Literature for peptidase C78.002: UfSP2 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

(Topics flags: S Structure, M Mutation, K Knockout. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Zhao,S., Zhang,Y., Li,C., Zheng,Z. and Ma,M.
    Succinate-mediated Ufsp2 transcription promotes high glucose-stimulated pyroptosis in rat retinal Muller cells by activating NLRP3 inflammasome
    Biochem Biophys Res Commun (2025) 783, 152614-152614. PubMed  Europe PubMed DOI  K
  2. 2023
  3. Mattern,L., Begemann,M., Delbruck,H., Holschbach,P., Schroder,S., Schacht,S.M., Kurth,I. and Elbracht,M.
    Variant of the catalytic cysteine of UFSP2 leads to spondyloepimetaphyseal dysplasia type Di Rocco
    Bone Rep (2023) 18, 101683-101683. PubMed  Europe PubMed DOI  PMC  EPMC
  4. 2020
  5. Zhang,G., Tang,S., Wang,H., Pan,H., Zhang,W., Huang,Y., Kong,J., Wang,Y., Gu,J. and Wang,Y.
    UFSP2-related spondyloepimetaphyseal dysplasia: A confirmatory report
    Eur J Med Genet (2020) 63, 104021-104021. PubMed  Europe PubMed DOI
  6. 2018
  7. Di Rocco,M., Rusmini,M., Caroli,F., Madeo,A., Bertamino,M., Marre-Brunenghi,G. and Ceccherini,I.
    Novel spondyloepimetaphyseal dysplasia due to UFSP2 gene mutation
    Clin Genet (2018) 93, 671-674. PubMed  Europe PubMed DOI  M
  8. 2015
  9. Watson,C.M., Crinnion,L.A., Gleghorn,L., Newman,W.G., Ramesar,R., Beighton,P. and Wallis,G.A.
    Identification of a mutation in the ubiquitin-fold modifier 1-specific peptidase 2 gene, UFSP2, in an extended South African family with Beukes hip dysplasia
    S Afr Med J (2015) 105, 558-563. PubMed  Europe PubMed DOI  M
  10. 2014
  11. Chen,C., Itakura,E., Weber,K.P., Hegde,R.S. and de Bono,M.
    An ER complex of ODR-4 and ODR-8/Ufm1 specific protease 2 promotes GPCR maturation by a Ufm1-independent mechanism
    PLoS Genet (2014) 10, e1004082-e1004082. PubMed  Europe PubMed DOI  PMC  EPMC
  12. Yoo,H.M., Kang,S.H., Kim,J.Y., Lee,J.E., Seong,M.W., Lee,S.W., Ka,S.H., Sou,Y.S., Komatsu,M., Tanaka,K., Lee,S.T., Noh,D.Y., Baek,S.H., Jeon,Y.J. and Chung,C.H.
    Modification of ASC1 by UFM1 is crucial for ERalpha transactivation and breast cancer development
    Mol Cell (2014) 56, 261-274. PubMed  Europe PubMed DOI
  13. 2011
  14. Ha,B.H., Jeon,Y.J., Shin,S.C., Tatsumi,K., Komatsu,M., Tanaka,K., Watson,C.M., Wallis,G., Chung,C.H. and Kim,E.E.
    Structure of ubiquitin-fold modifier 1-specific protease UfSP2
    J Biol Chem (2011) 286, 10248-10257. PubMed  Europe PubMed DOI  S
  15. 2007
  16. Kang,S.H., Kim,G.R., Seong,M., Baek,S.H., Seol,J.H., Bang,O.S., Ovaa,H., Tatsumi,K., Komatsu,M., Tanaka,K. and Chung,C.H.
    Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2
    J Biol Chem (2007) 282, 5256-5262. PubMed  Europe PubMed DOI
  17. 2004
  18. [YEAR:5-5-2004]Komatsu,M., Chiba,T., Tatsumi,K., Iemura,S., Tanida,I., Okazaki,N., Ueno,T., Kominami,E., Natsume,T. and Tanaka,K.
    A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier
    EMBO J (5-5-2004) 23, 1977-1986. PubMed  Europe PubMed DOI  PMC  EPMC