Literature for peptidase C03.005: hepatitis A virus-type picornain 3C

(Topics flags: S Structure, A Assay, T Target, P Specificity, I Inhibitor, E Expression, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

2024
1. Karaseva,M.A., Gramma,V.A., Safina,D.R., Lunina,N.A., Komissarov,A.A., Kostrov,S.V. and Demidyuk,I.V.
   Expression and Purification of His-Tagged Variants of Human Hepatitis A Virus 3C Protease
   Protein Pept Lett31, 305-311-311. PubMed  Europe PubMed DOI
2. Sureshan,M., Brintha,S. and Jothi,A.
   Identification of Mulberrofuran as a potent inhibitor of hepatitis A virus 3C(pro) and RdRP enzymes through structure-based virtual screening, dynamics simulation, and DFT studies
   Mol Divers28, 1609-1628. PubMed  Europe PubMed DOI  I
2023
3. Sun,L., Feng,H., Misumi,I., Shirasaki,T., Hensley,L., Gonzalez-Lopez,O., Shiota,I., Chou,W.C., Ting,J.P., Cullen,J.M., Cowley,D.O., Whitmire,J.K. and Lemon,S.M.
   Viral protease cleavage of MAVS in genetically modified mice with hepatitis A virus infection
   J Hepatol78, 271-280. PubMed  Europe PubMed DOI
2021
4. Komissarov,A.A., Karaseva,M.A., Roschina,M.P., Shubin,A.V., Lunina,N.A., Kostrov,S.V. and Demidyuk,I.V.
   Individual Expression of Hepatitis A Virus 3C Protease Induces Ferroptosis in Human Cells In Vitro
   Int J Mol Sci22, PubMed  Europe PubMed DOI
2019
5. Al-Salahi,R., Anouar,E.H., Marzouk,M. and Abuelizz,H.A.
   Anti-HAV evaluation and molecular docking of newly synthesized 3-benzyl(phenethyl)benzo[g]quinazolines
   Bioorg Med Chem Lett29, 1614-1619. PubMed  Europe PubMed DOI  I
6. Banerjee,K., Bhat,R., Rao,V.U.B., Nain,A., Rallapalli,K.L., Gangopadhyay,S., Singh,R.P., Banerjee,M. and Jayaram,B.
   Toward development of generic inhibitors against the 3C proteases of picornaviruses
   FEBS J286, 765-787. PubMed  Europe PubMed DOI  I
7. Kassem,A.F., Batran,R.Z., Abbas,E.M.H., Elseginy,S.A., Shaheen,M.N.F. and Elmahdy,E.M.
   New 4-phenylcoumarin derivatives as potent 3C protease inhibitors: design, synthesis, anti-HAV effect and molecular modeling
   Eur J Med Chem168, 447-460. PubMed  Europe PubMed DOI  I
2017
8. Sun,D., Wang,M., Wen,X., Cheng,A., Jia,R., Sun,K., Yang,Q., Wu,Y., Zhu,D., Chen,S., Liu,M., Zhao,X. and Chen,X.
   Cleavage of poly(A)-binding protein by duck hepatitis A virus 3C protease
   Sci Rep7, 16261-16261. PubMed  Europe PubMed DOI
9. Zhou,J., Wang,D., Xi,Y., Zhu,X., Yang,Y., Lv,M., Luo,C., Chen,J., Ye,X., Fang,L. and Xiao,S.
   Assessing activity of hepatitis A virus 3C protease using a cyclized luciferase-based biosensor
   Biochem Biophys Res Commun488, 621-627. PubMed  Europe PubMed DOI  A
2015
10. Shubin,A.V., Demidyuk,I.V., Lunina,N.A., Komissarov,A.A., Roschina,M.P., Leonova,O.G. and Kostrov,S.V.
    Protease 3C of hepatitis A virus induces vacuolization of lysosomal/endosomal organelles and caspase-independent cell death
    BMC Cell Biol16, 4- PubMed  Europe PubMed DOI
2014
11. Wang,D., Fang,L., Wei,D., Zhang,H., Luo,R., Chen,H., Li,K. and Xiao,S.
    Hepatitis A virus 3C protease cleaves NEMO to impair induction of beta interferon
    J Virol88, 10252-10258. PubMed  Europe PubMed DOI
2012
12. Blaum,B.S., Wunsche,W., Benie,A.J., Kusov,Y., Peters,H., Gauss-Muller,V., Peters,T. and Sczakiel,G.
    Functional binding of hexanucleotides to 3C protease of hepatitis A virus
    Nucleic Acids Res40, 3042-3055. PubMed  Europe PubMed DOI  I
13. Yin,J. and Bergmann,E.M.
    Hepatitis A virus picornain 3C
    [ISSN:978-0-12-407743-0]3, 2417-2423. DOI
2011
14. Qu,L., Feng,Z., Yamane,D., Liang,Y., Lanford,R.E., Li,K. and Lemon,S.M.
    Disruption of TLR3 signaling due to cleavage of TRIF by the hepatitis A virus protease-polymerase processing intermediate, 3CD
    PLoS Pathog7, e1002169-e1002169. PubMed  Europe PubMed DOI
15. Sellamuthu,S., Shin,B.H., Han,H.E., Park,S.M., Oh,H.J., Rho,S.H., Lee,Y.J. and Park,W.J.
    An engineered viral protease exhibiting substrate specificity for a polyglutamine stretch prevents polyglutamine-induced neuronal cell death
    PLoS ONE6, e22554-e22554. PubMed  Europe PubMed DOI  U
2010
16. Kanda,T., Gauss-Muller,V., Cordes,S., Tamura,R., Okitsu,K., Shuang,W., Nakamoto,S., Fujiwara,K., Imazeki,F. and Yokosuka,O.
    Hepatitis A virus (HAV) proteinase 3C inhibits HAV IRES-dependent translation and cleaves the polypyrimidine tract-binding protein
    J Viral Hepat17, 618-623. PubMed  Europe PubMed DOI
2008
17. Huitema,C., Zhang,J., Yin,J., James,M.N., Vederas,J.C. and Eltis,L.D.
    Heteroaromatic ester inhibitors of hepatitis A virus 3C proteinase: evaluation of mode of action
    Bioorg Med Chem16, 5761-5777. PubMed  Europe PubMed DOI  T  I
18. Sellamuthu,S., Shin,B.H., Lee,E.S., Rho,S.H., Hwang,W., Lee,Y.J., Han,H.E., Kim,J.I. and Park,W.J.
    Engineering of protease variants exhibiting altered substrate specificity
    Biochem Biophys Res Commun371, 122-126. PubMed  Europe PubMed DOI  P
19. Sperry,J. and Brimble,M.A.
    An efficient enantioselective synthesis of the 3C protease inhibitor (-)-thysanone
    Synlett2008, 1910-1912. DOI  I
2007
20. Yang,Y., Liang,Y., Qu,L., Chen,Z., Yi,M., Li,K. and Lemon,S.M.
    Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor
    Proc Natl Acad Sci U S A104, 7253-7258. PubMed  Europe PubMed DOI
21. Zhang,B., Morace,G., Gauss-Muller,V. and Kusov,Y.
    Poly(A) binding protein, C-terminally truncated by the hepatitis A virus proteinase 3C, inhibits viral translation
    Nucleic Acids Res35, 5975-5984. PubMed  Europe PubMed DOI
22. Zhang,B., Seitz,S., Kusov,Y., Zell,R. and Gauss-Muller,V.
    RNA interaction and cleavage of poly(C)-binding protein 2 by hepatitis A virus protease
    Biochem Biophys Res Commun364, 725-730. PubMed  Europe PubMed DOI
2006
23. James,M.N.
    The peptidases from fungi and viruses
    Biol Chem387, 1023-1029. PubMed  Europe PubMed DOI  S
24. [YEAR:7-7-2006]Yin,J., Cherney,M.M., Bergmann,E.M., Zhang,J., Huitema,C., Pettersson,H., Eltis,L.D., Vederas,J.C. and James,M.N.
    An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors
    J Mol Biol361, 673-686. PubMed  Europe PubMed DOI  S  I
2005
25. [YEAR:13-9-2005]Peters,H., Kusov,Y.Y., Meyer,S., Benie,A.J., Bauml,E., Wolff,M., Rademacher,C., Peters,T. and Gauss-Muller,V.
    Hepatitis A virus proteinase 3C binding to viral RNA: correlation with substrate binding and enzyme dimerization
    Biochem J385, 363-370. PubMed  Europe PubMed DOI
26. [YEAR:14-10-2005]Yin,J., Bergmann,E.M., Cherney,M.M., Lall,M.S., Jain,R.P., Vederas,J.C. and James,M.N.
    Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site
    J Mol Biol354, 854-871. PubMed  Europe PubMed DOI  S  I
2004
27. Bergmann,E.M.
    Hepatitis A virus picornain 3C
    [ISSN:0-12-079610-4]2, 1373-1376.  V
28. [YEAR:16-7-2004]Jain,R.P. and Vederas,J.C.
    Structural variations in keto-glutamines for improved inhibition against hepatitis A virus 3C proteinase
    Bioorg Med Chem Lett14, 3655-3658. PubMed  Europe PubMed DOI
29. Lall,M.S., Jain,R.P. and Vederas,J.C.
    Inhibitors of 3C cysteine proteinases from Picornaviridae
    Curr Top Med Chem4, 1239-1253. PubMed  Europe PubMed DOI  I
30. Skern,T.
    Picornain 3C
    [ISSN:0-12-079610-4]2, 1353-1357.  V
2002
31. Cohen,L., Benichou,D. and Martin,A.
    Analysis of deletion mutants indicates that the 2A polypeptide of hepatitis A virus participates in virion morphogenesis
    J Virol76, 7495-7505. PubMed  Europe PubMed DOI
32. [YEAR:8-3-2002]Lall,M.S., Ramtohul,Y.K., James,M.N. and Vederas,J.C.
    Serine and threonine beta-lactones: a new class of hepatitis a virus 3C cysteine proteinase inhibitors
    J Org Chem67, 1536-1547. PubMed  Europe PubMed DOI  I
33. [YEAR:17-5-2002]Ramtohul,Y.K., James,M.N. and Vederas,J.C.
    Synthesis and evaluation of keto-glutamine analogues as inhibitors of hepatitis A virus 3C proteinase
    J Org Chem67, 3169-3178. PubMed  Europe PubMed DOI  I
34. Ramtohul,Y.K., Martin,N.I., Silkin,L., James,M.N.G. and Vederas,J.C.
    Synthesis of pseudoxazolones and their inhibition of the 3C cysteine proteinases from hepatitis A virus and human rhinovirus-14
    J Chem Soc [Perkin 1]2002, 1351-1359.
2001
35. [YEAR:6-4-2001]Kabrane-Lazizi,Y., Emerson,S.U., Herzog,C. and Purcell,R.H.
    Detection of antibodies to HAV 3C proteinase in experimentally infected chimpanzees and in naturally infected children
    Vaccine19, 2878-2883. PubMed  Europe PubMed DOI
1999
36. [YEAR:5-12-1999]Bergmann,E.M., Cherney,M.M., Mckendrick,J., Frormann,S., Luo,C., Malcolm,B.A., Vederas,J.C. and James,M.N.
    Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis A virus (HAV) and implications for the polyprotein processing in HAV
    Virology265, 153-163. PubMed  Europe PubMed DOI  S  I
37. Huang,Y., Malcolm,B.A. and Vederas,J.C.
    Synthesis and testing of azaglutamine derivatives as inhibitors of hepatitis A virus (HAV) 3C proteinase
    Bioorg Med Chem7, 607-619. PubMed  Europe PubMed DOI  I
38. Kusov,Y. and Gauss-Muller,V.
    Improving proteolytic cleavage at the 3A/3B site of the hepatitis A virus polyprotein impairs processing and particle formation, and the impairment can be complemented in trans by 3AB and 3ABC
    J Virol73, 9867-9878. PubMed  Europe PubMed
39. Seipelt,J., Guarne,A., Bergmann,E., James,M., Sommergruber,W., Fita,I. and Skern,T.
    The structures of picornaviral proteinases
    Virus Res62, 159-168. PubMed  Europe PubMed DOI
1997
40. Bergmann,E.M., Mosimann,S.C., Chernaia,M.M., Malcolm,B.A. and James,M.N.
    The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition
    J Virol71, 2436-2448. PubMed  Europe PubMed  S
41. Gosert,R., Dollenmaier,G. and Weitz,M.
    Identification of active-site residues in protease 3C of hepatitis A virus by site-directed mutagenesis
    J Virol71, 3062-3068. PubMed  Europe PubMed
42. Morris,T.S., Frormann,S., Shechosky,S., Lowe,C., Lall,M.S., Gauss-Muller,V., Purcell,R.H., Emerson,S.U., Vederas,J.C. and Malcolm,B.A.
    In vitro and ex vivo inhibition of hepatitis A virus 3C proteinase by a peptidyl monofluoromethyl ketone
    Bioorg Med Chem5, 797-807. PubMed  Europe PubMed DOI  I
43. Ryan,M.D. and Flint,M.
    Virus-encoded proteinases of the picornavirus super-group
    J Gen Virol78, 699-723. PubMed  Europe PubMed
1996
44. Gosert,R., Cassinotti,P., Siegl,G. and Weitz,M.
    Identification of hepatitis A virus non-structural protein 2B and its release by the major virus protease 3C
    J Gen Virol77, 247-255. PubMed  Europe PubMed
1995
45. Malcolm,B.A., Lowe,C., Shechosky,S., McKay,R.T., Yang,C.C., Shah,V.J., Simon,R.J., Vederas,J.C. and Santi,D.V.
    Peptide aldehyde inhibitors of hepatitis A virus 3C proteinase
    Biochemistry34, 8172-8179. PubMed  Europe PubMed DOI  I
46. [YEAR:20-10-1995]Martin,A., Escriou,N., Chao,S.F., Girard,M., Lemon,S.M. and Wychowski,C.
    Identification and site-directed mutagenesis of the primary (2A/2B) cleavage site of the hepatitis A virus polyprotein: functional impact on the infectivity of HAV RNA transcripts
    Virology213, 213-222. PubMed  Europe PubMed DOI
47. Schultheiss,T., Sommergruber,W., Kusov,Y. and Gauss-Muller,V.
    Cleavage specificity of purified recombinant hepatitis A virus 3C proteinase on natural substrates
    J Virol69, 1727-1733. PubMed  Europe PubMed  P
1994
48. [YEAR:5-5-1994]Allaire,M., Chernaia,M.M., Malcolm,B.A. and James,M.N.
    Picornaviral 3C cysteine proteinases have a fold similar to chymotrypsin-like serine proteinases
    Nature369, 72-76. PubMed  Europe PubMed DOI  S
49. Allaire,M. and James,M.
    Deduction of the 3C proteinases' fold
    Nat Struct Biol1, 505-506. PubMed  Europe PubMed  S
50. Schultheiss,T., Kusov,Y.Y. and Gauss-Muller,V.
    Proteinase 3C of hepatitis A virus (HAV) cleaves the HAV polyprotein P2-P3 at all sites including VP1/2a and 2a/2b
    Virology198, 275-281. PubMed  Europe PubMed
51. Tesar,M., Pak,I., Jia,X.Y., Richards,O.C., Summers,D.F. and Ehrenfeld,E.
    Expression of hepatitis A virus precursor protein P3 in vivo and in vitro: polyprotein processing of the 3CD cleavage site
    Virology198, 524-533. PubMed  Europe PubMed DOI
1993
52. Chernaia,M.M., Malcolm,B.A., Allaire,M. and James,M.N.
    Hepatitis A virus 3C proteinase: some properties, crystallization and preliminary crystallographic characterization
    J Mol Biol234, 890-893. PubMed  Europe PubMed DOI
53. Jia,X.Y., Summers,D.F. and Ehrenfeld,E.
    Primary cleavage of the HAV capsid protein precursor in the middle of the proposed 2A coding region
    Virology193, 515-519. PubMed  Europe PubMed DOI
1992
54. Harmon,S.A., Updike,W., Jia,X.Y., Summers,D.F. and Ehrenfeld,E.
    Polyprotein processing in cis and in trans by hepatitis A virus 3C protease cloned and expressed in Escherichia coli
    J Virol66, 5242-5247. PubMed  Europe PubMed
55. Jewell,D.A., Swietnicki,W., Dunn,B.M. and Malcolm,B.A.
    Hepatitis A virus 3C proteinase substrate specificity
    Biochemistry31, 7862-7869. PubMed  Europe PubMed  P
56. Kusov,Y.Y., Sommergruber,W., Schreiber,M. and Gauss-Muller,V.
    Intermolecular cleavage of hepatitis A virus (HAV) precursor protein P1-P2 by recombinant HAV proteinase 3C
    J Virol66, 6794-6796. PubMed  Europe PubMed
57. Malcolm,B.A., Chin,S.M., Jewell,D.A., Stratton-Thomas,J.R., Thudium,K.B., Ralston,R. and Rosenberg,S.
    Expression and characterization of recombinant hepatitis A virus 3C proteinase
    Biochemistry31, 3358-3363. PubMed  Europe PubMed DOI  E
1991
58. Gauss-Muller,V., Jurgensen,D. and Deutzmann,R.
    Autoproteolytic cleavage of recombinant 3C proteinase of hepatitis A virus
    Virology182, 861-864. PubMed  Europe PubMed DOI
59. Jia,X.Y., Ehrenfeld,E. and Summers,D.F.
    Proteolytic activity of hepatitis A virus 3C protein
    J Virol65, 2595-2600. PubMed  Europe PubMed
1988
60. Krausslich,H.G. and Wimmer,E.
    Viral proteinases
    Annu Rev Biochem57, 701-754. PubMed  Europe PubMed DOI
1984
61. Blinov,V.M., Gorbalenia,A.E. and Donchenko,A.P.
    [Structural similarity of poliovirus cysteine proteinase P3-7c and cellular serine proteinase of trypsin]
    Dokl Akad Nauk SSSR279, 502-505. PubMed  Europe PubMed