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Literature for peptidase C02.011: calpain-5

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature

(Topics flags: S Structure, M Mutation, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Gal,J., Dufour,A., Young,D., Yang,E.S. and Geddes,J.W.
    The Identification of Proteolytic Substrates of Calpain-5 with N-Terminomics
    Int J Mol Sci (2025) 26 PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2024
  2. Chukai,Y., Ito,G., Miki,Y., Wakabayashi,K., Itoh,K., Sugano,E., Tomita,H., Fukuda,T. and Ozaki,T.
    Role of calpain-5 in cerebral ischemia and reperfusion injury
    Biochim Biophys Acta Gen Subj (2024) 1868, 130506-130506. PubMed  Europe PubMed DOI  K
  3. Morishima,N. and Ito,Y.
    Calpain-5 regulates muscle-specific protein expression and nuclear positioning during myoblast differentiation
    J Biol Chem (2024) , 107842-107842. PubMed  Europe PubMed DOI  K
    4. 2023
  4. Geddes,J.W., Bondada,V., Croall,D.E., Rodgers,D.W. and Gal,J.
    Impaired activity and membrane association of most calpain-5 mutants causal for neovascular inflammatory vitreoretinopathy
    Biochim Biophys Acta Mol Basis Dis (2023) 1869, 166747-166747. PubMed  Europe PubMed DOI  PMC  EPMC
    5. 2022
  5. Chukai,Y., Ito,G., Konno,M., Sakata,Y. and Ozaki,T.
    Mitochondrial calpain-5 truncates caspase-4 during endoplasmic reticulum stress
    Biochem Biophys Res Commun (2022) 608, 156-162. PubMed  Europe PubMed DOI  K
  6. Gal,J., Bondada,V., Mashburn,C.B., Rodgers,D.W., Croall,D.E. and Geddes,J.W.
    S-acylation regulates the membrane association and activity of Calpain-5
    Biochim Biophys Acta Mol Cell Res (2022) 1869, 119298-119298. PubMed  Europe PubMed DOI
  7. Nakashima,N., Nakashima,K., Nakashima,A. and Takano,M.
    Olfactory marker protein is unlikely to be cleaved by calpain 5
    Mol Brain (2022) 15, 87-87. PubMed  Europe PubMed DOI  PMC  EPMC
    8. 2021
  8. Bondada,V., Gal,J., Mashburn,C., Rodgers,D.W., Larochelle,K.E., Croall,D.E. and Geddes,J.W.
    The C2 domain of calpain 5 contributes to enzyme activation and membrane localization
    Biochim Biophys Acta Mol Cell Res (2021) 1868, 119019-119019. PubMed  Europe PubMed DOI
  9. Chukai,Y., Iwamoto,T., Itoh,K., Tomita,H. and Ozaki,T.
    Characterization of mitochondrial calpain-5
    Biochim Biophys Acta Mol Cell Res (2021) 1868, 118989-118989. PubMed  Europe PubMed DOI
    10. 2020
  10. Tang,P.H., Chemudupati,T., Wert,K.J., Folk,J.C., Mahajan,M., Tsang,S.H., Bassuk,A.G. and Mahajan,V.B.
    Phenotypic variance in calpain-5 retinal degeneration
    Am J Ophthalmol Case Rep (2020) 18, 100627-100627. PubMed  Europe PubMed DOI  PMC  EPMC  M
  11. Velez,G., Sun,Y.J., Khan,S., Yang,J., Herrmann,J., Chemudupati,T., MacLaren,R.E., Gakhar,L., Wakatsuki,S., Bassuk,A.G. and Mahajan,V.B.
    Structural insights into the unique activation mechanisms of a non-classical calpain and its disease-causing variants
    Cell Rep (2020) 30, 881-892. PubMed  Europe PubMed DOI  S
    12. 2018
  12. Coomer,C.E. and Morris,A.C.
    Capn5 expression in the healthy and regenerating zebrafish retina
    Invest Ophthalmol Vis Sci (2018) 59, 3643-3654. PubMed  Europe PubMed DOI  PMC  EPMC  M
  13. Iwamoto,T., Ishiyama,E., Ishida,K., Yamashita,T., Tomita,H. and Ozaki,T.
    Presence of calpain-5 in mitochondria
    Biochem Biophys Res Commun (2018) 504, 454-459. PubMed  Europe PubMed DOI
  14. Velez,G., Bassuk,A.G., Schaefer,K.A., Brooks,B., Gakhar,L., Mahajan,M., Kahn,P., Tsang,S.H., Ferguson,P.J. and Mahajan,V.B.
    A novel de novo CAPN5 mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay
    Cold Spring Harb Mol Case Stud (2018) 4, a002519-a002519. PubMed  Europe PubMed DOI  M
    15. 2016
  15. Gakhar,L., Bassuk,A.G., Velez,G., Khan,S., Yang,J., Tsang,S.H. and Mahajan,V.B.
    Small-angle X-ray scattering of calpain-5 reveals a highly open conformation among calpains
    J Struct Biol (2016) 196, 309-318. PubMed  Europe PubMed DOI  S
  16. Schaefer,K.A., Toral,M.A., Velez,G., Cox,A.J., Baker,S.A., Borcherding,N.C., Colgan,D.F., Bondada,V., Mashburn,C.B., Yu,C.G., Geddes,J.W., Tsang,S.H., Bassuk,A.G. and Mahajan,V.B.
    Calpain-5 expression in the retina localizes to photoreceptor synapses
    Invest Ophthalmol Vis Sci (2016) 57, 2509-2521. PubMed  Europe PubMed DOI  PMC  EPMC  M
    17. 2015
  17. Wert,K.J., Bassuk,A.G., Wu,W.H., Gakhar,L., Coglan,D., Mahajan,M., Wu,S., Yang,J., Lin,C.S., Tsang,S.H. and Mahajan,V.B.
    CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model
    Hum Mol Genet (2015) 24, 4584-4598. PubMed  Europe PubMed DOI  M
    18. 2014
  18. Wert,K.J., Skeie,J.M., Bassuk,A.G., Olivier,A.K., Tsang,S.H. and Mahajan,V.B.
    Functional validation of a human CAPN5 exome variant by lentiviral transduction into mouse retina
    Hum Mol Genet (2014) 23, 2665-2677. PubMed  Europe PubMed DOI  M
    19. 2007
  19. [YEAR:16-1-2007]Saez,M.E., Martinez-Larrad,M.T., Ramirez-Lorca,R., Gonzalez-Sanchez,J.L., Zabena,C., Martinez-Calatrava,M.J., Gonzalez,A., Moron,F.J., Ruiz,A. and Serrano-Rios,M.
    Calpain-5 gene variants are associated with diastolic blood pressure and cholesterol levels
    BMC Med Genet (16-1-2007) 8, 1-1. PubMed  Europe PubMed DOI  PMC  EPMC  M
    20. 2006
  20. [YEAR:5-1-2006]Gonzalez,A., Saez,M.E., Aragon,M.J., Galan,J.J., Vettori,P., Molina,L., Rubio,C., Real,L.M., Ruiz,A. and Ramirez-Lorca,R.
    Specific haplotypes of the CALPAIN-5 gene are associated with polycystic ovary syndrome
    Hum Reprod (5-1-2006) 21, 943-951. PubMed  Europe PubMed DOI  M
    21. 2004
  21. Sorimachi,H.
    Other calpains
    [ISSN:0-12-079610-4] (2004) 2, 1217-1225.  V
  22. [YEAR:5-11-2004]Waghray,A., Wang,D.S., McKinsey,D., Hayes,R.L. and Wang,K.K.
    Molecular cloning and characterization of rat and human calpain-5
    Biochem Biophys Res Commun (5-11-2004) 324, 46-51. PubMed  Europe PubMed DOI
    23. 1999
  23. Dear,T.N. and Boehm,T.
    Diverse mRNA expression patterns of the mouse calpain genes Capn5, Capn6 and Capn11 during development
    Mech Dev (1999) 89, 201-209. PubMed  Europe PubMed DOI
    24. 1998
  24. [YEAR:15-2-1998]Matena,K., Boehm,T. and Dear,N.
    Genomic organization of mouse Capn5 and Capn6 genes confirms that they are a distinct calpain subfamily
    Genomics (15-2-1998) 48, 117-120. PubMed  Europe PubMed DOI
    25. 1997
  25. [YEAR:1-10-1997]Dear,N., Matena,K., Vingron,M. and Boehm,T.
    A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution
    Genomics (1-10-1997) 45, 175-184. PubMed  Europe PubMed DOI
  26. [YEAR:29-10-1997]Mugita,N., Kimura,Y., Ogawa,M., Saya,H. and Nakao,M.
    Identification of a novel, tissue-specific calpain htra-3; a human homologue of the Caenorhabditis elegans sex determination gene
    Biochem Biophys Res Commun (29-10-1997) 239, 845-850. PubMed  Europe PubMed DOI

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