Literature for peptidase C19.048: ubiquitin-specific peptidase 42

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: M Mutation, K Knockout. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. He,C., Chen,J., Tian,R., Yang,L., He,W., He,L., Xu,J., Li,J., Wang,G., Jiang,C., Liu,Q., Wan,X. and Yu,T.
    Deubiquitinating enzyme USP42 promotes breast cancer progression by inhibiting JNK/p38-mediated apoptosis
    Sci Rep (2025) 15, 36751-36751. PubMed  Europe PubMed DOI  PMC  EPMC  K
  2. Yang,N., Tian,Q., Lei,Z., Wang,S., Cheng,N., Wang,Z., Jiang,X., Zheng,X., Xu,W., Ye,M., Zhao,L., Wen,M., Niu,J., Sun,W., Shen,P., Huang,Z. and Li,X.
    FGF2 Mediated USP42-PPARgamma Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration
    Adv Sci (Weinh) (2025) , e2408724-e2408724. PubMed  Europe PubMed DOI
  3. 2024
  4. Pan,Y., Gu,H., Xiao,H., Zhao,L., Tang,Y. and Ge,W.
    [Ubiquitin-specific protease 42 regulates osteogenic differentiation of human adipose-derived stem cells]
    Beijing Da Xue Xue Bao Yi Xue Ban (2024) 56, 9-16. PubMed  Europe PubMed DOI  PMC  EPMC  K
  5. 2022
  6. Mishra,R., Kumawat,K.L., Basu,A. and Banerjea,A.C.
    Japanese Encephalitis Virus infection increases USP42 to stabilize TRIM21 and OAS1 for neuroinflammatory and anti-viral response in human microglia
    Virology (2022) 573, 131-140. PubMed  Europe PubMed DOI
  7. 2021
  8. Giebel,N., de Jaime-Soguero,A., Garcia Del Arco,A., Landry,J.J.M., Tietje,M., Villacorta,L., Benes,V., Fernandez-Saiz,V. and Acebron,S.P.
    USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling
    EMBO Rep (2021) 22, e51415-e51415. PubMed  Europe PubMed DOI
  9. Uriarte,M., Milot,E. and Affar,E.B.
    USP42 deubiquitinase in the arena of liquid-liquid phase separation and nuclear speckles
    Cell Death Differ (2021) 28, 2022-2024. PubMed  Europe PubMed DOI  PMC  EPMC
  10. 2016
  11. Hou,K., Zhu,Z., Wang,Y., Zhang,C., Yu,S., Zhu,Q. and Yan,B.
    Overexpression and biological function of ubiquitin-specific protease 42 in gastric cancer
    PLoS ONE (2016) 11, e0152997-e0152997. PubMed  Europe PubMed DOI
  12. 2014
  13. Hock,A.K., Vigneron,A.M. and Vousden,K.H.
    Ubiquitin-specific peptidase 42 (USP42) functions to deubiquitylate histones and regulate transcriptional activity
    J Biol Chem (2014) 289, 34862-34870. PubMed  Europe PubMed DOI
  14. 2011
  15. Hock,A.K., Vigneron,A.M., Carter,S., Ludwig,R.L. and Vousden,K.H.
    Regulation of p53 stability and function by the deubiquitinating enzyme USP42
    EMBO J (2011) 30, 4921-4930. PubMed  Europe PubMed DOI
  16. 2007
  17. Kim,Y.K., Kim,Y.S., Yoo,K.J., Lee,H.J., Lee,D.R., Yeo,C.Y. and Baek,K.H.
    The expression of Usp42 during embryogenesis and spermatogenesis in mouse
    Gene Expr Patterns (2007) 7, 143-148. PubMed  Europe PubMed DOI
  18. 2006
  19. [YEAR:15-12-2006]Paulsson,K., Bekassy,A.N., Olofsson,T., Mitelman,F., Johansson,B. and Panagopoulos,I.
    A novel and cytogenetically cryptic t(7;21)(p22;q22) in acute myeloid leukemia results in fusion of RUNX1 with the ubiquitin-specific protease gene USP42
    Leukemia (15-12-2006) 20, 224-229. PubMed  Europe PubMed DOI  M
  20. 2004
  21. [YEAR:30-1-2004]Quesada,V., Diaz-Perales,A., Gutierrez-Fernandez,A., Garabaya,C., Cal,S. and Lopez-Otin,C.
    Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases
    Biochem Biophys Res Commun (30-1-2004) 314, 54-62. PubMed  Europe PubMed DOI
  22. 2003
  23. Puente,X.S., Sanchez,L.M., Overall,C.M. and Lopez-Otin,C.
    Human and mouse proteases: a comparative genomic approach
    Nat Rev Genet (2003) 4, 544-558. PubMed  Europe PubMed DOI