Literature for family C65

(Topics flags: I Inhibitor, P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2026
1. Yang,J., Zhang,Y., Wang,Q. and Liu,H.
   Otubain deubiquitinases: Multi-layered regulators of cell fate, development, and stress responses across kingdoms
   iScience (2026) 29, 114527-114527. PubMed  Europe PubMed DOI  PMC  EPMC
2025
2. Deng,Y. and Liu,P.
   OTU deubiquitinases in disease: roles and targeting
   Trends Mol Med (2025) PubMed  Europe PubMed DOI  V
2023
3. Luo,R., Yang,K. and Xiao,W.
   Plant deubiquitinases: from structure and activity to biological functions
   Plant Cell Rep (2023) 42, 469-486. PubMed  Europe PubMed DOI  V
2022
4. Elu,N., Osinalde,N., Ramirez,J., Presa,N., Rodriguez,J.A., Prieto,G. and Mayor,U.
   Identification of substrates for human deubiquitinating enzymes (DUBs): An up-to-date review and a case study for neurodevelopmental disorders
   Semin Cell Dev Biol (2022) 132, 120-131. PubMed  Europe PubMed DOI
5. Newton,K. and Gitlin,A.D.
   Deubiquitinases in cell death and inflammation
   Biochem J (2022) 479, 1103-1119. PubMed  Europe PubMed DOI  PMC  EPMC  V
6. Sato,Y.
   Structural basis for the linkage specificity of ubiquitin-binding domain and deubiquitinase
   J Biochem (2022) 172, 1-7. PubMed  Europe PubMed DOI  V
2021
7. Snyder,N.A. and Silva,G.M.
   Deubiquitinating enzymes (DUBs): Regulation, homeostasis, and oxidative stress response
   J Biol Chem (2021) 297, 101077-101077. PubMed  Europe PubMed DOI  V
8. Zhu,Q., Fu,Y., Li,L., Liu,C.H. and Zhang,L.
   The functions and regulation of Otubains in protein homeostasis and diseases
   Ageing Res Rev (2021) 67, 101303-101303. PubMed  Europe PubMed DOI  V
2014
9. Bailey-Elkin,B.A., van Kasteren,P.B., Snijder,E.J., Kikkert,M. and Mark,B.L.
   Viral OTU deubiquitinases: a structural and functional comparison
   PLoS Pathog (2014) 10, e1003894-e1003894. PubMed  Europe PubMed DOI  PMC  EPMC
10. Isono,E. and Nagel,M.K.
    Deubiquitylating enzymes and their emerging role in plant biology
    Front Plant Sci (2014) 5, 56-56. PubMed  Europe PubMed DOI  PMC  EPMC
2013
11. Mevissen,T.E., Hospenthal,M.K., Geurink,P.P., Elliott,P.R., Akutsu,M., Arnaudo,N., Ekkebus,R., Kulathu,Y., Wauer,T., El Oualid,F., Freund,S.M., Ovaa,H. and Komander,D.
    OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis
    Cell (2013) 154, 169-184. PubMed  Europe PubMed DOI  PMC  EPMC  P
2010
12. Komander,D.
    Mechanism, specificity and structure of the deubiquitinases
    Subcell Biochem (2010) 54, 69-87. PubMed  Europe PubMed DOI
2005
13. Nijman,S.M., Luna-Vargas,M.P., Velds,A., Brummelkamp,T.R., Dirac,A.M., Sixma,T.K. and Bernards,R.
    A genomic and functional inventory of deubiquitinating enzymes
    Cell (2005) 123, 773-786. PubMed  Europe PubMed DOI
2003
14. Balakirev,M.Y., Tcherniuk,S.O., Jaquinod,M. and Chroboczek,J.
    Otubains: a new family of cysteine proteases in the ubiquitin pathway
    EMBO Rep (2003) 4, 517-522. PubMed  Europe PubMed DOI  PMC  EPMC  I
2002
15. Borodovsky,A., Ovaa,H., Kolli,N., Gan-Erdene,T., Wilkinson,K.D., Ploegh,H.L. and Kessler,B.M.
    Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family
    Chem Biol (2002) 9, 1149-1159. PubMed  Europe PubMed DOI
2000
16. Makarova,K.S., Aravind,L. and Koonin,E.V.
    A novel superfamily of predicted cysteine proteases from eukaryotes, viruses and Chlamydia pneumoniae
    Trends Biochem Sci (2000) 25, 50-52. PubMed  Europe PubMed DOI