Literature for peptidase C48.009: SENP7 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, M Mutation, P Specificity, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Saad,A.K., Hassan,N.H., Soliman,H.N., Zaki,M.S., Senousy,S.M. and El-Dessouky,S.H.
    Lethal Phenotype and Expansion of the Clinical Spectrum of Biallelic Loss of Function Variant in SENP7 Gene Unveiled by Whole Exome Sequencing
    Clin Genet PubMed  Europe PubMed DOI
  2. 2024
  3. Pei,J., Zou,D., Li,L., Kang,L., Sun,M., Li,X., Chen,Q., Chen,D., Qu,B., Gao,X. and Lin,Z.
    Senp7 Deficiency Impairs Lipid Droplets Maturation in White Adipose Tissues via Plin4 DeSUMOylation
    J Biol Chem107319-107319. PubMed  Europe PubMed DOI
  4. 2023
  5. Samra,N., Jansen,N.S., Morani,I., Kakun,R.R., Zaid,R., Paperna,T., Garcia-Dominguez,M., Viner,Y., Frankenthal,H., Shinwell,E.S., Portnov,I., Bakry,D., Shalata,A., Shapira Rootman,M., Kidron,D., Claessens,L.A., Wevers,R.A., Mandel,H., Vertegaal,A.C.O. and Weiss,K.
    Exome sequencing links the SUMO protease SENP7 with fatal arthrogryposis multiplex congenita, early respiratory failure and neutropenia
    J Med Genet60, 1133-1141. PubMed  Europe PubMed DOI
  6. 2022
  7. Amrute-Nayak,M., Gand,L.V., Khan,B., Holler,T., Kefalakes,E., Kosanke,M., Kraft,T. and Nayak,A.
    SENP7 deSUMOylase-governed transcriptional program coordinates sarcomere assembly and is targeted in muscle atrophy
    Cell Rep41, 111702-111702. PubMed  Europe PubMed DOI
  8. Li,Y., De Bolos,A., Amador,V. and Reverter,D.
    Structural Basis for the SUMO2 Isoform Specificity of SENP7
    J Mol Biol434, 167875-167875. PubMed  Europe PubMed DOI
  9. Wu,Z., Huang,H., Han,Q., Hu,Z., Teng,X.L., Ding,R., Ye,Y., Yu,X., Zhao,R., Wang,Z. and Zou,Q.
    SENP7 senses oxidative stress to sustain metabolic fitness and antitumor functions of CD8+ T cells
    J Clin Invest132, PubMed  Europe PubMed DOI
  10. 2020
  11. Colnaghi,L., Conz,A., Russo,L., Musi,C.A., Fioriti,L., Borsello,T. and Salmona,M.
    Neuronal Localization of SENP Proteins with Super Resolution Microscopy
    Brain Sci10, PubMed  Europe PubMed DOI
  12. 2017
  13. Karami,S., Lin,F.M., Kumar,S., Bahnassy,S., Thangavel,H., Quttina,M., Li,Y., Ren,J. and Bawa-Khalfe,T.
    Novel SUMO-protease SENP7S regulates beta-catenin signaling and mammary epithelial cell transformation
    Sci Rep7, 46477-46477. PubMed  Europe PubMed DOI
  14. 2016
  15. Juarez-Vicente,F., Luna-Pelaez,N. and Garcia-Dominguez,M.
    The Sumo protease Senp7 is required for proper neuronal differentiation
    Biochim Biophys Acta1863, 1490-1498. PubMed  Europe PubMed DOI
  16. 2015
  17. Romeo,K., Louault,Y., Cantaloube,S., Loiodice,I., Almouzni,G. and Quivy,J.P.
    The SENP7 SUMO-protease presents a module of two HP1 interaction motifs that locks HP1 protein at pericentric heterochromatin
    Cell Rep10, 771-782. PubMed  Europe PubMed DOI
  18. 2013
  19. Garvin,A.J., Densham,R.M., Blair-Reid,S.A., Pratt,K.M., Stone,H.R., Weekes,D., Lawrence,K.J. and Morris,J.R.
    The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair
    EMBO Rep14, 975-983. PubMed  Europe PubMed DOI
  20. 2012
  21. Bawa-Khalfe,T., Lu,L.S., Zuo,Y., Huang,C., Dere,R., Lin,F.M. and Yeh,E.T.
    Differential expression of SUMO-specific protease 7 variants regulates epithelial-mesenchymal transition
    Proc Natl Acad Sci U S A109, 17466-17471. PubMed  Europe PubMed DOI  M
  22. Maison,C., Romeo,K., Bailly,D., Dubarry,M., Quivy,J.P. and Almouzni,G.
    The SUMO protease SENP7 is a critical component to ensure HP1 enrichment at pericentric heterochromatin
    Nat Struct Mol Biol19, 458-460. PubMed  Europe PubMed DOI
  23. Reverter,D.
    SENP6 and SENP7 peptidases
    [ISSN:978-0-12-407743-0]3, 2375-2379. DOI
  24. 2011
  25. Albrow,V.E., Ponder,E.L., Fasci,D., Bekes,M., Deu,E., Salvesen,G.S. and Bogyo,M.
    Development of small molecule inhibitors and probes of human SUMO deconjugating proteases
    Chem Biol18, 722-732. PubMed  Europe PubMed DOI  I
  26. Alegre,K.O. and Reverter,D.
    Swapping small ubiquitin-like modifier (SUMO) isoform specificity of SUMO proteases SENP6 and SENP7
    J Biol Chem286, 36142-36151. PubMed  Europe PubMed DOI
  27. 2009
  28. Shen,L.N., Geoffroy,M.C., Jaffray,E.G. and Hay,R.T.
    Characterization of SENP7, a SUMO-2/3-specific isopeptidase
    Biochem J421, 223-230. PubMed  Europe PubMed DOI
  29. Wang,Y., Mukhopadhyay,D., Mathew,S., Hasebe,T., Heimeier,R.A., Azuma,Y., Kolli,N., Shi,Y.B., Wilkinson,K.D. and Dasso,M.
    Identification and developmental expression of Xenopus laevis SUMO proteases
    PLoS ONE4, e8462-e8462. PubMed  Europe PubMed DOI
  30. 2008
  31. Drag,M., Mikolajczyk,J., Krishnakumar,I.M., Huang,Z. and Salvesen,G.S.
    Activity profiling of human deSUMOylating enzymes (SENPs) with synthetic substrates suggests an unexpected specificity of two newly characterized members of the family
    Biochem J409, 461-469. PubMed  Europe PubMed DOI  P
  32. Lima,C.D. and Reverter,D.
    Structure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7
    J Biol Chem283, 32045-32055. PubMed  Europe PubMed DOI  S
  33. 2007
  34. Mikolajczyk,J., Drag,M., Bekes,M., Cao,J.T., Ronai,Z. and Salvesen,G.S.
    Small Ubiquitin-related Modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs
    J Biol Chem282, 26217-26224. PubMed  Europe PubMed DOI  P
  35. 2000
  36. Yeh,E.T., Gong,L. and Kamitani,T.
    Ubiquitin-like proteins: new wines in new bottles
    Gene248, 1-14. PubMed  Europe PubMed DOI