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Literature for peptidase C12.004: ubiquitinyl hydrolase-BAP1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

(Topics flags: S Structure, T Target, M Mutation, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Ali Boubacar,K., Kahalerras,H. and Affar,E.B.
    Regulation of ferroptosis by BAP1
    Cell Death Differ (2026) PubMed  Europe PubMed DOI
  2. Lee,J., Kim,S., Lee,B., Lee,D., Youn,S.Y., Jung,M., Shim,H., Cha,S.S. and Kwon,J.
    Regulation of BAP1 activity by novel cancer-associated glutamate residues through ubiquitin binding and PARylation
    Biochem Biophys Res Commun (2026) 797, 153166-153166. PubMed  Europe PubMed DOI
  3. Samal,D. and Pethe,P.
    Knockdown of histone H2A deubiquitinase BAP1 in human embryonic stem cells restricts their differentiation repertoire but is dispensable for maintaining their undifferentiated state
    Biochem Biophys Res Commun (2026) 799, 153260-153260. PubMed  Europe PubMed DOI  K
  4. van Genugten,J.H.L.T., Fennell,D.A. and Baas,P.
    BAP1-loss in mesothelioma: molecular mechanisms and clinical opportunities
    Oncogene (2026) PubMed  Europe PubMed DOI
  5. Zhang,J., Li,K., Wang,C., Kong,D., Liang,B., Han,L., Liu,B., Wang,K., Wang,P., Zhao,Y., Ma,L. and Peng,J.
    BAP1-mediated stabilization of SUFU enhances E2F1 activity and promotes colorectal tumorigenesis
    Cell Commun Signal (2026) PubMed  Europe PubMed DOI
    6. 2025
  6. Biswas,S., Lee,J.E., Xie,G., Masclef,L., Ren,Z., Cote,J., Affar,E.B., Ge,K. and Kutateladze,T.G.
    Colorectal cancer hot spot mutations attenuate the ASXL-MLL4 interaction
    J Biol Chem (2025) , 108333-108333. PubMed  Europe PubMed DOI
  7. Dong,Z., Sepulveda,H., Arteaga-Vazquez,L.J., Blouin,C., Fernandez,J., Binder,M., Chou,W.C., Tien,H.F., Patnaik,M.M., Faulkner,G.J., Myers,S.A. and Rao,A.
    A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia
    Proc Natl Acad Sci U S A (2025) 122, e2413302121-e2413302121. PubMed  Europe PubMed DOI
  8. Elsayed,A.M., Kittaneh,M., Cebulla,C.M. and Abdel-Rahman,M.H.
    An overview of BAP1 biological functions and current therapeutics
    Biochim Biophys Acta Rev Cancer (2025) 1880, 189267-189267. PubMed  Europe PubMed DOI  V
  9. Elsayed,A.M., Kittaneh,M., Cebulla,C.M. and Abdel-Rahman,M.H.
    Corrigendum to "An overview of BAP1 biological functions and current therapeutics" [BBA - Reviews on Cancer 1880 (2025) 189267]
    Biochim Biophys Acta Rev Cancer (2025) , 189301-189301. PubMed  Europe PubMed DOI
  10. Hsiao,L.C., Puri,S., Sriramoju,M.K., Wang,Y.S., Lee,T.N., Wang,L.H. and Hsu,S.D.
    Characterization of BRCA1-Associated Protein-1 (BAP1) Aggregation Properties Induced by Cancer-Associated Mutations
    Chembiochem (2025) , e202500372-e202500372. PubMed  Europe PubMed DOI
  11. Iwase,R., Maisonet,I.J., Lee,K., Buhrlage,S.J. and Cole,P.A.
    Deubiquitinase processing of a non-natural linkage of ubiquitinated-PTEN
    Bioorg Chem (2025) 157, 108223-108223. PubMed  Europe PubMed DOI
  12. Lee,B., Lee,J. and Kwon,J.
    PARP1 cooperates with ASXL1 to stimulate BAP1 deubiquitinase activity through its DNA-binding domain
    Biochem Biophys Res Commun (2025) 792, 152982-152982. PubMed  Europe PubMed DOI
  13. Reddington,C.J., Walsh,A.R., Kleffmann,T., Gobl,C. and Mace,P.D.
    Unconventional structure and function of PHD domains from additional sex combs-like proteins
    FEBS J (2025) PubMed  Europe PubMed DOI
  14. Salut,N., Gamallat,Y., Seyedi,S., Felipe Lima,J., Ghosh,S. and Bismar,T.A.
    Unraveling the Prognostic Significance of BRCA1-Associated Protein 1 (BAP1) Expression in Advanced and Castrate-Resistant Prostate Cancer
    Biology (Basel) (2025) 14 PubMed  Europe PubMed DOI  PMC  EPMC
  15. Sanchez,A., Zhou,C., Tulaiha,R., Ramirez,F., Wang,L. and Zhang,X.
    CRISPR Screen Identifies BAP1 as a Deubiquitinase Regulating SPIN4 Stability
    Biochemistry (2025) PubMed  Europe PubMed DOI  PMC  EPMC
  16. Shaker,N., Phelps,R., Niedt,G., Sangueza,O., Krishnan,R., Patel,A., Torres-Cabala,C., Aung,P.P., Prieto,V., Dumur,C.I. and Pradhan,D.
    BRCA1-Associated Protein-1 Inactivated Melanoma Arising in a Pre-existing Nevus With ALK Fusion and Low Tumor Mutational Burden
    Am J Dermatopathol (2025) PubMed  Europe PubMed DOI
  17. Yu,L., Zheng,X., Wu,Y. and Ge,K.
    USP14-Dependent IGF1R Aggravates High Glucose-Induced Diabetic Retinopathy by Upregulating BAP1
    Appl Biochem Biotechnol (2025) PubMed  Europe PubMed DOI
    18. 2024
  18. Cai,W., Wu,S., Lin,Z., Ming,X., Yang,X., Yang,M. and Chen,X.
    Hypoxia-induced BAP1 enhances erastin-induced ferroptosis in nasopharyngeal carcinoma by stabilizing H2A
    Cancer Cell Int (2024) 24, 307-307. PubMed  Europe PubMed DOI  PMC  EPMC  K
  19. Chang,H., Li,M., Zhang,L., Li,M., Ong,S.H., Zhang,Z., Zheng,J., Xu,X., Zhang,Y., Wang,J., Liu,X., Li,K., Luo,Y., Wang,H., Miao,Z., Chen,X., Zha,J. and Yu,Y.
    Loss of histone deubiquitinase Bap1 triggers anti-tumor immunity
    Cell Oncol (Dordr) (2024) PubMed  Europe PubMed DOI
  20. Gonzalez-Fernandez,M., Perry,C., Gerhards,N.M., Francica,P. and Rottenberg,S.
    Docetaxel response in BRCA1,p53-deficient mammary tumor cells is affected by Huntingtin and BAP1
    Proc Natl Acad Sci U S A (2024) 121, e2402849121-e2402849121. PubMed  Europe PubMed DOI  PMC  EPMC
  21. Greco,F., D'Andrea,V., Buoso,A., Cea,L., Bernetti,C., Beomonte Zobel,B. and Mallio,C.A.
    Advancements in Radiogenomics for Clear Cell Renal Cell Carcinoma: Understanding the Impact of BAP1 Mutation
    J Clin Med (2024) 13 PubMed  Europe PubMed DOI  PMC  EPMC  V
  22. Kim,S., Lee,E.W., Oh,D.B. and Seo,J.
    BAP1 controls mesenchymal stem cell migration by inhibiting the ERK signaling pathway
    BMB Rep (2024) 57, 250-255. PubMed  Europe PubMed  K
  23. Liu,X., Cui,L., Tao,Y., Xia,S., Hou,J., Cao,X. and Xu,S.
    The deubiquitinase BAP1 and E3 ligase UBE3C sequentially target IRF3 to activate and resolve the antiviral innate immune response
    Cell Rep (2024) 43, 114608-114608. PubMed  Europe PubMed DOI
  24. Repo,P.E., Backlund,M.P., Kivela,T.T. and Turunen,J.A.
    Functional assay for assessment of pathogenicity of BAP1 variants
    Hum Mol Genet (2024) 33, 426-434. PubMed  Europe PubMed DOI  PMC  EPMC
  25. Shenouda,M., Shaikh,A., Deutsch,I., Mitchell,O., Kindler,H.L. and Armato,S.G., III
    Radiomics for differentiation of somatic BAP1 mutation on CT scans of patients with pleural mesothelioma
    J Med Imaging (Bellingham) (2024) 11, 064501-064501. PubMed  Europe PubMed DOI  PMC  EPMC
  26. Wang,J., Wang,M., Wu,S., Zhu,Y., Fan,K., Chen,Y., Xiao,Z., Chen,J., Tu,K., Huang,D., Zhang,Y. and Xu,Q.
    Tumor suppressor BAP1 suppresses disulfidptosis through the regulation of SLC7A11 and NADPH levels
    Oncogenesis (2024) 13, 31-31. PubMed  Europe PubMed DOI  PMC  EPMC
  27. Xie,Z., Lin,H., Huang,Y., Wang,X., Lin,H., Xu,M., Wu,J., Wu,Y., Shen,H., Zhang,Q., Chen,J., Deng,Y., Xu,Z., Chen,Z., Lin,Y., Han,Y., Lin,L., Yan,L., Li,Q., Lin,X. and Chi,P.
    BAP1-mediated MAFF deubiquitylation regulates tumor growth and is associated with adverse outcomes in colorectal cancer
    Eur J Cancer (2024) 210, 114278-114278. PubMed  Europe PubMed DOI  K
  28. Xu,Z., Zhang,N. and Shi,L.
    Potential roles of UCH family deubiquitinases in tumorigenesis and chemical inhibitors developed against them
    Am J Cancer Res (2024) 14, 2666-2694. PubMed  Europe PubMed DOI  PMC  EPMC  V
  29. Yuan,W., Zhang,Q., Zhao,Y., Xia,W., Yin,S., Liang,X., Chen,T., Li,G., Liu,Y., Liu,Z. and Huang,J.
    BAP1 regulates HSF1 activity and cancer immunity in pancreatic cancer
    J Exp Clin Cancer Res (2024) 43, 275-275. PubMed  Europe PubMed DOI  PMC  EPMC
  30. Zhang,Y., Xie,G., Lee,J.E., Zandian,M., Sudarshan,D., Estavoyer,B., Benz,C., Viita,T., Asgaritarghi,G., Lachance,C., Messmer,C., Simonetti,L., Sinha,V.K., Lambert,J.P., Chen,Y.W., Wang,S.P., Ivarsson,Y., Affar,E.B., Cote,J., Ge,K. and Kutateladze,T.G.
    ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers
    Nat Commun (2024) 15, 4883-4883. PubMed  Europe PubMed DOI  PMC  EPMC
    31. 2023
  31. Ge,W., Yu,C., Li,J., Yu,Z., Li,X., Zhang,Y., Liu,C.P., Li,Y., Tian,C., Zhang,X., Li,G., Zhu,B. and Xu,R.M.
    Basis of the H2AK119 specificity of the Polycomb repressive deubiquitinase
    Nature (2023) 616, 176-182. PubMed  Europe PubMed DOI
  32. Gillies,B., Krema,H., Chao,A., Lando,L., Farncombe,K.M., Butler,M., Altomare,F. and Kim,R.H.
    Oncologist-led germline genetic testing for uveal melanoma
    Ophthalmic Genet (2023) 44, 253-261. PubMed  Europe PubMed DOI  V
  33. Kwon,J., Lee,D. and Lee,S.A.
    BAP1 as a guardian of genome stability: implications in human cancer
    Exp Mol Med (2023) 55, 745-754. PubMed  Europe PubMed DOI  PMC  EPMC  V
  34. Lu,W.T., Li,M.R., Yang,Y.B., Sun,Y.Y. and Dong,C.M.
    Research Progress of BAP1 in Structure, Function, and Cancer
    Protein Pept Lett (2023) 30, 552-561. PubMed  Europe PubMed DOI
  35. Luo,S., Gong,J., Zhao,S., Li,M. and Li,R.
    Deubiquitinase BAP1 regulates stability of BRCA1 protein and inactivates the NF-kappaB signaling to protect mice from sepsis-induced acute kidney injury
    Chem Biol Interact (2023) 382, 110621-110621. PubMed  Europe PubMed DOI
  36. Martinez-Fernandez,C., Jha,S., Aliagas,E., Holmberg,C.I., Nadal,E. and Ceron,J.
    BAP1 Malignant Pleural Mesothelioma Mutations in Caenorhabditis elegans Reveal Synthetic Lethality between ubh-4/BAP1 and the Proteasome Subunit rpn-9/PSMD13
    Cells (2023) 12 PubMed  Europe PubMed DOI  PMC  EPMC
  37. Rohatgi,N., Zou,W., Li,Y., Cho,K., Collins,P.L., Tycksen,E., Pandey,G., DeSelm,C.J., Patti,G.J., Dey,A. and Teitelbaum,S.L.
    BAP1 promotes osteoclast function by metabolic reprogramming
    Nat Commun (2023) 14, 5923-5923. PubMed  Europe PubMed DOI  PMC  EPMC
  38. Shi,W., Liu,X., Zhang,G., Ye,L., Zhou,R., Li,Y. and Yu,L.
    [RITA selectively inhibits proliferation of BAP1-deficient cutaneous melanoma cells in vitro]
    Nan Fang Yi Ke Da Xue Xue Bao (2023) 43, 710-717. PubMed  Europe PubMed DOI  PMC  EPMC
  39. Thomas,J.F., Valencia-Sanchez,M.I., Tamburri,S., Gloor,S.L., Rustichelli,S., Godinez-Lopez,V., De Ioannes,P., Lee,R., Abini-Agbomson,S., Gretarsson,K., Burg,J.M., Hickman,A.R., Sun,L., Gopinath,S., Taylor,H.F., Sun,Z.W., Ezell,R.J., Vaidya,A., Meiners,M.J., Cheek,M.A., Rice,W.J., Svetlov,V., Nudler,E., Lu,C., Keogh,M.C., Pasini,D. and Armache,K.J.
    Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1
    Sci Adv (2023) 9, eadg9832-eadg9832. PubMed  Europe PubMed DOI  PMC  EPMC
  40. Zhang,C. and Wu,S.
    BAP1 mutations inhibit the NF-kappaB signaling pathway to induce an immunosuppressive microenvironment in uveal melanoma
    Mol Med (2023) 29, 126-126. PubMed  Europe PubMed DOI  PMC  EPMC
  41. Zhang,X., Cong,X., Jin,X., Liu,Y., Zhang,T., Fan,X., Shi,X., Zhang,X., Wang,X., Yang,Y.G. and Dai,X.
    Deficiency of BAP1 inhibits neuroblastoma tumorigenesis through destabilization of MYCN
    Cell Death Dis (2023) 14, 504-504. PubMed  Europe PubMed DOI  PMC  EPMC  K
    42. 2022
  42. Baqai,U., Purwin,T.J., Bechtel,N., Chua,V., Han,A., Hartsough,E.J., Kuznetsoff,J.N., Harbour,J.W. and Aplin,A.E.
    Multi-omics profiling shows BAP1 loss is associated with upregulated cell adhesion molecules in uveal melanoma
    Mol Cancer Res (2022) 20, 1260-1271. PubMed  Europe PubMed DOI  K
  43. Blatnik,A., Ribnikar,D., Setrajcic Dragos,V., Novakovic,S., Stegel,V., Grcar Kuzmanov,B., Boc,N., Peric,B., Skerl,P., Klancar,G. and Krajc,M.
    BAP1-defficient breast cancer in a patient with BAP1 cancer syndrome
    Breast Cancer (2022) 29, 921-927. PubMed  Europe PubMed DOI
  44. Caporali,S., Butera,A. and Amelio,I.
    BAP1 in cancer: epigenetic stability and genome integrity
    Discov Oncol (2022) 13, 117-117. PubMed  Europe PubMed DOI  PMC  EPMC
  45. Djulbegovic,M.B., Taylor,D.J., Uversky,V.N., Galor,A., Shields,C.L. and Karp,C.L.
    Intrinsic Disorder in BAP1 and Its Association with Uveal Melanoma
    Genes (Basel) (2022) 13 PubMed  Europe PubMed DOI  PMC  EPMC
  46. Estavoyer,B., Messmer,C., Echbicheb,M., Rudd,C.E., Milot,E. and Affar,E.B.
    Mechanisms orchestrating the enzymatic activity and cellular functions of deubiquitinases
    J Biol Chem (2022) 298, 102198-102198. PubMed  Europe PubMed DOI  PMC  EPMC
  47. Han,A., Chua,V., Baqai,U., Purwin,T.J., Bechtel,N., Hunter,E., Tiago,M., Seifert,E., Speicher,D.W., Schug,Z.T., Harbour,J.W. and Aplin,A.E.
    Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma
    Oncogene (2022) 41, 1129-1139. PubMed  Europe PubMed DOI
  48. Husain,S., Mohamed,R., Abd Halim,K.B. and Mohd Mutalip,S.S.
    Homology modeling of human BAP1 and analysis of its binding properties through molecular docking and molecular dynamics simulation
    J Biomol Struct Dyn (2022) , 1-16. PubMed  Europe PubMed DOI
  49. Jeong,J., Jung,I., Kim,J.H., Jeon,S., Hyeon,D.Y., Min,H., Kang,B., Nah,J., Hwang,D., Um,S.J., Ko,M. and Seong,R.H.
    BAP1 shapes the bone marrow niche for lymphopoiesis by fine-tuning epigenetic profiles in endosteal mesenchymal stromal cells
    Cell Death Differ (2022) 29, 2151-2162. PubMed  Europe PubMed DOI
  50. Kang,J.S., Nam,L.B., Yoo,O.K., Lee,K., Suh,Y.A., Kim,D., Kim,W.K., Lim,C.Y., Lee,H. and Keum,Y.S.
    BAP1 Downregulates NRF2 Target Genes and Exerts Anti-Tumorigenic Effects by Deubiquitinating KEAP1 in Lung Adenocarcinoma
    Antioxidants (Basel) (2022) 11 PubMed  Europe PubMed DOI  PMC  EPMC
  51. Kong,Y., Ren,W., Fang,H., Shah,N.A., Shi,Y., You,D., Zhou,C., Jiang,D., Yang,C., Liang,H., Liu,W., Wang,L., Gan,W., Wan,X., Li,F., Li,Z., Chen,C. and Xie,N.
    Histone Deacetylase Inhibitors (HDACi) Promote KLF5 Ubiquitination and Degradation in Basal-like Breast Cancer
    Int J Biol Sci (2022) 18, 2104-2115. PubMed  Europe PubMed DOI  PMC  EPMC
  52. Langbein,L.E., El Hajjar,R., He,S., Sementino,E., Zhong,Z., Jiang,W., Leiby,B.E., Li,L., Uzzo,R.G., Testa,J.R. and Yang,H.
    BAP1 maintains HIF-dependent interferon beta induction to suppress tumor growth in clear cell renal cell carcinoma
    Cancer Lett (2022) 547, 215885-215885. PubMed  Europe PubMed DOI  PMC  EPMC
  53. Langbein,L.E., Sementino,E., Zhong,Z., Jiang,W., Li,L., Testa,J.R. and Yang,H.
    Data supporting the roles of BAP1, STING, and IFN-beta in ISGF3 activation in ccRCC
    Data Brief (2022) 45, 108743-108743. PubMed  Europe PubMed DOI  PMC  EPMC  K
  54. Lee,S.A., Lee,D., Kang,M., Kim,S., Kwon,S.J., Lee,H.S., Seo,H.R., Kaushal,P., Lee,N.S., Kim,H., Lee,C. and Kwon,J.
    BAP1 promotes the repair of UV-induced DNA damage via PARP1-mediated recruitment to damage sites and control of activity and stability
    Cell Death Differ (2022) 29, 2381-2398. PubMed  Europe PubMed DOI
  55. Liu,R.J., Xu,Z.P., Li,S.Y., Yu,J.J., Feng,N.H., Xu,B. and Chen,M.
    BAP1-Related ceRNA (NEAT1/miR-10a-5p/SERPINE1) Promotes Proliferation and Migration of Kidney Cancer Cells
    Front Oncol (2022) 12, 852515-852515. PubMed  Europe PubMed DOI  PMC  EPMC  K
  56. Pandithan,D., Klebe,S., McKavanagh,G., Rawlings,L., Yu,S., Nicholl,J. and Poplawski,N.
    BAP1 Tumour Predisposition Syndrome Due to Whole BAP1 Gene Deletion
    Case Rep Genet (2022) 2022, 5503505-5503505. PubMed  Europe PubMed DOI  PMC  EPMC
  57. Puri,S., Chen,S.N., Chiu,Y.H., Draczkowski,P., Ko,K.T., Yang,T.J., Wang,Y.S., Uchiyama,S. and Hsu,S.D.
    Impacts of Cancer-associated Mutations on the Structure-Activity Relationship of BAP1
    J Mol Biol (2022) 434, 167553-167553. PubMed  Europe PubMed DOI
  58. Seo,S.U., Woo,S.M., Lee,S.G., Kim,M.Y., Lee,H.S., Choi,Y.H., Kim,S.H., Chang,Y.C., Min,K.J. and Kwon,T.K.
    BAP1 phosphorylation-mediated Sp1 stabilization plays a critical role in cathepsin K inhibition-induced C-terminal p53-dependent Bax upregulation
    Redox Biol (2022) 53, 102336-102336. PubMed  Europe PubMed DOI  PMC  EPMC  K
  59. Takagi-Kimura,M., Tada,A., Kijima,T., Kubo,S., Ohmuraya,M. and Yoshikawa,Y.
    BAP1 depletion in human B-lymphoblast cells affects the production of innate immune cytokines and chemokines
    Genes Cells (2022) 27, 731-740. PubMed  Europe PubMed DOI
  60. Tsuboyama,N., Szczepanski,A.P., Zhao,Z. and Wang,L.
    MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer
    Genome Biol (2022) 23, 206-206. PubMed  Europe PubMed DOI  PMC  EPMC
  61. Tsuboyama,N., Wang,R., Szczepanski,A.P., Chen,H., Zhao,Z., Shi,L. and Wang,L.
    Therapeutic targeting of BAP1/ASXL3 sub-complex in ASCL1-dependent small cell lung cancer
    Oncogene (2022) 41, 2152-2162. PubMed  Europe PubMed DOI  PMC  EPMC  I
  62. Wang,T., Zhu,T., Zhang,Y., Bai,J., Xue,Y., Xu,G., Lu,L. and Peng,Q.
    Pan-cancer analysis of the prognostic and immunological role of BRCA1-associated protein 1 gene (BAP1): Friend or foe?
    Gene (2022) 840, 146765-146765. PubMed  Europe PubMed DOI
  63. Yang,T.J., Li,T.N., Huang,R.S., Pan,M.Y., Lin,S.Y., Lin,S., Wu,K.P., Wang,L.H. and Hsu,S.D.
    Tumor suppressor BAP1 nuclear import is governed by transportin-1
    J Cell Biol (2022) 221 PubMed  Europe PubMed DOI  PMC  EPMC
  64. Zhao,J., Wan,X.N., Zhu,J.P., Liu,Q.C. and Gan,L.
    LncRNA NEAT1 promoted MPP+induced ferroptosis via regulating miR1505p/BAP1 pathway in SKNSH cells
    Acta Neurobiol Exp (Wars) (2022) 82, 226-236. PubMed  Europe PubMed DOI  K
  65. Zhao,Z., Rendleman,E.J., Szczepanski,A.P., Morgan,M.A., Wang,L. and Shilatifard,A.
    CARM1-mediated methylation of ASXL2 impairs tumor-suppressive function of MLL3/COMPASS
    Sci Adv (2022) 8, eadd3339-eadd3339. PubMed  Europe PubMed DOI  PMC  EPMC
    66. 2021
  66. Baas,R., der Wal,J.v., Bleijerveld,O.B., van Attikum,H. and Sixma,T.K.
    Proteomic analysis identifies novel binding partners of BAP1
    PLoS ONE (2021) 16, e0257688-e0257688. PubMed  Europe PubMed DOI  PMC  EPMC
  67. Cao,L., Li,R. and Wu,X.
    The Functions and Mechanisms of PR-DUB in Malignancy
    Front Mol Biosci (2021) 8, 657150-657150. PubMed  Europe PubMed DOI  PMC  EPMC  V
  68. Chen,X., Huang,A., Wang,Y., Chen,F., Hu,B., Zhang,X., Sun,Y., Wang,J., Cheng,J., Wang,P., Ji,Y., Qiu,S., Fan,J., Zhou,J. and Yang,X.
    BRCA1-associated protein 1 serves as a tumor suppressor in hepatocellular carcinoma by deubiquitinating and stabilizing PTEN
    Am J Cancer Res (2021) 11, 2044-2061. PubMed  Europe PubMed  PMC  EPMC
  69. Conway,E., Rossi,F., Fernandez-Perez,D., Ponzo,E., Ferrari,K.J., Zanotti,M., Manganaro,D., Rodighiero,S., Tamburri,S. and Pasini,D.
    BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation
    Mol Cell (2021) PubMed  Europe PubMed DOI
  70. Han,A., Purwin,T.J. and Aplin,A.E.
    Roles of the BAP1 tumor suppressor in cell metabolism
    Cancer Res (2021) PubMed  Europe PubMed DOI  V
  71. Ishii,Y., Kolluri,K.K., Pennycuick,A., Zhang,X., Nigro,E., Alrifai,D., Borg,E., Falzon,M., Shah,K., Kumar,N. and Janes,S.M.
    BAP1 and YY1 regulate expression of death receptors in malignant pleural mesothelioma
    J Biol Chem (2021) 297, 101223-101223. PubMed  Europe PubMed DOI  K
  72. Jia,X., Chen,H., Ren,Y., Dejizhuoga, Gesangyuzhen, Gao,N., Feng,H., Huang,W., Liao,Y. and Yu,H.
    BAP1 antagonizes WWP1-mediated transcription factor KLF5 ubiquitination and inhibits autophagy to promote melanoma progression
    Exp Cell Res (2021) , 112506-112506. PubMed  Europe PubMed DOI
  73. Lin,Y.H., Liang,Y., Wang,H., Tung,L.T., Forster,M., Subramani,P.G., Di Noia,J.M., Clare,S., Langlais,D. and Nijnik,A.
    Regulation of B Lymphocyte Development by Histone H2A Deubiquitinase BAP1
    Front Immunol (2021) 12, 626418-626418. PubMed  Europe PubMed DOI  PMC  EPMC
  74. Novelli,F., Bononi,A., Wang,Q., Bai,F., Patergnani,S., Kricek,F., Haglund,E., Suarez,J.S., Tanji,M., Xu,R., Takanishi,Y., Minaai,M., Pastorino,S., Morris,P., Sakamoto,G., Pass,H.I., Barbour,H., Gaudino,G., Giorgi,C., Pinton,P., Onuchic,J.N., Yang,H. and Carbone,M.
    BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene x environment interaction with asbestos
    Proc Natl Acad Sci U S A (2021) 118 PubMed  Europe PubMed DOI  PMC  EPMC
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