Literature for peptidase C85.003: OTUD3 peptidase (Homo sapiens)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: I Inhibitor, K Knockout. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Iwase,R., Maisonet,I.J., Lee,K., Buhrlage,S.J. and Cole,P.A.
    Deubiquitinase processing of a non-natural linkage of ubiquitinated-PTEN
    Bioorg Chem157, 108223-108223. PubMed  Europe PubMed DOI
  2. 2024
  3. Du,T., Gu,Q., Zhang,Y., Gan,Y., Liang,R., Yang,W., Lu,Y., Xu,C., Wu,J., Ma,R., Cao,H., Jiang,J., Wang,J. and Feng,J.
    Rolapitant treats lung cancer by targeting deubiquitinase OTUD3
    Cell Commun Signal22, 195-195. PubMed  Europe PubMed DOI
  4. Wu,L., Zhou,Z., Yu,Y., Cheng,C., Zhou,S., Yan,Y., Yu,B., Zhang,Y. and Liu,Z.
    Phosphorylation-dependent deubiquitinase OTUD3 regulates YY1 stability and promotes colorectal cancer progression
    Cell Death Dis15, 137-137. PubMed  Europe PubMed DOI  K
  5. 2023
  6. Job,F., Mai,C., Villavicencio-Lorini,P., Herfurth,J., Neuhaus,H., Hoffmann,K., Pfirrmann,T. and Hollemann,T.
    OTUD3: A Lys6 and Lys63 specific deubiquitinase in early vertebrate development
    Biochim Biophys Acta Gene Regul Mech1866, 194901-194901. PubMed  Europe PubMed DOI
  7. Li,J., Yang,D., Lin,Y., Xu,W., Zhao,S.M. and Wang,C.
    OTUD3 suppresses the mTORC1 signaling by deubiquitinating KPTN
    Front Pharmacol14, 1337732-1337732. PubMed  Europe PubMed DOI
  8. Lyu,H., Sun,L., Guan,Z., Li,J., Yin,C., Zhang,Y. and Jiang,H.
    Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS
    Cell Rep42, 112309-112309. PubMed  Europe PubMed DOI
  9. Xu,Q., He,L., Zhang,S., Di,X. and Jiang,H.
    Deubiquitinase OTUD3: a double-edged sword in immunity and disease
    Front Cell Dev Biol11, 1237530-1237530. PubMed  Europe PubMed DOI
  10. Zhang,Y., Du,T., Liu,N., Wang,J., Zhang,L., Cui,C.P., Li,C., Zhang,X., Wu,B., Zhang,J., Jiang,W., Zhang,Y., Zhang,Y., Li,H. and Li,P.
    Discovery of an OTUD3 inhibitor for the treatment of non-small cell lung cancer
    Cell Death Dis14, 378-378. PubMed  Europe PubMed DOI  I
  11. 2022
  12. Cai,X., Zhou,Z., Zhu,J., Liu,X., Ouyang,G., Wang,J., Li,Z., Li,X., Zha,H., Zhu,C., Rong,F., Tang,J., Liao,Q., Chen,X. and Xiao,W.
    Opposing effects of deubiquitinase OTUD3 in innate immunity against RNA and DNA viruses
    Cell Rep39, 110920-110920. PubMed  Europe PubMed DOI
  13. Jia,F., Li,H., Jiao,Q., Li,C., Fu,L., Cui,C., Jiang,H. and Zhang,L.
    Deubiquitylase OTUD3 prevents Parkinson's disease through stabilizing iron regulatory protein 2
    Cell Death Dis13, 418-418. PubMed  Europe PubMed DOI
  14. Zhou,N., Qi,H., Liu,J., Zhang,G., Liu,J., Liu,N., Zhu,M., Zhao,X., Song,C., Zhou,Z., Gong,J., Li,R., Bai,X., Jin,Y., Song,Y. and Yin,Y.
    Deubiquitinase OTUD3 regulates metabolism homeostasis in response to nutritional stresses
    Cell Metab34, 1023-1041. PubMed  Europe PubMed DOI
  15. 2021
  16. Xie,P., Chen,Y., Zhang,H., Zhou,G., Chao,Q., Wang,J., Liu,Y., Fang,J., Xie,J., Zhen,J., Wang,Z., Hao,L. and Huang,D.
    The deubiquitinase OTUD3 stabilizes ACTN4 to drive growth and metastasis of hepatocellular carcinoma
    Aging (Albany NY)13, 19317-19338. PubMed  Europe PubMed DOI
  17. 2020
  18. Zhang,Z., Fang,X., Wu,X., Ling,L., Chu,F., Li,J., Wang,S., Zang,J., Zhang,B., Ye,S., Zhang,L., Yang,B., Lin,S., Huang,H., Wang,A. and Zhou,F.
    Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity
    Mol Cell79, 304-319. PubMed  Europe PubMed DOI
  19. 2012
  20. Kessler,B.M.
    Otubains
    [ISSN:978-0-12-407743-0]3, 2113-2120. DOI