Literature for peptidase C19.053: ubiquitin-specific peptidase 37

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2025
1. Fang,S., Wang,Z., Xu,J., Xu,M., Zhou,J., Zhang,Y. and Xue,C.
   USP37-stabilized SALL4 promotes the keloid formation by PI3K/AKT pathway
   Sci Rep (2025) 15, 7553-7553. PubMed  Europe PubMed DOI  PMC  EPMC  K
2. Kochenova,O.V., D'Alessandro,G., Pilger,D., Schmid,E., Richards,S.L., Garcia,M.R., Jhujh,S.S., Voigt,A., Gupta,V., Carnie,C.J., Alex Wu,R., Gueorguieva,N., Lam,S., Stewart,G.S., Walter,J.C. and Jackson,S.P.
   USP37 prevents premature disassembly of stressed replisomes by TRAIP
   Nat Commun (2025) 16, 5333-5333. PubMed  Europe PubMed DOI  PMC  EPMC
3. Tang,M., Li,S., Zhu,Z., Wang,C., Ding,S., Zhang,H., Huang,M., Keast,S., Chen,Z., Yin,L., Nie,L., Su,D., Feng,X. and Chen,J.
   USP37 counteracts HLTF to protect damaged replication forks and promote survival of BRCA1-deficient cells and PARP inhibitor resistance
   Nucleic Acids Res (2025) 53 PubMed  Europe PubMed DOI  PMC  EPMC
4. Zhang,S., Ding,F., Jia,F. and Lu,X.
   USP37 as a novel regulator of NRF2 protein stability and chemoresistance in HCC
   Discov Oncol (2025) 16, 312-312. PubMed  Europe PubMed DOI  PMC  EPMC  K
2024
5. Bolhuis,D.L., Fleifel,D., Bonacci,T., Wang,X., Mouery,B.L., Cook,J.G., Brown,N.G. and Emanuele,M.J.
   USP37 prevents unscheduled replisome unloading through MCM complex deubiquitination
   bioRxiv (2024) PubMed  Europe PubMed DOI  PMC  EPMC
6. Cui,W., Wang,H., Gao,Y., Zhang,X., Xin,J., Li,Z., Li,G., Gao,W. and Zhang,W.
   Deubiquitinase USP37 enhances the anti-HIV-2/SIV ability of the host restriction factor SAMHD1
   J Virol (2024) , e0185824-e0185824. PubMed  Europe PubMed DOI
7. De,S., Chauhan,R., Singh,M. and Singh,N.
   Ubiquitin specific peptidase (USP37) mediated effects in microscaffold-encapsulated cells: a comprehensive study on growth, proliferation and EMT
   RSC Adv (2024) 14, 5461-5471. PubMed  Europe PubMed DOI  PMC  EPMC
8. Li,Y., Wang,W., Sun,L., Huang,J., Ma,X., Li,S. and Shi,X.
   USP37 promotes diffuse large B-cell lymphoma progression by deubiquitinating and stabilizing c-myc
   J Mol Histol (2024) 56, 54-54. PubMed  Europe PubMed DOI
9. Wu,J., Chen,Y., Li,R., Guan,Y., Chen,M., Yin,H., Yang,X., Jin,M., Huang,B., Ding,X., Yang,J., Wang,Z., He,Y., Wang,Q., Luo,J., Wang,P., Mao,Z., Huen,M.S.Y., Lou,Z., Yuan,J. and Gong,F.
   Synergistic anticancer effect by targeting CDK2 and EGFR-ERK signaling
   J Cell Biol (2024) 223 PubMed  Europe PubMed DOI  PMC  EPMC
2023
10. 
    Expression of Concern: The HBx Oncoprotein of Hepatitis B Virus Deregulates the Cell Cycle by Promoting the Intracellular Accumulation and Re-Compartmentalization of the Cellular Deubiquitinase USP37
    PLoS ONE (2023) 18, e0293102-e0293102. PubMed  Europe PubMed DOI  PMC  EPMC
11. Chauhan,R., Gupta,A., Malhotra,L., Bhat,A.A., Pandita,R.K., Masoodi,T., Dagar,G., Sadida,H.Q., Al-Marzooqi,S.K., Batra,A., Bakhshi,S., Sharma,M.C., Tanwar,P., Khan,S.A., Samath,E.A., Uddin,S., Akil,A.S.A., Haris,M., Macha,M.A., Pandita,T.K. and Singh,M.
    Ubiquitin specific peptidase 37 and PCNA interaction promotes osteosarcoma pathogenesis by modulating replication fork progression
    J Transl Med (2023) 21, 286-286. PubMed  Europe PubMed DOI  PMC  EPMC  K
12. Kamran,D.E.S., Hussain,M. and Mirza,T.
    Investigating In Situ Expression of c-MYC and Candidate Ubiquitin-Specific Proteases in DLBCL and Assessment for Peptidyl Disruptor Molecule against c-MYC-USP37 Complex
    Molecules (2023) 28 PubMed  Europe PubMed DOI  PMC  EPMC
13. Tong,D., Yuan,J., Wang,Z., Yu,E. and E,J.
    USP37 promotes angiogenesis and metastasis in colorectal cancer by facilitating beta-catenin stability
    Am J Cancer Res (2023) 13, 2323-2341. PubMed  Europe PubMed  PMC  EPMC
2022
14. Kim,S.Y., Lee,J.Y., Cho,Y.J., Jo,K.H., Kim,E.S., Han,J.H., Baek,K.H. and Moon,S.D.
    USP37 Deubiquitinates CDC73 in HPT-JT Syndrome
    Int J Mol Sci (2022) 23 PubMed  Europe PubMed DOI  PMC  EPMC
15. Piao,M. and Feng,G.
    The deubiquitinating enzyme USP37 promotes keloid fibroblasts proliferation and collagen production by regulating the c-Myc expression
    Int Wound J (2022) PubMed  Europe PubMed DOI
16. Qin,S., Yuan,Y., Huang,X., Tan,Z., Hu,X., Liu,H., Pu,Y., Ding,Y.Q., Su,Z. and He,C.
    Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37
    Nucleic Acids Res (2022) 50, 9319-9338. PubMed  Europe PubMed DOI  PMC  EPMC  K
2021
17. Chauhan,R., Bhat,A.A., Masoodi,T., Bagga,P., Reddy,R., Gupta,A., Sheikh,Z.A., Macha,M.A., Haris,M. and Singh,M.
    Ubiquitin-specific peptidase 37: an important cog in the oncogenic machinery of cancerous cells
    J Exp Clin Cancer Res (2021) 40, 356-356. PubMed  Europe PubMed DOI  PMC  EPMC
18. Kim,M.S., Kim,S.H., Yang,S.H. and Kim,M.S.
    miR-4487 Enhances Gefitinib-Mediated Ubiquitination and Autophagic Degradation of EGFR in Non-Small Cell Lung Cancer Cells by Targeting USP37
    Cancer Res Treat (2021) PubMed  Europe PubMed DOI
19. Li,W., Huang,K., Wen,F., Cui,G., Guo,H., He,Z. and Zhao,S.
    Intermittent hypoxia-induced downregulation of microRNA-320b promotes lung cancer tumorigenesis by increasing CDT1 via USP37
    Mol Ther Nucleic Acids (2021) 24, 528-541. PubMed  Europe PubMed DOI  PMC  EPMC
20. Qin,T., Cui,X.Y., Xiu,H., Huang,C., Sun,Z.N., Xu,X.M., Li,L.H. and Yue,L.
    USP37 downregulation elevates the Chemical Sensitivity of Human Breast Cancer Cells to Adriamycin
    Int J Med Sci (2021) 18, 325-334. PubMed  Europe PubMed DOI  PMC  EPMC  K
21. Stromberg,B.R., Singh,M., Torres,A.E., Burrows,A.C., Pal,D., Insinna,C., Rhee,Y., Dickson,A.S., Westlake,C.J. and Summers,M.K.
    The deubiquitinating enzyme USP37 enhances CHK1 activity to promote the cellular response to replication stress
    J Biol Chem (2021) 297, 101184-101184. PubMed  Europe PubMed DOI  PMC  EPMC
22. Wu,C., Chang,Y., Chen,J., Su,Y., Li,L., Chen,Y., Li,Y., Wu,J., Huang,J., Zhao,F., Wang,W., Yin,H., Wang,S., Jin,M., Lou,Z., Zhu,W.G., Luo,K., Zhang,J. and Yuan,J.
    USP37 regulates DNA damage response through stabilizing and deubiquitinating BLM
    Nucleic Acids Res (2021) 49, 11224-11240. PubMed  Europe PubMed DOI  PMC  EPMC  K
23. Wu,L., Zhao,N., Zhou,Z., Chen,J., Han,S., Zhang,X., Bao,H., Yuan,W. and Shu,X.
    PLAGL2 promotes the proliferation and migration of gastric cancer cells via USP37-mediated deubiquitination of Snail1
    Theranostics (2021) 11, 700-714. PubMed  Europe PubMed DOI  PMC  EPMC
2020
24. Hong,K., Hu,L., Liu,X., Simon,J.M., Ptacek,T.S., Zheng,X., Liao,C., Baldwin,A.S. and Zhang,Q.
    USP37 promotes deubiquitination of HIF2alpha in kidney cancer
    Proc Natl Acad Sci U S A (2020) PubMed  Europe PubMed DOI
2019
25. Cai,J., Li,M., Wang,X., Li,L., Li,Q., Hou,Z., Jia,H. and Liu,S.
    USP37 Promotes lung cancer cell migration by stabilizing snail protein via deubiquitination
    Front Genet (2019) 10, 1324-1324. PubMed  Europe PubMed DOI  PMC  EPMC
26. Manczyk,N., Veggiani,G., Teyra,J., Strilchuk,A.W., Sidhu,S.S. and Sicheri,F.
    The ubiquitin interacting motifs of USP37 act on the proximal Ub of a di-Ub chain to enhance catalytic efficiency
    Sci Rep (2019) 9, 4119-4119. PubMed  Europe PubMed DOI
27. Xiao,Z., Chang,L., Kim,J., Zhang,P., Hang,Q., Yap,S., Guo,Y., Zhou,Z., Zeng,L., Hu,X., Siverly,A., Sun,Y. and Ma,L.
    USP37 is a SNAI1 deubiquitinase
    Am J Cancer Res (2019) 9, 2749-2759. PubMed  Europe PubMed  PMC  EPMC
2016
28. Hernandez-Perez,S., Cabrera,E., Amoedo,H., Rodriguez-Acebes,S., Koundrioukoff,S., Debatisse,M., Mendez,J. and Freire,R.
    USP37 deubiquitinates Cdt1 and contributes to regulate DNA replication
    Mol Oncol (2016) 10, 1196-1206. PubMed  Europe PubMed DOI
2015
29. Pan,J., Deng,Q., Jiang,C., Wang,X., Niu,T., Li,H., Chen,T., Jin,J., Pan,W., Cai,X., Yang,X., Lu,M., Xiao,J. and Wang,P.
    USP37 directly deubiquitinates and stabilizes c-Myc in lung cancer
    Oncogene (2015) 34, 3957-3967. PubMed  Europe PubMed DOI
30. Sun,X.X., Sears,R.C. and Dai,M.S.
    Deubiquitinating c-Myc: USP36 steps up in the nucleolus
    Cell Cycle (2015) 14, 3786-3793. PubMed  Europe PubMed DOI
31. Typas,D., Luijsterburg,M.S., Wiegant,W.W., Diakatou,M., Helfricht,A., Thijssen,P.E., van de Broek,B., Mullenders,L.H. and van Attikum,H.
    The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80
    Nucleic Acids Res (2015) 43, 6919-6933. PubMed  Europe PubMed DOI
32. Yeh,C., Coyaud,E., Bashkurov,M., van der Lelij,P., Cheung,S.W., Peters,J.M., Raught,B. and Pelletier,L.
    The deubiquitinase USP37 regulates chromosome cohesion and mitotic progression
    Curr Biol (2015) 25, 2290-2299. PubMed  Europe PubMed DOI
2014
33. Saxena,N. and Kumar,V.
    The HBx oncoprotein of hepatitis B virus deregulates the cell cycle by promoting the intracellular accumulation and re-compartmentalization of the cellular deubiquitinase USP37
    PLoS ONE (2014) 9, e111256-e111256. PubMed  Europe PubMed DOI  PMC  EPMC
34. Tanno,H., Shigematsu,T., Nishikawa,S., Hayakawa,A., Denda,K., Tanaka,T. and Komada,M.
    Ubiquitin-interacting motifs confer full catalytic activity, but not ubiquitin chain substrate specificity, to deubiquitinating enzyme USP37
    J Biol Chem (2014) 289, 2415-2423. PubMed  Europe PubMed DOI
2013
35. Yang,W.C. and Shih,H.M.
    The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/RARA stability
    Oncogene (2013) 32, 5167-5175. PubMed  Europe PubMed DOI
2012
36. Burrows,A.C., Prokop,J. and Summers,M.K.
    Skp1-Cul1-F-box ubiquitin ligase (SCF (betaTrCP))-mediated destruction of the ubiquitin-specific protease USP37 during G2-phase promotes mitotic entry
    J Biol Chem (2012) 287, 39021-39029. PubMed  Europe PubMed DOI
2011
37. Huang,X., Summers,M.K., Pham,V., Lill,J.R., Liu,J., Lee,G., Kirkpatrick,D.S., Jackson,P.K., Fang,G. and Dixit,V.M.
    Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry
    Mol Cell (2011) 42, 511-523. PubMed  Europe PubMed DOI
38. Yu,H.
    Tango between ubiquitin ligase and deubiquitinase keeps cyclin A tag free
    Mol Cell (2011) 42, 409-410. PubMed  Europe PubMed DOI
2004
39. [YEAR:30-1-2004]Quesada,V., Diaz-Perales,A., Gutierrez-Fernandez,A., Garabaya,C., Cal,S. and Lopez-Otin,C.
    Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases
    Biochem Biophys Res Commun (30-1-2004) 314, 54-62. PubMed  Europe PubMed DOI
2003
40. Puente,X.S., Sanchez,L.M., Overall,C.M. and Lopez-Otin,C.
    Human and mouse proteases: a comparative genomic approach
    Nat Rev Genet (2003) 4, 544-558. PubMed  Europe PubMed DOI