Literature for peptidase C19.073: ubiquitin-specific peptidase 49

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

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    2024
  1. Ding,Y., Liu,Z., Dai,X., Ruan,R., Zhong,H., Wu,Z., Yao,Y., Chen,J., Deng,J. and Xiong,J.
    USP49 promotes adenocarcinoma of the esophagogastric junction malignant progression via activating SHCBP1-beta-catenin-GPX4 axis
    Carcinogenesis PubMed  Europe PubMed DOI  K
  2. Geng,H., Qi,L., You,L., Feng,W., Yang,X. and Lei,M.
    miR-361-3p overexpression promotes apoptosis and inflammation by regulating the USP49/IkappaBalpha/NF-kappaB pathway to aggravate sepsis-induced myocardial injury
    Toxicol Res (Camb)13, tfae190-tfae190. PubMed  Europe PubMed DOI
  3. Li,L., Yang,N., Sun,J.H., Wei,L.J. and Gao,Y.
    IGF2BP3-dependent N6-methyladenosine modification of USP49 promotes carboplatin resistance in retinoblastoma by enhancing autophagy via regulating the stabilization of SIRT1
    Kaohsiung J Med Sci PubMed  Europe PubMed DOI
  4. 2023
  5. Campos-Iglesias,D., Fraile,J.M., Bretones,G., Montero,A.A., Bonzon-Kulichenko,E., Vazquez,J., Lopez-Otin,C. and Freije,J.M.P.
    USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy
    Cell Death Dis14, 60-60. PubMed  Europe PubMed DOI
  6. 2022
  7. Liu,Z., Li,J., Ding,Y., Ma,M., Chen,J., Lei,W., Li,L., Yao,Y., Yu,X., Zhong,M., Liao,Q., Fang,W., Fan,L., Huang,C., Zhong,H., Wen,Q., Fang,Z., Chen,J., Huang,S., Xiong,J., Xiang,X. and Deng,J.
    USP49 mediates tumor progression and poor prognosis through a YAP1-dependent feedback loop in gastric cancer
    Oncogene41, 2555-2570. PubMed  Europe PubMed DOI  K
  8. Shi,L., Shen,X. and Shen,Y.
    USP49-mediated histone H2B deubiquitination regulates HCT116 cell proliferation through MDM2-p53 axis
    Mol Cell BiolMCB0043421-MCB0043421. PubMed  Europe PubMed DOI
  9. Tu,R., Kang,W., Kang,Y., Chen,Z., Zhang,P., Xiong,X., Ma,J., Du,R.L. and Zhang,C.
    c-MYC-USP49-BAG2 axis promotes proliferation and chemoresistance of colorectal cancer cells in vitro
    Biochem Biophys Res Commun607, 117-123. PubMed  Europe PubMed DOI
  10. 2021
  11. Zhuang,Y.Y., Zhong,W., Xia,Z.S., Lin,S.Z., Chan,M.C., Jiang,K., Li,W.F. and Xu,X.Y.
    miR-5000-3p confers oxaliplatin resistance by targeting ubiquitin-specific peptidase 49 in colorectal cancer
    Cell Death Discov7, 129-129. PubMed  Europe PubMed DOI
  12. 2019
  13. Pan,T., Song,Z., Wu,L., Liu,G., Ma,X., Peng,Z., Zhou,M., Liang,L., Liu,B., Liu,J., Zhang,J., Zhang,X., Huang,R., Zhao,J., Li,Y., Ling,X., Luo,Y., Tang,X., Cai,W., Deng,K., Li,L. and Zhang,H.
    USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication
    elife8, PubMed  Europe PubMed DOI
  14. Shen,W.M., Yin,J.N., Xu,R.J., Xu,D.F. and Zheng,S.Y.
    Ubiquitin specific peptidase 49 inhibits non-small cell lung cancer cell growth by suppressing PI3K/AKT signaling
    Kaohsiung J Med Sci35, 401-407. PubMed  Europe PubMed DOI
  15. Ye,L., Zhang,Q., Liuyu,T., Xu,Z., Zhang,M.X., Luo,M.H., Zeng,W.B., Zhu,Q., Lin,D. and Zhong,B.
    USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA
    PLoS Pathog15, e1007680-e1007680. PubMed  Europe PubMed DOI
  16. 2018
  17. Tu,R., Kang,W., Yang,X., Zhang,Q., Xie,X., Liu,W., Zhang,J., Zhang,X.D., Wang,H. and Du,R.L.
    USP49 participates in the DNA damage response by forming a positive feedback loop with p53
    Cell Death Dis9, 553-553. PubMed  Europe PubMed DOI
  18. 2017
  19. Luo,K., Li,Y., Yin,Y., Li,L., Wu,C., Chen,Y., Nowsheen,S., Hu,Q., Zhang,L., Lou,Z. and Yuan,J.
    USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51-AKT signaling
    EMBO J36, 1434-1446. PubMed  Europe PubMed DOI
  20. 2004
  21. [YEAR:30-1-2004]Quesada,V., Diaz-Perales,A., Gutierrez-Fernandez,A., Garabaya,C., Cal,S. and Lopez-Otin,C.
    Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases
    Biochem Biophys Res Commun314, 54-62. PubMed  Europe PubMed DOI