Literature for peptidase C19.023: ubiquitin-specific peptidase 17

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

(Topics flags: K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Xue,Y., Xue,C. and Song,W.
    Emerging roles of deubiquitinating enzymes in actin cytoskeleton and tumor metastasis
    Cell Oncol (Dordr) PubMed  Europe PubMed DOI  V
  2. 2022
  3. Lata,S., Sood,V. and Banerjea,A.C.
    Human Immunodeficiency Virus Type 1 Vif Up-Regulates the Expression of Tat via AKT Signaling Pathway: Role of Ubiquitin Specific Protease 17
    Front Microbiol13, 828430-828430. PubMed  Europe PubMed DOI
  4. Nagasaka,M., Inoue,Y., Yoshida,M., Miyajima,C., Morishita,D., Tokugawa,M., Nakamoto,H., Sugano,M., Ohoka,N. and Hayashi,H.
    The deubiquitinating enzyme USP17 regulates c-Myc levels and controls cell proliferation and glycolysis
    FEBS Lett596, 465-478. PubMed  Europe PubMed DOI  K
  5. 2020
  6. Ducker,C. and Shaw,P.E.
    USP17-mediated de-ubiquitination and cancer: Clients cluster around the cell cycle
    Int J Biochem Cell Biol130, 105886-105886. PubMed  Europe PubMed DOI  V
  7. Feng,L., Zhang,J., Sun,M., Qiu,F., Chen,W. and Qiu,W.
    Tumor Suppressor LINC02487 Inhibits Oral Squamous Cell Carcinoma Cell Migration and Invasion Through the USP17-SNAI1 Axis
    Front Oncol10, 559808-559808. PubMed  Europe PubMed DOI
  8. Quintero-Barceinas,R.S., Gehringer,F., Ducker,C., Saxton,J. and Shaw,P.E.
    ELK-1 ubiquitination status and transcriptional activity are modulated independently of F-Box protein FBXO25
    J Biol Chem100214-100214. PubMed  Europe PubMed DOI
  9. Rasaei,R., Sarodaya,N., Kim,K.S., Ramakrishna,S. and Hong,S.H.
    Importance of Deubiquitination in Macrophage-Mediated Viral Response and Inflammation
    Int J Mol Sci21, PubMed  Europe PubMed DOI  V
  10. 2019
  11. Akoumianakis,I., Sanna,F., Margaritis,M., Badi,I., Akawi,N., Herdman,L., Coutinho,P., Fagan,H., Antonopoulos,A.S., Oikonomou,E.K., Thomas,S., Chiu,A.P., Chuaiphichai,S., Kotanidis,C.P., Christodoulides,C., Petrou,M., Krasopoulos,G., Sayeed,R., Lv,L., Hale,A., Naeimi Kararoudi,M., McNeill,E., Douglas,G., George,S., Tousoulis,D., Channon,K.M. and Antoniades,C.
    Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17/RAC1-mediated activation of NADPH oxidases
    Sci Transl Med11, PubMed  Europe PubMed DOI
  12. Chen,X., Wang,C., Liao,K., Zhou,S., Cao,L., Chen,J., Xu,C. and Lin,Y.
    USP17 suppresses tumorigenesis and tumor growth through deubiquitinating AEP
    Int J Biol Sci15, 738-748. PubMed  Europe PubMed DOI
  13. Ducker,C., Chow,L.K.Y., Saxton,J., Handwerger,J., McGregor,A., Strahl,T., Layfield,R. and Shaw,P.E.
    De-ubiquitination of ELK-1 by USP17 potentiates mitogenic gene expression and cell proliferation
    Nucleic Acids Res47, 4495-4508. PubMed  Europe PubMed DOI
  14. Fukuura,K., Inoue,Y., Miyajima,C., Watanabe,S., Tokugawa,M., Morishita,D., Ohoka,N., Komada,M. and Hayashi,H.
    The ubiquitin-specific protease USP17 prevents cellular senescence by stabilizing the methyltransferase SET8 and transcriptionally repressing p21
    J Biol Chem294, 16429-16439. PubMed  Europe PubMed DOI
  15. 2018
  16. Lu,C.H., Yeh,D.W., Lai,C.Y., Liu,Y.L., Huang,L.R., Lee,A.Y., Jin,S.C. and Chuang,T.H.
    USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation
    Oncogene37, 6327-6340. PubMed  Europe PubMed DOI
  17. McCann,A.P., Smyth,P., Cogo,F., McDaid,W.J., Jiang,L., Lin,J., Evergren,E., Burden,R.E., Van Schaeybroeck,S., Scott,C.J. and Burrows,J.F.
    USP17 is required for trafficking and oncogenic signaling of mutant EGFR in NSCLC cells
    Cell Commun Signal16, 77-77. PubMed  Europe PubMed DOI
  18. 2016
  19. Hjortland,N.M. and Mesecar,A.D.
    Steady-state kinetic studies reveal that the anti-cancer target ubiquitin-specific protease 17 (USP17) is a highly efficient deubiquitinating enzyme
    Arch Biochem Biophys612, 35-45. PubMed  Europe PubMed DOI
  20. 2015
  21. Ni,Y., Tao,L., Chen,C., Song,H., Li,Z., Gao,Y., Nie,J., Piccioni,M., Shi,G. and Li,B.
    The deubiquitinase USP17 regulates the stability and nuclear function of IL-33
    Int J Mol Sci16, 27956-27966. PubMed  Europe PubMed DOI
  22. Ramakrishna,S., Suresh,B. and Baek,K.
    Biological functions of hyaluronan and cytokine-inducible deubiquitinating enzymes
    Biochim Biophys Acta1855, 83-91. PubMed  Europe PubMed DOI
  23. Song,H., Tao,L., Chen,C., Pan,L., Hao,J., Ni,Y., Li,D., Li,B. and Shi,G.
    USP17-mediated deubiquitination and stabilization of HDAC2 in cigarette smoke extract-induced inflammation
    Int J Clin Exp Pathol8, 10707-10715. PubMed  Europe PubMed
  24. 2014
  25. Han,L., Yang,J., Wang,X., Wu,Q., Yin,S., Li,Z., Zhang,J., Xing,Y., Chen,Z., Tsun,A., Li,D., Piccioni,M., Zhang,Y., Guo,Q., Jiang,L., Bao,L., Lv,L. and Li,B.
    The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor gammat (RORgammat) in Th17 cells
    J Biol Chem289, 25546-25555. PubMed  Europe PubMed DOI
  26. Jaworski,J., de la Vega,M., Fletcher,S.J., McFarlane,C., Greene,M.K., Smyth,A.W., Van Schaeybroeck,S., Johnston,J.A., Scott,C.J., Rappoport,J.Z. and Burrows,J.F.
    USP17 is required for clathrin mediated endocytosis of epidermal growth factor receptor
    Oncotarget5, 6964-6975. PubMed  Europe PubMed
  27. Jaworski,J., Govender,U., McFarlane,C., de la Vega,M., Greene,M.K., Rawlings,N.D., Johnston,J.A., Scott,C.J. and Burrows,J.F.
    A novel RCE1 isoform is required for H-Ras plasma membrane localization and is regulated by USP17
    Biochem J457, 289-300. PubMed  Europe PubMed DOI
  28. 2012
  29. Burrows,J.F., Johnston,J.A. and Scott,C.J.
    USP17-like peptidase/DUB3 peptidase
    [ISSN:978-0-12-407743-0]3, 2100-2103. DOI
  30. 2011
  31. de la Vega,M., Kelvin,A.A., Dunican,D.J., McFarlane,C., Burrows,J.F., Jaworski,J., Stevenson,N.J., Dib,K., Rappoport,J.Z., Scott,C.J., Long,A. and Johnston,J.A.
    The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility
    Nat Commun2, 259-259. PubMed  Europe PubMed DOI
  32. Ramakrishna,S., Suresh,B., Lee,E.J., Lee,H.J., Ahn,W.S. and Baek,K.H.
    Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity
    J Biol Chem286, 10505-10514. PubMed  Europe PubMed DOI
  33. 2010
  34. Burrows,J.F., Scott,C.J. and Johnston,J.A.
    The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster
    BMC Genomics11, 250-250. PubMed  Europe PubMed DOI
  35. de la Vega,M., Burrows,J.F., McFarlane,C., Govender,U., Scott,C.J. and Johnston,J.A.
    The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected
    J Biol Chem285, 12028-12036. PubMed  Europe PubMed DOI
  36. McFarlane,C., Kelvin,A.A., de la Vega,M., Govender,U., Scott,C.J., Burrows,J.F. and Johnston,J.A.
    The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression
    Cancer Res70, 3329-3339. PubMed  Europe PubMed DOI
  37. Ramakrishna,S., Suresh,B., Kang,I.C. and Baek,K.H.
    Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme
    Hybridoma (Larchmt)29, 311-319. PubMed  Europe PubMed DOI
  38. 2009
  39. Burrows,J.F., Kelvin,A.A., McFarlane,C., Burden,R.E., McGrattan,M.J., de la Vega,M., Govender,U., Quinn,D.J., Dib,K., Gadina,M., Scott,C.J. and Johnston,J.A.
    USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity
    J Biol Chem284, 9587-9595. PubMed  Europe PubMed DOI
  40. 2006
  41. Shin,J.M., Yoo,K.J., Kim,M.S., Kim,D. and Baek,K.H.
    Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability
    BMC Genomics7, 292-292. PubMed  Europe PubMed DOI
  42. 2002
  43. Okada,T., Gondo,Y., Goto,J., Kanazawa,I., Hadano,S. and Ikeda,J.E.
    Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene
    Hum Genet110, 302-313. PubMed  Europe PubMed DOI
  44. 2000
  45. [YEAR:1-8-2000]Saitoh,Y., Miyamoto,N., Okada,T., Gondo,Y., Showguchi-Miyata,J., Hadano,S. and Ikeda,J.E.
    The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter
    Genomics67, 291-300. PubMed  Europe PubMed DOI
  46. 1998
  47. Gondo,Y., Okada,T., Matsuyama,N., Saitoh,Y., Yanagisawa,Y. and Ikeda,J.E.
    Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation
    Genomics54, 39-49. PubMed  Europe PubMed DOI
  48. 1997
  49. Kogi,M., Fukushige,S., Lefevre,C., Hadano,S. and Ikeda,J.E.
    A novel tandem repeat sequence located on human chromosome 4p: isolation and characterization
    Genomics42, 278-283. PubMed  Europe PubMed DOI