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Literature for peptidase C19.047: ubiquitin-specific peptidase 24

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

(Topics flags: M Mutation, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Shan,H., Yuan,J., Xian,L., Li,W., Ge,Y., Zhang,L., Lin,T., Lan,M., Liu,J., Luo,Y., Wu,Y. and Xiao,X.
    USP24 promotes hepatocellular carcinoma progression by deubiquitinating and stabilizing YAP1
    Cancer Cell Int (2025) 25, 164-164. PubMed  Europe PubMed DOI  PMC  EPMC  K
  2. Ye,L., Du,Y., Mai,Y., Hu,T. and Chen,P.
    Ubiquitin-specific protease 24: a potential anti-cancer target
    Biochem Biophys Res Commun (2025) 790, 152895-152895. PubMed  Europe PubMed DOI
    3. 2024
  3. Cao,J., Wu,S., Zhao,S., Wang,L., Wu,Y., Song,L., Sun,C., Liu,Y., Liu,Z., Zhu,R., Liang,R., Wang,W. and Sun,Y.
    USP24 promotes autophagy-dependent ferroptosis in hepatocellular carcinoma by reducing the K48-linked ubiquitination of Beclin1
    Commun Biol (2024) 7, 1279-1279. PubMed  Europe PubMed DOI  PMC  EPMC
  4. Song,X., Xia,B., Gao,X., Liu,X., Lv,H., Wang,S., Xiao,Q. and Luo,H.
    Related cellular signaling and consequent pathophysiological outcomes of ubiquitin specific protease 24
    Life Sci (2024) 342, 122512-122512. PubMed  Europe PubMed DOI  V
  5. Wu,S., Zhou,Y., Liang,J., Ying,P., Situ,Q., Tan,X. and Zhu,J.
    Upregulation of NF-kappaB by USP24 aggravates ferroptosis in diabetic cardiomyopathy
    Free Radic Biol Med (2024) 210, 352-366. PubMed  Europe PubMed DOI  K
    6. 2023
  6. Li,X., Zhang,J., Wang,B., Chen,C., Zhang,E., Lv,Z., He,Q., Hu,Y., Wang,X. and Zhang,F.
    USP24-dependent stabilization of Runx2 recruits a p300/NCOA3 complex to transactivate ADAMTS genes and promote degeneration of intervertebral disc in chronic inflammation mice
    Biol Direct (2023) 18, 37-37. PubMed  Europe PubMed DOI  PMC  EPMC
  7. Liu,N., Lin,M.M. and Wang,Y.
    The Emerging Roles of E3 Ligases and DUBs in Neurodegenerative Diseases
    Mol Neurobiol (2023) 60, 247-263. PubMed  Europe PubMed DOI  PMC  EPMC  V
  8. Zang,L., Gu,J., Yang,X., Yuan,Y., Guo,H., Zhou,W., Ma,J., Chen,Y., Wu,Y., Zheng,H. and Shi,W.
    Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1
    Virol Sin (2023) 38, 75-83. PubMed  Europe PubMed DOI  PMC  EPMC  K
  9. Zhi,X., Jiang,S., Zhang,J. and Qin,J.
    Ubiquitin-specific peptidase 24 accelerates aerobic glycolysis and tumor progression in gastric carcinoma through stabilizing PLK1 to activate NOTCH1
    Cancer Sci (2023) 114, 3087-3100. PubMed  Europe PubMed DOI  PMC  EPMC
    10. 2020
  10. Bedekovics,T., Hussain,S., Zhang,Y., Ali,A., Jeon,Y.J. and Galardy,P.J.
    USP24 is a cancer-associated ubiquitin hydrolase, novel tumor suppressor, and chromosome instability gene deleted in neuroblastoma
    Cancer Res (2020) PubMed  Europe PubMed DOI
  11. Thayer,J.A., Awad,O., Hegdekar,N., Sarkar,C., Tesfay,H., Burt,C., Zeng,X., Feldman,R.A. and Lipinski,M.M.
    The PARK10 gene USP24 is a negative regulator of autophagy and ULK1 protein stability
    Autophagy (2020) 16, 140-153. PubMed  Europe PubMed DOI
  12. Wang,S.A., Young,M.J., Jeng,W.Y., Liu,C.Y. and Hung,J.J.
    USP24 stabilizes bromodomain containing proteins to promote lung cancer malignancy
    Sci Rep (2020) 10, 20870-20870. PubMed  Europe PubMed DOI  PMC  EPMC
    13. 2019
  13. Luo,H., Jing,B., Xia,Y., Zhang,Y., Hu,M., Cai,H., Tong,Y., Zhou,L., Yang,L., Yang,J., Lei,H., Xu,H., Liu,C. and Wu,Y.
    WP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia
    Cancer Cell Int (2019) 19, 56-56. PubMed  Europe PubMed DOI  PMC  EPMC  I
    14. 2018
  14. Sun,Y., Bao,Q., Xuan,B., Xu,W., Pan,D., Li,Q. and Qian,Z.
    Human Cytomegalovirus Protein pUL38 Prevents Premature Cell Death by Binding to Ubiquitin-specific Protease 24 and Regulating Iron Metabolism
    J Virol (2018) 92, e00191-18-e00191-18. PubMed  Europe PubMed DOI
    15. 2017
  15. Wang,S.A., Wang,Y.C., Chuang,Y.P., Huang,Y.H., Su,W.C., Chang,W.C. and Hung,J.J.
    EGF-mediated inhibition of ubiquitin-specific peptidase 24 expression has a crucial role in tumorigenesis
    Oncogene (2017) 36, 2930-2945. PubMed  Europe PubMed DOI
    16. 2016
  16. Wang,Y.C., Wang,S.A., Chen,P.H., Hsu,T.I., Yang,W.B., Chuang,Y.P., Su,W.C., Liaw,H.J., Chang,W.C. and Hung,J.J.
    Variants of ubiquitin-specific peptidase 24 play a crucial role in lung cancer malignancy
    Oncogene (2016) 35, 3669-3680. PubMed  Europe PubMed DOI  M
  17. Zhang,L. and Gong,F.
    Involvement of USP24 in the DNA damage response
    Mol Cell Oncol (2016) 3, e1011888-e1011888. PubMed  Europe PubMed DOI  PMC  EPMC
    18. 2015
  18. Peterson,L.F., Sun,H., Liu,Y., Potu,H., Kandarpa,M., Ermann,M., Courtney,S.M., Young,M., Showalter,H.D., Sun,D., Jakubowiak,A., Malek,S.N., Talpaz,M. and Donato,N.J.
    Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies
    Blood (2015) 125, 3588-3597. PubMed  Europe PubMed DOI  I
  19. Zhang,L., Nemzow,L., Chen,H., Lubin,A., Rong,X., Sun,Z., Harris,T.K. and Gong,F.
    The deubiquitinating enzyme USP24 is a regulator of the UV damage response
    Cell Rep (2015) 10, 140-147. PubMed  Europe PubMed DOI
    20. 2012
  20. Zhang,L., Lubin,A., Chen,H., Sun,Z. and Gong,F.
    The deubiquitinating protein USP24 interacts with DDB2 and regulates DDB2 stability
    Cell Cycle (2012) 11, 4378-4384. PubMed  Europe PubMed DOI
    21. 2010
  21. Wu,Y.R., Chen,C.M., Chen,Y.C., Chao,C.Y., Ro,L.S., Fung,H.C., Hsiao,Y.C., Hu,F.J. and Lee-Chen,G.J.
    Ubiquitin specific proteases USP24 and USP40 and ubiquitin thiolesterase UCHL1 polymorphisms have synergic effect on the risk of Parkinson's disease among Taiwanese
    Clin Chim Acta (2010) 411, 955-958. PubMed  Europe PubMed DOI  M
    22. 2009
  22. Haugarvoll,K., Toft,M., Skipper,L., Heckman,M.G., Crook,J.E., Soto,A., Ross,O.A., Hulihan,M.M., Kachergus,J.M., Sando,S.B., White,L.R., Lynch,T., Gibson,J.M., Uitti,R.J., Wszolek,Z.K., Aasly,J.O. and Farrer,M.J.
    Fine-mapping and candidate gene investigation within the PARK10 locus
    Eur J Hum Genet (2009) 17, 336-343. PubMed  Europe PubMed DOI  M
    23. 2006
  23. [YEAR:17-8-2006]Li,Y., Schrodi,S., Rowland,C., Tacey,K., Catanese,J. and Grupe,A.
    Genetic evidence for ubiquitin-specific proteases USP24 and USP40 as candidate genes for late-onset Parkinson disease
    Hum Mutat (17-8-2006) 27, 1017-1023. PubMed  Europe PubMed DOI  M
    24. 2005
  24. Oliveira,S.A., Li,Y.J., Noureddine,M.A., Zuchner,S., Qin,X., Pericak-Vance,M.A. and Vance,J.M.
    Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease
    Am J Hum Genet (2005) 77, 252-264. PubMed  Europe PubMed DOI  PMC  EPMC

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