Literature for family C51 unassigned peptidases

Summary Sequences Sequence features Distribution Literature

(Topics flags: S Structure, A Assay, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Alreja,A.B., Appel,A.E., Zhu,J.C., Riley,S.P., Gonzalez-Juarbe,N. and Nelson,D.C.
    SP-CHAP, an endolysin with enhanced activity against biofilm pneumococci and nasopharyngeal colonization
    MBio15, e0006924-e0006924. PubMed  Europe PubMed DOI
  2. 2023
  3. Krishnappa,G., Mandal,M., Ganesan,S., Babu,S., Padavattan,S., Haradara Bahubali,V.K. and Padmanabhan,B.
    Structural and biochemical insights into the bacteriophage PlyGRCS endolysin targeting methicillin-resistant Staphylococcus aureus (MRSA) and serendipitous discovery of its interaction with a cold shock protein C (CspC)
    Protein Sci32, e4737-e4737. PubMed  Europe PubMed DOI
  4. 2021
  5. Li,X., Wang,S., Nyaruaba,R., Liu,H., Yang,H. and Wei,H.
    A Highly Active Chimeric Lysin with a Calcium-Enhanced Bactericidal Activity against Staphylococcus aureus In Vitro and In Vivo
    Antibiotics (Basel)10, PubMed  Europe PubMed DOI
  6. Oechslin,F., Menzi,C., Moreillon,P. and Resch,G.
    The multi-domain architecture of a bacteriophage endolysin enables intramolecular synergism and regulation of bacterial lysis
    J Biol Chem100639-100639. PubMed  Europe PubMed DOI
  7. 2020
  8. Willing,S., Dyer,E., Schneewind,O. and Missiakas,D.
    FmhA and FmhC of Staphylococcus aureus incorporate serine residues into peptidoglycan crossbridges
    J Biol Chem295, 13664-13676. PubMed  Europe PubMed DOI
  9. Yang,H., Luo,D., Etobayeva,I., Li,X., Gong,Y., Wang,S., Li,Q., Xu,P., Yin,W., He,J., Nelson,D.C. and Wei,H.
    Linker editing of pneumococcal lysin ClyJ conveys improved bactericidal activity
    Antimicrob Agents Chemother64, e01610-19-e01610-19. PubMed  Europe PubMed DOI
  10. 2019
  11. Yang,H., Gong,Y., Zhang,H., Etobayeva,I., Miernikiewicz,P., Luo,D., Li,X., Zhang,X., Dabrowska,K., Nelson,D.C., He,J. and Wei,H.
    ClyJ, a novel pneumococcal chimeric lysin with a CHAP catalytic domain
    Antimicrob Agents Chemother63, e02043-18-e02043-18. PubMed  Europe PubMed DOI
  12. 2018
  13. Fujiki,J., Nakamura,T., Furusawa,T., Ohno,H., Takahashi,H., Kitana,J., Usui,M., Higuchi,H., Tanji,Y., Tamura,Y. and Iwano,H.
    Characterization of the lytic capability of a LysK-like endolysin, Lys-phiSA012, derived from a polyvalent Staphylococcus aureus bacteriophage
    Pharmaceuticals (Basel)11, PubMed  Europe PubMed DOI
  14. 2017
  15. Cheng,M., Zhang,Y., Li,X., Liang,J., Hu,L., Gong,P., Zhang,L., Cai,R., Zhang,H., Ge,J., Ji,Y., Guo,Z., Feng,X., Sun,C., Yang,Y., Lei,L., Han,W. and Gu,J.
    Endolysin LysEF-P10 shows potential as an alternative treatment strategy for multidrug-resistant Enterococcus faecalis infections
    Sci Rep7, 10164-10164. PubMed  Europe PubMed DOI
  16. Haddad Kashani,H., Fahimi,H., Dasteh Goli,Y. and Moniri,R.
    A novel chimeric endolysin with antibacterial activity against methicillin-resistant Staphylococcus aureus
    Front Cell Infect Microbiol7, 290-290. PubMed  Europe PubMed DOI
  17. Kohler,V., Probst,I., Aufschnaiter,A., Buttner,S., Schaden,L., Rechberger,G.N., Koraimann,G., Grohmann,E. and Keller,W.
    Conjugative type IV secretion in Gram-positive pathogens: TraG, a lytic transglycosylase and endopeptidase, interacts with translocation channel protein TraM
    Plasmid91, 9-18. PubMed  Europe PubMed DOI
  18. Lood,R., Molina,H. and Fischetti,V.A.
    Determining bacteriophage endopeptidase activity using either fluorophore-quencher labeled peptides combined with liquid chromatography-mass spectrometry (LC-MS) or Forster resonance energy transfer (FRET) assays
    PLoS ONE12, e0173919-e0173919. PubMed  Europe PubMed DOI  A
  19. 2016
  20. Hu,Y., Yang,H., Wang,J., Zhang,Y., Yu,J. and Wei,H.
    Comparison between a chimeric lysin ClyH and other enzymes for extracting DNA to detect methicillin resistant Staphylococcus aureus by quantitative PCR
    World J Microbiol Biotechnol32, 1-1. PubMed  Europe PubMed DOI
  21. 2015
  22. Becker,S.C., Swift,S., Korobova,O., Schischkova,N., Kopylov,P., Donovan,D.M. and Abaev,I.
    Lytic activity of the staphylolytic Twort phage endolysin CHAP domain is enhanced by the SH3b cell wall binding domain
    FEMS Microbiol Lett362, 1-8. PubMed  Europe PubMed DOI
  23. Dong,Q., Wang,J., Yang,H., Wei,C., Yu,J., Zhang,Y., Huang,Y., Zhang,X.-E. and Wei,H.
    Construction of a chimeric lysin Ply187N-V12C with extended lytic activity against staphylococci and streptococci
    Microb Biotechnol8, 210-220. PubMed  Europe PubMed DOI
  24. Huang,Y., Yang,H., Yu,J. and Wei,H.
    Molecular dissection of phage lysin PlySs2: integrity of the catalytic and cell wall binding domains is essential for its broad lytic activity
    Virol Sin30, 45-51. PubMed  Europe PubMed DOI
  25. Li,Q., Cheng,W., Morlot,C., Bai,X.-H., Jiang,Y.-L., Wang,W., Roper,D.I., Vernet,T., Dong,Y.-H., Chen,Y. and Zhou,C.-Z.
    Full-length structure of the major autolysin LytA
    Acta Crystallogr Sect D Biol Crystallogr71, 1373-1381. PubMed  Europe PubMed DOI  S
  26. Linden,S.B., Zhang,H., Heselpoth,R.D., Shen,Y., Schmelcher,M., Eichenseher,F. and Nelson,D.C.
    Biochemical and biophysical characterization of PlyGRCS, a bacteriophage endolysin active against methicillin-resistant Staphylococcus aureus
    Appl Microbiol Biotechnol99, 741-752. PubMed  Europe PubMed DOI
  27. 2014
  28. Lood,R., Raz,A., Molina,H., Euler,C.W. and Fischetti,V.A.
    A highly active and negatively charged Streptococcus pyogenes lysin with a rare D-alanyl-L-alanine endopeptidase activity protects mice against streptococcal bacteremia
    Antimicrob Agents Chemother58, 3073-3084. PubMed  Europe PubMed DOI
  29. Sundarrajan,S., Raghupatil,J., Vipra,A., Narasimhaswamy,N., Saravanan,S., Appaiah,C., Poonacha,N., Desai,S., Nair,S., Bhatt,R.N., Roy,P., Chikkamadaiah,R., Durgaiah,M., Sriram,B., Padmanabhan,S. and Sharma,U.
    Bacteriophage-derived CHAP domain protein, P128, kills Staphylococcus cells by cleaving interpeptide cross-bridge of peptidoglycan
    Microbiology (Reading)160, 2157-2169. PubMed  Europe PubMed DOI
  30. 2013
  31. Arends,K., Celik,E.K., Probst,I., Goessweiner-Mohr,N., Fercher,C., Grumet,L., Soellue,C., Abajy,M.Y., Sakinc,T., Broszat,M., Schiwon,K., Koraimann,G., Keller,W. and Grohmann,E.
    TraG encoded by the pIP501 type IV secretion system is a two-domain peptidoglycan-degrading enzyme essential for conjugative transfer
    J Bacteriol195, 4436-4444. PubMed  Europe PubMed DOI
  32. Gilmer,D.B., Schmitz,J.E., Euler,C.W. and Fischetti,V.A.
    Novel bacteriophage lysin with broad lytic activity protects against mixed infection by Streptococcus pyogenes and methicillin-resistant staphylococcus aureus
    Antimicrob Agents Chemother57, 2743-2750. PubMed  Europe PubMed DOI
  33. Mao,J., Schmelcher,M., Harty,W.J., Foster-Frey,J. and Donovan,D.M.
    Chimeric Ply187 endolysin kills Staphylococcus aureus more effectively than the parental enzyme
    FEMS Microbiol Lett342, 30-36. PubMed  Europe PubMed DOI
  34. 2012
  35. George,S.E., Chikkamadaiah,R., Durgaiah,M., Joshi,A.A., Thankappan,U.P., Madhusudhana,S.N. and Sriram,B.
    Biochemical characterization and evaluation of cytotoxicity of antistaphylococcal chimeric protein P128
    BMC Res Notes5, 280-280. PubMed  Europe PubMed DOI  U
  36. Schmelcher,M., Korobova,O., Schischkova,N., Kiseleva,N., Kopylov,P., Pryamchuk,S., Donovan,D.M. and Abaev,I.
    Staphylococcus haemolyticus prophage PhiSH2 endolysin relies on cysteine, histidine-dependent amidohydrolases/peptidases activity for lysis 'from without'
    J Biotechnol162, 289-298. PubMed  Europe PubMed DOI
  37. 2010
  38. Daniel,A., Euler,C., Collin,M., Chahales,P., Gorelick,K.J. and Fischetti,V.A.
    Synergism between a novel chimeric lysin and oxacillin protects against infection by methicillin-resistant Staphylococcus aureus
    Antimicrob Agents Chemother54, 1603-1612. PubMed  Europe PubMed DOI
  39. 2004
  40. Romero,P., Lopez,R. and Garcia,E.
    Characterization of LytA-like N-acetylmuramoyl-L-alanine amidases from two new Streptococcus mitis bacteriophages provides insights into the properties of the major pneumococcal autolysin
    J Bacteriol186, 8229-8239. PubMed  Europe PubMed DOI