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Literature for peptidase C19.014: ubiquitin-specific peptidase 11

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Chen,C., Chen,Z., Luo,R., Tu,W., Long,M., Liang,M., Cheng,M., Wang,Z., Huang,K. and Wang,C.
    Endothelial USP11 drives VEGFR2 signaling and angiogenesis via PRDX2/c-MYC axis
    Angiogenesis28, 23-23. PubMed  Europe PubMed DOI
  2. Deng,Z., Zhou,F., Li,M., Jin,W., Yu,J., Wang,G., Qian,K., Ju,L., Zhang,Y., Xiao,Y. and Wang,X.
    DLGAP5 enhances bladder cancer chemoresistance by regulating glycolysis through MYC stabilization
    Theranostics15, 2375-2392. PubMed  Europe PubMed DOI
  3. Gao,B., Jing,Y., Li,X. and Cong,S.
    Ubiquitin specific peptidase 11 knockdown slows Huntington's disease progression via regulating mitochondrial dysfunction and neuronal damage depending on PTEN-mediated AKT pathway
    Mol Med31, 7-7. PubMed  Europe PubMed DOI
  4. Iwase,R., Maisonet,I.J., Lee,K., Buhrlage,S.J. and Cole,P.A.
    Deubiquitinase processing of a non-natural linkage of ubiquitinated-PTEN
    Bioorg Chem157, 108223-108223. PubMed  Europe PubMed DOI
  5. Liu,J.X., Zhang,Y.K., Zhan,W., Xie,J.H., Xu,Q.H., Zhang,J. and Tai,X.
    USP11 promotes autophagy to attenuate LPS-induced oxidative stress in lung epithelial cells by stabilizing FOXO1 levels
    Biochem Biophys Res Commun751, 151368-151368. PubMed  Europe PubMed DOI
  6. Rajkumar,S., Jung,J.H., Kim,J.Y., Karapurkar,J.K., Birappa,G., Gowda,D.A.A., Ajaykumar,C.B., Perumalsamy,H., Suresh,B., Kim,K.S., Hong,S.H. and Ramakrishna,S.
    Loss of Ubiquitin-Specific Protease 11 Mitigates Pulmonary Fibrosis in Human Pluripotent Stem Cell-Derived Alveolar Organoids
    Int J Stem Cells PubMed  Europe PubMed DOI
  7. Sheng,J., Wu,D., Shang,J., Fu,X., Gao,H., Rong,J., Wang,J., Hu,J. and Qi,X.
    Usp11 maintained the survival of marginal zone B cells under ionizing radiation by deubiquitinating DLL1 and JAG2
    Cell Death Dis16, 67-67. PubMed  Europe PubMed DOI
  8. Wang,X., Xie,X., Ni,J.Y., Li,J.Y., Sun,X.A., Xie,H.Y., Yang,N.H., Guo,H.J., Lu,L., Ning,M., Zhou,L., Liu,J., Xu,C., Zhang,W., Wen,Y., Shen,Q., Xu,H. and Lu,L.M.
    USP11 promotes renal tubular cell pyroptosis and fibrosis in UUO mice via inhibiting KLF4 ubiquitin degradation
    Acta Pharmacol Sin46, 159-170. PubMed  Europe PubMed DOI
  9. Yonezawa,T., Rutter,J., Ramabadran,R., Sundaramurthy,V., Datar,G., Slabicki,M. and Goodell,M.A.
    DNMT3A Stability Is Maintained by Ubiquitin-Specific Peptidase 11 (USP11) and Sumoylation Countering Degradation
    bioRxiv PubMed  Europe PubMed DOI
  10. Zhang,T., Liu,Y., Liu,F., Guo,K., Tang,R., Ye,J., Xue,L., Su,Z. and Wu,Z.B.
    X-linked ubiquitin-specific peptidase 11 (USP11) increases susceptibility to Cushing's disease in women
    Acta Neuropathol Commun13, 22-22. PubMed  Europe PubMed DOI  K
    11. 2024
  11. Chen,J., Ning,D., Du,P., Liu,Q., Mo,J., Liang,H., Zhang,W., Zhang,M., Jiang,L., Zhang,B. and Chen,X.
    USP11 potentiates HGF/AKT signaling and drives metastasis in hepatocellular carcinoma
    Oncogene43, 123-135. PubMed  Europe PubMed DOI
  12. Cui,L., Yang,L., Lai,B., Luo,L., Deng,H., Chen,Z. and Wang,Z.
    Integrative and comprehensive pan-cancer analysis of ubiquitin specific peptidase 11 (USP11) as a prognostic and immunological biomarker
    Heliyon10, e34523-e34523. PubMed  Europe PubMed DOI
  13. Ebina,M., Miura,Y. and Sakane,F.
    Ubiquitin-specific peptidase 11 selectively interacts with and deubiquitination-dependently stabilizes diacylglycerol kinase delta to maintain cellular glucose uptake
    Biochim Biophys Acta Mol Cell Res1872, 119883-119883. PubMed  Europe PubMed DOI  K
  14. Ge,C., Huang,M., Han,Y., Shou,C., Li,D. and Zhang,Y.
    Demethyleneberberine Alleviates Pulmonary Fibrosis through Disruption of USP11 Deubiquitinating GREM1
    Pharmaceuticals (Basel)17, PubMed  Europe PubMed DOI
  15. Guo,Y., Cai,C., Zhang,B., Tan,B., Tang,Q., Lei,Z., Qi,X., Chen,J., Zheng,X., Zi,D., Li,S. and Tan,J.
    Targeting USP11 regulation by a novel lithium-organic coordination compound improves neuropathologies and cognitive functions in Alzheimer transgenic mice
    EMBO Mol Med16, 2856-2881. PubMed  Europe PubMed DOI
  16. Kim,W.J., Basit,A. and Lee,J.H.
    USP11 modulates mitotic progression and senescence by regulating the p53-p21 axis through MDM2 deubiquitination
    Biochem Biophys Res Commun726, 150275-150275. PubMed  Europe PubMed DOI
  17. Li,T., Huang,J., Zeng,A., Yu,N. and Long,X.
    Ubiquitin-specific peptidase 11 promotes development of keloid derived fibroblasts by de-ubiquitinating TGF-beta receptorII
    Burns50, 641-652. PubMed  Europe PubMed DOI  K
  18. Liu,Y., Li,D., Zhang,X., Xia,S., Qu,Y., Ling,X., Li,Y., Kong,X., Zhang,L., Cui,C.P. and Li,D.
    A protein sequence-based deep transfer learning framework for identifying human proteome-wide deubiquitinase-substrate interactions
    Nat Commun15, 4519-4519. PubMed  Europe PubMed DOI
  19. Qian,T., Bai,F., Zhang,S., Xu,Y., Wang,Y., Yuan,S., Liu,X., Du,Y., Peng,B., Zhu,W.G., Xu,X. and Pei,X.H.
    USP11 deubiquitinates E-cadherin and maintains luminal fate of mammary tumor cells to suppress breast cancer
    J Biol Chem107768-107768. PubMed  Europe PubMed DOI
  20. Qiao,L., Hu,W., Li,L., Chen,X., Liu,L. and Wang,J.
    USP11 promotes glycolysis by regulating HIF-1alpha stability in hepatocellular carcinoma
    J Cell Mol Med28, e18017-e18017. PubMed  Europe PubMed DOI
  21. Ryu,E., Yoo,J., Kang,M.S., Ha,N.Y., Jang,Y., Kim,J., Kim,Y., Kim,B.G., Kim,S., Myung,K. and Kang,S.
    ATAD5 functions as a regulatory platform for Ub-PCNA deubiquitination
    Proc Natl Acad Sci U S A121, e2315759121-e2315759121. PubMed  Europe PubMed DOI
  22. Tang,Y., Wang,T., Gu,L., Xu,Y., Yang,Z., Zhu,W., Zhang,Q., Luo,J., Cao,J. and Jiao,Y.
    USP11 Exacerbates Radiation-Induced Pneumonitis by Activating Endothelial Cell Inflammatory Response via OTUD5-STING Signaling
    Int J Radiat Oncol Biol Phys119, 1261-1274. PubMed  Europe PubMed DOI  I
  23. Xu,Y., Zeng,J., Liu,K., Li,D., Huang,S., Fu,S., Ye,M., Tao,S. and Wu,J.
    USP11 promotes lipogenesis and tumorigenesis by regulating SREBF1 stability in hepatocellular carcinoma
    Cell Commun Signal22, 550-550. PubMed  Europe PubMed DOI  K
  24. Zhang,N., Wang,Q., Lu,Y., Wang,F. and He,Z.
    The deubiquitinating enzyme USP11 regulates breast cancer progression by stabilizing PGAM5
    Breast Cancer Res26, 135-135. PubMed  Europe PubMed DOI  K
    25. 2023
  25. Boehm,D., Lam,V., Schnolzer,M. and Ott,M.
    The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11
    Cell Rep42, 112234-112234. PubMed  Europe PubMed DOI  K
  26. Deng,T., Xie,L., Xiaofang,C., Zhang,Z., Xiao,Y., Peng,Y., Yin,L., Fu,Y. and Li,X.
    ATM-Mediated translocation of RanBPM regulates DNA damage response by stabilizing p21 in non-small cell lung cancer cells
    Cell Oncol (Dordr) PubMed  Europe PubMed DOI
  27. Duan,J., Huang,D., Liu,C., Lv,Y., Zhang,L., Chang,F., Zeng,X., Li,L., Wang,W. and Shao,G.
    USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1
    Cell Death Dis14, 402-402. PubMed  Europe PubMed DOI
  28. Fang,Y., Zhao,T., Ni,H., Li,Y., Zhu,Y., Gao,R., Zhang,L., Jia,Z. and Chen,G.
    USP11 exacerbates neuronal apoptosis after traumatic brain injury via PKM2-mediated PI3K/AKT signaling pathway
    Brain Res1807, 148321-148321. PubMed  Europe PubMed DOI
  29. Ghoreshi,Z.A., Molaei,H.R. and Arefinia,N.
    The Role of DNA Viruses in Human Cancer
    Cancer Inform22, 11769351231154186-11769351231154186. PubMed  Europe PubMed DOI  V
  30. Maurer,S.K., Mayer,M.P., Ward,S.J., Boudjema,S., Halawa,M., Zhang,J., Caulton,S.G., Emsley,J. and Dreveny,I.
    Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity
    J Biol Chem299, 105300-105300. PubMed  Europe PubMed DOI
  31. Shi,Y., Tao,M., Chen,H., Ma,X., Wang,Y., Hu,Y., Zhou,X., Li,J., Cui,B., Qiu,A., Zhuang,S. and Liu,N.
    Ubiquitin-specific protease 11 promotes partial epithelial-to-mesenchymal transition by deubiquitinating the epidermal growth factor receptor during kidney fibrosis
    Kidney Int103, 544-564. PubMed  Europe PubMed DOI
  32. Zhang,Y., Hailati,J., Ma,X., Midilibieke,H. and Liu,Z.
    Ubiquitin-specific protease 11 Aggravates Ischemia-reperfusion-induced Cardiomyocyte Pyroptosis and Injury by Promoting TRAF3 Deubiquitination
    Balkan Med J40, 205-214. PubMed  Europe PubMed DOI  K
  33. Zhu,J., Sun,R., Sun,K., Yan,C., Jiang,J., Kong,F. and Shi,J.
    The deubiquitinase USP11 ameliorates intervertebral disc degeneration by regulating oxidative stress-induced ferroptosis via deubiquitinating and stabilizing Sirt3
    Redox Biol62, 102707-102707. PubMed  Europe PubMed DOI
    34. 2022
  34. Gao,Y., Chen,B., Wang,R., Xu,A., Wu,L., Lu,H. and Zhao,G.
    Knockdown of RRM1 in tumor cells promotes radio-/chemotherapy induced ferroptosis by regulating p53 ubiquitination and p21-GPX4 signaling axis
    Cell Death Discov8, 343-343. PubMed  Europe PubMed DOI
  35. Guo,T., Tang,H., Yuan,Z., Zhang,E. and Wang,X.
    The Dual Role of USP11 in Cancer
    J Oncol2022, 9963905-9963905. PubMed  Europe PubMed DOI  V
  36. Kaushal,K., Tyagi,A., Karapurkar,J.K., Kim,E.J., Tanguturi,P., Kim,K.S., Jung,H.S. and Ramakrishna,S.
    Genome-Wide CRISPR/Cas9-Based Screening for Deubiquitinase Subfamily Identifies Ubiquitin-Specific Protease 11 as a Novel Regulator of Osteogenic Differentiation
    Int J Mol Sci23, PubMed  Europe PubMed DOI
  37. Li,L., Deng,T., Zhang,L., Wang,Y., Zhou,Y., Liu,Y., Li,H., Dai,J., Yang,Y., Ling,N., Liu,H., Liu,J., Cao,L., Xu,M. and Ye,M.
    ERK-mediated Cytoplasmic Retention of USP11 Contributes to Breast Cancer Cell Proliferation by Stabilizing Cytoplasmic p21
    Int J Biol Sci18, 2568-2582. PubMed  Europe PubMed DOI
  38. Ni,J.Y., Wang,X., Xie,H.Y., Yang,N.H., Li,J.Y., Sun,X.A., Guo,H.J., Zhou,L., Zhang,W., Liu,J. and Lu,L.M.
    Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-beta receptor II
    Acta Pharmacol Sin PubMed  Europe PubMed DOI  K
  39. Paul,B.D.
    DUB'ling down uncovers an X-linked vulnerability in Alzheimer's disease
    Cell185, 3854-3856. PubMed  Europe PubMed DOI
  40. Zhang,W., Li,X., Xu,J., Wang,Y., Xing,Z., Hu,S., Fan,Q., Lu,S., Cheng,J., Gu,J. and Cai,R.
    The RSL3 Induction of KLK Lung Adenocarcinoma Cell Ferroptosis by Inhibition of USP11 Activity and the NRF2-GSH Axis
    Cancers (Basel)14, PubMed  Europe PubMed DOI
    41. 2021
  41. Basic,M., Hertel,A., Bajdzienko,J., Bonn,F., Tellechea,M., Stolz,A., Kern,A., Behl,C. and Bremm,A.
    The deubiquitinase USP11 is a versatile and conserved regulator of autophagy
    J Biol Chem297, 101263-101263. PubMed  Europe PubMed DOI
  42. Jurga,M., Abugable,A.A., Goldman,A.S.H. and El-Khamisy,S.F.
    USP11 controls R-loops by regulating senataxin proteostasis
    Nat Commun12, 5156-5156. PubMed  Europe PubMed DOI
  43. Liu,H., Liu,M., He,B. and Li,Q.
    Inhibition of USP11 sensitizes gastric cancer to chemotherapy via suppressing RhoA and Ras-mediated signaling pathways
    Clin Res Hepatol Gastroenterol101779-101779. PubMed  Europe PubMed DOI  K
  44. Meng,C., Zhan,J., Chen,D., Shao,G., Zhang,H., Gu,W. and Luo,J.
    The deubiquitinase USP11 regulates cell proliferation and ferroptotic cell death via stabilization of NRF2 USP11 deubiquitinates and stabilizes NRF2
    Oncogene PubMed  Europe PubMed DOI
  45. Perry,M., Biegert,M., Kollala,S.S., Mallard,H., Su,G., Kodavati,M., Kreiling,N., Holbrook,A. and Ghosal,G.
    USP11 mediates repair of DNA-protein crosslinks by deubiquitinating SPRTN metalloprotease
    J Biol Chem100396-100396. PubMed  Europe PubMed DOI
  46. Qiao,L., Zhang,Q., Sun,Z., Liu,Q., Wu,Z., Hu,W., Bao,S., Yang,Q. and Liu,L.
    The E2F1/USP11 positive feedback loop promotes hepatocellular carcinoma metastasis and inhibits autophagy by activating ERK/mTOR pathway
    Cancer Lett514, 63-78. PubMed  Europe PubMed DOI
  47. Rong,Y., Fan,J., Ji,C., Wang,Z., Ge,X., Wang,J., Ye,W., Yin,G., Cai,W. and Liu,W.
    USP11 regulates autophagy-dependent ferroptosis after spinal cord ischemia-reperfusion injury by deubiquitinating Beclin 1
    Cell Death Differ PubMed  Europe PubMed DOI
  48. Sun,H., Wang,R., Liu,Y., Mei,H., Liu,X. and Peng,Z.
    USP11 induce resistance to 5-Fluorouracil in Colorectal Cancer through activating autophagy by stabilizing VCP
    J Cancer12, 2317-2325. PubMed  Europe PubMed DOI
  49. Tang,Y., Yuan,Q., Zhao,C., Xu,Y., Zhang,Q., Wang,L., Sun,Z., Cao,J., Luo,J. and Jiao,Y.
    Targeting USP11 may alleviate radiation-induced pulmonary fibrosis by regulating endothelium tight junction
    Int J Radiat Biol1-11. PubMed  Europe PubMed DOI
  50. Yang,H., Park,D., Ryu,J. and Park,T.
    USP11 degrades KLF4 via its deubiquitinase activity in liver diseases
    J Cell Mol Med25, 6976-6987. PubMed  Europe PubMed DOI
  51. Zhang,W., Wang,Z., Cai,G. and Huang,P.
    Circ_DOCK1 regulates USP11 through miR-132-3p to control colorectal cancer progression
    World J Surg Oncol19, 67-67. PubMed  Europe PubMed DOI
  52. Zhang,X., Liu,T., Xu,S., Gao,P., Dong,W., Liu,W., Gao,M., Song,L., Cui,L. and Dong,X.
    A pro-inflammatory mediator USP11 enhances the stability of p53 and inhibits KLF2 in intracerebral hemorrhage
    Mol Ther Methods Clin Dev21, 681-692. PubMed  Europe PubMed DOI  K
    53. 2020
  53. Bai,M., Che,Y., Lu,K. and Fu,L.
    Analysis of deubiquitinase OTUD5 as a biomarker and therapeutic target for cervical cancer by bioinformatic analysis
    PeerJ8, e9146-e9146. PubMed  Europe PubMed DOI
  54. Feng,P., Li,L., Dai,J., Zhou,L., Liu,J., Zhao,J., Li,X., Ling,N., Qiu,S., Zhang,L., Xie,T., Chen,Y., Donovan,M.J., Peng,T., Song,J. and Ye,M.
    The regulation of NONO by USP11 via deubiquitination is linked to the proliferation of melanoma cells
    J Cell Mol Med PubMed  Europe PubMed DOI  K
  55. Huang,D., Liu,C., Sun,X., Sun,X., Qu,Y., Tang,Y., Li,G. and Tong,T.
    CRL4(DCAF8) and USP11 oppositely regulate the stability of myeloid leukemia factors (MLFs)
    Biochem Biophys Res Commun529, 127-132. PubMed  Europe PubMed DOI
    56. 2019
  56. Istomine,R., Alvarez,F., Almadani,Y., Philip,A. and Piccirillo,C.A.
    The deubiquitinating enzyme ubiquitin-specific peptidase 11 potentiates TGF-beta signaling in CD4(+) T Cells to facilitate Foxp3(+) regulatory T and TH17 cell differentiation
    J Immunol203, 2388-2400. PubMed  Europe PubMed DOI
  57. Maupin-Furlow,J.A.
    Putting phage to work in deubiquitinase ligand discovery
    J Biol Chem294, 437-438. PubMed  Europe PubMed DOI
  58. Spiliotopoulos,A., Blokpoel Ferreras,L., Densham,R.M., Caulton,S.G., Maddison,B.C., Morris,J.R., Dixon,J.E., Gough,K.C. and Dreveny,I.
    Discovery of peptide ligands targeting a specific ubiquitin-like domain-binding site in the deubiquitinase USP11
    J Biol Chem294, 424-436. PubMed  Europe PubMed DOI
  59. Sun,H., Ou,B., Zhao,S., Liu,X., Song,L., Liu,X., Wang,R. and Peng,Z.
    USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway
    EBioMedicine48, 236-247. PubMed  Europe PubMed DOI
  60. Ting,X., Xia,L., Yang,J., He,L., Si,W., Shang,Y. and Sun,L.
    USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair
    Nucleic Acids Res47, 9721-9740. PubMed  Europe PubMed DOI
  61. Wang,W., Wang,J., Yan,H., Zhang,K. and Liu,Y.
    Upregulation of USP11 promotes epithelial to mesenchymal transition by deubiquitinating Snail in ovarian cancer
    Oncol Rep41, 1739-1748. PubMed  Europe PubMed DOI
    62. 2018
  62. Stockum,A., Snijders,A.P. and Maertens,G.N.
    USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation
    PLoS ONE13, e0190513-e0190513. PubMed  Europe PubMed DOI
    63. 2017
  63. Zhou,Z., Luo,A., Shrivastava,I., He,M., Huang,Y., Bahar,I., Liu,Z. and Wan,Y.
    Regulation of XIAP turnover reveals a role for USP11 in promotion of tumorigenesis
    EBioMedicine15, 48-61. PubMed  Europe PubMed DOI
    64. 2016
  64. Jacko,A.M., Nan,L., Li,S., Tan,J., Zhao,J., Kass,D.J. and Zhao,Y.
    De-ubiquitinating enzyme, USP11, promotes transforming growth factor beta-1 signaling through stabilization of transforming growth factor beta receptor II
    Cell Death Dis7, e2474-e2474. PubMed  Europe PubMed DOI
  65. Lee,E.W. and Song,J.
    USP11: a key regulator of cIAP2 stability and sensitivity to SMAC mimetics
    Mol Cell Oncol3, e1029829-e1029829. PubMed  Europe PubMed DOI
  66. Lim,K.H., Suresh,B., Park,J.H., Kim,Y.S., Ramakrishna,S. and Baek,K.H.
    Ubiquitin-specific protease 11 functions as a tumor suppressor by modulating Mgl-1 protein to regulate cancer cell growth
    Oncotarget7, 14441-14457. PubMed  Europe PubMed DOI
  67. Xu,Z., Li,X., Chen,J., Zhao,J., Wang,J., Ji,Y., Shen,Y., Han,L., Shi,J. and Zhang,D.
    USP11, deubiquitinating enzyme, associated with neuronal apoptosis following intracerebral hemorrhage
    J Mol Neurosci58, 16-27. PubMed  Europe PubMed DOI
  68. Yu,M., Liu,K., Mao,Z., Luo,J., Gu,W. and Zhao,W.
    USP11 is a Negative Regulator to gammaH2AX Ubiquitylation by RNF8/RNF168
    J Biol Chem291, 959-967. PubMed  Europe PubMed DOI
  69. Zhang,E., Shen,B., Mu,X., Qin,Y., Zhang,F., Liu,Y., Xiao,J., Zhang,P., Wang,C., Tan,M. and Fan,Y.
    Ubiquitin-specific protease 11 (USP11) functions as a tumor suppressor through deubiquitinating and stabilizing VGLL4 protein
    Am J Cancer Res6, 2901-2909. PubMed  Europe PubMed
    70. 2015
  70. Hendriks,I.A., Schimmel,J., Eifler,K., Olsen,J.V. and Vertegaal,A.C.
    Ubiquitin-specific protease 11 (USP11) deubiquitinates hybrid small ubiquitin-like modifier (SUMO)-ubiquitin chains to counteract RING finger protein 4 (RNF4)
    J Biol Chem290, 15526-15537. PubMed  Europe PubMed DOI
  71. Lee,E.W., Seong,D., Seo,J., Jeong,M., Lee,H.K. and Song,J.
    USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics
    Cell Death Differ22, 1463-1476. PubMed  Europe PubMed DOI
  72. Vlasschaert,C., Xia,X., Coulombe,J. and Gray,D.A.
    Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11
    BMC Evol Biol15, 230-230. PubMed  Europe PubMed DOI
    73. 2014
  73. Harper,S., Gratton,H.E., Cornaciu,I., Oberer,M., Scott,D.J., Emsley,J. and Dreveny,I.
    Structure and catalytic regulatory function of ubiquitin specific protease 11 N-terminal and ubiquitin-like domains
    Biochemistry53, 2966-2978. PubMed  Europe PubMed DOI  S
  74. Ke,J.Y., Dai,C.J., Wu,W.L., Gao,J.H., Xia,A.J., Liu,G.P., Lv,K.S. and Wu,C.L.
    USP11 regulates p53 stability by deubiquitinating p53
    J Zhejiang Univ Sci B15, 1032-1038. PubMed  Europe PubMed DOI
  75. Wu,H.C., Lin,Y.C., Liu,C.H., Chung,H.C., Wang,Y.T., Lin,Y.W., Ma,H.I., Tu,P.H., Lawler,S.E. and Chen,R.H.
    USP11 regulates PML stability to control Notch-induced malignancy in brain tumours
    Nat Commun5, 3214-3214. PubMed  Europe PubMed DOI
    76. 2013
  76. Burkhart,R.A., Peng,Y., Norris,Z.A., Tholey,R.M., Talbott,V.A., Liang,Q., Ai,Y., Miller,K., Lal,S., Cozzitorto,J.A., Witkiewicz,A.K., Yeo,C.J., Gehrmann,M., Napper,A., Winter,J.M., Sawicki,J.A., Zhuang,Z. and Brody,J.R.
    Mitoxantrone targets human ubiquitin-specific peptidase 11 (USP11) and is a potent inhibitor of pancreatic cancer cell survival
    Mol Cancer Res11, 901-911. PubMed  Europe PubMed DOI  I
    77. 2012
  77. Al-Salihi,M.A., Herhaus,L., Macartney,T. and Sapkota,G.P.
    USP11 augments TGFbeta signalling by deubiquitylating ALK5
    Open Biol2, 120063-120063. PubMed  Europe PubMed DOI
    78. 2011
  78. Elliott,P.R., Liu,H., Pastok,M.W., Grossmann,G.J., Rigden,D.J., Clague,M.J., Urbe,S. and Barsukov,I.L.
    Structural variability of the ubiquitin specific protease DUSP-UBL double domains
    FEBS Lett585, 3385-3390. PubMed  Europe PubMed DOI  S
  79. Faesen,A.C., Luna-Vargas,M.P., Geurink,P.P., Clerici,M., Merkx,R., van Dijk,W.J., Hameed,D.S., El Oualid,F., Ovaa,H. and Sixma,T.K.
    The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types
    Chem Biol18, 1550-1561. PubMed  Europe PubMed DOI
    80. 2010
  80. Liao,T.L., Wu,C.Y., Su,W.C., Jeng,K.S. and Lai,M.M.
    Ubiquitination and deubiquitination of NP protein regulates influenza A virus RNA replication
    EMBO J29, 3879-3890. PubMed  Europe PubMed DOI
  81. Maertens,G.N., El Messaoudi-Aubert,S., Elderkin,S., Hiom,K. and Peters,G.
    Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor
    EMBO J29, 2553-2565. PubMed  Europe PubMed DOI
  82. Sun,W., Tan,X., Shi,Y., Xu,G., Mao,R., Gu,X., Fan,Y., Yu,Y., Burlingame,S., Zhang,H., Rednam,S.P., Lu,X., Zhang,T., Fu,S., Cao,G., Qin,J. and Yang,J.
    USP11 negatively regulates TNFalpha-induced NF-kappaB activation by targeting on IkappaBalpha
    Cell Signal22, 386-394. PubMed  Europe PubMed DOI
  83. Wiltshire,T.D., Lovejoy,C.A., Wang,T., Xia,F., O'Connor,M.J. and Cortez,D.
    Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair
    J Biol Chem285, 14565-14571. PubMed  Europe PubMed DOI
    84. 2008
  84. Lin,C.H., Chang,H.S. and Yu,W.C.
    USP11 stabilizes HPV-16E7 and further modulates the E7 biological activity
    J Biol Chem283, 15681-15688. PubMed  Europe PubMed DOI
    85. 2002
  85. [YEAR:1-10-2002]Ideguchi,H., Ueda,A., Tanaka,M., Yang,J., Tsuji,T., Ohno,S., Hagiwara,E., Aoki,A. and Ishigatsubo,Y.
    Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM
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