiquitin and ISG15 specific protease
   Cell Rep (2017) 20, 2396-2407. PubMed  Europe PubMed DOI
2016
7. Kocabas,F. and Ergin,E.K.
   Identification of small molecule binding pocket for inhibition of Crimean - Congo hemorrhagic fever virus OTU protease
   Turk J Biol (2016) 40, 239-249. DOI  I
2015
8. Eisenmesser,E.Z., Capodagli,G.C., Armstrong,G.S., Holliday,M.J., Isern,N.G., Zhang,F. and Pegan,S.D.
   Inherent dynamics within the Crimean-Congo hemorrhagic fever virus protease are localized to the same region as substrate interactions
   Protein Sci (2015) 24, 651-660. PubMed  Europe PubMed DOI  S
9. Kocabas,F. and Aslan,G.S.
   Fluorometric CCHFV OTU protease assay with potent inhibitors
   Virus Genes (2015) 51, 190-197. PubMed  Europe PubMed DOI  A  I
2013
10. Capodagli,G.C., Deaton,M.K., Baker,E.A., Lumpkin,R.J. and Pegan,S.D.
    Diversity of ubiquitin and ISG15 specificity among nairoviruses' viral ovarian tumor domain proteases
    J Virol (2013) 87, 3815-3827. PubMed  Europe PubMed DOI  S
2012
11. Garcia-Sastre,A. and Levingston Macleod,J.M.
    Nairovirus deuquitinylating peptidase
    [ISSN:978-0-12-407743-0] (2012) 3, 2218-2224. DOI
12. Kessler,B.M.
    Otubains
    [ISSN:978-0-12-407743-0] (2012) 3, 2113-2120. DOI
13. van Kasteren,P.B., Beugeling,C., Ninaber,D.K., Frias-Staheli,N., van Boheemen,S., Garcia-Sastre,A., Snijder,E.J. and Kikkert,M.
    Arterivirus and nairovirus ovarian tumor domain-containing deubiquitinases target activated RIG-I to control innate immune signaling
    J Virol (2012) 86, 773-785. PubMed  Europe PubMed DOI
2011
14. Capodagli,G.C., McKercher,M.A., Baker,E.A., Masters,E.M., Brunzelle,J.S. and Pegan,S.D.
    Structural analysis of a viral ovarian tumor domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with covalently bonded ubiquitin
    J Virol (2011) 85, 3621-3630. PubMed  Europe PubMed DOI  S
15. Holzer,B., Bakshi,S., Bridgen,A. and Baron,M.D.
    Inhibition of interferon induction and action by the nairovirus nairobi sheep disease virus/ganjam virus
    PLoS ONE (2011) 6, e28594-e28594. PubMed  Europe PubMed DOI  PMC  EPMC
16. James,T.W., Frias-Staheli,N., Bacik,J.P., Levingston Macleod,J.M., Khajehpour,M., Garcia-Sastre,A. and Mark,B.L.
    Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease
    Proc Natl Acad Sci U S A (2011) 108, 2222-2227. PubMed  Europe PubMed DOI  S
17. Srinivasan,P., Kumar,S.P., Karthikeyan,M., Jeyakanthan,J., Jasrai,Y.T., Pandya,H.A., Rawal,R.M. and Patel,S.K.
    Epitope-based immunoinformatics and molecular docking studies of nucleocapsid protein and ovarian tumor domain of Crimean-Congo hemorrhagic fever virus
    Front Genet (2011) 2, 72-72. PubMed  Europe PubMed DOI  PMC  EPMC
2010
18. Bergeron,E., Albarino,C.G., Khristova,M.L. and Nichol,S.T.
    Crimean-Congo hemorrhagic fever virus-encoded ovarian tumor protease activity is dispensable for virus RNA polymerase function
    J Virol (2010) 84, 216-226. PubMed  Europe PubMed DOI
2007
19. Arguello,M.D. and Hiscott,J.
    Ub Surprised: viral ovarian tumor domain proteases remove ubiquitin and ISG15 conjugates
    Cell Host Microbe (2007) 2, 367-369. PubMed  Europe PubMed DOI
20. Frias-Staheli,N., Giannakopoulos,N.V., Kikkert,M., Taylor,S.L., Bridgen,A., Paragas,J., Richt,J.A., Rowland,R.R., Schmaljohn,C.S., Lenschow,D.J., Snijder,E.J., Garcia-Sastre,A. and Virgin,H.W.
    Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses
    Cell Host Microbe (2007) 2, 404-416. PubMed  Europe PubMed DOI  PMC  EPMC
2004
21. Honig,J.E., Osborne,J.C. and Nichol,S.T.
    Crimean-Congo hemorrhagic fever virus genome L RNA segment and encoded protein
    Virology (2004) 321, 29-35. PubMed  Europe PubMed DOI
22. [YEAR:30-3-2004]Kinsella,E., Martin,S.G., Grolla,A., Czub,M., Feldmann,H. and Flick,R.
    Sequence determination of the Crimean-Congo hemorrhagic fever virus L segment
    Virology (30-3-2004) 321, 23-28. PubMed  Europe PubMed DOI