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Literature for peptidase C64.003: A20 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, T Target, M Mutation, P Specificity, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Kohler,P., Ribeiro,A., Honarpisheh,M., von Rauchhaupt,E., Lorenz,G., Li,C., Martin,L., Steiger,S., Lindenmeyer,M., Schmaderer,C., Anders,H.J., Thomasova,D. and Lech,M.
    Podocyte A20/TNFAIP3 Controls Glomerulonephritis Severity via the Regulation of Inflammatory Responses and Effects on the Cytoskeleton
    Cells14, PubMed  Europe PubMed DOI
  2. Xiao,S., Shen,Y., Zhang,M., Liu,X., Cai,T. and Wang,F.
    VacA promotes pyroptosis via TNFAIP3/TRAF1 signaling to induce onset of atrophic gastritis
    Microbiol Res296, 128142-128142. PubMed  Europe PubMed DOI
    3. 2024
  3. Bagyinszky,E. and An,S.S.A.
    Genetic Mutations Associated With TNFAIP3 (A20) Haploinsufficiency and Their Impact on Inflammatory Diseases
    Int J Mol Sci25, PubMed  Europe PubMed DOI  V
  4. Culver-Cochran,A.E., Hassan,A., Hueneman,K., Choi,K., Ma,A., VanCauwenbergh,B., O'Brien,E., Wunderlich,M., Perentesis,J.P. and Starczynowski,D.T.
    Chemotherapy resistance in acute myeloid leukemia is mediated by A20 suppression of spontaneous necroptosis
    Nat Commun15, 9189-9189. PubMed  Europe PubMed DOI
  5. Karri,U., Harasimowicz,M., Carpio Tumba,M. and Schwartz,D.M.
    The Complexity of Being A20: From Biological Functions to Genetic Associations
    J Clin Immunol44, 76-76. PubMed  Europe PubMed DOI
  6. Kommer,A., Meineck,M., Classen,P. and Weinmann-Menke,J.
    A20 in Kidney Transplantation and Autoimmunity
    Int J Mol Sci25, PubMed  Europe PubMed DOI  V
  7. Mukohara,F., Iwata,K., Ishino,T., Inozume,T., Nagasaki,J., Ueda,Y., Suzawa,K., Ueno,T., Ikeda,H., Kawase,K., Saeki,Y., Kawashima,S., Yamashita,K., Kawahara,Y., Nakamura,Y., Honobe-Tabuchi,A., Watanabe,H., Dansako,H., Kawamura,T., Suzuki,Y., Honda,H., Mano,H., Toyooka,S., Kawazu,M. and Togashi,Y.
    Somatic mutations in tumor-infiltrating lymphocytes impact on antitumor immunity
    Proc Natl Acad Sci U S A121, e2320189121-e2320189121. PubMed  Europe PubMed DOI
  8. O'Sullivan,P.A., Aidarova,A., Afonina,I., Manils,J., Thurston,T.L.M., Instrell,R., Howell,M., Boeing,S., Ranawana,S., Herpels,M., Chetien,R., Bassa,M., Flynn,H.R., Frith,D., Snijders,A., Howes,A., Beyaert,R., Bowcock,A. and Ley,S.C.
    CARD14 SIGNALOSOME FORMATION IS ASSOCIATED WITH ITS ENDOSOMAL RELOCATION AND mTORC1-INDUCED KERATINOCYTE PROLIFERATION
    Biochem J PubMed  Europe PubMed DOI
  9. Petta,I., Thorp,M., Ciers,M., Blancke,G., Boon,L., Meese,T., Van Nieuwerburgh,F., Wullaert,A., Grencis,R., Elewaut,D., Van Loo,G. and Vereecke,L.
    Myeloid A20 is critical for alternative macrophage polarization and type-2 immune-mediated helminth resistance
    Front Immunol15, 1373745-1373745. PubMed  Europe PubMed DOI
  10. Sorada,T., Walinda,E. and Morimoto,D.
    Cyclization of ubiquitin chains reinforces their recognition by ZNF216
    FEBS Lett598, 2249-2258. PubMed  Europe PubMed DOI
  11. Wang,J., Rong,Q., Ye,L., Fang,B., Zhao,Y., Sun,Y., Zhou,H., Wang,D., He,J., Cui,Z., Zhang,Q., Kang,D. and Hu,L.
    Discovery of a Novel Orally Bioavailable FLT3-PROTAC Degrader for Efficient Treatment of Acute Myeloid Leukemia and Overcoming Resistance of FLT3 Inhibitors
    J Med Chem67, 7197-7223. PubMed  Europe PubMed DOI
    12. 2023
  12. El Khouri,E., Diab,F., Louvrier,C., Assrawi,E., Daskalopoulou,A., Nguyen,A., Piterboth,W., Deshayes,S., Desdoits,A., Copin,B., Dastot Le Moal,F., Karabina,S.A., Amselem,S., Aouba,A. and Giurgea,I.
    A critical region of A20 unveiled by missense TNFAIP3 variations that lead to autoinflammation
    elife12, PubMed  Europe PubMed DOI
  13. Ghoreshi,Z.A., Molaei,H.R. and Arefinia,N.
    The Role of DNA Viruses in Human Cancer
    Cancer Inform22, 11769351231154186-11769351231154186. PubMed  Europe PubMed DOI  V
  14. Giang,N.H., Lien,N.T.K., Trang,D.T., Huong,P.T., Hoang,N.H. and Xuan,N.T.
    Associations of A20, CYLD, Cezanne and JAK2 Genes and Immunophenotype with Psoriasis Susceptibility
    Medicina (Kaunas)59, PubMed  Europe PubMed DOI  M
  15. Liu,Y., Xu,K., Yao,Y. and Liu,Z.
    Current research into A20 mediation of allergic respiratory diseases and its potential usefulness as a therapeutic target
    Front Immunol14, 1166928-1166928. PubMed  Europe PubMed DOI  V
  16. Peng,Z.M., Zhang,Y.Y., Wei,D., Zhang,X.J., Liu,B., Peng,J. and Luo,X.J.
    MALT1 promotes necroptosis in stroke rat brain via targeting the A20/RIPK3 pathway
    Arch Biochem Biophys735, 109502-109502. PubMed  Europe PubMed DOI  K
  17. Rogers,N.M., Zammit,N., Nguyen-Ngo,D., Souilmi,Y., Minhas,N., Meijles,D.N., Self,E., Walters,S.N., Warren,J., Cultrone,D., El-Rashid,M., Li,J., Chtanova,T., O'Connell,P.J. and Grey,S.T.
    The impact of the cytoplasmic ubiquitin ligase TNFAIP3 gene variation on transcription factor NF-kappaB activation in acute kidney injury
    Kidney Int103, 1105-1119. PubMed  Europe PubMed DOI
  18. Sheveleva,O., Protasova,E., Nenasheva,T., Butorina,N., Melnikova,V., Gerasimova,T., Sakovnich,O., Kurinov,A., Grigor'eva,E., Medvedev,S. and Lyadova,I.
    A Model of iPSC-Derived Macrophages with TNFAIP3 Overexpression Reveals the Peculiarities of TNFAIP3 Protein Expression and Function in Human Macrophages
    Int J Mol Sci24, PubMed  Europe PubMed DOI
    19. 2022
  19. Bai,W., Huo,S., Li,J. and Shao,J.
    Advances in the Study of the Ubiquitin-Editing Enzyme A20
    Front Pharmacol13, 845262-845262. PubMed  Europe PubMed DOI
  20. Jantaree,P., Yu,Y., Chaithongyot,S., Tager,C., Sarabi,M.A., Meyer,T.F., Boccellato,F., Maubach,G. and Naumann,M.
    Human gastric fibroblasts ameliorate A20-dependent cell survival in co-cultured gastric epithelial cells infected by Helicobacter pylori
    Biochim Biophys Acta Mol Cell Res1869, 119364-119364. PubMed  Europe PubMed DOI
  21. Wang,Y.T., Liu,T.Y., Shen,C.H., Lin,S.Y., Hung,C.C., Hsu,L.C. and Chen,G.C.
    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
    Cell Rep38, 110354-110354. PubMed  Europe PubMed DOI
  22. Yang,F.M., Shen,L., Fan,D.D., Bai,Y., Li,B. and Lee,J.
    YAP9/A20 complex suppresses proinflammatory responses and provides novel anti-inflammatory therapeutic potentials
    Front Immunol13, 914381-914381. PubMed  Europe PubMed DOI
  23. Yokoyama,Y., Tamachi,T., Iwata,A., Maezawa,Y., Meguro,K., Yokota,M., Takatori,H., Suto,A., Suzuki,K., Hirose,K., Yamaguchi,N., Honda,H. and Nakajima,H.
    A20 (Tnfaip3) expressed in CD4(+) T cells suppresses Th2 cell-mediated allergic airway inflammation in mice
    Biochem Biophys Res Commun629, 47-53. PubMed  Europe PubMed DOI
    24. 2021
  24. Li,S., Zheng,X., Hu,Y., You,K. and Wang,J.
    RNF31 mediated ubiquitination of A20 aggravates inflammation and hepatocyte apoptosis through the TLR4/MyD88/NF-kappaB signaling pathway
    Chem Biol Interact348, 109623-109623. PubMed  Europe PubMed DOI  K
  25. Liu,S., Lv,X., Wei,X., Liu,C., Li,Q., Min,J., Hua,F., Zhang,X., Li,K., Li,P., Xiao,Y., Hu,Z. and Cui,B.
    TRIB3GSK-3beta interaction promotes lung fibrosis and serves as a potential therapeutic target
    Acta Pharm Sin B11, 3105-3119. PubMed  Europe PubMed DOI  K
  26. Meng,Z., Xu,R., Xie,L., Wu,Y., He,Q., Gao,P., He,X., Chen,Q., Xie,Q., Zhang,J. and Yang,Q.
    A20/Nrdp1 interaction alters the inflammatory signaling profile by mediating K48- and K63-linked polyubiquitination of effectors MyD88 and TBK1
    J Biol Chem297, 100811-100811. PubMed  Europe PubMed DOI
  27. Zhou,M., He,J., Shi,Y., Liu,X., Luo,S., Cheng,C., Ge,W., Qu,C., Du,P. and Chen,Y.
    ABIN3 negatively regulates necroptosis-induced intestinal inflammation through recruiting A20 and restricting the ubiquitination of RIPK3 in inflammatory bowel disease
    J Crohns Colitis15, 99-114. PubMed  Europe PubMed DOI
  28. Zou,J., Xia,H., Zhang,C., Xu,H., Tang,Q., Zhu,G., Li,J. and Bi,F.
    Casp8 acts through A20 to inhibit PD-L1 expression: The mechanism and its implication in immunotherapy
    Cancer Sci112, 2664-2678. PubMed  Europe PubMed DOI
    29. 2020
  29. Chen,D., Ma,L., Hu,T., Liu,J., Chen,B., Yang,P. and Liu,Z.
    A20 Restores impaired intestinal permeability and inhibits Th2 response in mice with colitis
    Dig Dis Sci65, 1340-1347. PubMed  Europe PubMed DOI
  30. Downey,A., Olcott,M., Spector,D., Bird,K., Ter Doest,A., Pierce,Z., Quach,E., Sparks,S., Super,C., Naifeh,J., Powers,A., White,M. and Hensley,K.
    Stable knockout of lanthionine synthase C-like protein-1 (LanCL1) from HeLa cells indicates a role for LanCL1 in redox regulation of deubiquitinating enzymes
    Free Radic Biol Med161, 115-124. PubMed  Europe PubMed DOI
  31. Feng,Y., Zhang,Y., Cai,Y., Liu,R., Lu,M., Li,T., Fu,Y., Guo,M., Huang,H., Ou,Y. and Chen,Y.
    A20 targets PFKL and glycolysis to inhibit the progression of hepatocellular carcinoma
    Cell Death Dis11, 89-89. PubMed  Europe PubMed DOI
  32. Feoktistova,M., Makarov,R., Brenji,S., Schneider,A.T., Hooiveld,G.J., Luedde,T., Leverkus,M., Yazdi,A.S. and Panayotova-Dimitrova,D.
    A20 Promotes ripoptosome formation and TNF-induced apoptosis via cIAPs regulation and NIK stabilization in keratinocytes
    Cells9, PubMed  Europe PubMed DOI
  33. Liang,J., Zhang,J.J., Huang,H.I., Kanayama,M., Youssef,N., Jin,Y.J., Reyes,E.Y., Abram,C.L., Yang,S., Lowell,C.A., Wang,D., Shao,L., Shinohara,M.L., Zhang,J.Y. and Hammer,G.E.
    The ubiquitin-modifying enzyme A20 terminates C-type lectin receptor signals and is a suppressor of host defense against systemic fungal infection
    Infect Immun PubMed  Europe PubMed DOI
  34. Martens,A., Priem,D., Hoste,E., Vetters,J., Rennen,S., Catrysse,L., Voet,S., Deelen,L., Sze,M., Vikkula,H., Slowicka,K., Hochepied,T., Iliaki,K., Wullaert,A., Janssens,S., Lamkanfi,M., Beyaert,R., Armaka,M., Bertrand,M.J.M. and Van Loo,G.
    Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities
    Nat Immunol21, 381-387. PubMed  Europe PubMed DOI
  35. Mei,S., Ruan,H., Ma,Q. and Yao,W.D.
    The ubiquitin-editing enzyme A20 regulates synapse remodeling and efficacy
    Brain Res1727, 146569-146569. PubMed  Europe PubMed DOI
  36. Mooney,E.C. and Sahingur,S.E.
    The Ubiquitin System and A20: Implications in Health and Disease
    J Dent Res22034520949486-22034520949486. PubMed  Europe PubMed DOI  V
  37. Rasaei,R., Sarodaya,N., Kim,K.S., Ramakrishna,S. and Hong,S.H.
    Importance of Deubiquitination in Macrophage-Mediated Viral Response and Inflammation
    Int J Mol Sci21, PubMed  Europe PubMed DOI  V
  38. Razani,B., Malynn,B.A. and Ma,A.
    Preserving immune homeostasis with A20
    Adv Immunol148, 1-48. PubMed  Europe PubMed DOI
  39. Song,Z., Wei,W., Xiao,W., Al-Saleem,E.D., Nejati,R., Chen,L., Yin,J., Fabrizio,J., Petrus,M.N., Waldmann,T.A. and Yang,Y.
    Essential role of the linear ubiquitin chain assembly complex and TAK1 kinase in A20 mutant Hodgkin lymphoma
    Proc Natl Acad Sci U S A117, 28980-28991. PubMed  Europe PubMed DOI
  40. Sun,S.C.
    A20 restricts inflammation via ubiquitin binding
    Nat Immunol21, 362-364. PubMed  Europe PubMed DOI
  41. Xiao,Y., Huang,Q., Wu,Z. and Chen,W.
    Roles of protein ubiquitination in inflammatory bowel disease
    Immunobiology225, 152026-152026. PubMed  Europe PubMed DOI  V
  42. Yan,K., Wu,C., Ye,Y., Li,L., Wang,X., He,W., Ren,S. and Xu,Y.
    A20 inhibits osteoclastogenesis via TRAF6-dependent autophagy in human periodontal ligament cells under hypoxia
    Cell Prolife12778-e12778. PubMed  Europe PubMed DOI
    43. 2019
  43. Chen,X., Qian,B., Kong,X., Hao,J., Ye,Y., Yang,K., Xu,T. and Zhang,F.
    A20 protects neuronal apoptosis stimulated by lipopolysaccharide-induced microglial exosomes
    Neurosci Lett712, 134480-134480. PubMed  Europe PubMed DOI
  44. Duan,R., Liu,Q., Li,J., Bian,X., Yuan,Q., Li,Y., Long,F., Gao,S., Wei,S., Li,P., Gao,F., Sun,W., Li,X. and Liu,Q.
    A de novo frameshift mutation in TNFAIP3 impairs A20 deubiquitination function to cause neuropsychiatric systemic lupus erythematosus
    J Clin Immunol39, 795-804. PubMed  Europe PubMed DOI  M
  45. Priem,D., Devos,M., Druwe,S., Martens,A., Slowicka,K., Ting,A.T., Pasparakis,M., Declerq,W., Vandenabeele,P., Van Loo,G. and Bertrand,M.J.M.
    A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms
    Cell Death Dis10, 692-692. PubMed  Europe PubMed DOI
  46. Zammit,N.W., Siggs,O.M., Gray,P.E., Horikawa,K., Langley,D.B., Walters,S.N., Daley,S.R., Loetsch,C., Warren,J., Yap,J.Y., Cultrone,D., Russell,A., Malle,E.K., Villanueva,J.E., Cowley,M.J., Gayevskiy,V., Dinger,M.E., Brink,R., Zahra,D., Chaudhri,G., Karupiah,G., Whittle,B., Roots,C., Bertram,E., Yamada,M., Jeelall,Y., Enders,A., Clifton,B.E., Mabbitt,P.D., Jackson,C.J., Watson,S.R., Jenne,C.N., Lanier,L.L., Wiltshire,T., Spitzer,M.H., Nolan,G.P., Schmitz,F., Aderem,A., Porebski,B.T., Buckle,A.M., Abbott,D.W., Ziegler,J.B., Craig,M.E., Benitez-Aguirre,P., Teo,J., Tangye,S.G., King,C., Wong,M., Cox,M.P., Phung,W., Tang,J., Sandoval,W., Wertz,I.E., Christ,D., Goodnow,C.C. and Grey,S.T.
    Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity
    Nat Immunol20, 1299-1310. PubMed  Europe PubMed DOI  M
    47. 2018
  47. Bombassaro,B., Ignacio-Souza,L.M., Nunez,C.E., Razolli,D.S., Pedro,R.M., Coope,A., Araujo,E.P., Chaim,E.A. and Velloso,L.A.
    A20 deubiquitinase controls PGC-1alpha expression in the adipose tissue
    Lipids Health Dis17, 90-90. PubMed  Europe PubMed DOI
  48. Hyeon,J., Lee,B., Shin,S.H., Yoo,H.Y., Kim,S.J., Kim,W.S., Park,W.Y. and Ko,Y.H.
    Targeted deep sequencing of gastric marginal zone lymphoma identified alterations of TRAF3 and TNFAIP3 that were mutually exclusive for MALT1 rearrangement
    Mod Pathol31, 1418-1428. PubMed  Europe PubMed DOI  M
  49. Nakamura,B.N., Glazier,A., Kattah,M.G., Duong,B., Jia,Y., Campo,D. and Shao,L.
    A20 regulates canonical wnt-signaling through an interaction with RIPK4
    PLoS ONE13, e0195893-e0195893. PubMed  Europe PubMed DOI  K
  50. Soni,D., Wang,D.M., Regmi,S.C., Mittal,M., Vogel,S.M., Schluter,D. and Tiruppathi,C.
    Deubiquitinase function of A20 maintains and repairs endothelial barrier after lung vascular injury
    Cell Death Discov4, 60-60. PubMed  Europe PubMed DOI
  51. Van Quickelberghe,E., Martens,A., Goeminne,L.J.E., Clement,L., Van Loo,G. and Gevaert,K.
    Identification of Immune-Responsive Gene 1 (IRG1) as a target of A20
    J Proteome Res17, 2182-2191. PubMed  Europe PubMed DOI  K
    52. 2017
  52. Lork,M., Verhelst,K. and Beyaert,R.
    CYLD, A20 and OTULIN deubiquitinases in NF-kappaB signaling and cell death: so similar, yet so different
    Cell Death Differ24, 1172-1183. PubMed  Europe PubMed DOI
    53. 2016
  53. Catrysse,L., Farhang Ghahremani,M., Vereecke,L., Youssef,S.A., Mc Guire,C., Sze,M., Weber,A., Heikenwalder,M., de Bruin,A., Beyaert,R. and Van Loo,G.
    A20 prevents chronic liver inflammation and cancer by protecting hepatocytes from death
    Cell Death Dis7, e2250-e2250. PubMed  Europe PubMed DOI  K
  54. Chang,Y.C., Chang,Y.S., Chang,C.C., Liu,T.C., Ko,Y.C., Lee,C.C., Chang,S.J. and Chang,J.G.
    Development of a high-resolution melting method for the screening of TNFAIP3 gene mutations
    Oncol Rep35, 2936-2942. PubMed  Europe PubMed DOI  M
    55. 2015
  55. Abbasi,A., Forsberg,K. and Bischof,F.
    The role of the ubiquitin-editing enzyme A20 in diseases of the central nervous system and other pathological processes
    Front Mol Neurosci8, 21-21. PubMed  Europe PubMed DOI
  56. Duong,B.H., Onizawa,M., Oses-Prieto,J.A., Advincula,R., Burlingame,A., Malynn,B.A. and Ma,A.
    A20 restricts ubiquitination of pro-interleukin-1beta protein complexes and suppresses NLRP3 inflammasome activity
    Immunity42, 55-67. PubMed  Europe PubMed DOI
  57. Enesa,K., Moll,H.P., Luong,L., Ferran,C. and Evans,P.C.
    A20 suppresses vascular inflammation by recruiting proinflammatory signaling molecules to intracellular aggresomes
    FASEB J29, 1869-1878. PubMed  Europe PubMed DOI
  58. Nakagawa,M.M., Thummar,K., Mandelbaum,J., Pasqualucci,L. and Rathinam,C.V.
    Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescence
    J Exp Med212, 203-216. PubMed  Europe PubMed DOI  K
  59. Onizawa,M., Oshima,S., Schulze-Topphoff,U., Oses-Prieto,J.A., Lu,T., Tavares,R., Prodhomme,T., Duong,B., Whang,M.I., Advincula,R., Agelidis,A., Barrera,J., Wu,H., Burlingame,A., Malynn,B.A., Zamvil,S.S. and Ma,A.
    The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis
    Nat Immunol16, 618-627. PubMed  Europe PubMed DOI
  60. Pfoh,R., Lacdao,I.K. and Saridakis,V.
    Deubiquitinases and the new therapeutic opportunities offered to cancer
    Endocr Relat Cancer22, T35-T54. PubMed  Europe PubMed DOI  V  T
  61. Wertz,I.E., Newton,K., Seshasayee,D., Kusam,S., Lam,C., Zhang,J., Popovych,N., Helgason,E., Schoeffler,A., Jeet,S., Ramamoorthi,N., Kategaya,L., Newman,R.J., Horikawa,K., Dugger,D., Sandoval,W., Mukund,S., Zindal,A., Martin,F., Quan,C., Tom,J., Fairbrother,W.J., Townsend,M., Warming,S., Devoss,J., Liu,J., Dueber,E., Caplazi,P., Lee,W.P., Goodnow,C.C., Balazs,M., Yu,K., Kolumam,G. and Dixit,V.M.
    Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
    Nature528, 370-375. PubMed  Europe PubMed DOI
  62. Yamaguchi,N. and Yamaguchi,N.
    The seventh zinc finger motif of A20 is required for the suppression of TNF-alpha-induced apoptosis
    FEBS Lett589, 1369-1375. PubMed  Europe PubMed DOI
    63. 2014
  63. Catrysse,L., Vereecke,L., Beyaert,R. and Van Loo,G.
    A20 in inflammation and autoimmunity
    Trends Immunol35, 22-31. PubMed  Europe PubMed DOI  V
  64. De,A., Dainichi,T., Rathinam,C.V. and Ghosh,S.
    The deubiquitinase activity of A20 is dispensable for NF-kappaB signaling
    EMBO Rep15, 775-783. PubMed  Europe PubMed DOI
  65. Enesa,K. and Evans,P.
    The biology of A20-like molecules
    Adv Exp Med Biol809, 33-48. PubMed  Europe PubMed  V
  66. Liu,X., He,F., Pang,R., Zhao,D., Qiu,W., Shan,K., Zhang,J., Lu,Y., Li,Y. and Wang,Y.
    Interleukin-17 (IL-17)-induced microRNA 873 (miR-873) contributes to the pathogenesis of experimental autoimmune encephalomyelitis by targeting A20 ubiquitin-editing enzyme
    J Biol Chem289, 28971-28986. PubMed  Europe PubMed DOI
  67. Wertz,I. and Dixit,V.
    A20 - a bipartite ubiquitin editing enzyme with immunoregulatory potential
    Adv Exp Med Biol809, 1-12. PubMed  Europe PubMed
    68. 2013
  68. Garg,A.V., Ahmed,M., Vallejo,A.N., Ma,A. and Gaffen,S.L.
    The deubiquitinase a20 mediates feedback inhibition of interleukin-17 receptor signaling
    Sci Signal6, ra44-ra44. PubMed  Europe PubMed DOI
  69. Huang,O.W. and Cochran,A.G.
    Regulation of deubiquitinase proteolytic activity
    Curr Opin Struct Biol23, 806-811. PubMed  Europe PubMed DOI  S
  70. Kulathu,Y., Garcia,F.J., Mevissen,T.E., Busch,M., Arnaudo,N., Carroll,K.S., Barford,D. and Komander,D.
    Regulation of A20 and other OTU deubiquitinases by reversible oxidation
    Nat Commun4, 1569-1569. PubMed  Europe PubMed DOI  S
  71. Lu,T.T., Onizawa,M., Hammer,G.E., Turer,E.E., Yin,Q., Damko,E., Agelidis,A., Shifrin,N., Advincula,R., Barrera,J., Malynn,B.A., Wu,H. and Ma,A.
    Dimerization and ubiquitin mediated recruitment of A20, a complex deubiquitinating enzyme
    Immunity38, 896-905. PubMed  Europe PubMed DOI
  72. Yamaguchi,N., Oyama,M., Kozuka-Hata,H. and Inoue,J.
    Involvement of A20 in the molecular switch that activates the non-canonical NF-kB pathway
    Sci Rep3, 2568-2568. PubMed  Europe PubMed DOI
    73. 2012
  73. Chu,Y., Soberon,V., Glockner,L., Beyaert,R., Massoumi,R., Van Loo,G., Krappmann,D. and Schmidt-Supprian,M.
    A20 and CYLD do not share significant overlapping functions during B cell development and activation
    J Immunol189, 4437-4443. PubMed  Europe PubMed DOI
  74. Kessler,B.M.
    Otubains
    [ISSN:978-0-12-407743-0]3, 2113-2120. DOI
  75. Ma,A. and Malynn,B.A.
    A20: linking a complex regulator of ubiquitylation to immunity and human disease
    Nat Rev Immunol12, 774-785. PubMed  Europe PubMed DOI  V
  76. Nomoto,J., Hiramoto,N., Kato,M., Sanada,M., Maeshima,A.M., Taniguchi,H., Hosoda,F., Asakura,Y., Munakata,W., Sekiguchi,N., Maruyama,D., Watanabe,T., Nakagama,H., Takeuchi,K., Tobinai,K., Ogawa,S. and Kobayashi,Y.
    Deletion of the TNFAIP3/A20 gene detected by FICTION analysis in classical Hodgkin lymphoma
    BMC Cancer12, 457-457. PubMed  Europe PubMed DOI  M
  77. Pranski,E.L., Van Sanford,C.D., Dalal,N.V., Orr,A.L., Karmali,D., Cooper,D.S., Costa,N., Heilman,C.J., Gearing,M., Lah,J.J., Levey,A.I. and Betarbet,R.S.
    Comparative distribution of protein components of the A20 ubiquitin-editing complex in normal human brain
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