Literature for peptidase homologue C19.972: ubiquitin-specific endopeptidase 39 [misleading]

(Topics flags: S Structure, M Mutation, K Knockout. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Cheng,S., Qiu,Z., Zhang,Z., Li,Y., Zhu,Y., Zhou,Y., Yang,Y., Zhang,Y., Yang,D., Zhang,Y., Liu,H., Dai,Z., Sun,S.L. and Liu,S.
   USP39 phase separates into the nucleolus and drives lung adenocarcinoma progression by promoting GLI1 expression
   Cell Commun Signal23, 56-56. PubMed  Europe PubMed DOI  K
2. Shen,S., Xue,G., Zeng,Z., Peng,L., Nie,W. and Zeng,X.
   Toosendanin promotes prostate cancer cell apoptosis, ferroptosis and M1 polarization via USP39-mediated PLK1 deubiquitination
   Naunyn Schmiedebergs Arch Pharmacol PubMed  Europe PubMed DOI  K
3. Wang,X., Zhang,P., Xie,J. and Zuo,X.
   USP39 promotes retinal pathological angiogenesis in retinopathy of prematurity by stabilizing SIRT2 expression through deubiquitination
   Int Ophthalmol45, 39-39. PubMed  Europe PubMed DOI
2024
4. Becirovic,T., Zhang,B., Vakifahmetoglu-Norberg,H., Kaminskyy,V.O., Kochetkova,E. and Norberg,E.
   USP39 regulates pyruvate handling in non-small cell lung cancer
   Cell Death Discov10, 502-502. PubMed  Europe PubMed DOI
5. Hu,Y., Wang,Y., Hu,W., Hu,C., Wang,B., Liu,C., Deng,A., Shen,B., Wu,K. and Liu,Y.
   USP39 Promotes the Viability and Migration of Head and Neck Squamous Cell Carcinoma Cell by Regulating STAT1
   Technol Cancer Res Treat23, 15330338241250298-15330338241250298. PubMed  Europe PubMed DOI  K
6. Lu,C., Cai,Y., Wu,S., Wang,Y., Li,J.B., Xu,G. and Ma,J.
   Deubiquitinating enzyme USP39 promotes the growth and metastasis of gastric cancer cells by modulating the degradation of RNA-binding protein RBM39
   J Biol Chem107751-107751. PubMed  Europe PubMed DOI  K
7. Prieto-Garcia,C., Matkovic,V., Mosler,T., Li,C., Liang,J., Oo,J.A., Haidle,F., Macinkovic,I., Cabrera-Orefice,A., Berkane,R., Giuliani,G., Xu,F., Jacomin,A.C., Tomaskovic,I., Basoglu,M., Hoffmann,M.E., Rathore,R., Cetin,R., Boutguetait,D., Bozkurt,S., Hernandez Canas,M.C., Keller,M., Busam,J., Shah,V.J., Wittig,I., Kaulich,M., Beli,P., Galej,W.P., Ebersberger,I., Wang,L., Munch,C., Stolz,A., Brandes,R.P., Tse,W.K.F., Eimer,S., Stainier,D.Y.R., Legewie,S., Zarnack,K., Muller-McNicoll,M. and Dikic,I.
   Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy
   Science386, 768-776. PubMed  Europe PubMed DOI
8. Sirera,J., Sarlak,S., Teisseire,M., Carminati,A., Nicolini,V.J., Savy,C., Brest,P., Juel,T., Bontoux,C., Deckert,M., Ohanna,M., Giuliano,S., Dufies,M., Pages,G. and Luciano,F.
   Disrupting USP39 deubiquitinase function impairs the survival and migration of multiple myeloma cells through ZEB1 degradation
   J Exp Clin Cancer Res43, 335-335. PubMed  Europe PubMed DOI  K
2023
9. Choi,Y., Lee,Y., Kim,J.S., Zhang,P. and Kim,J.
   USP39-Mediated Non-Proteolytic Control of ETS2 Suppresses Nuclear Localization and Activity
   Biomolecules13, PubMed  Europe PubMed DOI
10. Wang,J., Wang,X., Cao,M., Zhang,L. and Lin,J.
    CircUSP39/miR-362-3p/TRAF3 Axis Mediates Hypoxia/Reoxygenation-Induced Cardiomyocyte Oxidative Stress, Inflammation, and Apoptosis
    Int Heart J64, 263-273. PubMed  Europe PubMed DOI
11. Wang,W., Lei,Y., Zhang,G., Li,X., Yuan,J., Li,T., Zhong,W., Zhang,Y., Tan,X. and Song,G.
    USP39 stabilizes beta-catenin by deubiquitination and suppressing E3 ligase TRIM26 pre-mRNA maturation to promote HCC progression
    Cell Death Dis14, 63-63. PubMed  Europe PubMed DOI
12. Xiao,Y., Chen,X., Hu,W., Ma,W., Di,Q., Tang,H., Zhao,X., Huang,G. and Chen,W.
    USP39-mediated deubiquitination of Cyclin B1 promotes tumor cell proliferation and glioma progression
    Transl Oncol34, 101713-101713. PubMed  Europe PubMed DOI  K
13. Yu,J., Yuan,S., Song,J. and Yu,S.
    USP39 interacts with SIRT7 to promote cervical squamous cell carcinoma by modulating autophagy and oxidative stress via FOXM1
    J Transl Med21, 807-807. PubMed  Europe PubMed DOI  K
14. Zheng,J., Wu,S., Tang,M., Xi,S., Wang,Y., Ren,J., Luo,H., Hu,P., Sun,L., Du,Y., Yang,H., Wang,F., Gao,H., Dai,Z., Ou,X. and Li,Y.
    USP39 promotes hepatocellular carcinogenesis through regulating alternative splicing in cooperation with SRSF6/HNRNPC
    Cell Death Dis14, 670-670. PubMed  Europe PubMed DOI
2022
15. Cui,F., Luo,P., Wu,R. and Meng,J.
    miR-381 Inhibits Proliferation and Invasion of Non-Small-Cell Cancer Cells by Targeting USP39
    Dis Markers2022, 2195393-2195393. PubMed  Europe PubMed DOI
16. Kimura-Yoshida,C., Mochida,K., Kanno,S.I. and Matsuo,I.
    USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components
    Commun Biol5, 378-378. PubMed  Europe PubMed DOI
17. Liu,Y., Wu,Q., Sun,T., Huang,J., Han,G. and Han,H.
    DNAAF5 promotes hepatocellular carcinoma malignant progression by recruiting USP39 to improve PFKL protein stability
    Front Oncol12, 1032579-1032579. PubMed  Europe PubMed DOI  K
18. Ruan,G.X., Li,Y., Chen,W., Huang,H., Zhang,R., Chen,C., Lam,K.P., Xu,S. and Ou,X.
    The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement
    Cell Rep38, 110338-110338. PubMed  Europe PubMed DOI
19. Xiao,Y., Ma,W., Hu,W., Di,Q., Zhao,X., Ma,X., Chen,X., Sun,P., Wu,H., Wu,Z. and Chen,W.
    Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation
    Mol Oncol16, 388-404. PubMed  Europe PubMed DOI
20. Zhang,Z., Liu,W., Bao,X., Sun,T., Wang,J., Li,M. and Liu,C.
    USP39 facilitates breast cancer cell proliferation through stabilization of FOXM1
    Am J Cancer Res12, 3644-3661. PubMed  Europe PubMed  K
2021
21. Dong,X., Liu,Z., Zhang,E., Zhang,P., Wang,Y., Hang,J. and Li,Q.
    USP39 promotes tumorigenesis by stabilizing and deubiquitinating SP1 protein in hepatocellular carcinoma
    Cell Signal85, 110068-110068. PubMed  Europe PubMed DOI
22. Kim,J.J., Lee,S.Y., Hwang,Y., Kim,S., Chung,J.M., Park,S., Yoon,J., Yun,H., Ji,J.H., Chae,S., Cho,H., Kim,C.G., Dawson,T.M., Kim,H., Dawson,V.L. and Kang,H.C.
    USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing
    Nucleic Acids Res49, 11083-11102. PubMed  Europe PubMed DOI
23. Li,X., Yuan,J., Song,C., Lei,Y., Xu,J., Zhang,G., Wang,W. and Song,G.
    Deubiquitinase USP39 and E3 ligase TRIM26 balance the level of ZEB1 ubiquitination and thereby determine the progression of hepatocellular carcinoma
    Cell Death Differ PubMed  Europe PubMed DOI
24. Pan,X.W., Xu,D., Chen,W.J., Chen,J.X., Chen,W.J., Ye,J.Q., Gan,S.S., Zhou,W., Song,X., Shi,L. and Cui,X.G.
    USP39 promotes malignant proliferation and angiogenesis of renal cell carcinoma by inhibiting VEGF-A165b alternative splicing via regulating SRSF1 and SRPK1
    Cancer Cell Int21, 486-486. PubMed  Europe PubMed DOI  K
25. Yuan,J., Li,X., Zhang,G., Cheng,W., Wang,W., Lei,Y., Ma,Q. and Song,G.
    USP39 mediates p21-dependent proliferation and neoplasia of colon cancer cells by regulating the p53/p21/CDC2/cyclin B1 axis
    Mol Carcinog60, 265-278. PubMed  Europe PubMed DOI  K
26. Zhao,Y., Geng,H., Liu,G., Ji,Q., Cheng,X., Li,X., Liu,W., Thorne,R.F., Zhang,R. and Liu,X.
    The Deubiquitinase USP39 Promotes ESCC Tumorigenesis Through Pre-mRNA Splicing of the mTORC2 Component Rictor
    Front Oncol11, 667495-667495. PubMed  Europe PubMed DOI
2020
27. Dong,L., Yu,L., Li,H., Shi,L., Luo,Z., Zhao,H., Liu,Z., Yin,G., Yan,X. and Lin,Z.
    An NAD(+)-Dependent Deacetylase SIRT7 Promotes HCC Development Through Deacetylation of USP39
    iScience23, 101351-101351. PubMed  Europe PubMed DOI
28. Peng,Y., Guo,J., Sun,T., Fu,Y., Zheng,H., Dong,C. and Xiong,S.
    USP39 Serves as a Deubiquitinase to Stabilize STAT1 and Sustains Type I IFN-Induced Antiviral Immunity
    J Immunol PubMed  Europe PubMed DOI  K
29. Yuan,J., Zhang,G., Li,X., Ma,Q., Cheng,W., Wang,W., Zhang,B., Hu,T. and Song,G.
    Knocking down USP39 Inhibits the Growth and Metastasis of Non-Small-Cell Lung Cancer Cells through Activating the p53 Pathway
    Int J Mol Sci21, PubMed  Europe PubMed DOI  K
2019
30. Liu,C., Yao,X., Li,M., Xi,Y. and Zhao,L.
    USP39 regulates the cell cycle, survival, and growth of human leukemia cells
    Biosci Rep39, BSR20190040-BSR20190040. PubMed  Europe PubMed DOI
31. Wang,L., Chen,T., Li,X., Yan,W., Lou,Y., Liu,Z., Chen,H. and Cui,Z.
    USP39 promotes ovarian cancer malignant phenotypes and carboplatin chemoresistance
    Int J Oncol55, 277-288. PubMed  Europe PubMed DOI
32. Wu,J., Chen,Y., Geng,G., Li,L., Yin,P., Nowsheen,S., Li,Y., Wu,C., Liu,J., Zhao,F., Kim,W., Zhou,Q., Huang,J., Guo,G., Zhang,C., Tu,X., Gao,X., Lou,Z., Luo,K., Qiao,H. and Yuan,J.
    USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2
    Cancer Lett449, 114-124. PubMed  Europe PubMed DOI
33. Yan,C., Yuan,J., Xu,J., Zhang,G., Li,X., Zhang,B., Hu,T., Huang,X., Mao,Y. and Song,G.
    Ubiquitin-specific peptidase 39 regulates the process of proliferation and migration of human ovarian cancer via p53/p21 pathway and EMT
    Med Oncol36, 95-95. PubMed  Europe PubMed DOI
2018
34. Dong,X., Su,H., Jiang,F., Li,H., Shi,G. and Fan,L.
    miR-133a, directly targeted USP39, suppresses cell proliferation and predicts prognosis of gastric cancer
    Oncol Lett15, 8311-8318. PubMed  Europe PubMed DOI
35. Xing,Z., Sun,F., He,W., Wang,Z., Song,X. and Zhang,F.
    Downregulation of ubiquitin-specific peptidase 39 suppresses the proliferation and induces the apoptosis of human colorectal cancer cells
    Oncol Lett15, 5443-5450. PubMed  Europe PubMed DOI
2017
36. Cai,J., Liu,T., Huang,P., Yan,W., Guo,C., Xiong,L. and Liu,A.
    USP39, a direct target of microRNA-133a, promotes progression of pancreatic cancer via the AKT pathway
    Biochem Biophys Res Commun486, 184-190. PubMed  Europe PubMed DOI
37. Fraile,J.M., Manchado,E., Lujambio,A., Quesada,V., Campos-Iglesias,D., Webb,T.R., Lowe,S.W., Lopez-Otin,C. and Freije,J.M.
    USP39 deubiquitinase is essential for KRAS oncogene-driven cancer
    J Biol Chem292, 4164-4175. PubMed  Europe PubMed DOI
38. Gan,Z., Han,K., Lin,S., Hu,H., Shen,Z. and Min,D.
    Knockdown of ubiquitin-specific peptidase 39 inhibited the growth of osteosarcoma cells and induced apoptosis in vitro
    Biol Res50, 15-15. PubMed  Europe PubMed DOI
39. Yuan,X., Sun,X., Shi,X., Jiang,C., Yu,D., Zhang,W. and Ding,Y.
    USP39 regulates the growth of SMMC-7721 cells via FoxM1
    Exp Ther Med13, 1506-1513. PubMed  Europe PubMed DOI  K
40. Yuan,X., Sun,X., Shi,X., Wang,H., Wu,G., Jiang,C., Yu,D., Zhang,W., Xue,B. and Ding,Y.
    USP39 promotes colorectal cancer growth and metastasis through the Wnt/beta-catenin pathway
    Oncol Rep37, 2398-2404. PubMed  Europe PubMed DOI
2016
41. Li,K.Y., Zhang,J., Jiang,L.C., Zhang,B., Xia,C.P., Xu,K., Chen,H.Y., Yang,Q.Z., Liu,S.W. and Zhu,H.
    Knockdown of USP39 by lentivirus-mediated RNA interference suppresses the growth of oral squamous cell carcinoma
    Cancer Biomark16, 137-144. PubMed  Europe PubMed DOI  K
42. Zhao,Y., Zhang,B., Lei,Y., Sun,J., Zhang,Y., Yang,S. and Zhang,X.
    Knockdown of USP39 induces cell cycle arrest and apoptosis in melanoma
    Tumour Biol37, 13167-13176. PubMed  Europe PubMed DOI  K
2015
43. Pan,Z., Pan,H., Zhang,J., Yang,Y., Liu,H., Yang,Y., Huang,G., Ni,J., Huang,J. and Zhou,W.
    Lentivirus mediated silencing of ubiquitin specific peptidase 39 inhibits cell proliferation of human hepatocellular carcinoma cells in vitro
    Biol Res48, 18- PubMed  Europe PubMed DOI  K
2014
44. Hadjivassiliou,H., Rosenberg,O.S. and Guthrie,C.
    The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing
    RNA20, 656-669. PubMed  Europe PubMed DOI  S
2013
45. Wang,H., Ji,X., Liu,X., Yao,R., Chi,J., Liu,S., Wang,Y., Cao,W. and Zhou,Q.
    Lentivirus-mediated inhibition of USP39 suppresses the growth of breast cancer cells in vitro
    Oncol Rep30, 2871-2877. PubMed  Europe PubMed DOI
2011
46. Rios,Y., Melmed,S., Lin,S. and Liu,N.A.
    Zebrafish usp39 mutation leads to rb1 mRNA splicing defect and pituitary lineage expansion
    PLoS Genet7, e1001271-e1001271. PubMed  Europe PubMed DOI  M
2008
47. van Leuken,R.J., Luna-Vargas,M.P., Sixma,T.K., Wolthuis,R.M. and Medema,R.H.
    Usp39 is essential for mitotic spindle checkpoint integrity and controls mRNA-levels of aurora B
    Cell Cycle7, 2710-2719. PubMed  Europe PubMed