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Literature for peptidase C19.087: ubiquitin-specific peptidase 8 (Saccharomyces cerevisiae)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

(Topics flags: S Structure, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Li,Y., Wang,J., Huang-Fu,X., Ma,T., Sun,K., Chen,X., Jiao,C., Ma,Z., Jiang,J. and Yin,Y.
    Transcription elongation regulated by H2B deubiquitination and H2A.Z eviction enables fungal virulence
    New Phytol (2025) PubMed  Europe PubMed DOI
    2. 2023
  2. Barman,P., Chakraborty,P., Bhaumik,R. and Bhaumik,S.R.
    UPS writes a new saga of SAGA
    Biochim Biophys Acta Gene Regul Mech (2023) 1866, 194981-194981. PubMed  Europe PubMed DOI
  3. Radmall,K.S., Shukla,P.K., Leng,A.M. and Chandrasekharan,M.B.
    Structure-function analysis of histone H2B and PCNA ubiquitination dynamics using deubiquitinase-deficient strains
    bioRxiv (2023) PubMed  Europe PubMed DOI  PMC  EPMC
  4. Radmall,K.S., Shukla,P.K., Leng,A.M. and Chandrasekharan,M.B.
    Structure-function analysis of histone H2B and PCNA ubiquitination dynamics using deubiquitinase-deficient strains
    Sci Rep (2023) 13, 16731-16731. PubMed  Europe PubMed DOI  PMC  EPMC
    5. 2020
  5. Cornelio-Parra,D.V., Goswami,R., Costanzo,K., Morales-Sosa,P. and Mohan,R.D.
    Function and regulation of the Spt-Ada-Gcn5-Acetyltransferase (SAGA) deubiquitinase module
    Biochim Biophys Acta Gene Regul Mech (2020) , 194630-194630. PubMed  Europe PubMed DOI  V
  6. Nuno-Cabanes,C. and Rodriguez-Navarro,S.
    The promiscuity of the SAGA complex subunits: Multifunctional or moonlighting proteins?
    Biochim Biophys Acta Gene Regul Mech (2020) , 194607-194607. PubMed  Europe PubMed DOI  V
  7. Timmers,H.T.M.
    SAGA and TFIID: Friends of TBP drifting apart
    Biochim Biophys Acta Gene Regul Mech (2020) , 194604-194604. PubMed  Europe PubMed DOI  V
    8. 2018
  8. Leo,M., Fanelli,G., Di Vito,S., Traversetti,B., La Greca,M., Palladino,R.A., Montanari,A., Francisci,S. and Filetici,P.
    Ubiquitin protease Ubp8 is necessary for S. cerevisiae respiration
    Biochim Biophys Acta (2018) PubMed  Europe PubMed DOI
  9. Morrow,M.E., Morgan,M.T., Clerici,M., Growkova,K., Yan,M., Komander,D., Sixma,T.K., Simicek,M. and Wolberger,C.
    Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins
    EMBO Rep (2018) 19, e45680-e45680. PubMed  Europe PubMed DOI  S
    10. 2016
  10. Morgan,M.T., Haj-Yahya,M., Ringel,A.E., Bandi,P., Brik,A. and Wolberger,C.
    Structural basis for histone H2B deubiquitination by the SAGA DUB module
    Science (2016) 351, 725-728. PubMed  Europe PubMed DOI  S
    11. 2013
  11. Huang,O.W. and Cochran,A.G.
    Regulation of deubiquitinase proteolytic activity
    Curr Opin Struct Biol (2013) 23, 806-811. PubMed  Europe PubMed DOI  S
    12. 2012
  12. Samara,N.L., Ringel,A.E. and Wolberger,C.
    A role for intersubunit interactions in maintaining SAGA deubiquitinating module structure and activity
    Structure (2012) 20, 1414-1424. PubMed  Europe PubMed DOI
  13. Weake,V.M. and Workman,J.L.
    SAGA function in tissue-specific gene expression
    Trends Cell Biol (2012) 22, 177-184. PubMed  Europe PubMed DOI
    14. 2011
  14. Atanassov,B.S., Koutelou,E. and Dent,S.Y.
    The role of deubiquitinating enzymes in chromatin regulation
    FEBS Lett (2011) 585, 2016-2023. PubMed  Europe PubMed DOI  PMC  EPMC
  15. Weake,V.M., Dyer,J.O., Seidel,C., Box,A., Swanson,S.K., Peak,A., Florens,L., Washburn,M.P., Abmayr,S.M. and Workman,J.L.
    Post-transcription initiation function of the ubiquitous SAGA complex in tissue-specific gene activation
    Genes Dev (2011) 25, 1499-1509. PubMed  Europe PubMed DOI
  16. Wilson,M.A., Koutelou,E., Hirsch,C., Akdemir,K., Schibler,A., Barton,M.C. and Dent,S.Y.
    Ubp8 and SAGA regulate Snf1 AMP kinase activity
    Mol Cell Biol (2011) 31, 3126-3135. PubMed  Europe PubMed DOI  PMC  EPMC
    17. 2010
  17. Koutelou,E., Hirsch,C.L. and Dent,S.Y.
    Multiple faces of the SAGA complex
    Curr Opin Cell Biol (2010) 22, 374-382. PubMed  Europe PubMed DOI  PMC  EPMC
  18. Samara,N.L., Datta,A.B., Berndsen,C.E., Zhang,X., Yao,T., Cohen,R.E. and Wolberger,C.
    Structural insights into the assembly and function of the SAGA deubiquitinating module
    Science (2010) 328, 1025-1029. PubMed  Europe PubMed DOI  S  I
    19. 2005
  19. Ingvarsdottir,K., Krogan,N.J., Emre,N.C., Wyce,A., Thompson,N.J., Emili,A., Hughes,T.R., Greenblatt,J.F. and Berger,S.L.
    H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex
    Mol Cell Biol (2005) 25, 1162-1172. PubMed  Europe PubMed DOI  PMC  EPMC
    20. 2004
  20. [YEAR:16-1-2004]Daniel,J.A., Torok,M.S., Sun,Z.W., Schieltz,D., Allis,C.D., Yates,J.R., III and Grant,P.A.
    Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription
    J Biol Chem (16-1-2004) 279, 1867-1871. PubMed  Europe PubMed DOI
  21. Powell,D.W., Weaver,C.M., Jennings,J.L., McAfee,K.J., He,Y., Weil,P.A. and Link,A.J.
    Cluster analysis of mass spectrometry data reveals a novel component of SAGA
    Mol Cell Biol (2004) 24, 7249-7259. PubMed  Europe PubMed DOI  PMC  EPMC
  22. Wyce,A., Henry,K.W. and Berger,S.L.
    H2B ubiquitylation and de-ubiquitylation in gene activation
    Novartis Found Symp (2004) 259, 63-73. PubMed  Europe PubMed
    23. 2003
  23. [YEAR:1-11-2003]Henry,K.W., Wyce,A., Lo,W.S., Duggan,L.J., Emre,N.C., Kao,C.F., Pillus,L., Shilatifard,A., Osley,M.A. and Berger,S.L.
    Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8
    Genes Dev (1-11-2003) 17, 2648-2663. PubMed  Europe PubMed DOI  PMC  EPMC

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