Literature for peptidase C80.002: self-cleaving toxin A (Clostridium-type)

(Topics flags: S Structure, I Inhibitor, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

2024
1. Cummer,R., Grosjean,F., Bolteau,R., Vasegh,S.E., Veyron,S., Keogh,L., Trempe,J.F. and Castagner,B.
   Structure-Activity Relationship of Inositol Thiophosphate Analogs as Allosteric Activators of Clostridioides difficile Toxin B
   J Med Chem67, 16576-16597. PubMed  Europe PubMed DOI
2018
2. di Masi,A., Leboffe,L., Polticelli,F., Tonon,F., Zennaro,C., Caterino,M., Stano,P., Fischer,S., Hagele,M., Muller,M., Kleger,A., Papatheodorou,P., Nocca,G., Arcovito,A., Gori,A., Ruoppolo,M., Barth,H., Petrosillo,N., Ascenzi,P. and Di Bella,S.
   Human serum albumin is an essential component of the host defense mechanism against Clostridium difficile intoxication
   J Infect Dis218, 1424-1435. PubMed  Europe PubMed DOI
3. Zhang,Y., Li,S., Yang,Z., Shi,L., Yu,H., Salerno-Goncalves,R., Saint Fleur,A. and Feng,H.
   Cysteine protease-mediated autocleavage of Clostridium difficile toxins regulates their proinflammatory activity
   Cell Mol Gastroenterol Hepatol5, 611-625. PubMed  Europe PubMed DOI
2017
4. Hisao,G.S., Brothers,M.C., Ho,M., Wilson,B.A. and Rienstra,C.M.
   The membrane localization domains of two distinct bacterial toxins form a 4-helix-bundle in solution
   Protein Sci26, 497-504. PubMed  Europe PubMed DOI  S
2015
5. Bender,K.O., Garland,M., Ferreyra,J.A., Hryckowian,A.J., Child,M.A., Puri,A.W., Solow-Cordero,D.E., Higginbottom,S.K., Segal,E., Banaei,N., Shen,A., Sonnenburg,J.L. and Bogyo,M.
   A small-molecule antivirulence agent for treating Clostridium difficile infection
   Sci Transl Med7, 306ra148-306ra. PubMed  Europe PubMed DOI  I
6. Zhang,Y., Hamza,T., Gao,S. and Feng,H.
   Masking autoprocessing of Clostridium difficile toxin A by the C-terminus combined repetitive oligo peptides
   Biochem Biophys Res Commun459, 259-263. PubMed  Europe PubMed DOI
2014
7. Murase,T., Eugenio,L., Schorr,M., Hussack,G., Tanha,J., Kitova,E.N., Klassen,J.S. and Ng,K.K.
   Structural basis for antibody recognition in the receptor-binding domains of toxins A and B from Clostridium difficile
   J Biol Chem289, 2331-2343. PubMed  Europe PubMed DOI
8. Olling,A., Huls,C., Goy,S., Muller,M., Krooss,S., Rudolf,I., Tatge,H. and Gerhard,R.
   The combined repetitive oligopeptides of Clostridium difficile toxin A counteract premature cleavage of the glucosyl-transferase domain by stabilizing protein conformation
   Toxins (Basel)6, 2162-2176. PubMed  Europe PubMed DOI
2012
9. D'Urzo,N., Malito,E., Biancucci,M., Bottomley,M.J., Maione,D., Scarselli,M. and Martinelli,M.
   The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release
   FEBS J279, 3085-3097. PubMed  Europe PubMed DOI  S
10. Shen,A. and Bogyo,M.
    Self-cleaving bacterial toxins
    [ISSN:978-0-12-407743-0]3, 2350-2355. DOI
2011
11. Kreimeyer,I., Euler,F., Marckscheffel,A., Tatge,H., Pich,A., Olling,A., Schwarz,J., Just,I. and Gerhard,R.
    Autoproteolytic cleavage mediates cytotoxicity of Clostridium difficile toxin A
    Naunyn Schmiedebergs Arch Pharmacol383, 253-262. PubMed  Europe PubMed DOI
12. Savidge,T.C., Urvil,P., Oezguen,N., Ali,K., Choudhury,A., Acharya,V., Pinchuk,I., Torres,A.G., English,R.D., Wiktorowicz,J.E., Loeffelholz,M., Kumar,R., Shi,L., Nie,W., Braun,W., Herman,B., Hausladen,A., Feng,H., Stamler,J.S. and Pothoulakis,C.
    Host S-nitrosylation inhibits clostridial small molecule-activated glucosylating toxins
    Nat Med17, 1136-1141. PubMed  Europe PubMed DOI
2010
13. Pruitt,R.N., Chambers,M.G., Ng,K.K., Ohi,M.D. and Lacy,D.B.
    Structural organization of the functional domains of Clostridium difficile toxins A and B
    Proc Natl Acad Sci U S A107, 13467-13472. PubMed  Europe PubMed DOI  S
2009
14. Pruitt,R.N., Chagot,B., Cover,M., Chazin,W.J., Spiller,B. and Lacy,D.B.
    Structure-function analysis of inositol hexakisphosphate-induced autoprocessing in Clostridium difficile toxin A
    J Biol Chem284, 21934-21940. PubMed  Europe PubMed DOI  S
2008
15. Giesemann,T., Egerer,M., Jank,T. and Aktories,K.
    Processing of Clostridium difficile toxins
    J Med Microbiol57, 690-696. PubMed  Europe PubMed DOI
16. Yang,G., Zhou,B., Wang,J., He,X., Sun,X., Nie,W., Tzipori,S. and Feng,H.
    Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium
    BMC Microbiol8, 192-192. PubMed  Europe PubMed DOI  E
2007
17. Egerer,M., Giesemann,T., Jank,T., Satchell,K.J. and Aktories,K.
    Auto-catalytic cleavage of Clostridium difficile toxins A and B depends on cysteine protease activity
    J Biol Chem282, 25314-25321. PubMed  Europe PubMed DOI
2006
18. Greco,A., Ho,J.G., Lin,S.J., Palcic,M.M., Rupnik,M. and Ng,K.K.
    Carbohydrate recognition by Clostridium difficile toxin A
    Nat Struct Mol Biol13, 460-461. PubMed  Europe PubMed DOI  S
2005
19. Ho,J.G., Greco,A., Rupnik,M. and Ng,K.K.
    Crystal structure of receptor-binding C-terminal repeats from Clostridium difficile toxin A
    Proc Natl Acad Sci U S A102, 18373-18378. PubMed  Europe PubMed DOI  S
20. Voth,D.E. and Ballard,J.D.
    Clostridium difficile toxins: mechanism of action and role in disease
    Clin Microbiol Rev18, 247-263. PubMed  Europe PubMed DOI
1992
21. von Eichel-Streiber,C., Laufenberg-Feldmann,R., Sartingen,S., Schulze,J. and Sauerborn,M.
    Comparative sequence analysis of the Clostridium difficile toxins A and B
    Mol Gen Genet233, 260-268. PubMed  Europe PubMed DOI
1988
22. Lyerly,D.M., Krivan,H.C. and Wilkins,T.D.
    Clostridium difficile: its disease and toxins
    Clin Microbiol Rev1, 1-18. PubMed  Europe PubMed
1987
23. Henriques,B., Florin,I. and Thelestam,M.
    Cellular internalisation of Clostridium difficile toxin A
    Microb Pathog2, 455-463. PubMed  Europe PubMed