Literature for peptidase C19.059: ubiquitin-specific peptidase 35

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

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    2025
  1. Cao,J., Wu,T., Zhou,T., Jiang,Z., Ren,Y., Yu,J., Wang,J., Qian,C., Wu,G., He,L., Li,H., Lin,R., Liu,M. and Gu,H.
    USP35 promotes the growth of ER positive breast cancer by inhibiting ferroptosis via BRD4-SLC7A11 axis
    Commun Biol8, 64-64. PubMed  Europe PubMed DOI
  2. Guo,Y., Lin,Z., Zhou,Z., Zhang,W., Mao,S., Shan,Z., Wu,P. and Yao,X.
    Oncogenic and immunological functions of USP35 in pan-cancer and its potential as a biomarker in kidney clear cell carcinoma
    BMC Cancer25, 617-617. PubMed  Europe PubMed DOI  K
  3. Zhang,H., Zhu,J., He,R., Xu,L., Chen,Y., Yu,H., Sun,X., Wan,S., Yin,X., Liu,Y., Gao,J., Li,Y., Li,Z., Lu,Y. and Xu,Q.
    Deubiquitination enzyme USP35 negatively regulates MAVS signaling to inhibit anti-tumor immunity
    Cell Death Dis16, 138-138. PubMed  Europe PubMed DOI
  4. 2024
  5. Dai,D.L., Xie,C., Zhong,L.Y., Liu,S.X., Zhang,L.L., Zhang,H., Wu,X.P., Wu,Z.M., Kang,K., Li,Y., Sun,Y.M., Xia,T.L., Zhang,C.S., Zhang,A., Shi,M., Sun,C., Chen,M.L., Zhao,G.X., Bu,G.L., Liu,Y.T., Huang,K.Y., Zhao,Z., Li,S.X., Zhang,X.Y., Yuan,Y.F., Wen,S.J., Zhang,L., Li,B.K., Zhong,Q. and Zeng,M.S.
    AXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation
    Signal Transduct Target Ther9, 281-281. PubMed  Europe PubMed DOI
  6. Li,W., Li,J., Li,W., Li,J., Zheng,W., Cheng,J., Zhang,X., Yang,B., Dong,J. and Sun,X.
    FUS-stabilized USP35 promotes growth, invasion and angiogenesis in NSCLC through deubiquitinating VEGFA
    Gen Physiol Biophys43, 301-312. PubMed  Europe PubMed DOI  K
  7. Lian,W., Hong,C., Chen,D. and Wang,C.
    USP35 promotes breast cancer progression by regulating PFK-1 ubiquitination to mediate glycolysis
    Am J Physiol Cell Physiol PubMed  Europe PubMed DOI  K
  8. Ma,C., Tian,Z., Wang,D., Gao,W., Qian,L., Zang,Y., Xu,X., Jia,J. and Liu,Z.
    Ubiquitin-specific Protease 35 Promotes Gastric Cancer Metastasis by Increasing the Stability of Snail1
    Int J Biol Sci20, 953-967. PubMed  Europe PubMed DOI  K
  9. Wang,S., Li,X., Wang,T., Sun,Z., Feng,E. and Jin,Y.
    Overexpression of USP35 enhances the protective effect of hUC-MSCs and their extracellular vesicles in oxygen-glucose deprivation/reperfusion-induced SH-SY5Y cells via stabilizing FUNDC1
    Commun Biol7, 1330-1330. PubMed  Europe PubMed DOI
  10. Zhang,D., Li,J., Zhang,C., Xue,J., Li,P., Shang,K., Zhang,X. and Lang,B.
    The deubiquitinating enzyme USP35 regulates the stability of NRF2 protein
    Open Life Sci19, 20220935-20220935. PubMed  Europe PubMed DOI
  11. 2023
  12. Lv,T., Zhang,B., Jiang,C., Zeng,Q., Yang,J. and Zhou,Y.
    USP35 promotes hepatocellular carcinoma progression by protecting PKM2 from ubiquitinationƒ_'mediated degradation
    Int J Oncol63, PubMed  Europe PubMed DOI
  13. Park,J., Shin,S.C., Jin,K.S., Lim,M.J., Kim,Y., Kim,E.E. and Song,E.J.
    USP35 dimer prevents its degradation by E3 ligase CHIP through auto-deubiquitinating activity
    Cell Mol Life Sci80, 112-112. PubMed  Europe PubMed DOI
  14. Wang,L., Wang,J., Ma,X., Ju,G., Shi,C., Wang,W. and Wu,J.
    USP35 promotes HCC development by stabilizing ABHD17C and activating the PI3K/AKT signaling pathway
    Cell Death Discov9, 421-421. PubMed  Europe PubMed DOI  K
  15. Wang,S., Wang,T., Zhang,X., Cheng,S., Chen,C., Yang,G., Wang,F., Wang,R., Zhang,Q., Yang,D., Zhang,Y., Liu,S., Qin,H., Liu,Q. and Liu,H.
    The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma
    Cell Death Differ30, 1757-1770. PubMed  Europe PubMed DOI  K
  16. 2022
  17. Lin,G., Huang,T., Zhang,X. and Wang,G.
    Deubiquitinase USP35 stabilizes BRPF1 to activate mevalonate (MVA) metabolism during prostate tumorigenesis
    Cell Death Discov8, 453-453. PubMed  Europe PubMed DOI
  18. Liu,C., Chen,Z., Ding,X., Qiao,Y. and Li,B.
    Ubiquitin-specific protease 35 (USP35) mediates cisplatin-induced apoptosis by stabilizing BIRC3 in non-small cell lung cancer
    Lab Invest102, 524-533. PubMed  Europe PubMed DOI  K
  19. Wang,W., Wang,M., Xiao,Y., Wang,Y., Ma,L., Guo,L., Wu,X., Lin,X. and Zhang,P.
    USP35 mitigates endoplasmic reticulum stress-induced apoptosis by stabilizing RRBP1 in non-small cell lung cancer
    Mol Oncol16, 1572-1590. PubMed  Europe PubMed DOI
  20. Zhang,Q., Liu,Y.J., Li,J.P., Zeng,S.H., Shen,H., Han,M., Guo,S., Liu,S.L. and Zou,X.
    USP35 is a Potential Immunosuppressive Factor in Skin Cutaneous Melanoma
    J Inflamm Res15, 3065-3082. PubMed  Europe PubMed DOI
  21. 2021
  22. Cao,J., Wu,D., Wu,G., Wang,Y., Ren,T., Wang,Y., Lv,Y., Sun,W., Wang,J., Qian,C., He,L., Yang,K., Li,H. and Gu,H.
    USP35, regulated by estrogen and AKT, promotes breast tumorigenesis by stabilizing and enhancing transcriptional activity of estrogen receptor alpha
    Cell Death Dis12, 619-619. PubMed  Europe PubMed DOI
  23. Tang,Z., Jiang,W., Mao,M., Zhao,J., Chen,J. and Cheng,N.
    Deubiquitinase USP35 modulates ferroptosis in lung cancer via targeting ferroportin
    Clin Transl Med11, e390-e390. PubMed  Europe PubMed DOI
  24. Wang,W., Lin,H., Zheng,E., Hou,Z., Liu,Y., Huang,W., Chen,D., Feng,J., Li,J. and Li,L.
    Regulation of survivin protein stability by USP35 is evolutionarily conserved
    Biochem Biophys Res Commun574, 48-55. PubMed  Europe PubMed DOI
  25. Zhang,J., Chen,Y., Chen,X., Zhang,W., Zhao,L., Weng,L., Tian,H., Wu,Z., Tan,X., Ge,X., Wang,P. and Fang,L.
    Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer
    Cell Death Differ28, 139-155. PubMed  Europe PubMed DOI  K
  26. 2018
  27. Leznicki,P., Natarajan,J., Bader,G., Spevak,W., Schlattl,A., Rehman,S.A.A., Pathak,D., Weidlich,S., Zoephel,A., Bordone,M.C., Barbosa-Morais,N.L., Boehmelt,G. and Kulathu,Y.
    Expansion of DUB functionality by alternative isoforms: USP35, a case study
    J Cell Sci131, jcs212753-jcs212753. PubMed  Europe PubMed DOI
  28. Park,J., Kwon,M.S., Kim,E.E., Lee,H. and Song,E.J.
    USP35 regulates mitotic progression by modulating the stability of Aurora B
    Nat Commun9, 688-688. PubMed  Europe PubMed DOI
  29. Park,J. and Song,E.J.
    Deubiquitinase USP35 as a novel mitotic regulator via maintenance of Aurora B stability
    BMB Rep51, 261-262. PubMed  Europe PubMed DOI
  30. 2015
  31. Liu,C., Wang,L., Chen,W., Zhao,S., Yin,C., Lin,Y., Jiang,A. and Zhang,P.
    USP35 activated by miR let-7a inhibits cell proliferation and NF-kappaB activation through stabilization of ABIN-2
    Oncotarget6, 27891-27906. PubMed  Europe PubMed DOI
  32. Wang,Y., Serricchio,M., Jauregui,M., Shanbhag,R., Stoltz,T., Di Paolo,C.T., Kim,P.K. and McQuibban,G.A.
    Deubiquitinating enzymes regulate PARK2-mediated mitophagy
    Autophagy11, 595-606. PubMed  Europe PubMed DOI
  33. 2004
  34. [YEAR:30-1-2004]Quesada,V., Diaz-Perales,A., Gutierrez-Fernandez,A., Garabaya,C., Cal,S. and Lopez-Otin,C.
    Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases
    Biochem Biophys Res Commun314, 54-62. PubMed  Europe PubMed DOI
  35. 2003
  36. Puente,X.S., Sanchez,L.M., Overall,C.M. and Lopez-Otin,C.
    Human and mouse proteases: a comparative genomic approach
    Nat Rev Genet4, 544-558. PubMed  Europe PubMed DOI