Literature for peptidase C78.003: ZUP1 g.p. (Homo sapiens)

Summary Alignment Sequences Sequence features Distribution Literature Substrates

(Topics flags: S Structure, T Target, L Localization. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Hao,W., Guo,M., Ji,X., Zhao,X., Zhu,M., Jin,Y., Wang,G., Feng,J., Lu,D. and Yin,Y.
    ZUP1 is a key component of the MAVS complex and acts as a protector of host against viral invasion
    FASEB J39, e70419-e70419. PubMed  Europe PubMed DOI
  2. 2021
  3. Ajadi,M.B., Soremekun,O.S., Adewumi,A.T., Kumalo,H.M. and Soliman,M.E.S.
    Functional Analysis of Single Nucleotide Polymorphism in ZUFSP Protein and Implication in Pathogenesis
    Protein J40, 28-40. PubMed  Europe PubMed DOI
  4. Ajadi,M.B., Soremekun,O.S., Elrashedy,A.A., Olotu,F.A., Kumalo,H.M. and Soliman,M.E.S.
    Probing Protein-Protein Interactions and Druggable Site Identification: Mechanistic Binding Events between Ubiquitin and Zinc Finger with UFM1-Specific Peptidase Domain Protein (ZUFSP)
    Comb Chem High Throughput Screen PubMed  Europe PubMed DOI
  5. Ajadi,M.B., Soremekun,O.S., Adewumi,A.T., Kumalo,H.M. and Soliman,M.E.S.
    Leveraging on Active Site Similarities; Identification of Potential Inhibitors of Zinc-Finger and UFSP domain Protein (ZUFSP)
    Curr Pharm Biotechnol22, 995-1004. PubMed  Europe PubMed DOI  T
  6. 2018
  7. Coleman,K.E. and Huang,T.T.
    In a class of its own: a new family of deubiquitinases promotes genome stability
    Mol Cell70, 1-3. PubMed  Europe PubMed DOI
  8. Haahr,P., Borgermann,N., Guo,X., Typas,D., Achuthankutty,D., Hoffmann,S., Shearer,R., Sixma,T.K. and Mailand,N.
    ZUFSP Deubiquitylates K63-linked polyubiquitin chains to promote genome stability
    Mol Cell70, 165-174. PubMed  Europe PubMed DOI
  9. Hermanns,T., Pichlo,C., Woiwode,I., Klopffleisch,K., Witting,K.F., Ovaa,H., Baumann,U. and Hofmann,K.
    A family of unconventional deubiquitinases with modular chain specificity determinants
    Nat Commun9, 799-799. PubMed  Europe PubMed DOI  S
  10. Hewings,D.S., Heideker,J., Ma,T.P., AhYoung,A.P., El Oualid,F., Amore,A., Costakes,G.T., Kirchhofer,D., Brasher,B., Pillow,T., Popovych,N., Maurer,T., Schwerdtfeger,C., Forrest,W.F., Yu,K., Flygare,J., Bogyo,M. and Wertz,I.E.
    Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes
    Nat Commun9, 1162-1162. PubMed  Europe PubMed DOI  L
  11. Kwasna,D., Abdul Rehman,S.A., Natarajan,J., Matthews,S., Madden,R., De Cesare,V., Weidlich,S., Virdee,S., Ahel,I., Gibbs-Seymour,I. and Kulathu,Y.
    Discovery and characterization of ZUFSP/ZUP1, a distinct deubiquitinase class important for genome stability
    Mol Cell70, 150-164. PubMed  Europe PubMed DOI  S