Literature for peptidase C64.001: Cezanne peptidase

(Topics flags: M Mutation, P Specificity, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Ding,C., Cao,L., Wang,R., Wu,Q., Li,M., Zhang,J., Thorne,R.F., Li,J., Ma,J., Wu,M. and Cang,S.
   OTUD7B is a new deubiquitinase targeting p53
   Theranostics15, 2121-2138. PubMed  Europe PubMed DOI  K
2024
2. Chen,X., He,L., Zhong,H., Yan,C., Ke,B. and Shi,L.
   The suppression of OTUD7B by miR-491-5p enhances the ubiquitination of VEGFA to suppress vascular mimicry in non-small cell lung cancer
   J Gene Med26, e3743-e3743. PubMed  Europe PubMed DOI
3. Guo,Z. and Guo,L.
   OTUD7B deubiquitinates and stabilizes YAP1 to upregulate NUAK2 expression, thus accelerating gastric cancer procession
   Dig Liver Dis56, 352-362. PubMed  Europe PubMed DOI  K
4. Kim,Y.J., Lee,H.J., Kim,K.H., Cho,S.P. and Jung,J.Y.
   OTUD7B knockdown inhibits proliferation and autophagy through AKT/mTOR signaling pathway in human prostate cancer cell
   Discov Oncol15, 247-247. PubMed  Europe PubMed DOI  K
5. Sun,C., Bai,J., Sun,J., Sun,Y., Zhang,F., Li,H., Liu,Y., Meng,L. and Wang,X.
   OTU deubiquitinase 7B facilitates the hyperthermia-induced inhibition of lung cancer progression through enhancing Smac-mediated mitochondrial dysfunction
   Environ Toxicol39, 1989-2005. PubMed  Europe PubMed DOI
6. Sun,J., Jin,X. and Li,Y.
   OTUD7B inhibited hepatic injury from NAFLD by inhibiting K48-linked ubiquitination and degradation of beta-catenin
   Biochim Biophys Acta Mol Basis Dis1871, 167555-167555. PubMed  Europe PubMed DOI
2023
7. Chen,J., Bolhuis,D.L., Laggner,C., Kong,D., Yu,L., Wang,X., Emanuele,M.J., Brown,N.G. and Liu,P.
   AtomNet-Aided OTUD7B Inhibitor Discovery and Validation
   Cancers (Basel)15, PubMed  Europe PubMed DOI  I
8. Giang,N.H., Lien,N.T.K., Trang,D.T., Huong,P.T., Hoang,N.H. and Xuan,N.T.
   Associations of A20, CYLD, Cezanne and JAK2 Genes and Immunophenotype with Psoriasis Susceptibility
   Medicina (Kaunas)59, PubMed  Europe PubMed DOI  M
9. Harit,K., Bhattacharjee,R., Matuschewski,K., Becker,J., Kalinke,U., Schluter,D. and Nishanth,G.
   The deubiquitinating enzyme OTUD7b protects dendritic cells from TNF-induced apoptosis by stabilizing the E3 ligase TRAF2
   Cell Death Dis14, 480-480. PubMed  Europe PubMed DOI
10. Ilter,M., Schulze-Niemand,E., Naumann,M. and Stein,M.
    Structural Dynamics of Lys11-Selective Deubiquitinylase Cezanne-1 during the Catalytic Cycle
    J Chem Inf Model63, 2084-2094. PubMed  Europe PubMed DOI
2022
11. Xie,W., Tian,S., Yang,J., Cai,S., Jin,S., Zhou,T., Wu,Y., Chen,Z., Ji,Y. and Cui,J.
    OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity
    Autophagy1-15. PubMed  Europe PubMed DOI  K
12. Zhang,J., Zha,Y., Jiao,Y., Li,Y., Wang,J. and Zhang,S.
    OTUD7B (Cezanne) ameliorates fibrosis after myocardial infarction via FAK-ERK/P38 MAPK signaling pathway
    Arch Biochem Biophys724, 109266-109266. PubMed  Europe PubMed DOI  K
2021
13. An,W., Luong,L.A., Bowden,N.P., Yang,M., Wu,W., Zhou,X., Liu,C., Niu,K., Luo,J., Zhang,C., Sun,X., Poston,R., Zhang,L., Evans,P.C. and Xiao,Q.
    Cezanne is a critical regulator of pathological arterial remodelling by targeting beta-catenin signalling
    Cardiovasc Res PubMed  Europe PubMed DOI  K
14. Cheng,J., Fan,Y.Q., Jiang,H.X., Chen,S.F., Chen,J., Liao,X.Y., Zou,Y.Y., Lan,H.Y., Cui,Y., Chen,Z.B., Chen,Q.X. and Wan,Q.
    Transcranial direct-current stimulation protects against cerebral ischemia-reperfusion injury through regulating Cezanne-dependent signaling
    Exp Neurol345, 113818-113818. PubMed  Europe PubMed DOI
15. Gong,Z., Li,A., Ding,J., Li,Q., Zhang,L., Li,Y., Meng,Z., Chen,F., Huang,J., Zhou,D., Hu,R., Ye,J., Liu,W. and You,H.
    OTUD7B Deubiquitinates LSD1 to Govern Its Binding Partner Specificity, Homeostasis, and Breast Cancer Metastasis
    Adv Sci (Weinh)e2004504-e2004504. PubMed  Europe PubMed DOI
16. Snyder,N.A. and Silva,G.M.
    Deubiquitinating enzymes (DUBs): Regulation, homeostasis, and oxidative stress response
    J Biol Chem297, 101077-101077. PubMed  Europe PubMed DOI  V
2020
17. Chen,X., Pang,Z., Wang,Y., Zhu,L., Liu,J. and Du,J.
    Cezanne contributes to cancer progression by playing a key role in the deubiquitination of IGF-1R
    Am J Cancer Res10, 4342-4356. PubMed  Europe PubMed  K
18. Mader,J., Huber,J., Bonn,F., Dotsch,V., Rogov,V.V. and Bremm,A.
    Oxygen-dependent asparagine hydroxylation of the ubiquitin-associated (UBA) domain in Cezanne regulates ubiquitin binding
    J Biol Chem295, 2160-2174. PubMed  Europe PubMed DOI
2019
19. Bonacci,T. and Emanuele,M.J.
    Impressionist portraits of mitotic exit: APC/C, K11-linked ubiquitin chains and Cezanne
    Cell Cycle18, 652-660. PubMed  Europe PubMed DOI
20. Lei,S., He,Z., Chen,T., Guo,X., Zeng,Z., Shen,Y. and Jiang,J.
    Long noncoding RNA 00976 promotes pancreatic cancer progression through OTUD7B by sponging miR-137 involving EGFR/MAPK pathway
    J Exp Clin Cancer Res38, 470-470. PubMed  Europe PubMed DOI
21. Wu,X., Liu,S., Sagum,C., Chen,J., Singh,R., Chaturvedi,A., Horton,J.R., Kashyap,T.R., Fushman,D., Cheng,X., Bedford,M.T. and Wang,B.
    Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne
    Genes Dev33, 1702-1717. PubMed  Europe PubMed DOI
22. Yin,Z., Yang,L., Wu,F., Fan,J., Xu,J., Jin,Y. and Yang,G.
    Reactive oxygen specie-mediated Cezanne inactivation by oxidation of its catalytic cysteine residue in hepatocellular carcinoma
    Oncol Res27, 1069-1077. PubMed  Europe PubMed DOI
2018
23. Bonacci,T., Suzuki,A., Grant,G.D., Stanley,N., Cook,J.G., Brown,N.G. and Emanuele,M.J.
    Cezanne/OTUD7B is a cell cycle-regulated deubiquitinase that antagonizes the degradation of APC/C substrates
    EMBO J37, e98701-e98701. PubMed  Europe PubMed DOI
24. Ji,Y., Cao,L., Zeng,L., Zhang,Z., Xiao,Q., Guan,P., Chen,S., Chen,Y., Wang,M. and Guo,D.
    The N-terminal ubiquitin-associated domain of Cezanne is crucial for its function to suppress NF-kappaB pathway
    J Cell Biochem119, 1979-1991. PubMed  Europe PubMed DOI
2017
25. Wang,J.H., Zhong,X.P., Zhang,Y.F., Wu,X.L., Li,S.H., Jian,P.E., Ling,Y.H., Shi,M., Chen,M.S., Wei,W. and Guo,R.P.
    Cezanne predicts progression and adjuvant TACE response in hepatocellular carcinoma
    Cell Death Dis8, e3043-e3043. PubMed  Europe PubMed DOI
2016
26. Mevissen,T.E.T., Kulathu,Y., Mulder,M.P.C., Geurink,P.P., Maslen,S.L., Gersch,M., Elliott,P.R., Burke,J.E., van Tol,B.D.M., Akutsu,M., Oualid,F.E., Kawasaki,M., Freund,S.M.V., Ovaa,H. and Komander,D.
    Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne
    Nature538, 402-405. PubMed  Europe PubMed DOI
2015
27. Moniz,S., Bandarra,D., Biddlestone,J., Campbell,K.J., Komander,D., Bremm,A. and Rocha,S.
    Cezanne regulates E2F1-dependent HIF2alpha expression
    J Cell Sci128, 3082-3093. PubMed  Europe PubMed DOI
2014
28. Bremm,A., Moniz,S., Mader,J., Rocha,S. and Komander,D.
    Cezanne (OTUD7B) regulates HIF-1alpha homeostasis in a proteasome-independent manner
    EMBO Rep15, 1268-1277. PubMed  Europe PubMed DOI
2011
29. McNally,R.S., Davis,B.K., Clements,C.M., Accavitti-Loper,M.A., Mak,T.W. and Ting,J.P.
    DJ-1 enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB
    J Biol Chem286, 4098-4106. PubMed  Europe PubMed DOI
2010
30. Bremm,A., Freund,S.M. and Komander,D.
    Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne
    Nat Struct Mol Biol17, 939-947. PubMed  Europe PubMed DOI  P
2009
31. Tse,W.K., Eisenhaber,B., Ho,S.H., Ng,Q., Eisenhaber,F. and Jiang,Y.J.
    Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development
    BMC Genomics10, 637-637. PubMed  Europe PubMed DOI
2005
32. Bermudez Moretti,M., Perullini,A.M., Batlle,A. and Correa Garcia,S.
    Expression of the UGA4 gene encoding the delta-aminolevulinic and gamma-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems
    Arch Microbiol184, 137-140. PubMed  Europe PubMed DOI
2003
33. [YEAR:7-4-2003]Evans,P.C., Smith,T.S., Lai,M.J., Williams,M.G., Burke,D.F., Heyninck,K., Kreike,M.M., Beyaert,R., Blundell,T.L. and Kilshaw,P.J.
    A novel type of deubiquitinating enzyme
    J Biol Chem278, 23180-23186. PubMed  Europe PubMed DOI
2001
34. [YEAR:1-8-2001]Evans,P.C., Taylor,E.R., Coadwell,J., Heyninck,K., Beyaert,R. and Kilshaw,P.J.
    Isolation and characterization of two novel A20-like proteins
    Biochem J357, 617-623. PubMed  Europe PubMed DOI