Literature for peptidase C19.057: ubiquitin-specific peptidase 44

(Topics flags: K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Wu,P., Xiao,W., Ni,J., Lou,Y. and Xu,C.
   USP44 promotes chemotherapeutic drug resistance of triple negative breast cancer through EZH2 protein stability
   Cancer Biol Ther (2025) 26, 2529652-2529652. PubMed  Europe PubMed DOI  PMC  EPMC  K
2. Yang,H., Sun,T., Sun,Z., Wang,H., Liu,D., Wu,D., Qin,T. and Zhou,M.
   Unravelling the role of ubiquitin-specific proteases in breast carcinoma: insights into tumour progression and immune microenvironment modulation
   World J Surg Oncol (2025) 23, 60-60. PubMed  Europe PubMed DOI  PMC  EPMC  V
3. Zeng,L., Li,Y.Q., He,S.W., Xu,H., Zhang,R., Chen,K., Qin,L.J., Zhu,X.H., Li,Y.L., Li,L., Liu,N. and Wang,H.Y.
   The deubiquitinase USP44 enhances cisplatin chemosensitivity through stabilizing STUB1 to promote LRPPRC degradation in neuroblastoma
   Neuro Oncol (2025) 27, 492-507. PubMed  Europe PubMed DOI
2024
4. Chen,S., Wu,K., Zong,Y., Hou,Z., Deng,Z. and Xia,Z.
   USP44 regulates HEXIM1 stability to inhibit tumorigenesis and metastasis of oral squamous cell carcinoma
   Biol Direct (2024) 19, 143-143. PubMed  Europe PubMed DOI  PMC  EPMC  K
5. Ekstrom,T.L., Hussain,S., Bedekovics,T., Ali,A., Paolini,L., Mahmood,H., Rosok,R.M., Koster,J., Johnsen,S.A. and Galardy,P.J.
   USP44 overexpression drives a MYC-like gene expression program in neuroblastoma through epigenetic reprogramming
   Mol Cancer Res (2024) 22, 812-825. PubMed  Europe PubMed DOI
6. Liu,Y., Yuan,M., Xu,X., Yang,H., Yao,Y., Hou,P., Yu,W. and Ji,M.
   USP44 inactivation accelerates the progression of thyroid cancer by inducing ubiquitylation and degradation of p21
   Int J Biol Sci (2024) 20, 5223-5238. PubMed  Europe PubMed DOI  PMC  EPMC
7. Wang,J., Liang,Y., Wang,K., Lin,L., Peng,X., Li,W., Li,Y., Liao,H., Li,J., Qiao,L. and Li,L.
   Effect of subcutaneous adipose tissue-associated CSRP2 on the progression of prostate cancer via the WDR5/USP44 pathway
   Am J Cancer Res (2024) 14, 5321-5337. PubMed  Europe PubMed DOI  PMC  EPMC
8. Zhang,B., Sun,R., Gu,M., Jiang,Z., Wang,Y., Zhang,L., Liu,X. and Chi,Z.
   RNA-binding protein NOVA1 promotes acute T-lymphocyte leukemia progression by stabilizing USP44 mRNA
   Biochem Cell Biol (2024) 102, 60-72. PubMed  Europe PubMed DOI  K
2022
9. Chen,Y., Zhao,Y., Yang,X., Ren,X., Huang,S., Gong,S., Tan,X., Li,J., He,S., Li,Y., Hong,X., Li,Q., Ding,C., Fang,X., Ma,J. and Liu,N.
   USP44 regulates irradiation-induced DNA double-strand break repair and suppresses tumorigenesis in nasopharyngeal carcinoma
   Nat Commun (2022) 13, 501-501. PubMed  Europe PubMed DOI  PMC  EPMC
10. Lou,Y., Ye,M., Xu,C. and Tao,F.
    Insight into the physiological and pathological roles of USP44, a potential tumor target (Review)
    Oncol Lett (2022) 24, 455-455. PubMed  Europe PubMed DOI  PMC  EPMC
2021
11. Zhang,Y., Mandemaker,I.K., Matsumoto,S., Foreman,O., Holland,C.P., Lloyd,W.R., Sugasawa,K., Vermeulen,W., Marteijn,J.A. and Galardy,P.J.
    USP44 Stabilizes DDB2 to Facilitate Nucleotide Excision Repair and Prevent Tumors
    Front Cell Dev Biol (2021) 9, 663411-663411. PubMed  Europe PubMed DOI  PMC  EPMC
2020
12. Huang,T., Zhang,Q., Ren,W., Yan,B., Yi,L., Tang,T., Lin,H. and Zhang,Y.
    USP44 suppresses proliferation and enhances apoptosis in colorectal cancer cells by inactivating the Wnt/beta-catenin pathway via Axin1 deubiquitination
    Cell Biol Int (2020) PubMed  Europe PubMed DOI
13. Marsh,D.J., Ma,Y. and Dickson,K.A.
    Histone Monoubiquitination in Chromatin Remodelling: Focus on the Histone H2B Interactome and Cancer
    Cancers (Basel) (2020) 12 PubMed  Europe PubMed DOI  PMC  EPMC  V
14. Yang,J., Wei,P., Barbi,J., Huang,Q., Yang,E., Bai,Y., Nie,J., Gao,Y., Tao,J., Lu,Y., Xie,C., Hou,X., Ren,J., Wu,X., Meng,J., Zhang,Y., Fu,J., Kou,W., Gao,Y., Chen,Z., Liang,R., Tsun,A., Li,D., Guo,W., Zhang,S., Zheng,S.G., Niu,J., Galardy,P., Tong,X., Shi,G., Li,H., Pan,F. and Li,B.
    The deubiquitinase USP44 promotes Treg function during inflammation by preventing FOXP3 degradation
    EMBO Rep (2020) , e50308-e50308. PubMed  Europe PubMed DOI
15. Zhang,H.Y., Liao,B.W., Xu,Z.S., Ran,Y., Wang,D.P., Yang,Y., Luo,W.W. and Wang,Y.Y.
    USP44 positively regulates innate immune response to DNA viruses through deubiquitinating MITA
    PLoS Pathog (2020) 16, e1008178-e1008178. PubMed  Europe PubMed DOI
16. Zheng,J., Wang,B., Zheng,R., Zhang,J., Huang,C., Zheng,R., Huang,Z., Qiu,W., Liu,M., Yang,K., Mao,Z., Ji,A. and Yuan,Y.
    Linc-RA1 inhibits autophagy and promotes radioresistance by preventing H2Bub1/USP44 combination in glioma cells
    Cell Death Dis (2020) 11, 758-758. PubMed  Europe PubMed DOI  PMC  EPMC
2019
17. Lin,Y.H., Forster,M., Liang,Y., Yu,M., Wang,H., Robert,F., Langlais,D., Pelletier,J., Clare,S. and Nijnik,A.
    USP44 is dispensable for normal hematopoietic stem cell function, lymphocyte development, and B-cell-mediated immune response in a mouse model
    Exp Hematol (2019) 72, 1-8. PubMed  Europe PubMed DOI
18. Park,J.M., Lee,J.E., Park,C.M. and Kim,J.H.
    USP44 promotes the tumorigenesis of prostate cancer cells through EZH2 protein stabilization
    Mol Cells (2019) 42, 17-27. PubMed  Europe PubMed DOI
19. Yang,C., Zhu,S., Yang,H., Deng,S., Fan,P., Li,M. and Jin,X.
    USP44 suppresses pancreatic cancer progression and overcomes gemcitabine resistance by deubiquitinating FBP1
    Am J Cancer Res (2019) 9, 1722-1733. PubMed  Europe PubMed  PMC  EPMC
20. Zhang,Y.K., Tian,W.Z., Zhang,R.S., Zhang,Y.J. and Ma,H.T.
    Ubiquitin-specific protease 44 inhibits cell growth by suppressing AKT signaling in non-small cell lung cancer
    Kaohsiung J Med Sci (2019) 35, 535-541. PubMed  Europe PubMed DOI
2017
21. Zou,Y., Qiu,G., Jiang,L., Cai,Z., Sun,W., Hu,H., Lu,C., Jin,W. and Hu,G.
    Overexpression of ubiquitin specific proteases 44 promotes the malignancy of glioma by stabilizing tumor-promoter securin
    Oncotarget (2017) 8, 58231-58246. PubMed  Europe PubMed DOI
2015
22. Liu,T., Sun,B., Zhao,X., Li,Y., Zhao,X., Liu,Y., Yao,Z., Gu,Q., Dong,X., Shao,B., Lin,X., Liu,F. and An,J.
    USP44+ cancer stem cell subclones contribute to breast cancer aggressiveness by promoting vasculogenic mimicry
    Mol Cancer Ther (2015) 14, 2121-2131. PubMed  Europe PubMed DOI
2013
23. Anon
    A deubiquitinase protects against aneuploidy and tumor formation
    Cancer Discov (2013) 3, 11-11. DOI
24. Mosbech,A., Lukas,C., Bekker-Jensen,S. and Mailand,N.
    The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases
    J Biol Chem (2013) 288, 16579-16587. PubMed  Europe PubMed DOI
2012
25. Fuchs,G., Shema,E., Vesterman,R., Kotler,E., Wolchinsky,Z., Wilder,S., Golomb,L., Pribluda,A., Zhang,F., Haj-Yahya,M., Feldmesser,E., Brik,A., Yu,X., Hanna,J., Aberdam,D., Domany,E. and Oren,M.
    RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation
    Mol Cell (2012) 46, 662-673. PubMed  Europe PubMed DOI  PMC  EPMC
26. Holland,A.J. and Cleveland,D.W.
    The deubiquitinase USP44 is a tumor suppressor that protects against chromosome missegregation
    J Clin Invest (2012) 122, 4325-4328. PubMed  Europe PubMed DOI
27. Zhang,Y., Foreman,O., Wigle,D.A., Kosari,F., Vasmatzis,G., Salisbury,J.L., van Deursen,J. and Galardy,P.J.
    USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis
    J Clin Invest (2012) 122, 4362-4374. PubMed  Europe PubMed DOI
2011
28. Zhang,Y., van Deursen,J. and Galardy,P.J.
    Overexpression of ubiquitin specific protease 44 (USP44) induces chromosomal instability and is frequently observed in human T-cell leukemia
    PLoS ONE (2011) 6, e23389-e23389. PubMed  Europe PubMed DOI  PMC  EPMC
2010
29. Suresh,B., Ramakrishna,S., Lee,H.J., Choi,J.H., Kim,J.Y., Ahn,W.S. and Baek,K.H.
    K48- and K63-linked polyubiquitination of deubiquitinating enzyme USP44
    Cell Biol Int (2010) 34, 799-808. PubMed  Europe PubMed DOI
2007
30. Stegmeier,F., Rape,M., Draviam,V.M., Nalepa,G., Sowa,M.E., Ang,X.L., McDonald,E.R., III, Li,M.Z., Hannon,G.J., Sorger,P.K., Kirschner,M.W., Harper,J.W. and Elledge,S.J.
    Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities
    Nature (2007) 446, 876-881. PubMed  Europe PubMed DOI
2004
31. [YEAR:30-1-2004]Quesada,V., Diaz-Perales,A., Gutierrez-Fernandez,A., Garabaya,C., Cal,S. and Lopez-Otin,C.
    Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases
    Biochem Biophys Res Commun (30-1-2004) 314, 54-62. PubMed  Europe PubMed DOI
2003
32. Puente,X.S., Sanchez,L.M., Overall,C.M. and Lopez-Otin,C.
    Human and mouse proteases: a comparative genomic approach
    Nat Rev Genet (2003) 4, 544-558. PubMed  Europe PubMed DOI