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Literature for peptidase C19.054: ubiquitin-specific peptidase 28

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, T Target, R Splicing, K Knockout, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Belal,H., Ng,E.F.Y., Ohta,M. and Meitinger,F.<br>Cancer-associated USP28 missense mutations disrupt 53BP1 interaction and p53 stabilization<br>Nat Commun (2025) 16, 10310-10310. PubMed  Europe PubMed DOI  PMC  EPMC
  2. Bratt,A.S., Kilgas,S., Tarazona Guzman,M.I., Magin,R.S., Jaen Maisonet,I., Starnbach,C.A., Teh,W.P., Varca,A.C., Hu,B., Tarazona Guzman,E., Seo,H.S., Dhe-Paganon,S., Girardi,N.M., Adelmant,G., Marto,J.A., Chowdhury,D. and Buhrlage,S.J.<br>Pharmacologic interrogation of USP28 cellular function in p53 signaling<br>Cell Chem Biol (2025) 32, 1166-1182. PubMed  Europe PubMed DOI  I
  3. Cai,C., Luo,H., Peng,J., Zhen,X., Shen,X., Xi,X., Zhu,J., Fang,Y., Chen,X., Wang,J., Yu,C., Zhang,P. and Xu,C.<br>The Deubiquitinase USP28 Maintains the Expression of PPARgamma and Its Inactivation Protects Mice from Diet-Induced MASH and Hepatocarcinoma<br>Mol Ther (2025) PubMed  Europe PubMed DOI
  4. Han,F., Qi,G., Li,R., Peng,J., Yan,S., Yuan,C., Kong,B. and Ma,H.<br>USP28 promotes PARP inhibitor resistance by enhancing SOX9-mediated DNA damage repair in ovarian cancer<br>Cell Death Dis (2025) 16, 305-305. PubMed  Europe PubMed DOI  PMC  EPMC
  5. Li,X., He,N., Lv,Y., Wang,H., Zhang,M., Zhai,H., Yang,Z., Yang,Y., Guo,D., Cao,Z. and Chen,Y.<br>Broad-spectrum ubiquitin-specific protease inhibition as a mechanism for the cytotoxicity of YM155 in cancers<br>Sci Rep (2025) 15, 11054-11054. PubMed  Europe PubMed DOI  PMC  EPMC  I
  6. Li,Z., Wang,Y., Hu,J., Du,J., Nie,H., Xi,Y., Huang,Y., Wang,K., Zhang,K., Xu,Q., Cheng,L., Huang,D. and Tu,L.<br>USP28 knockdown and small molecule inhibitors promote KRT1 destabilization and sensitize hepatocellular carcinoma cells to sorafenib<br>Exp Cell Res (2025) 448, 114558-114558. PubMed  Europe PubMed DOI
  7. Meng,Y., Xu,Y., Qiu,A., Lin,M., Yang,L. and Huang,Y.<br>USP28-mediated deubiquitination of FOXK1 activates the Hippo signaling pathway to regulate cell proliferation and radiosensitivity in lung cancer<br>Life Sci (2025) , 123483-123483. PubMed  Europe PubMed DOI
  8. Mennerich,D., Ashok,Y., Vela-Rodriguez,C., Hentila,H.I., Rall-Scharpf,M., Wiesmuller,L., Prunskaite-Hyyrylainen,R., Lehtio,L. and Kietzmann,T.<br>The E3 ubiquitin ligase DTX3L and the deubiquitinase USP28 fine-tune DNA repair through mutual regulation of their protein levels<br>iScience (2025) 28, 112990-112990. PubMed  Europe PubMed DOI  PMC  EPMC  K
  9. Wang,Z., Qian,C., Xiong,Y., Zhang,D., Inuzuka,H., Zhong,Y., Xie,L., Chen,X., Jin,J. and Wei,W.<br>USP28-Based Deubiquitinase-Targeting Chimeras for Cancer Treatment<br>J Am Chem Soc (2025) PubMed  Europe PubMed DOI
  10. Wen,W., Zhou,Z., Chen,C. and Chen,M.<br>Deubiquitinase USP28 promotes the malignant progression and radio-resistance of hepatocellular carcinoma by stabilizing WDHD1<br>Naunyn Schmiedebergs Arch Pharmacol (2025) PubMed  Europe PubMed DOI  K
  11. Xiong,M., He,Z., Wen,L. and Zhao,A.<br>Decidual stromal cells-derived exosomes incured insufficient migration and invasion of trophoblast because of abnormal ubiquitination and degradation of Snail mediated by miR-92b-3p/USP28<br>BMC Biol (2025) 23, 222-222. PubMed  Europe PubMed DOI  PMC  EPMC
    12. 2024
  12. Han,J., Lin,L., Fang,Z., Ye,B., Han,X., Xu,J., Han,B., Min,J., Qian,J., Wu,G., Wang,Y. and Liang,G.<br>Cardiomyocyte-derived USP28 negatively regulates antioxidant response and promotes cardiac hypertrophy via deubiquitinating TRIM21<br>Theranostics (2024) 14, 6236-6248. PubMed  Europe PubMed DOI  PMC  EPMC
  13. Jin,C., Einig,E., Xu,W., Kollampally,R.B., Schlosser,A., Flentje,M. and Popov,N.<br>The dimeric deubiquitinase USP28 integrates 53BP1 and MYC functions to limit DNA damage<br>Nucleic Acids Res (2024) 52, 3011-3030. PubMed  Europe PubMed DOI
  14. Karapurkar,J.K., Colaco,J.C., Suresh,B., Tyagi,A., Woo,S.H., Jo,W.J., Ko,N., Singh,V., Hong,S.H., Oh,S.J., Kim,K.S. and Ramakrishna,S.<br>USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cells<br>Cell Mol Life Sci (2024) 81, 145-145. PubMed  Europe PubMed DOI  PMC  EPMC
  15. Le Menn,G., Pikkarainen,K., Mennerich,D., Miroszewska,D., Kietzmann,T. and Chen,Z.<br>USP28 protects development of inflammation in mouse intestine by regulating STAT5 phosphorylation and IL22 production in T lymphocytes<br>Front Immunol (2024) 15, 1401949-1401949. PubMed  Europe PubMed DOI  PMC  EPMC
  16. Li,Z., Xi,Y., Tu,L., Zhang,X., Huang,Y., Nie,H., Peng,C., Chai,H., Zeng,S., Zheng,X. and Cheng,L.<br>Investigation of the mechanism of USP28-mediated IFITM3 elevation in BCR-ABL-dependent imatinib resistance in CML<br>Biomed Pharmacother (2024) 173, 116315-116315. PubMed  Europe PubMed DOI
  17. Meitinger,F., Belal,H., Davis,R.L., Martinez,M.B., Shiau,A.K., Oegema,K. and Desai,A.<br>Control of cell proliferation by memories of mitosis<br>Science (2024) 383, 1441-1448. PubMed  Europe PubMed DOI
  18. Qiao,Q., Wang,J., Liu,S., Chang,J., Zhou,T., Li,C., Zhang,Y., Jiang,W., Chen,Y., Xu,X., Wu,M. and Li,X.<br>USP28 promotes tumor progression and glycolysis by stabilizing PKM2/Hif1-alpha in cholangiocarcinoma<br>Cell Oncol (Dordr) (2024) 47, 2217-2231. PubMed  Europe PubMed DOI
  19. Song,Y., Wang,L., Zheng,Y., Jia,L., Li,C., Chao,K., Li,L., Sun,S., Wei,Y., Ge,Y., Yang,Y., Zhu,L., Zhang,Y. and Zhao,J.<br>Deubiquitinating enzyme USP28 inhibitor AZ1 alone and in combination with cisplatin for the treatment of non-small cell lung cancer<br>Apoptosis (2024) 29, 1793-1809. PubMed  Europe PubMed DOI  I
  20. Wen,C., Huang,C., Liao,X., Luo,Z. and Huang,C.<br>Mitochondria-targeted Catalase induced cell malignant transformation by the downregulation of p53 protein stability via USP28/miR-200b/PP2A-Calpha axis<br>Arch Biochem Biophys (2024) , 110047-110047. PubMed  Europe PubMed DOI
  21. Xie,S.Y., Liu,S.Q., Zhang,T., Shi,W.K., Xing,Y., Fang,W.X., Zhang,M., Chen,M.Y., Xu,S.C., Fan,M.Q., Li,L.L., Zhang,H., Zhao,N., Zeng,Z.X., Chen,S., Zeng,X.F., Deng,W. and Tang,Q.Z.<br>USP28 Serves as a Key Suppressor of Mitochondrial Morphofunctional Defects and Cardiac Dysfunction in the Diabetic Heart<br>Circulation (2024) 149, 684-706. PubMed  Europe PubMed DOI
  22. Xu,J., Peng,J., Sun,S., Wang,D., Yuan,W., Yang,X., Shi,T., Wang,R., Liu,H., Zhang,P. and Zhu,H.H.<br>Preclinical testing of CT1113, a novel USP28 inhibitor, for the treatment of T-cell acute lymphoblastic leukaemia<br>Br J Haematol (2024) 204, 2301-2318. PubMed  Europe PubMed DOI  I
    23. 2023
  23. Li,J., Peng,J., Wu,L., Shen,X., Zhen,X., Zhang,Y., Ma,H., Xu,Y., Xiong,Q., Zhu,Q. and Zhang,P.<br>The deubiquitinase USP28 maintains the expression of the transcription factor MYCN and is essential in neuroblastoma cells<br>J Biol Chem (2023) 299, 104856-104856. PubMed  Europe PubMed DOI  PMC  EPMC
  24. Liu,Z., Yu,Y., Zhou,S., Zhang,X. and Zhou,Z.<br>Inhibition of Pard3 promotes breast cancer metastasis via the USP28 mediated deubiquitination of Snail1<br>Heliyon (2023) 9, e22599-e22599. PubMed  Europe PubMed DOI  PMC  EPMC  K
  25. Maier,C.R., Hartmann,O., Prieto-Garcia,C., Al-Shami,K.M., Schlicker,L., Vogel,F.C.E., Haid,S., Klann,K., Buck,V., Munch,C., Schmitz,W., Einig,E., Krenz,B., Calzado,M.A., Eilers,M., Popov,N., Rosenfeldt,M.T., Diefenbacher,M.E. and Schulze,A.<br>USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer<br>Cell Death Differ (2023) 30, 1710-1725. PubMed  Europe PubMed DOI  PMC  EPMC
  26. Ren,X., Jiang,M., Ding,P., Zhang,X., Zhou,X., Shen,J., Liu,D., Yan,X. and Ma,Z.<br>Ubiquitin-specific protease 28: the decipherment of its dual roles in cancer development<br>Exp Hematol Oncol (2023) 12, 27-27. PubMed  Europe PubMed DOI  PMC  EPMC  V
  27. Ren,Y., Zhu,X., Fu,K., Zhang,H., Zhao,W., Lin,Y., Fang,Q., Wang,J., Chen,Y. and Guo,D.<br>Inhibition of deubiquitinase USP28 attenuates cyst growth in autosomal dominant polycystic kidney disease<br>Biochem Pharmacol (2023) 207, 115355-115355. PubMed  Europe PubMed DOI
  28. Shen,J., Xie,M., Xu,Y., Qian,Q., Qiu,T., Shi,W., Ren,D., Ji,J. and Huang,J.<br>Identification of the deubiquitinase USP28 as a novel molecular therapeutic target of ovarian cancer<br>Biochem Biophys Res Commun (2023) 638, 184-191. PubMed  Europe PubMed DOI
  29. Xu,Z., Wang,H., Meng,Q., Ding,Y., Zhu,M., Zhou,H., Zhang,N. and Shi,L.<br>Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines<br>Biochem Pharmacol (2023) 215, 115746-115746. PubMed  Europe PubMed DOI  I
  30. Zhou,D., Xu,Z., Huang,Y., Wang,H., Zhu,X., Zhang,W., Song,W., Gao,T., Liu,T., Wang,M., Shi,L., Zhang,N. and Xiong,B.<br>Structure-based discovery of potent USP28 inhibitors derived from Vismodegib<br>Eur J Med Chem (2023) 254, 115369-115369. PubMed  Europe PubMed DOI
  31. Zhou,L., Qin,B., Yassine,D.M., Luo,M., Liu,X., Wang,F. and Wang,Y.<br>Structure and function of the highly homologous deubiquitinases ubiquitin specific peptidase 25 and 28: Insights into their pathophysiological and therapeutic roles<br>Biochem Pharmacol (2023) 213, 115624-115624. PubMed  Europe PubMed DOI
    32. 2022
  32. Prieto-Garcia,C., Hartmann,O., Reissland,M., Braun,F., Bozkurt,S., Pahor,N., Fuss,C., Schirbel,A., Schulein-Volk,C., Buchberger,A., Calzado Canale,M.A., Rosenfeldt,M., Dikic,I., Munch,C. and Diefenbacher,M.E.<br>USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K<br>Mol Oncol (2022) PubMed  Europe PubMed DOI
  33. Sun,X., Cai,M., Wu,L., Zhen,X., Chen,Y., Peng,J., Han,S. and Zhang,P.<br>Ubiquitin-specific protease 28 deubiquitinates TCF7L2 to govern the action of the Wnt signaling pathway in hepatic carcinoma<br>Cancer Sci (2022) 113, 3463-3475. PubMed  Europe PubMed DOI  PMC  EPMC
  34. Toth,R.K., Solomon,R. and Warfel,N.A.<br>Stabilization of PIM Kinases in Hypoxia Is Mediated by the Deubiquitinase USP28<br>Cells (2022) 11 PubMed  Europe PubMed DOI  PMC  EPMC
    35. 2021
  35. Chen,L., Xu,Z., Li,Q., Feng,Q., Zheng,C., Du,Y., Yuan,R. and Peng,X.<br>USP28 facilitates pancreatic cancer progression through activation of Wnt/beta-catenin pathway via stabilising FOXM1<br>Cell Death Dis (2021) 12, 887-887. PubMed  Europe PubMed DOI  PMC  EPMC  K
  36. Kim,H., Choi,H., Im,J.S., Park,S.Y., Shin,G., Yoo,J.H., Kim,G. and Lee,J.K.<br>Stable maintenance of the Mre11-Rad50-Nbs1 complex is sufficient to restore the DNA double-strand break response in cells lacking RecQL4 helicase activity<br>J Biol Chem (2021) , 101148-101148. PubMed  Europe PubMed DOI
  37. Prieto-Garcia,C., Tomaskovic,I., Shah,V.J., Dikic,I. and Diefenbacher,M.<br>USP28: Oncogene or Tumor Suppressor? A Unifying Paradigm for Squamous Cell Carcinoma<br>Cells (2021) 10 PubMed  Europe PubMed DOI  PMC  EPMC
  38. Ruiz,E.J., Pinto-Fernandez,A., Turnbull,A.P., Lan,L., Charlton,T.M., Scott,H.C., Damianou,A., Vere,G., Riising,E.M., Da Costa,C., Krajewski,W.W., Guerin,D., Kearns,J.D., Ioannidis,S., Katz,M., McKinnon,C., O'Connell,J., Moncaut,N., Rosewell,I., Nye,E., Jones,N., Heride,C., Gersch,M., Wu,M., Dinsmore,C.J., Hammonds,T.R., Kim,S., Komander,D., Urbe,S., Clague,M.J., Kessler,B.M. and Behrens,A.<br>USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma<br>elife (2021) 10 PubMed  Europe PubMed DOI  PMC  EPMC
  39. Wang,J., Dong,Y., Ma,H., Wu,L., Zhen,X., Tang,L., Jin,J., Han,S., Zhang,P. and Peng,J.<br>The Deubiquitinase USP28 Stabilizes Expression of RecQ Family Helicases and Maintains the Viability of Triple Negative Breast Cancer Cells<br>J Biol Chem (2021) , 101443-101443. PubMed  Europe PubMed DOI  K
    40. 2019
  40. Gersch,M., Wagstaff,J.L., Toms,A.V., Graves,B., Freund,S.M.V. and Komander,D.<br>Distinct USP25 and USP28 oligomerization states regulate deubiquitinating activity<br>Mol Cell (2019) 74, 436-451. PubMed  Europe PubMed DOI
  41. Haq,S., Das,S., Kim,D.H., Chandrasekaran,A.P., Hong,S.H., Kim,K.S. and Ramakrishna,S.<br>The stability and oncogenic function of LIN28A are regulated by USP28<br>Biochim Biophys Acta Mol Basis Dis (2019) 1865, 599-610. PubMed  Europe PubMed DOI
  42. Li,F., Han,H., Sun,Q., Liu,K., Lin,N., Xu,C., Zhao,Z. and Zhao,W.<br>USP28 regulates deubiquitination of histone H2A and cell proliferation<br>Exp Cell Res (2019) 379, 11-18. PubMed  Europe PubMed DOI  K
  43. Li,P., Huang,Z., Wang,J., Chen,W. and Huang,J.<br>Ubiquitin-specific peptidase 28 enhances STAT3 signaling and promotes cell growth in non-small-cell lung cancer<br>Onco Targets Ther (2019) 12, 1603-1611. PubMed  Europe PubMed DOI  PMC  EPMC
  44. Sauer,F., Klemm,T., Kollampally,R.B., Tessmer,I., Nair,R.K., Popov,N. and Kisker,C.<br>Differential oligomerization of the deubiquitinases USP25 and USP28 regulates their activities<br>Mol Cell (2019) 74, 421-435. PubMed  Europe PubMed DOI  S
    45. 2018
  45. Richter,K., Paakkola,T., Mennerich,D., Kubaichuk,K., Konzack,A., Kippari,H.A., Kozlova,N., Koivunen,P., Haapasaari,K.M., Jukkola-Vuorinen,A., Teppo,H.R., Dimova,E.Y., Bloigu,R., Szabo,Z., Kerkela,R. and Kietzmann,T.<br>USP28 deficiency promotes breast and liver carcinogenesis as well as tumor angiogenesis in a HIF-independent manner<br>Mol Cancer Res (2018) 16, 1000-1012. PubMed  Europe PubMed DOI  K
  46. Wang,X., Liu,Z., Zhang,L., Yang,Z., Chen,X., Luo,J., Zhou,Z., Mei,X., Yu,X., Shao,Z., Feng,Y., Fu,S., Zhang,Z., Wei,D., Jia,L., Ma,J. and Guo,X.<br>Targeting deubiquitinase USP28 for cancer therapy<br>Cell Death Dis (2018) 9, 186-186. PubMed  Europe PubMed DOI  T
  47. Zhao,L.J., Zhang,T., Feng,X.J., Chang,J., Suo,F.Z., Ma,J.L., Liu,Y.J., Liu,Y., Zheng,Y.C. and Liu,H.M.<br>USP28 contributes to the proliferation and metastasis of gastric cancer<br>J Cell Biochem (2018) 120, 7657-7666. PubMed  Europe PubMed DOI
    48. 2017
  48. Kargbo,R.B.<br>Ubiquitin-specific inhibitors for the treatment of cancers, autoimmune, and infectious diseases<br>ACS Med Chem Lett (2017) 8, 1211-1212. PubMed  Europe PubMed DOI  PMC  EPMC  I
  49. Ren,K., Li,Y., Lu,H., Li,Z. and Han,X.<br>miR-3940-5p functions as a tumor suppressor in non-small cell lung cancer cells by targeting cyclin D1 and ubiquitin specific peptidase-28<br>Transl Oncol (2017) 10, 80-89. PubMed  Europe PubMed DOI  PMC  EPMC
  50. Wrigley,J.D., Gavory,G., Simpson,I., Preston,M., Plant,H., Bradley,J., Goeppert,A.U., Rozycka,E., Davies,G., Walsh,J., Valentine,A., McClelland,K., Odrzywol,K.E., Renshaw,J., Boros,J., Tart,J., Leach,L., Nowak,T., Ward,R.A., Harrison,T. and Andrews,D.M.<br>Identification and characterization of dual inhibitors of the USP25/28 deubiquitinating enzyme subfamily<br>ACS Chem Biol (2017) 12, 3113-3125. PubMed  Europe PubMed DOI  I
    51. 2015
  51. Diefenbacher,M.E., Chakraborty,A., Blake,S.M., Mitter,R., Popov,N., Eilers,M. and Behrens,A.<br>Usp28 counteracts Fbw7 in intestinal homeostasis and cancer<br>Cancer Res (2015) 75, 1181-1186. PubMed  Europe PubMed DOI
  52. Sun,X.X., Sears,R.C. and Dai,M.S.<br>Deubiquitinating c-Myc: USP36 steps up in the nucleolus<br>Cell Cycle (2015) 14, 3786-3793. PubMed  Europe PubMed DOI
  53. Taranets,L., Zhu,J., Xu,W. and Popov,N.<br>Fbw7 and Usp28 - enemies and allies<br>Mol Cell Oncol (2015) 2, e995041-e995041. PubMed  Europe PubMed DOI  PMC  EPMC
  54. Wen,Y., Shi,L., Ding,Y., Cui,R., He,W.T., Hu,H.Y. and Zhang,N.<br>The N-terminal ubiquitin-binding region of ubiquitin-specific protease 28 modulates its deubiquitination function: NMR structural and mechanistic insights<br>Biochem J (2015) 471, 155-165. PubMed  Europe PubMed DOI  S
    55. 2014
  55. Diefenbacher,M.E., Popov,N., Blake,S.M., Schulein-Volk,C., Nye,E., Spencer-Dene,B., Jaenicke,L.A., Eilers,M. and Behrens,A.<br>The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer<br>J Clin Invest (2014) 124, 3407-3418. PubMed  Europe PubMed DOI
  56. Schulein-Volk,C., Wolf,E., Zhu,J., Xu,W., Taranets,L., Hellmann,A., Janicke,L.A., Diefenbacher,M.E., Behrens,A., Eilers,M. and Popov,N.<br>Dual regulation of Fbw7 function and oncogenic transformation by Usp28<br>Cell Rep (2014) 9, 1099-1109. PubMed  Europe PubMed DOI
  57. Wen,Y., Cui,R., Zhang,H. and Zhang,N.<br>1H, 13C and 15N backbone and side-chain resonance assignments of the N-terminal ubiquitin-binding domains of the human deubiquitinase Usp28<br>Biomol NMR Assign (2014) 8, 251-254. PubMed  Europe PubMed DOI
  58. Zhen,Y., Knobel,P.A., Stracker,T.H. and Reverter,D.<br>Regulation of USP28 deubiquitinating activity by SUMO conjugation<br>J Biol Chem (2014) 289, 34838-34850. PubMed  Europe PubMed DOI
    59. 2013
  59. Bohgaki,M., Hakem,A., Halaby,M.J., Bohgaki,T., Li,Q., Bissey,P.A., Shloush,J., Kislinger,T., Sanchez,O., Sheng,Y. and Hakem,R.<br>The E3 ligase PIRH2 polyubiquitylates CHK2 and regulates its turnover<br>Cell Death Differ (2013) 20, 812-822. PubMed  Europe PubMed DOI
  60. Wu,Y., Wang,Y., Yang,X.H., Kang,T., Zhao,Y., Wang,C., Evers,B.M. and Zhou,B.P.<br>The deubiquitinase USP28 stabilizes LSD1 and confers stem-cell-like traits to breast cancer cells<br>Cell Rep (2013) 5, 224-236. PubMed  Europe PubMed DOI
    61. 2012
  61. Flugel,D., Gorlach,A. and Kietzmann,T.<br>GSK-3beta regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1alpha<br>Blood (2012) 119, 1292-1301. PubMed  Europe PubMed DOI
    62. 2010
  62. Sacco,J.J., Coulson,J.M., Clague,M.J. and Urbe,S.<br>Emerging roles of deubiquitinases in cancer-associated pathways<br>IUBMB Life (2010) 62, 140-157. PubMed  Europe PubMed DOI  V
    63. 2007
  63. Popov,N., Wanzel,M., Madiredjo,M., Zhang,D., Beijersbergen,R., Bernards,R., Moll,R., Elledge,S.J. and Eilers,M.<br>The ubiquitin-specific protease USP28 is required for MYC stability<br>Nat Cell Biol (2007) 9, 765-774. PubMed  Europe PubMed DOI
  64. Popov,N., Herold,S., Llamazares,M., Schulein,C. and Eilers,M.<br>Fbw7 and Usp28 regulate Myc protein stability in response to DNA damage<br>Cell Cycle (2007) 6, 2327-2331. PubMed  Europe PubMed
    65. 2006
  65. [YEAR:4-8-2006]Zhang,D., Zaugg,K., Mak,T.W. and Elledge,S.J.<br>A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response<br>Cell (4-8-2006) 126, 529-542. PubMed  Europe PubMed DOI
    66. 2001
  66. Valero,R., Bayes,M., Francisca Sanchez-Font,M., Gonzalez-Angulo,O., Gonzalez-Duarte,R. and Marfany,G.<br>Characterization of alternatively spliced products and tissue-specific isoforms of USP28 and USP25<br>Genome Biol (2001) 2, RESEARCH0043-RESEARCH0043. PubMed  Europe PubMed  PMC  EPMC  R

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