Literature for peptidase C85.001: OTUD5 peptidase (Homo sapiens)

(Topics flags: S Structure, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Jin,S.K. and Baek,K.H.
   Unraveling the role of deubiquitinating enzymes on cisplatin resistance in several cancers
   Biochim Biophys Acta Rev Cancer1880, 189297-189297. PubMed  Europe PubMed DOI  V
2. Zhang,J., Tian,T., Li,X., Xu,K., Lu,Y., Li,X., Zhao,X., Cui,Z., Wang,Z., Zhou,Y., Xu,Y., Li,H., Zhang,Y., Du,Y., Lv,L. and Xu,Y.
   p53 inhibits OTUD5 transcription to promote GPX4 degradation and induce ferroptosis in gastric cancer
   Clin Transl Med15, e70271-e70271. PubMed  Europe PubMed DOI
2024
3. Dai,J., Zhang,L., Zhang,R., Ge,J., Yao,F., Zhou,S., Xu,J., Yu,K., Xu,J., Jiang,L., Jin,K., Dai,X., Li,J. and Li,Q.
   Hepatocyte Deubiquitinating Enzyme OTUD5 Deficiency is a Key Aggravator for Metabolic Dysfunction-Associated Steatohepatitis by Disturbing Mitochondrial Homeostasis
   Cell Mol Gastroenterol Hepatol17, 399-421. PubMed  Europe PubMed DOI  K
4. Tang,Y., Wang,T., Gu,L., Xu,Y., Yang,Z., Zhu,W., Zhang,Q., Luo,J., Cao,J. and Jiao,Y.
   USP11 Exacerbates Radiation-Induced Pneumonitis by Activating Endothelial Cell Inflammatory Response via OTUD5-STING Signaling
   Int J Radiat Oncol Biol Phys119, 1261-1274. PubMed  Europe PubMed DOI  I
5. Tian,W., Li,H., Li,Y., Guo,J., Wang,H., Yang,B., Li,P., Cui,X. and Liu,L.
   A novel missense variant in OTUD5 causes X-linked multiple congenital anomalies-neurodevelopmental syndrome
   Mol Genet Genomic Med12, e2325-e2325. PubMed  Europe PubMed DOI
2023
6. de Vivo,A., Song,H., Lee,Y., Tirado-Class,N., Sanchez,A., Westerheide,S., Dungrawala,H. and Kee,Y.
   OTUD5 limits replication fork instability by organizing chromatin remodelers
   Nucleic Acids Res51, 10467-10483. PubMed  Europe PubMed DOI
7. Fu,L., Lu,K., Jiao,Q., Chen,X. and Jia,F.
   The Regulation and Double-Edged Roles of the Deubiquitinase OTUD5
   Cells12, PubMed  Europe PubMed DOI  V
8. Liu,L., Pang,J., Qin,D., Li,R., Zou,D., Chi,K., Wu,W., Rui,H., Yu,H., Zhu,W., Liu,K., Wu,X., Wang,J., Xu,P., Song,X., Cao,Y., Wang,J., Xu,F., Xue,L. and Chen,Y.
   Deubiquitinase OTUD5 as a Novel Protector against 4-HNE-Triggered Ferroptosis in Myocardial Ischemia/Reperfusion Injury
   Adv Sci (Weinh)10, e2301852-e2301852. PubMed  Europe PubMed DOI  I
9. Lou,B., Ma,G., Yu,X., Lv,F., Xu,F., Sun,C. and Chen,Y.
   Deubiquitinase OTUD5 promotes hepatitis B virus replication by removing K48-linked ubiquitination of HBV core/precore and upregulates HNF4a expressions by inhibiting the ERK1/2/mitogen-activated protein kinase pathway
   Cell Mol Life Sci80, 336-336. PubMed  Europe PubMed DOI
10. Masuta,Y., Otsuka,Y., Minaga,K., Honjo,H., Kudo,M. and Watanabe,T.
    Regulation of type I IFN responses by deubiquitinating enzyme A in inflammatory bowel diseases
    J Clin Biochem Nutr73, 103-107. PubMed  Europe PubMed DOI  V
2022
11. Hou,T., Dan,W., Liu,T., Liu,B., Wei,Y., Yue,C., Que,T., Ma,B., Lei,Y., Wang,Z., Zeng,J., Fan,Y. and Li,L.
    Deubiquitinase OTUD5 modulates mTORC1 signaling to promote bladder cancer progression
    Cell Death Dis13, 778-778. PubMed  Europe PubMed DOI
12. Li,X., Lu,B., Zhang,L., Yang,J., Cheng,Y. and Yan,D.
    Mechanism of OTUD5 in non-small cell lung cancer cell proliferation, invasion, and migration
    Bosn J Basic Med Sci22, 901-911. PubMed  Europe PubMed DOI
13. Pahi,Z.G., Kovacs,L., Szucs,D., Borsos,B.N., Deak,P. and Pankotai,T.
    Usp5, Usp34, and Otu1 deubiquitylases mediate DNA repair in Drosophila melanogaster
    Sci Rep12, 5870-5870. PubMed  Europe PubMed DOI  K
2021
14. Kabra,A. and Li,Y.
    Conformational Dynamics of Deubiquitinase A and Functional Implications
    Biochemistry60, 201-209. PubMed  Europe PubMed DOI
15. Saida,K., Fukuda,T., Scott,D.A., Sengoku,T., Ogata,K., Nicosia,A., Hernandez-Garcia,A., Lalani,S.R., Azamian,M.S., Streff,H., Liu,P., Dai,H., Mizuguchi,T., Miyatake,S., Asahina,M., Ogata,T., Miyake,N. and Matsumoto,N.
    OTUD5 Variants Associated With X-Linked Intellectual Disability and Congenital Malformation
    Front Cell Dev Biol9, 631428-631428. PubMed  Europe PubMed DOI
16. Zhang,Y., Fan,Y., Jing,X., Zhao,L., Liu,T., Wang,L., Zhang,L., Gu,S., Zhao,X. and Teng,Y.
    OTUD5-mediated deubiquitination of YAP in macrophage promotes M2 phenotype polarization and favors triple-negative breast cancer progression
    Cancer Lett504, 104-115. PubMed  Europe PubMed DOI
2020
17. Bai,M., Che,Y., Lu,K. and Fu,L.
    Analysis of deubiquitinase OTUD5 as a biomarker and therapeutic target for cervical cancer by bioinformatic analysis
    PeerJ8, e9146-e9146. PubMed  Europe PubMed DOI
18. Cho,J.H., Kim,K., Kim,S.A., Park,S., Park,B.O., Kim,J.H., Kim,S.Y., Kwon,M.J., Han,M.H., Lee,S.B., Park,B.C., Park,S.G., Kim,J.H. and Kim,S.
    Deubiquitinase OTUD5 is a positive regulator of mTORC1 and mTORC2 signaling pathways
    Cell Death Differ PubMed  Europe PubMed DOI  K
19. Kabra,A., Rumpa,E. and Li,Y.
    Modulation of conformational equilibrium by phosphorylation underlies the activation of deubiquitinase A
    J Biol Chem295, 3945-3951. PubMed  Europe PubMed DOI
20. Kang,X.Y., Zhang,J., Tang,L., Huang,L., Tong,J. and Fu,Q.
    OTU Deubiquitinase 5 inhibits the progression of non-small cell lung cancer via regulating p53 and PDCD5
    Chem Biol Drug Des PubMed  Europe PubMed DOI
21. Li,F., Sun,Q., Liu,K., Zhang,L., Lin,N., You,K., Liu,M., Kon,N., Tian,F., Mao,Z., Li,T., Tong,T., Qin,J., Gu,W., Li,D. and Zhao,W.
    OTUD5 cooperates with TRIM25 in transcriptional regulation and tumor progression via deubiquitination activity
    Nat Commun11, 4184-4184. PubMed  Europe PubMed DOI  K
2019
22. de Vivo,A., Sanchez,A., Yegres,J., Kim,J., Emly,S. and Kee,Y.
    The OTUD5-UBR5 complex regulates FACT-mediated transcription at damaged chromatin
    Nucleic Acids Res47, 729-746. PubMed  Europe PubMed DOI
23. Kabra,A., Benson,C.A. and Li,Y.
    Backbone (1)H, (13)C, and (15)N resonance assignments of deubiquitinase A in non-phosphorylated and phosphorylated forms
    Biomol NMR Assign13, 37-42. PubMed  Europe PubMed DOI  S
24. Li,F., Sun,Q., Liu,K., Han,H., Lin,N., Cheng,Z., Cai,Y., Tian,F., Mao,Z., Tong,T. and Zhao,W.
    The deubiquitinase OTUD5 regulates Ku80 stability and non-homologous end joining
    Cell Mol Life Sci76, 3861-3873. PubMed  Europe PubMed DOI
25. Yin,F., He,H., Zhang,B., Zheng,J., Wang,M., Zhang,M. and Cui,H.
    Effect of deubiquitinase ovarian tumor domain-containing protein 5 (OTUD5) on radiosensitivity of cervical cancer by regulating the ubiquitination of Akt and its mechanism
    Med Sci Monit25, 3469-3475. PubMed  Europe PubMed DOI
2018
26. Suen,D.F. and Schmidt,W.
    OTU5 Tunes environmental responses by sustaining chromatin structure
    Plant Signal Behav13, e1435963-e1435963. PubMed  Europe PubMed DOI
27. Suen,D.F., Tsai,Y.H., Cheng,Y.T., Radjacommare,R., Ahirwar,R.N., Fu,H. and Schmidt,W.
    The deubiquitinase OTU5 regulates root responses to phosphate starvation
    Plant Physiol176, 2441-2455. PubMed  Europe PubMed DOI
2017
28. Yen,M.R., Suen,D.F., Hsu,F.M., Tsai,Y.H., Fu,H., Schmidt,W. and Chen,P.Y.
    Deubiquitinating enzyme OTU5 contributes to DNA methylation patterns and is critical for phosphate nutrition signals
    Plant Physiol175, 1826-1838. PubMed  Europe PubMed DOI
2016
29. Keren,I. and Citovsky,V.
    The histone deubiquitinase OTLD1 targets euchromatin to regulate plant growth
    Sci Signal9, ra125-ra125. PubMed  Europe PubMed DOI
2013
30. Huang,O.W. and Cochran,A.G.
    Regulation of deubiquitinase proteolytic activity
    Curr Opin Struct Biol23, 806-811. PubMed  Europe PubMed DOI  S
31. Luo,J., Lu,Z., Lu,X., Chen,L., Cao,J., Zhang,S., Ling,Y. and Zhou,X.
    OTUD5 regulates p53 stability by deubiquitinating p53
    PLoS ONE8, e77682-e77682. PubMed  Europe PubMed DOI
2012
32. Huang,O.W., Ma,X., Yin,J., Flinders,J., Maurer,T., Kayagaki,N., Phung,Q., Bosanac,I., Arnott,D., Dixit,V.M., Hymowitz,S.G., Starovasnik,M.A. and Cochran,A.G.
    Phosphorylation-dependent activity of the deubiquitinase DUBA
    Nat Struct Mol Biol19, 171-175. PubMed  Europe PubMed DOI  S  I
33. Kessler,B.M.
    Otubains
    [ISSN:978-0-12-407743-0]3, 2113-2120. DOI
34. Renatus,M. and Farady,C.J.
    Phosphorylation meets proteolysis
    Structure20, 570-571. PubMed  Europe PubMed DOI
2011
35. Krichevsky,A., Zaltsman,A., Lacroix,B. and Citovsky,V.
    Involvement of KDM1C histone demethylase-OTLD1 otubain-like histone deubiquitinase complexes in plant gene repression
    Proc Natl Acad Sci U S A108, 11157-11162. PubMed  Europe PubMed DOI
2010
36. Gonzalez-Navajas,J.M., Law,J., Nguyen,K.P., Bhargava,M., Corr,M.P., Varki,N., Eckmann,L., Hoffman,H.M., Lee,J. and Raz,E.
    Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production
    J Exp Med207, 2799-2807. PubMed  Europe PubMed DOI
2007
37. Kayagaki,N., Phung,Q., Chan,S., Chaudhari,R., Quan,C., O'Rourke,K.M., Eby,M., Pietras,E., Cheng,G., Bazan,J.F., Zhang,Z., Arnott,D. and Dixit,V.M.
    DUBA: a deubiquitinase that regulates type I interferon production
    Science318, 1628-1632. PubMed  Europe PubMed DOI