Literature for peptidase C85.009: OTUD6B peptidase (Homo sapiens)

Summary Alignment Tree Sequences Sequence features Distribution Literature

(Topics flags: M Mutation, K Knockout. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Marotta,V.E., Sabat-Pospiech,D., Fielding,A.B., Ponsford,A.H., Thomaz,A., Querques,F., Morgan,M.R., Prior,I.A. and Coulson,J.M.
    OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival
    EMBO Rep PubMed  Europe PubMed DOI  K
  2. 2024
  3. Yang,M., Wei,Y., He,X. and Xia,C.
    The deubiquitinating protein OTUD6B promotes lung adenocarcinoma progression by stabilizing RIPK1
    Biol Direct19, 46-46. PubMed  Europe PubMed DOI  K
  4. 2023
  5. Li,L., Zhu,R., Zhou,H., Cui,C.P., Yu,X., Liu,Y., Yin,Y., Li,Y., Feng,R., Katz,J.P., Zhao,Y., Zhang,Y., Zhang,L. and Liu,Z.
    All-Trans Retinoic Acid Promotes a Tumor Suppressive OTUD6B-beta-TrCP-SNAIL Axis in Esophageal Squamous Cell Carcinoma and Enhances Immunotherapy
    Adv Sci (Weinh)10, e2207458-e2207458. PubMed  Europe PubMed DOI
  6. Ma,B., Wei,X., Zhou,S. and Yang,M.
    MCTS1 enhances the proliferation of laryngeal squamous cell carcinoma via promoting OTUD6B-1 mediated LIN28B deubiquitination
    Biochem Biophys Res Commun678, 128-134. PubMed  Europe PubMed DOI
  7. Wang,J., Zheng,H., Dong,C. and Xiong,S.
    Human OTUD6B positively regulates type I IFN antiviral innate immune responses by deubiquitinating and stabilizing IRF3
    MBio14, e0033223-e0033223. PubMed  Europe PubMed DOI
  8. 2022
  9. Borklu,E., Altunoglu,U., Eraslan,S. and Kayserili,H.
    A New Family with a Novel OTUD6B Mutation: Practicing Whole Exome Sequencing for Antenatal Diagnosis of Tetralogy of Fallot
    Mol Syndromol13, 206-211. PubMed  Europe PubMed DOI
  10. Cingoz,S., Soydemir,D., Oner,T.O., Karaca,E., Ozden,B., Kurul,S.H., Bayram,E., Coe,B.P., Nickerson,D.A. and Eichler,E.E.
    Novel biallelic variants affecting the OTU domain of the gene OTUD6B associate with severe intellectual disability syndrome and molecular dynamics simulations
    Eur J Med Genet65, 104497-104497. PubMed  Europe PubMed DOI
  11. 2021
  12. Weber,E., Schorpp,K. and Hadian,K.
    Studying OTUD6B-OTUB1 Protein-Protein Interaction by Low-Throughput GFP-Trap Assays and High-Throughput AlphaScreen Assays
    Methods Mol Biol2261, 381-394. PubMed  Europe PubMed DOI
  13. Zhou,Z., Cai,X., Zhu,J., Li,Z., Yu,G., Liu,X., Ouyang,G. and Xiao,W.
    Zebrafish otud6b Negatively Regulates Antiviral Responses by Suppressing K63-Linked Ubiquitination of irf3 and irf7
    J Immunol207, 244-256. PubMed  Europe PubMed DOI
  14. 2018
  15. Straniero,L., Rimoldi,V., Solda,G., Bellini,M., Biasucci,G., Asselta,R. and Duga,S.
    First replication of the involvement of OTUD6B in intellectual disability syndrome with seizures and dysmorphic features
    Front Genet9, 464-464. PubMed  Europe PubMed DOI
  16. 2017
  17. Santiago-Sim,T., Burrage,L.C., Ebstein,F., Tokita,M.J., Miller,M., Bi,W., Braxton,A.A., Rosenfeld,J.A., Shahrour,M., Lehmann,A., Cogne,B., Kury,S., Besnard,T., Isidor,B., Bezieau,S., Hazart,I., Nagakura,H., Immken,L.L., Littlejohn,R.O., Roeder,E., Kara,B., Hardies,K., Weckhuysen,S., May,P., Lemke,J.R., Elpeleg,O., Abu-Libdeh,B., James,K.N., Silhavy,J.L., Issa,M.Y., Zaki,M.S., Gleeson,J.G., Seavitt,J.R., Dickinson,M.E., Ljungberg,M.C., Wells,S., Johnson,S.J., Teboul,L., Eng,C.M., Yang,Y., Kloetzel,P.M., Heaney,J.D. and Walkiewicz,M.A.
    Biallelic variants in OTUD6B cause an intellectual disability syndrome associated with seizures and dysmorphic features
    Am J Hum Genet100, 676-688. PubMed  Europe PubMed DOI  M
  18. Sobol,A., Askonas,C., Alani,S., Weber,M.J., Ananthanarayanan,V., Osipo,C. and Bocchetta,M.
    Deubiquitinase OTUD6B isoforms are important regulators of growth and proliferation
    Mol Cancer Res15, 117-127. PubMed  Europe PubMed DOI  M