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Literature for peptidase C57.001: vaccinia virus I7L processing peptidase

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

(Topics flags: A Assay, I Inhibitor, P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Byrd,C.M. and Hruby,D.E.
    Editorial Expression of Concern: Development of an in vitro cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity
    Virol J (2025) 22, 296-296. PubMed  Europe PubMed DOI  PMC  EPMC
  2. Gao,Y., Xie,X., Zhang,X., Cao,J., Lan,W., You,T., Li,D., Dong,X., Dai,W., Xiang,Y., Hu,S., Shang,W., Wu,B., Zhang,Y., Xu,J., Liu,X., Wang,H., Hu,W., Zhang,M., Duan,Y., Cui,W., Zhou,H., Mao,S., Jia,H., Sun,Z., Jia,M., Yin,Y., Nguyen,H.C., Yang,K., Yang,B., Yang,X., Ji,X., Xiao,G., Wang,W., Zhang,L., Rao,Z., Liu,H. and Yang,H.
    Substrate recognition and cleavage mechanism of the monkeypox protease, Core protease
    Nature (2025) PubMed  Europe PubMed DOI
    3. 2023
  3. Arasu,M.V., Vijayaragavan,P., Purushothaman,S., Rathi,M.A., Al-Dhabi,N.A., Gopalakrishnan,V.K., Choi,K.C. and Ilavenil,S.
    Molecular docking of monkeypox (mpox) virus proteinase with FDA approved lead molecules
    J Infect Public Health (2023) 16, 784-791. PubMed  Europe PubMed DOI  PMC  EPMC
  4. Dodaro,A., Pavan,M. and Moro,S.
    Targeting the I7L Protease: A Rational Design for Anti-Monkeypox Drugs?
    Int J Mol Sci (2023) 24 PubMed  Europe PubMed DOI  PMC  EPMC
    5. 2017
  5. Wang,H., Jiang,J., Ding,R., Wang,X., Liao,M., Shao,J., Luo,X., Luo,S. and Duan,C.
    Identification and characterization of Orf virus 050 protein proteolysis
    Virus Genes (2017) 53, 400-409. PubMed  Europe PubMed DOI
    6. 2015
  6. Chen,J.S., Li,H.C., Lin,S.I., Yang,C.H., Chien,W.Y., Syu,C.L. and Lo,S.Y.
    Cleavage of Dicer protein by I7 protease during vaccinia virus infection
    PLoS ONE (2015) 10, e0120390-e0120390. PubMed  Europe PubMed DOI  PMC  EPMC
    7. 2012
  7. Aleshin,A.E., Drag,M., Gombosuren,N., Wei,G., Mikolajczyk,J., Satterthwait,A.C., Strongin,A.Y., Liddington,R.C. and Salvesen,G.S.
    Activity, specificity, and probe design for the smallpox virus protease K7L
    J Biol Chem (2012) 287, 39470-39479. PubMed  Europe PubMed DOI  P
  8. Byrd,C.M., Bolken,T.C. and Hruby,D.E.
    Vaccinia virus cysteine proteinase
    [ISSN:978-0-12-407743-0] (2012) 3, 2390-2392. DOI
    9. 2009
  9. Bisht,H., Weisberg,A.S., Szajner,P. and Moss,B.
    Assembly and disassembly of the capsid-like external scaffold of immature virions during vaccinia virus morphogenesis
    J Virol (2009) 83, 9140-9150. PubMed  Europe PubMed DOI  PMC  EPMC
    10. 2007
  10. Katritch,V., Byrd,C.M., Tseitin,V., Dai,D., Raush,E., Totrov,M., Abagyan,R., Jordan,R. and Hruby,D.E.
    Discovery of small molecule inhibitors of ubiquitin-like poxvirus proteinase I7L using homology modeling and covalent docking approaches
    J Comput Aided Mol Des (2007) 21, 549-558. PubMed  Europe PubMed DOI  I
  11. Yang,S.J. and Hruby,D.E.
    Vaccinia virus A12L protein and its AG/A proteolysis play an important role in viral morphogenic transition
    Virol J (2007) 4, 73-73. PubMed  Europe PubMed DOI  PMC  EPMC
  12. Yang,S.J.
    Characterization of vaccinia virus A12L protein proteolysis and its participation in virus assembly
    Virol J (2007) 4, 78-78. PubMed  Europe PubMed DOI  PMC  EPMC
    13. 2006
  13. Byrd,C.M. and Hruby,D.E.
    Vaccinia virus proteolysis - a review
    Rev Med Virol (2006) 16, 187-202. PubMed  Europe PubMed DOI  V
  14. Moerdyk,M.J., Byrd,C.M. and Hruby,D.E.
    Analysis of vaccinia virus temperature-sensitive I7L mutants reveals two potential functional domains
    Virol J (2006) 3, 64-64. PubMed  Europe PubMed DOI  PMC  EPMC
    15. 2005
  15. [YEAR:16-8-2005]Byrd,C.M. and Hruby,D.E.
    Development of an in vitro cleavage assay system to examine vaccinia virus I7L cysteine proteinase activity
    Virol J (16-8-2005) 2, 63-63. PubMed  Europe PubMed DOI  PMC  EPMC  A
    16. 2004
  16. Ansarah-Sobrinho,C. and Moss,B.
    Role of the I7 protein in proteolytic processing of vaccinia virus membrane and core components
    J Virol (2004) 78, 6335-6343. PubMed  Europe PubMed DOI  PMC  EPMC
  17. Byrd,C.M., Bolken,T.C. and Hruby,D.E.
    Vaccinia virus cysteine proteinase
    [ISSN:0-12-079610-4] (2004) 2, 1348-1350.  V
  18. Byrd,C.M., Bolken,T.C., Mjalli,A.M., Arimilli,M.N., Andrews,R.C., Rothlein,R., Andrea,T., Rao,M., Owens,K.L. and Hruby,D.E.
    New class of orthopoxvirus antiviral drugs that block viral maturation
    J Virol (2004) 78, 12147-12156. PubMed  Europe PubMed DOI  PMC  EPMC  I
    19. 2003
  19. Byrd,C.M., Bolken,T.C. and Hruby,D.E.
    Molecular dissection of the vaccinia virus I7L core protein proteinase
    J Virol (2003) 77, 11279-11283. PubMed  Europe PubMed DOI  PMC  EPMC
    20. 2002
  20. Byrd,C.M., Bolken,T.C. and Hruby,D.E.
    The vaccinia virus I7L gene product is the core protein proteinase
    J Virol (2002) 76, 8973-8976. PubMed  Europe PubMed DOI  PMC  EPMC
    21. 1995
  21. Ericsson,M., Cudmore,S., Shuman,S., Condit,R.C., Griffiths,G. and Locker,J.K.
    Characterization of ts 16, a temperature-sensitive mutant of vaccinia virus
    J Virol (1995) 69, 7072-7086. PubMed  Europe PubMed  PMC  EPMC
    22. 1994
  22. [YEAR:18-3-1994]Lee,P. and Hruby,D.E.
    Proteolytic cleavage of vaccinia virus virion proteins. Mutational analysis of the specificity determinants
    J Biol Chem (18-3-1994) 269, 8616-8622. PubMed  Europe PubMed
    23. 1993
  23. Kane,E.M. and Shuman,S.
    Vaccinia virus morphogenesis is blocked by a temperature-sensitive mutation in the I7 gene that encodes a virion component
    J Virol (1993) 67, 2689-2698. PubMed  Europe PubMed  PMC  EPMC
  24. Lee,P. and Hruby,D.E.
    Trans processing of vaccinia virus core proteins
    J Virol (1993) 67, 4252-4263. PubMed  Europe PubMed  PMC  EPMC
    25. 1991
  25. VanSlyke,J.K., Franke,C.A. and Hruby,D.E.
    Proteolytic maturation of vaccinia virus core proteins: identification of a conserved motif at the N termini of the 4b and 25K virion proteins
    J Gen Virol (1991) 72, 411-416. PubMed  Europe PubMed
  26. VanSlyke,J.K., Whitehead,S.S., Wilson,E.M. and Hruby,D.E.
    The multistep proteolytic maturation pathway utilized by vaccinia virus P4a protein: a degenerate conserved cleavage motif within core proteins
    Virology (1991) 183, 467-478. PubMed  Europe PubMed DOI
    27. 1973
  27. [YEAR:5-12-1973]Moss,B. and Rosenblum,E.N.
    Letter: Protein cleavage and poxvirus morphogenesis: tryptic peptide analysis of core precursors accumulated by blocking assembly with rifampicin
    J Mol Biol (5-12-1973) 81, 267-269. PubMed  Europe PubMed

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