Literature for peptidase C04.004: tobacco etch virus NIa peptidase

(Topics flags: S Structure, A Assay, P Specificity, L Localization, E Expression, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Bemelmans,M.P., Wetzel,B.N., Neusius,F.G., Tieves,F., Schwarz,C., Mateljak,I., Swiderek,K., Moliner,V., Alcalde,M. and Sieber,V.
   Engineering the Tobacco Etch Virus Protease toward a Platform for Traceless Cleavage Using Distal Site Prediction and Smart Library Design
   ACS Synth Biol (2025) PubMed  Europe PubMed DOI
2. Davis,S.M., Romig,B.L., Abe,A.A. and Loening,N.M.
   An improved variant of tobacco etch virus (TEV) protease that does not need reducing agents
   Protein Sci (2025) 34, e70049-e70049. PubMed  Europe PubMed DOI  PMC  EPMC
3. Gao,Z., Li,T., Ye,H., Ngai,W.S.C., Wang,H., Chen,P.R. and Wang,J.
   A gasdermin-based life-death evolution system for reprogramming protease specificity
   Nat Chem Biol (2025) PubMed  Europe PubMed DOI
4. Mikolajczyk,B.M., Golinski,A.W. and Hackel,B.J.
   Enzyme-substrate co-display on yeast empowers engineering of tobacco etch virus protease activity
   Protein Eng Des Sel (2025) PubMed  Europe PubMed DOI
5. Shams,R. and Regan,L.
   A New Highly Specific and Soluble Protease for Precise Removal of Nƒ_'Terminal Purification Tags
   ACS Omega (2025) 10, 30354-30364. PubMed  Europe PubMed DOI  PMC  EPMC
2024
6. Beaumont,L.P., Mehalko,J., Johnson,A., Wall,V.E. and Esposito,D.
   Unexpected tobacco etch virus (TEV) protease cleavage of recombinant human proteins
   Protein Expr Purif (2024) 220, 106488-106488. PubMed  Europe PubMed DOI
7. Cui,M., Lee,S., Ban,S.H., Ryu,J.R., Shen,M., Yang,S.H., Kim,J.Y., Choi,S.K., Han,J., Kim,Y., Han,K., Lee,D., Sun,W., Kwon,H.B. and Lee,D.
   A single-component, light-assisted uncaging switch for endoproteolytic release
   Nat Chem Biol (2024) 20, 353-364. PubMed  Europe PubMed DOI
8. Devoy,C., Flores Bueso,Y., Buckley,S., Walker,S. and Tangney,M.
   Synthetic protein protease sensor platform
   Front Bioeng Biotechnol (2024) 12, 1347953-1347953. PubMed  Europe PubMed DOI  PMC  EPMC
9. Golda,M., Hoffka,G., Cherry,S., Tropea,J.E., Lountos,G.T., Waugh,D.S., Wlodawer,A., Tozser,J. and Motyan,J.A.
   P1' specificity of the S219V/R203G mutant tobacco etch virus protease
   Proteins (2024) 92, 1085-1096-1096. PubMed  Europe PubMed DOI
10. Lan,T., Peng,C., Yao,X., Chan,R.S.T., Wei,T., Rupanya,A., Radakovic,A., Wang,S., Chen,S., Lovell,S., Snyder,S.A., Bogyo,M. and Dickinson,B.C.
    Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display
    J Am Chem Soc (2024) 146, 24053-24060. PubMed  Europe PubMed DOI
11. Martinusen,S.G., Slaton,E.W., Nelson,S.E., Pulgar,M.A., Besu,J.T., Simas,C.F. and Denard,C.A.
    Modular and integrative activity reporters enhance biochemical studies in the yeast ER
    Protein Eng Des Sel (2024) 37 PubMed  Europe PubMed DOI  PMC  EPMC
12. Messing,S., Barnhart,K., Drew,M., Granato-Guerrero,N., Grose,C., Higgins,B., Hong,M., Hull,J., Perkins,S., Poon,I., Ramakrishnan,N., Seabolt,A., Taylor,T., Wall,V.E., Wright,N., Gillette,W. and Esposito,D.
    Improvements in large-scale production of Tobacco Etch Virus protease
    Protein Expr Purif (2024) , 106648-106648. PubMed  Europe PubMed DOI
13. Shahriari,M., Shafiee,F., Moazen,F. and Mohammad Sadeghi,H.M.
    Optimization of the Production of Soluble Recombinant TEV Protease in Two E. coli Strains
    Avicenna J Med Biotechnol (2024) 16, 279-283. PubMed  Europe PubMed DOI  PMC  EPMC
14. Sumida,K.H., Nunez-Franco,R., Kalvet,I., Pellock,S.J., Wicky,B.I.M., Milles,L.F., Dauparas,J., Wang,J., Kipnis,Y., Jameson,N., Kang,A., de la Cruz,J., Sankaran,B., Bera,A.K., Jimenez-Oses,G. and Baker,D.
    Improving Protein Expression, Stability, and Function with ProteinMPNN
    J Am Chem Soc (2024) 146, 2054-2061. PubMed  Europe PubMed DOI  PMC  EPMC
15. Wang,J., Xu,Y., Wang,X., Li,J. and Hua,Z.
    Mechanism of Mutation-Induced Effects on the Catalytic Function of TEV Protease: A Molecular Dynamics Study
    Molecules (2024) 29 PubMed  Europe PubMed DOI  PMC  EPMC
16. Wang,Y., Zheng,J., Wen,F., Tu,B. and Cui,L.
    Novel gnd_v2 Fusion Tag and Engineered TEV Protease Enable Efficient Production of Brazzein
    J Microbiol Biotechnol (2024) 34, 1-11. PubMed  Europe PubMed DOI
2023
17. Fourest-Lieuvin,A., Vinit,A., Blot,B., Perrot,A., Denarier,E., Saudou,F. and Arnal,I.
    Controlled Tau Cleavage in Cells Reveals Abnormal Localizations of Tau Fragments
    Neuroscience (2023) 518, 162-177. PubMed  Europe PubMed DOI
18. Meister,S.W., Parks,L., Kolmar,L., Mestre Borras,A., Stahl,S. and Lofblom,J.
    Engineering of TEV protease variants with redesigned substrate specificity
    Biotechnol J (2023) , e2200625-e2200625. PubMed  Europe PubMed DOI
19. Parida,P.P., Saraswathi,D., Mopidevi,S.M.V. and Raran-Kurussi,S.
    Advancing large-scale production of TEV protease through an innovative NT* tag-based fusion construct
    Curr Res Struct Biol (2023) 6, 100106-100106. PubMed  Europe PubMed DOI  PMC  EPMC
20. Winckler,L.I. and Dissmeyer,N.
    TEV protease cleavage in generation of artificial substrate proteins bearing neo-N-termini
    Methods Enzymol (2023) 686, 125-141. PubMed  Europe PubMed DOI
21. Zheng,M. and Gao,J.
    Phage Display of Two Distinct Warheads to Inhibit Challenging Proteins
    ACS Chem Biol (2023) 18, 2259-2266. PubMed  Europe PubMed DOI
2022
22. Enriquez-Flores,S., De la Mora-De la Mora, Flores-Lopez,L.A., Cabrera,N., Fernandez-Lainez,C., Hernandez-Alcantara,G., Guerrero-Beltran,C.E., Lopez-Velazquez,G. and Garcia-Torres,I.
    Improved yield, stability, and cleavage reaction of a novel tobacco etch virus protease mutant
    Appl Microbiol Biotechnol (2022) 106, 1475-1492. PubMed  Europe PubMed DOI  V
23. Paththamperuma,C. and Page,R.C.
    Fluorescence dequenching assay for the activity of TEV protease
    Anal Biochem (2022) 659, 114954-114954. PubMed  Europe PubMed DOI  PMC  EPMC
24. Renna,P., Ripoli,C., Dagliyan,O., Pastore,F., Rinaudo,M., Re,A., Paciello,F. and Grassi,C.
    Engineering a switchable single-chain TEV protease to control protein maturation in living neurons
    Bioeng Transl Med (2022) 7, e10292-e10292. PubMed  Europe PubMed DOI  PMC  EPMC
25. Zlobin,A. and Golovin,A.
    Between Protein Fold and Nucleophile Identity: Multiscale Modeling of the TEV Protease Enzyme-Substrate Complex
    ACS Omega (2022) 7, 40279-40292. PubMed  Europe PubMed DOI  PMC  EPMC
2021
26. Alonso-Gardon,M. and Estevez,R.
    Split-Tobacco Etch Virus (Split-TEV) Method in G Protein-Coupled Receptor Interacting Proteins
    Methods Mol Biol (2021) 2268, 223-232. PubMed  Europe PubMed DOI
27. Bayar,E., Ren,Y., Chen,Y., Hu,Y., Zhang,S., Yu,X. and Fan,J.
    Construction, investigation and application of the TEV protease variants with the improved oxidative stability
    J Microbiol Biotechnol (2021) 31 PubMed  Europe PubMed DOI
28. Denard,C.A., Paresi,C., Yaghi,R., McGinnis,N., Bennett,Z., Yi,L., Georgiou,G. and Iverson,B.L.
    YESS 2.0, a Tunable Platform for Enzyme Evolution, Yields Highly Active TEV Protease Variants
    ACS Synth Biol (2021) 10, 63-71. PubMed  Europe PubMed DOI
2020
29. Brungardt,J., Govind,R. and Trick,H.N.
    A simplified method for producing laboratory grade recombinant TEV protease from E. coli
    Protein Expr Purif (2020) 174, 105662-105662. PubMed  Europe PubMed DOI  E
30. Chen,S., Lovell,S., Lee,S., Fellner,M., Mace,P.D. and Bogyo,M.
    Identification of highly selective covalent inhibitors by phage display
    Nat Biotechnol (2020) PubMed  Europe PubMed DOI
31. Chung,H.K. and Lin,M.Z.
    On the cutting edge: protease-based methods for sensing and controlling cell biology
    Nat Methods (2020) PubMed  Europe PubMed DOI  V
32. Cupo,R.R. and Shorter,J.
    Expression and Purification of Recombinant Skd3 (Human ClpB) Protein and Tobacco Etch Virus (TEV) Protease from Escherichia coli
    Bio Protoc (2020) 10, e3858-e3858. PubMed  Europe PubMed DOI  PMC  EPMC
33. Deng,Y., Shi,S., Zheng,B., Wu,T. and Zheng,P.
    Enzymatic Construction of Protein Polymer/Polyprotein Using OaAEP1 and TEV Protease
    Bio Protoc (2020) 10, e3596-e3596. PubMed  Europe PubMed DOI  PMC  EPMC
34. Holt,B.A. and Kwong,G.A.
    Protease circuits for processing biological information
    Nat Commun (2020) 11, 5021-5021. PubMed  Europe PubMed DOI  PMC  EPMC
35. Lakshmanan,A., Jin,Z., Nety,S.P., Sawyer,D.P., Lee-Gosselin,A., Malounda,D., Swift,M.B., Maresca,D. and Shapiro,M.G.
    Acoustic biosensors for ultrasound imaging of enzyme activity
    Nat Chem Biol (2020) PubMed  Europe PubMed DOI
36. Mohammadian,N., Mohammadian,H., Moazen,F., Pakdel,M.H., Jahanian-Najafabadi,A. and Mir Mohammad Sadeghi,H.
    Optimization of solvent media to solubilize TEV protease using response surface method
    Res Pharm Sci (2020) 15, 331-339. PubMed  Europe PubMed DOI  PMC  EPMC
37. Nam,H., Hwang,B.J., Choi,D.Y., Shin,S. and Choi,M.
    Tobacco etch virus (TEV) protease with multiple mutations to improve solubility and reduce self-cleavage exhibits enhanced enzymatic activity
    FEBS Open Bio (2020) 10, 619-626. PubMed  Europe PubMed DOI  E
38. Norris,J.L., Patel,T., Dasari,A.K.R., Cope,T.A., Lim,K.H. and Hughes,R.M.
    Covalent and non-covalent strategies for the immobilization of Tobacco Etch Virus protease (TEVp) on superparamagnetic nanoparticles
    J Biotechnol (2020) 322, 1-9. PubMed  Europe PubMed DOI
39. Sanchez,M.I. and Ting,A.Y.
    Directed evolution improves the catalytic efficiency of TEV protease
    Nat Methods (2020) 17, 167-174. PubMed  Europe PubMed DOI  L
40. Sanchez,M.I., Nguyen,Q.A., Wang,W., Soltesz,I. and Ting,A.Y.
    Transcriptional readout of neuronal activity via an engineered Ca(2+)-activated protease
    Proc Natl Acad Sci U S A (2020) 117, 33186-33196. PubMed  Europe PubMed DOI
2018
41. Nautiyal,K. and Kuroda,Y.
    A SEP tag enhances the expression, solubility and yield of recombinant TEV protease without altering its activity
    N Biotechnol (2018) 42, 77-84. PubMed  Europe PubMed DOI  E
42. O'Neill,B.K. and Laughlin,S.T.
    Neuronal calcium recording with an engineered TEV protease
    ACS Chem Biol (2018) 13, 1159-1164. PubMed  Europe PubMed DOI
2017
43. Chen,Y., Li,Q., Yang,J. and Xie,H.
    Promoting tag removal of a MBP-fused integral membrane protein by TEV protease
    Appl Biochem Biotechnol (2017) 181, 939-947. PubMed  Europe PubMed DOI
44. Packer,M.S., Rees,H.A. and Liu,D.R.
    Phage-assisted continuous evolution of proteases with altered substrate specificity
    Nat Commun (2017) 8, 956-956. PubMed  Europe PubMed DOI  PMC  EPMC
45. Raran-Kurussi,S., Cherry,S., Zhang,D. and Waugh,D.S.
    Removal of affinity tags with TEV protease
    Methods Mol Biol (2017) 1586, 221-230. PubMed  Europe PubMed DOI
46. Ren,S., Zhu,G. and Du,L.
    Study on the impacts of Co2+ on the tobacco etch virus protease
    Chin J App Eviron Biol (2017) 23, 113-116. DOI
2016
47. Cesaratto,F., Burrone,O.R. and Petris,G.
    Tobacco etch virus protease: a shortcut across biotechnologies
    J Biotechnol (2016) 231, 239-249. PubMed  Europe PubMed DOI
48. He,Y.H., Li,Y.M. and Chen,Y.X.
    Phosphorylation regulates proteolytic efficiency of TEV protease detected by a 5(6)-carboxyfluorescein-pyrene based fluorescent sensor
    Talanta (2016) 150, 340-345. PubMed  Europe PubMed DOI
2015
49. Cesaratto,F., Lopez-Requena,A., Burrone,O.R. and Petris,G.
    Engineered tobacco etch virus (TEV) protease active in the secretory pathway of mammalian cells
    J Biotechnol (2015) 212, 159-166. PubMed  Europe PubMed DOI
50. Gerhardt,K. and Tabor,J.
    Optogenetic regulation of proteolysis using an engineered light-switchable split Tev protease
    Synth Biol : Eng , Evol , Des Conf , SEED (2015) 2, 804-805.
51. Shafee,T., Gatti-Lafranconi,P., Minter,R. and Hollfelder,F.
    Handicap-recover evolution leads to a chemically versatile, nucleophile-permissive protease
    Chembiochem (2015) 16, 1866-1869. PubMed  Europe PubMed DOI
52. Zhu,G.-F., Ren,S.-Y., Xi,L., Du,L.-F. and Zhu,X.-F.
    Temperature induced structural transitions from native to unfolded aggregated states of tobacco etch virus protease
    J Mol Struct (2015) 1082, 80-90. DOI
2014
53. Fang,J., Zou,L., Zhou,X., Cheng,B. and Fan,J.
    Synonymous rare arginine codons and tRNA abundance affect protein production and quality of TEV protease variant
    PLoS ONE (2014) 9, e112254-e112254. PubMed  Europe PubMed DOI  E
2013
54. Fang,J., Chen,L., Cheng,B. and Fan,J.
    Engineering soluble tobacco etch virus protease accompanies the loss of stability
    Protein Expr Purif (2013) 92, 29-35. PubMed  Europe PubMed DOI
55. Raran-Kurussi,S., Tozser,J., Cherry,S., Tropea,J.E. and Waugh,D.S.
    Differential temperature dependence of tobacco etch virus and rhinovirus 3C proteases
    Anal Biochem (2013) 436, 142-144. PubMed  Europe PubMed DOI
56. Renicke,C., Spadaccini,R. and Taxis,C.
    A tobacco etch virus protease with increased substrate tolerance at the P1' position
    PLoS ONE (2013) 8, e67915-e67915. PubMed  Europe PubMed DOI
57. Wang,J.-Z., Ren,S.-Y., Zhu,G.-F., Xi,L., Han,Y.-G., Luo,Y. and Du,L.-F.
    Hg2+ interference with the structure of tobacco etch virus protease (TEVp) and its implications for biological engineering
    J Mol Struct (2013) 1052, 85-92. DOI
58. Wang,Y., Zhu,G.F., Ren,S.Y., Han,Y.G., Luo,Y. and Du,L.F.
    Insight into the structural stability of wild type and mutants of the tobacco etch virus protease with molecular dynamics simulations
    J Mol Model (2013) 19, 4865-4875. PubMed  Europe PubMed DOI
59. Yi,L., Gebhard,M.C., Li,Q., Taft,J.M., Georgiou,G. and Iverson,B.L.
    Engineering of TEV protease variants by yeast ER sequestration screening (YESS) of combinatorial libraries
    Proc Natl Acad Sci U S A (2013) 110, 7229-7234. PubMed  Europe PubMed DOI
2012
60. Han,J.S., Kim,D.H. and Choi,K.Y.
    Potyvirus NIa protease
    [ISSN:978-0-12-407743-0] (2012) 3, 2427-2432. DOI
61. Kim,T.K., Han,H.E., Kim,H., Lee,J.E., Choi,D., Park,W.J. and Han,P.L.
    Expression of the plant viral protease NIa in the brain of a mouse model of Alzheimer's disease mitigates Abeta pathology and improves cognitive function
    Exp Mol Med (2012) 44, 740-748. PubMed  Europe PubMed DOI  U
62. Miladi,B., Marjou,A.E., Boeuf,G., Bouallagui,H., Dufour,F., Di Martino,P. and Elm'selmi,A.
    Oriented immobilization of the tobacco etch virus protease for the cleavage of fusion proteins
    J Biotechnol (2012) 158, 97-103. PubMed  Europe PubMed DOI
63. Sun,C., Liang,J., Shi,R., Gao,X., Zhang,R., Hong,F., Yuan,Q. and Wang,S.
    Tobacco etch virus protease retains its activity in various buffers and in the presence of diverse additives
    Protein Expr Purif (2012) 82, 226-231. PubMed  Europe PubMed DOI
64. Verhoeven,K.D., Altstadt,O.C. and Savinov,S.N.
    Intracellular detection and evolution of site-specific proteases using a genetic selection system
    Appl Biochem Biotechnol (2012) 166, 1340-1354. PubMed  Europe PubMed DOI
65. Wei,L., Cai,X., Qi,Z., Rong,L., Cheng,B. and Fan,J.
    In vivo and in vitro characterization of TEV protease mutants
    Protein Expr Purif (2012) 83, 157-163. PubMed  Europe PubMed DOI  E
2011
66. Djannatian,M.S., Galinski,S., Fischer,T.M. and Rossner,M.J.
    Studying G protein-coupled receptor activation using split-tobacco etch virus assays
    Anal Biochem (2011) 412, 141-152. PubMed  Europe PubMed DOI
67. Kostallas,G., Lofdahl,P.A. and Samuelson,P.
    Substrate profiling of tobacco etch virus protease using a novel fluorescence-assisted whole-cell assay
    PLoS ONE (2011) 6, e16136-e16136. PubMed  Europe PubMed DOI  PMC  EPMC  P
68. Miladi,B., Bouallagui,H., Dridi,C., El Marjou,A., Boeuf,G., Di Martino,P., Dufour,F. and Elm'selmi,A.
    A new tagged-TEV protease: construction, optimisation of production, purification and test activity
    Protein Expr Purif (2011) 75, 75-82. PubMed  Europe PubMed DOI
2010
69. Boulware,K.T., Jabaiah,A. and Daugherty,P.S.
    Evolutionary optimization of peptide substrates for proteases that exhibit rapid hydrolysis kinetics
    Biotechnol Bioeng (2010) 106, 339-346. PubMed  Europe PubMed DOI  P
2009
70. Puhl,A.C., Giacomini,C., Irazoqui,G., Batista-Viera,F., Villarino,A. and Terenzi,H.
    Covalent immobilization of tobacco-etch-virus NIa protease: a useful tool for cleavage of the histidine tag of recombinant proteins
    Biotechnol Appl Biochem (2009) 53, 165-174. PubMed  Europe PubMed DOI
71. Wu,X., Wu,D., Lu,Z., Chen,W., Hu,X. and Ding,Y.
    A novel method for high-level production of TEV protease by superfolder GFP tag
    J Biomed Biotechnol (2009) 2009, 591923-591923. PubMed  Europe PubMed DOI  PMC  EPMC  E
2008
72. Harder,B., Schomburg,A., Pflanz,R., Kustner,K., Gerlach,N. and Schuh,R.
    TEV protease-mediated cleavage in Drosophila as a tool to analyze protein functions in living organisms
    Biotechniques (2008) 44, 765-772. PubMed  Europe PubMed DOI
73. Lundback,A.K., van den Berg,S., Hebert,H., Berglund,H. and Eshaghi,S.
    Exploring the activity of tobacco etch virus protease in detergent solutions
    Anal Biochem (2008) 382, 69-71. PubMed  Europe PubMed DOI
74. Pauli,A., Althoff,F., Oliveira,R.A., Heidmann,S., Schuldiner,O., Lehner,C.F., Dickson,B.J. and Nasmyth,K.
    Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons
    Dev Cell (2008) 14, 239-251. PubMed  Europe PubMed DOI  PMC  EPMC
75. Wehr,M.C., Reinecke,L., Botvinnik,A. and Rossner,M.J.
    Analysis of transient phosphorylation-dependent protein-protein interactions in living mammalian cells using split-TEV
    BMC Biotechnol (2008) 8, 55-55. PubMed  Europe PubMed DOI  PMC  EPMC
2007
76. Blommel,P.G. and Fox,B.G.
    A combined approach to improving large-scale production of tobacco etch virus protease
    Protein Expr Purif (2007) 55, 53-68. PubMed  Europe PubMed DOI  PMC  EPMC  E
77. Cabrita,L.D., Gilis,D., Robertson,A.L., Dehouck,Y., Rooman,M. and Bottomley,S.P.
    Enhancing the stability and solubility of TEV protease using in silico design
    Protein Sci (2007) 16, 2360-2367. PubMed  Europe PubMed DOI  PMC  EPMC
78. Eser,M., Henrichs,T., Boyd,D. and Ehrmann,M.
    Target-directed proteolysis in vivo
    Methods Enzymol (2007) 421, 68-83. PubMed  Europe PubMed DOI
79. Fang,L., Jia,K.Z., Tang,Y.L., Ma,D.Y., Yu,M. and Hua,Z.C.
    An improved strategy for high-level production of TEV protease in Escherichia coli and its purification and characterization
    Protein Expr Purif (2007) 51, 102-109. PubMed  Europe PubMed DOI  E
80. Kraft,M., Radke,D., Wieland,G.D., Zipfel,P.F. and Horn,U.
    A fluorogenic substrate as quantitative in vivo reporter to determine protein expression and folding of tobacco etch virus protease in Escherichia coli
    Protein Expr Purif (2007) 52, 478-484. PubMed  Europe PubMed DOI  A  E
2006
81. Kawe,M., Forrer,P., Amstutz,P. and Pluckthun,A.
    Isolation of intracellular proteinase inhibitors derived from designed ankyrin repeat proteins by genetic screening
    J Biol Chem (2006) 281, 40252-40263. PubMed  Europe PubMed DOI
82. [YEAR:5-9-2006]van den Berg,S., Lofdahl,P.A., Hard,T. and Berglund,H.
    Improved solubility of TEV protease by directed evolution
    J Biotechnol (5-9-2006) 121, 291-298. PubMed  Europe PubMed DOI
83. [YEAR:29-10-2006]Wehr,M.C., Laage,R., Bolz,U., Fischer,T.M., Grunewald,S., Scheek,S., Bach,A., Nave,K.A. and Rossner,M.J.
    Monitoring regulated protein-protein interactions using split TEV
    Nat Methods (29-10-2006) 3, 985-993. PubMed  Europe PubMed DOI
2005
84. Adams,M.J., Antoniw,J.F. and Beaudoin,F.
    Overview and analysis of the polyprotein cleavage sites in the family Potyviridae
    Mol Plant Pathol (2005) 6, 471-487. PubMed  Europe PubMed DOI  P
85. [YEAR:1-7-2005]Nunn,C.M., Jeeves,M., Cliff,M.J., Urquhart,G.T., George,R.R., Chao,L.H., Tscuchia,Y. and Djordjevic,S.
    Crystal structure of tobacco etch virus protease shows the protein C terminus bound within the active site
    J Mol Biol (1-7-2005) 350, 145-155. PubMed  Europe PubMed DOI  S
86. Tozser,J., Tropea,J.E., Cherry,S., Bagossi,P., Copeland,T.D., Wlodawer,A. and Waugh,D.S.
    Comparison of the substrate specificity of two potyvirus proteases
    FEBS J (2005) 272, 514-523. PubMed  Europe PubMed DOI  P
2004
87. Han,J.S., Kim,D.H. and Choi,K.Y.
    Potyvirus NIa protease
    [ISSN:0-12-079610-4] (2004) 2, 1376-1379.  V
2003
88. Mohanty,A.K., Simmons,C.R. and Wiener,M.C.
    Inhibition of tobacco etch virus protease activity by detergents
    Protein Expr Purif (2003) 27, 109-114. PubMed  Europe PubMed DOI
2002
89. [YEAR:28-6-2002]Kapust,R.B., Tozser,J., Copeland,T.D. and Waugh,D.S.
    The P1' specificity of tobacco etch virus protease
    Biochem Biophys Res Commun (28-6-2002) 294, 949-955. PubMed  Europe PubMed DOI  P
90. [YEAR:27-12-2002]Phan,J., Zdanov,A., Evdokimov,A.G., Tropea,J.E., Peters,H.K., III, Kapust,R.B., Li,M., Wlodawer,A. and Waugh,D.S.
    Structural basis for the substrate specificity of tobacco etch virus protease
    J Biol Chem (27-12-2002) 277, 50564-50572. PubMed  Europe PubMed DOI  P  S
2001
91. [YEAR:28-9-2001]Faber,K.N., Kram,A.M., Ehrmann,M. and Veenhuis,M.
    A novel method to determine the topology of peroxisomal membrane proteins in vivo using the tobacco etch virus protease
    J Biol Chem (28-9-2001) 276, 36501-36507. PubMed  Europe PubMed DOI
92. Kapust,R.B., Tozser,J., Fox,J.D., Anderson,D.E., Cherry,S., Copeland,T.D. and Waugh,D.S.
    Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency
    Protein Eng (2001) 14, 993-1000. PubMed  Europe PubMed
93. Lucast,L.J., Batey,R.T. and Doudna,J.A.
    Large-scale purification of a stable form of recombinant tobacco etch virus protease
    Biotechniques (2001) 30, 544-546. PubMed  Europe PubMed
2000
94. Kapust,R.B. and Waugh,D.S.
    Controlled intracellular processing of fusion proteins by TEV protease
    Protein Expr Purif (2000) 19, 312-318. PubMed  Europe PubMed DOI
95. [YEAR:1-1-2000]Melcher,K.
    A modular set of prokaryotic and eukaryotic expression vectors
    Anal Biochem (1-1-2000) 277, 109-120. PubMed  Europe PubMed DOI
96. [YEAR:30-4-2000]Yoon,H.Y., Hwang,D.C., Choi,K.Y. and Song,B.D.
    Proteolytic processing of oligopeptides containing the target sequences by the recombinant tobacco vein mottling virus NIa proteinase
    Mol Cells (30-4-2000) 10, 213-219. PubMed  Europe PubMed
1999
97. Daros,J.A., Schaad,M.C. and Carrington,J.C.
    Functional analysis of the interaction between VPg-proteinase (NIa) and RNA polymerase (NIb) of tobacco etch potyvirus, using conditional and suppressor mutants
    J Virol (1999) 73, 8732-8740. PubMed  Europe PubMed  PMC  EPMC
1998
98. Fellers,J.P., Collins,G.B. and Hunt,A.G.
    The NIa-proteinase of different plant potyviruses provides specific resistance to viral infection
    Crop Sci (1998) 38, 1309-1319.
1997
99. [YEAR:25-11-1997]Ehrmann,M., Bolek,P., Mondigler,M., Boyd,D. and Lange,R.
    TnTIN and TnTAP: mini-transposons for site-specific proteolysis in vivo
    Proc Natl Acad Sci U S A (25-11-1997) 94, 13111-13115. PubMed  Europe PubMed DOI  PMC  EPMC
100. Li,X.H., Valdez,P., Olvera,R.E. and Carrington,J.C.
     Functions of the tobacco etch virus RNA polymerase (NIb): Subcellular transport and protein-protein interaction with VPg/proteinase (NIa)
     J Virol (1997) 71, 1598-1607. PubMed  Europe PubMed  PMC  EPMC
1996
101. Schaad,M.C., Haldeman-Cahill,R., Cronin,S. and Carrington,J.C.
     Analysis of the VPg-proteinase (NIa) encoded by tobacco etch potyvirus: Effects of mutations on subcellular transport, proteolytic processing, and genome amplification
     J Virol (1996) 70, 7039-7048. PubMed  Europe PubMed  PMC  EPMC
1995
102. Parks,T.D., Howard,E.D., Wolpert,T.J., Arp,D.J. and Dougherty,W.G.
     Expression and purification of a recombinant tobacco etch virus NIa proteinase: biochemical analyses of the full-length and a naturally occurring truncated proteinase form
     Virology (1995) 210, 194-201. PubMed  Europe PubMed DOI
1992
103. Parks,T.D., Smith,H.A. and Dougherty,W.G.
     Cleavage profiles of tobacco etch virus (TEV)-derived substrates mediated by precursor and processed forms of the TEV NIa proteinase
     J Gen Virol (1992) 73, 149-155. PubMed  Europe PubMed
1991
104. Parks,T.D. and Dougherty,W.G.
     Substrate recognition by the NIa proteinase of two potyviruses involves multiple domains: characterization using genetically engineered hybrid proteinase molecules
     Virology (1991) 182, 17-27. PubMed  Europe PubMed DOI  P
1989
105. Dougherty,W.G., Parks,T.D., Cary,S.M., Bazan,J.F. and Fletterick,R.J.
     Characterization of the catalytic residues of the tobacco etch virus 49-kDa proteinase
     Virology (1989) 172, 302-310. PubMed  Europe PubMed DOI
106. Dougherty,W.G. and Parks,T.D.
     Molecular genetic and biochemical evidence for the involvement of the heptapeptide cleavage sequence in determining the reaction profile at two tobacco etch virus cleavage sites in cell-free assays
     Virology (1989) 172, 145-155. PubMed  Europe PubMed
1988
107. Carrington,J.C., Cary,S.M. and Dougherty,W.G.
     Mutational analysis of tobacco etch virus polyprotein processing: cis and trans proteolytic activities of polyproteins containing the 49-kilodalton proteinase
     J Virol (1988) 62, 2313-2320. PubMed  Europe PubMed  PMC  EPMC  P
108. Carrington,J.C. and Dougherty,W.G.
     A viral cleavage site cassette: identification of amino acid sequences required for tobacco etch virus polyprotein processing
     Proc Natl Acad Sci U S A (1988) 85, 3391-3395. PubMed  Europe PubMed  PMC  EPMC  P
1987
109. Carrington,J.C. and Dougherty,W.G.
     Small nuclear inclusion protein encoded by a plant potyvirus genome is a protease
     J Virol (1987) 61, 2540-2548. PubMed  Europe PubMed  PMC  EPMC